Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma

Radiology and Oncology

Volumn 48, Issue 2, 2014, Pages 163-172

  Goricar, Katja ^a   Kovac, Viljem ^b   Dolzan, Vita ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b INSTITUTE OF ONCOLOGY   (Slovenia)

Author keywords

Folate pathway; Mesothelioma; Pemetrexed; Polymorphism; Toxicity

Indexed keywords

FOLIC ACID; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 4; PEMETREXED; SOLUTE CARRIER ORGANIC ANION TRANSPORTER 1B1;

ADULT; AGED; ALLELE; ARTICLE; CAG REPEAT; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER SURVIVAL; CHEMOTHERAPY INDUCED ANEMIA; CLINICAL ARTICLE; DRUG EFFICACY; FEBRILE NEUTROPENIA; FEMALE; FOLATE METABOLISM; GASTROINTESTINAL TOXICITY; HAPLOTYPE; HETEROZYGOTE; HUMAN; LEUKOPENIA; LIVER TOXICITY; MALE; MTHFD1 GENE; NEPHROTOXICITY; OVERALL SURVIVAL; PHARMACOGENETICS; PHASE 2 CLINICAL TRIAL (TOPIC); PLEURA MESOTHELIOMA; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM; THROMBOCYTOPENIA; TOXICITY TESTING; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR GENE;

EID: 84903722192     PISSN: 13182099     EISSN: 15813207     Source Type: Journal    
DOI: 10.2478/raon-2013-0086     Document Type: Article

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