Increased basal oxidation of peroxiredoxin 2 and limited peroxiredoxin recycling in glucose-6-phosphate dehydrogenase-deficient erythrocytes from newborn infants

FASEB Journal

Volumn 28, Issue 7, 2014, Pages 3205-3210

  Cheah, Fook Choe ^a   Peskin, Alexander V ^b   Wong, Fei Liang ^a   Ithnin, Azlin ^a   Othman, Ainoon ^c   Winterbourn, Christine C ^b  

^a UNIVERSITI KEBANGSAAN MALAYSIA MEDICAL CENTER   (Malaysia)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UNIVERSITI SAINS ISLAM MALAYSIA   (Malaysia)

Author keywords

Antioxidant defense; Hemolytic anemia; Hydrogen peroxide

Indexed keywords

BILIRUBIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HYDROGEN PEROXIDE; PEROXIREDOXIN 2;

ANTIOXIDANT ACTIVITY; ARTICLE; BILIRUBIN BLOOD LEVEL; BIOACCUMULATION; BLOOD SAMPLING; CONTROLLED STUDY; ENZYME METABOLISM; ENZYME MODIFICATION; ERYTHROCYTE; FEMALE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEMOLYSIS; HUMAN; MAJOR CLINICAL STUDY; MALAYSIA; MALE; NEONATAL HYPERBILIRUBINEMIA; NEWBORN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PEROXIREDOXIN RECYCLING; PHOTOTHERAPY; PRIORITY JOURNAL; REDUCTION; WESTERN BLOTTING;

ANTIOXIDANT DEFENSE; HEMOLYTIC ANEMIA; HYDROGEN PEROXIDE;

ANTIOXIDANTS; ERYTHROCYTES; FEMALE; GLUCOSE-6-PHOSPHATE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; HOMEODOMAIN PROTEINS; HUMANS; HYDROGEN PEROXIDE; INFANT; INFANT, NEWBORN; MALE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXIREDOXINS;

EID: 84903723061     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-250050     Document Type: Article

References (27)

