A functional variant in the neuropeptide S receptor 1 gene moderates the influence of urban upbringing on stress processing in the amygdala

Stress

Volumn 17, Issue 4, 2014, Pages 352-361

  Streit, Fabian ^a,b   Haddad, Leila ^a   Paul, Torsten ^a   Frank, Josef ^a   Schäfer, Axel ^a   Nikitopoulos, Jörg ^a   Akdeniz, Ceren ^a   Lederbogen, Florian ^a   Treutlein, Jens ^a   Witt, Stephanie ^a   Meyer Lindenberg, Andreas ^a   Rietschel, Marcella ^a   Kirsch, Peter ^a   Wüst, Stefan ^a,c  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^b UNIVERSITY OF TRIER   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Amygdala; FMRI; Gene environment interaction; HPA axis; Neuropeptide receptor gene; Psychosocial stress; Urban upbringing

Indexed keywords

CORTICOTROPIN; G PROTEIN COUPLED RECEPTOR; HYDROCORTISONE; NEUROPEPTIDE S RECEPTOR 1; UNCLASSIFIED DRUG; NPSR1 PROTEIN, HUMAN;

AMYGDALOID NUCLEUS; ANXIETY; ARTICLE; CEREBELLUM; CORPUS STRIATUM; DNA EXTRACTION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HEART RATE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MENTAL STRESS; NERVE POTENTIAL; NEUROIMAGING; PHENOTYPE; PRIORITY JOURNAL; RURAL AREA; THALAMUS; URBAN AREA; ADULT; GENETICS; HEALTH; MENTAL DISEASE; METABOLISM; PHYSIOLOGY; YOUNG ADULT;

ADULT; AMYGDALA; ANXIETY; FEMALE; GENE-ENVIRONMENT INTERACTION; GENOTYPE; HUMANS; HYDROCORTISONE; MALE; MENTAL DISORDERS; PHENOTYPE; RECEPTORS, G-PROTEIN-COUPLED; STRESS, PSYCHOLOGICAL; URBAN HEALTH; YOUNG ADULT;

EID: 84903724801     PISSN: 10253890     EISSN: 16078888     Source Type: Journal    
DOI: 10.3109/10253890.2014.921903     Document Type: Article

References (50)

