Post-transcriptional regulation in osteoblasts using localized delivery of miR-29a inhibitor from nanofibers to enhance extracellular matrix deposition

Acta Biomaterialia

Volumn 10, Issue 8, 2014, Pages 3571-3580

  James, Eric N ^a   Delany, Anne M ^a   Nair, Lakshmi S ^a,b  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Bone; Extracellular matrix; microRNA; Nanofibers; Osteonectin

Indexed keywords

BONE; CELL CULTURE; CELLS; COLLAGEN; DEPOSITION; RNA; SCAFFOLDS (BIOLOGY);

EXTRACELLULAR MATRICES; EXTRACELLULAR MATRIX DEPOSITION; GELATIN NANOFIBERS; LOCALISED; LOCALIZED DELIVERY; OSTEONECTIN; POST-TRANSCRIPTIONAL; POST-TRANSCRIPTIONAL REGULATIONS; SKELETAL BIOLOGY; TRANSCRIPTIONAL REGULATOR;

NANOFIBERS;

BIOLOGICAL PRODUCT; COLLAGEN; GELATIN; MESSENGER RNA; MICRORNA 29 INHIBITOR; MOLECULAR SCAFFOLD; OSTEONECTIN; RNA DERIVATIVE; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; MICRORNA; MIRN29 MICRORNA, MOUSE; NANOCAPSULE; NANOFIBER; OLIGONUCLEOTIDE;

3T3 CELL LINE; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL STRUCTURE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ELECTROSPINNING; EXTRACELLULAR MATRIX; MOUSE; NANOPHARMACEUTICS; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PROCESSING; REGULATORY MECHANISM; STROMA CELL; TRANSGENIC MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; RNA PROCESSING; ULTRASTRUCTURE;

MURINAE; MUS;

ANIMALS; BALB 3T3 CELLS; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; MICE; MICRORNAS; NANOCAPSULES; NANOFIBERS; OLIGONUCLEOTIDES; OSTEOBLASTS; RNA PROCESSING, POST-TRANSCRIPTIONAL;

EID: 84903727178     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.04.026     Document Type: Article

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