1. Cappellini, M. D., and Fiorelli, G. (2008) Glucose-6-phosphate dehydrogenase deficiency. Lancet 371, 64-74
2. Beutler, E. (2008) Glucose-6-phosphate dehydrogenase deficiency: a historical perspective. Blood 111, 16-24
3. Nkhoma, E. T., Poole, C., Vannappagari, V., Hall, S. A., and Beutler, E. (2009) The global prevalence of glucose-6-phos-phate dehydrogenase deficiency: a systematic review and meta-analysis. Blood Cells Mol. Dis. 42, 267-278
4. Stanton, R. C. (2012) Glucose-6-phosphate dehydrogenase, NADPH, and cell survival. IUBMB Life 64, 362-369
5. Winterbourn, C. C. (1985) Free-radical production and oxida-tive reactions of hemoglobin. Environ. Health Perspect. 64, 321-330 (Pubitemid 16135800)
6. Mason, P. J., Bautista, J. M., and Gilsanz, F. (2007) G6PD deficiency: the genotype-phenotype association. Blood Rev. 21, 267-283 (Pubitemid 47212602)
7. Gaetani, G. F., Ferraris, A. M., Rolfo, M., Mangerini, R., Arena, S., and Kirkman, H. N. (1996) Predominant role of catalase in the disposal of hydrogen peroxide within human erythrocytes. Blood 87, 1595-1599 (Pubitemid 26056926)
8. Hochstein, P. (1988) Perspectives on hydrogen peroxide and drug-induced hemolytic anemia in glucose-6-phosphate dehy-drogenase deficiency. Free Radic. Biol. Med. 5, 387-392 (Pubitemid 19024289)
9. Low, F. M., Hampton, M. B., and Winterbourn, C. C. (2008) Peroxiredoxin 2 and peroxide metabolism in the erythrocyte. Antioxid. Redox Signal. 10, 1621-1630
10. Rhee, S. G., and Woo, H. A. (2011) Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger HO, and protein chaperones. Antioxid. Redox Signal 15, 781-794
11. Hall, A., Karplus, P. A., and Poole, L. B. (2009) Typical 2-Cys peroxiredoxins-structures, mechanisms and functions. FEBS J. 276, 2469-2477
12. Peskin, A. V., Cox, A. G., Nagy, P., Morgan, P. E., Hampton, M. B., Davies, M.J., and Winterbourn, C. C. (2010) Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3. Biochem. J. 432, 313-321
13. Moore, R., Mankad, M., Shriver, S., Mankad, V., and Plishker, G. (1991) Reconstitution of Ca(2+)-dependent K+ transport in erythrocyte membrane vesicles requires a cytoplasmic protein. J. Biol. Chem. 266, 18964-18968 (Pubitemid 21908177)
14. Low, F. M., Hampton, M. B., Peskin, A. V., and Winterbourn, C. C. (2007) Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte. Blood 109, 2611-2617 (Pubitemid 46425910)
15. Johnson, R. M., Goyette, G., Jr., Ravindranath, Y., and Ho, Y. S. (2005) Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes. Free Radic. Biol. Med. 39, 1407-1417 (Pubitemid 41547221)
16. Johnson, R. M., Ho, Y. S., Yu, D.Y., Kuypers, F. A., Ravindranath, Y, and Goyette, G. W. (2010) The effects of disruption of genes for peroxiredoxin-2, glutathione peroxidase-1, and catalase on erythrocyte oxidative metabolism. Free Radic. Biol. Med. 48, 519-525
17. Cho, C. S., Lee, S., Lee, G. T., Woo, H. A., Choi, E. J., and Rhee, S. G. (2010) Irreversible inactivation of glutathione peroxidase 1 and reversible inactivation of peroxiredoxin II by H2O2 in red blood cells. Antioxid. Redox Sig. 12, 1235-1246
18. Lee, T. H., Kim, S. U., Yu, S. L., Kim, S. H., Park, D. S., Moon, H. B., Dho, S. H., Kwon, K. S., Kwon, H. J., Han, Y H., Jeong, S., Kang, S. W., Shin, H. S., Lee, K. K., Rhee, S. G., and Yu, D. Y (2003) Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood 101, 5033-5038 (Pubitemid 36857770)
19. Nagababu, E., Mohanty, J. G., Friedman, J. S., and Rifkind, J. M. (2013) Role of peroxiredoxin-2 in protecting RBCs from hydrogen peroxide-induced oxidative stress. Free. Radic. Res. 47, 164-171
20. Bayer, S. B., Maghzal, G., Stocker, R., Hampton, M. B., and Winterbourn, C. C. (2013) Neutrophil-mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation. FASEBJ. 27, 3315-3322
21. Peskin, A. V., Low, F. M., Paton, L. N., Maghzal, G. J., Hampton, M. B., and Winterbourn, C. C. (2007) The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents. J. Biol. Chem. 282, 11885-11892 (Pubitemid 47100684)
22. American Academy of Pediatrics (2004) Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 114, 297-316
23. Azma, R. Z., Hidayati, N., Farisah, N. R., Hamidah, N. H., and Ainoon, O. (2010) G6PD enzyme activity in normal term Malaysian neonates and adults using a OSMMR2000-D kit with Hb normalization. Southeast Asian J. Trop. Med. Publ. Health 41, 982-988
24. WHO Working Group. (1989) Glucose-6-phosphate dehydrogenase deficiency. Bull. WHO 67, 601-611
25. Poynton, R. A., and Hampton, M. B. (2014) Peroxiredoxins as biomarkers of oxidative stress. Biochim. Biophys. Acta 1840, 906-912
26. Winterbourn, C. C, and Stern, A. (1987) Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical. J. Clin. Invest. 80, 1486-1491 (Pubitemid 18027795)
27. Seidman, D. S., Shiloh, M., Stevenson, D. K., Vreman, H. J., and Gale, R. (1995) Role of hemolysis in neonatal jaundice associated with glucose-6 phosphate dehydrogenase deficiency. J. Pediatr. 127, 804-806