1. Bush G, Luu P, Posner MI. (2000). Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4(6):215-22. (Pubitemid 30332147)
2. Cardno AG, Gottesman II. (2000). Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics. Am J Med Genet 97(1):12-17.
3. Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. (2010). Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 167(5):509-27.
4. Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, Mcclay J, Mill J, et al. (2003). Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301(5631):386-9. (Pubitemid 36877077)
5. Chauveau F, Lange MD, Jungling K, Lesting J, Seidenbecher T, Pape HC. (2012). Prevention of stress-impaired fear extinction through neuropeptide S action in the lateral amygdala. Neuropsychopharmacology 37(7):1588-99.
6. Chrousos GP. (2009). Stress and disorders of the stress system. Nat Rev Endocrinol 5(7):374-81.
7. Clark SD, Duangdao DM, Schulz S, Zhang L, Liu X, Xu YL, Reinscheid RK. (2011). Anatomical characterization of the neuropeptide S system in the mouse brain by in situ hybridization and immunohistochemistry. J Comp Neurol 519(10):1867-93.
8. Dannlowski U, Kugel H, Franke F, Stuhrmann A, Hohoff C, Zwanzger P, Lenzen T, et al. (2011). Neuropeptide-S (NPS) receptor genotype modulates basolateral amygdala responsiveness to aversive stimuli. Neuropsychopharmacology 36(9):1879-85.
9. Dedovic K, Renwick R, Mahani NK, Engert V, Lupien SJ, Pruessner JC. (2005). The Montreal Imaging Stress Task: using functional imaging to investigate the effects of perceiving and processing psychosocial stress in the human brain. J Psychiatry Neurosci 30(5):319-25. (Pubitemid 41475339)
10. Dick DM. (2011). Gene-environment interaction in psychological traits and disorders. Annu Rev Clin Psychol 7:383-409.
11. Dickerson SS, Kemeny ME. (2004). Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychol Bull 130(3):355-91. (Pubitemid 38614661)
12. Domschke K, Reif A, Weber H, Richter J, Hohoff C, Ohrmann P, Pedersen A, et al. (2011). Neuropeptide S receptor gene -converging evidence for a role in panic disorder. Mol Psychiatry 16(9):938-48.
13. Dressendorfer RA, Kirschbaum C, Rohde W, Stahl F, Strasburger CJ. (1992). Synthesis of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement. J Steroid Biochem Mol Biol 43(7):683-92.
14. Duncan LE, Keller MC. (2011). A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. Am J Psychiatry 168(10):1041-9.
15. Ebner K, Rjabokon A, Pape HC, Singewald N. (2011). Increased in vivo release of neuropeptide S in the amygdala of freely moving rats after local depolarisation and emotional stress. Amino Acids 41(4):991-6.
16. Federenko IS, Nagamine M, Hellhammer DH, Wadhwa PD, Wu?st S. (2004). The heritability of hypothalamus pituitary adrenal axis responses to psychosocial stress is context dependent. J Clin Endocrinol Metab 89(12):6244-50. (Pubitemid 39628440)
17. Gianaros PJ, Jennings JR, Sheu LK, Derbyshire SW, Matthews KA. (2007). Heightened functional neural activation to psychological stress covaries with exaggerated blood pressure reactivity. Hypertension 49(1):134-40. (Pubitemid 46360352)
18. Holzschneider K, Mulert C. (2011). Neuroimaging in anxiety disorders. Dialogues Clin Neurosci 13(4):453-61.
19. Jungling K, Liu X, Lesting J, Coulon P, Sosulina L, Reinscheid RK, Pape HC. (2012). Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor. J Physiol 590(Pt 16):3701-17.
20. Kendler KS, Gardner CO, Lichtenstein P. (2008). A developmental twin study of symptoms of anxiety and depression: evidence for genetic innovation and attenuation. Psychol Med 38(11):1567-75.
21. Kirschbaum C, Pirke KM, Hellhammer DH. (1993). The 'Trier Social Stress Test' -a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28(1-2):76-81.
22. Klauke B, Deckert J, Zwanzger P, Baumann C, Arolt V, Pauli P, Reif A, Domschke K. (2014). Neuropeptide S receptor gene (NPSR) and life events: G-E effects on anxiety sensitivity and its subdimensions. World J Biol Psychiatry 15(1):17-25.
23. Krabbendam L, Van Os J. (2005). Schizophrenia and urbanicity: a major environmental influence -conditional on genetic risk. Schizophr Bull 31(4):795-9. (Pubitemid 41437771)
24. Kudielka BM, Hellhammer DH, Wu?st S. (2009). Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. Psychoneuroendocrinology 34(1): 2-18.
25. Kumsta R, Chen FS, Pape HC, Heinrichs M. (2013). Neuropeptide S receptor gene is associated with cortisol responses to social stress in humans. Biol Psychol 93(2):304-7.
26. Lederbogen F, Kirsch P, Haddad L, Streit F, Tost H, Schuch P, Wu?st S, et al. (2011). City living and urban upbringing affect neural social stress processing in humans. Nature 474(7352):498-501.
27. Leonard SK, Ring RH. (2011). Immunohistochemical localization of the neuropeptide S receptor in the rat central nervous system. Neuroscience 172:153-63.
28. Mier D, Kirsch P, Meyer-Lindenberg A. (2010). Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis. Mol Psychiatry 15(9):918-27.
29. Monk CS. (2008). The development of emotion-related neural circuitry in health and psychopathology. Dev Psychopathol 20(4): 1231-50.
30. Muehlhan M, Lueken U, Wittchen HU, Kirschbaum C. (2011). The scanner as a stressor: evidence from subjective and neuroendocrine stress parameters in the time course of a functional magnetic resonance imaging session. Int J Psychophysiol 79(2): 118-26.
31. Munafo MR, Brown SM, Hariri AR. (2008). Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. Biol Psychiat 63(9):852-7. (Pubitemid 351458448)
32. Okamura N, Hashimoto K, Iyo M, Shimizu E, Dempfle A, Friedel S. (2007). Gender-specific association of a functional coding polymorphism in the neuropeptide S receptor gene with panic disorder but not with schizophrenia or attention-deficit/hyperactivity disorder. Prog Neuropsychopharmacol Biol Psychiatry 31:1444-8. (Pubitemid 47302566)
33. Pedersen CB, Mortensen PB. (2001). Evidence of a dose-response relationship between urbanicity during upbringing and schizophrenia risk. Arch Gen Psychiatry 58(11):1039-46. (Pubitemid 33051829)
34. Peen J, Schoevers RA, Beekman AT, Dekker J. (2010). The current status of urban-rural differences in psychiatric disorders. Acta Psychiatr Scand 121(2):84-93.
35. Peters M, Battista C. (2008). Applications of mental rotation figures of the Shepard and Metzler type and description of a mental rotation stimulus library. Brain Cogn 66(3):260-4. (Pubitemid 351296372)
36. Polanczyk G, Caspi A, Williams B, Price TS, Danese A, Sugden K, et al. (2009). Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension. Arch Gen Psychiatry 66(9):978-85.
37. Pruessner JC, Dedovic K, Khalili-Mahani N, Engert V, Pruessner M, Buss C, Renwick R, et al. (2008). Deactivation of the limbic system during acute psychosocial stress: evidence from positron emission tomography and functional magnetic resonance imaging studies. Biol Psychiatry 63(2):234-40.
38. Raczka KA, Gartmann N, Mechias ML, Reif A, Buchel C, Deckert J, Kalisch R. (2010). A neuropeptide S receptor variant associated with overinterpretation of fear reactions: a potential neurogenetic basis for catastrophizing. Mol Psychiatry 15(11):67-74.
39. Radua J, Borgwardt S, Crescini A, Mataix-Cols D, Meyer-Lindenberg A, Mcguire PK, Fusar-Poli P. (2012). Multimodal meta-analysis of structural and functional brain changes in first episode psychosis and the effects of antipsychotic medication. Neurosci Biobehav Rev 36(10):2325-33.
40. Reinscheid RK. (2008). Neuropeptide S: anatomy, pharmacology, genetics and physiological functions. Results Probl Cell Differ 46: 145-58.
41. Reinscheid RK, Xu YL, Okamura N, Zeng J, Chung S, Pai R. (2005). Pharmacological characterization of human and murine neuropeptide S receptor variants. J Pharmacol Exp Ther 315: 1338-45. (Pubitemid 41635423)
42. Smith KL, Patterson M, Dhillo WS, Patel SR, Semjonous NM, Gardiner JV, Ghatei MA, Bloom SR. (2006). Neuropeptide S stimulates the hypothalamo- pituitary-adrenal axis and inhibits food intake. Endocrinology 147(7):3510-18. (Pubitemid 43901142)
43. Strick PL, Dum RP, Fiez JA. (2009). Cerebellum and nonmotor function. Annu Rev Neurosci 32:413-34.
44. Sullivan PF, Neale MC, Kendler KS. (2000). Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry 157(10): 1552-62.
45. Taylor SE, Eisenberger NI, Saxbe D, Lehman BJ, Lieberman MD. (2006). Neural responses to emotional stimuli are associated with childhood family stress. Biol Psychiatry. 60(3):296-301. (Pubitemid 44093442)
46. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, Mazoyer B, Joliot M. (2002). Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. NeuroImage 15(1): 273-89. (Pubitemid 34852226)
47. Van Os J, Pedersen CB, Mortensen PB. (2004). Confirmation of synergy between urbanicity and familial liability in the causation of psychosis. Am J Psychiatry 161(12):2312-14. (Pubitemid 39587300)
48. Wu? st S, Federenko I, Hellhammer DH, Kirschbaum C. (2000). Genetic factors, perceived chronic stress, and the free cortisol response to awakening. Psychoneuroendocrinology 25(7):707-20.
49. Xu YL, Reinscheid RK, Huitron-Resendiz S, Clark SD, Wang Z, Lin SH, Brucher FA, et al. (2004). Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects. Neuron 43(4): 487-97. (Pubitemid 39094676)
50. Zink CF, Tong Y, Chen Q, Bassett DS, Stein JL, Meyer-Lindenberg A. (2008). Know your place: neural processing of social hierarchy in humans. Neuron 58(2):273-83. (Pubitemid 351545836)