Cancer site-specific isoforms of ENOX2 (tNOX), a cancer-specific cell surface oxidase

Clinical Proteomics

Volumn 5, Issue 1, 2009, Pages 46-51

  Hostetler, Brandon ^a   Weston, Nicole ^a   Kim, Chinpal ^a   Morré, Dorothy M ^b   Morré, D James ^c  

^a NOX Technologies Inc   (United States)

^b PURDUE UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

Cancer site specific isoforms; ECTO NOX; ENOX2; Pan ENOX2 recombinant antibody; Proteomics; TNOX; Two dimensional gel electrophoresis

Indexed keywords

CELL SURFACE PROTEIN; PROTEIN ENOX 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER DIAGNOSIS; CANCER LOCALIZATION; CONTROLLED STUDY; HUMAN; ISOELECTRIC POINT; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEOMICS; TISSUE SPECIFICITY;

EID: 70349115265     PISSN: 15426416     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12014-008-9016-x     Document Type: Article

References (20)

1. Baserga R. The biology of cell reproduction. Cambridge, MA: Harvard University Press; 1985.
2. 91 phox TIBS 25 549 561
3. DJ Morre R Pogue DM Morre 1999 A multifunctional ubiquinol oxidase of the external cell surface and sera BioFactors 9 179 187 10416030 10.1002/biof.5520090213 1:CAS:528:DyaK1MXkt12msb8%3D
4. DJ Morre C Kim C Hicks-Berger 2006 ATP-dependent and drug-inhibited vesicle enlargement reconstituted using synthetic lipids and recombinant proteins BioFactors 28 105 117 17379941 10.1002/biof.5520280205 1:CAS:528:DC%2BD2sXjt1Srurw%3D
5. DJ Morre DM Morre 2003 Cell surface NADH oxidases (ECTO-NOX proteins) with roles in cancer, cellular time-keeping, growth, aging and neurodegenerative disease Free Radical Res 37 795 808 10.1080/1071576031000083107 1:CAS:528:DC%2BD3sXlvF2htbY%3D (Pubitemid 36939596)
6. M Bruno AO Brightman J Lawrence D Werderitsh DM Morré DJ Morré 1992 Stimulation of NADH oxidase activity from rat liver plasma membranes by growth factors and hormones is decreased or absent with hepatoma plasma membranes Biochem J 284 625 628 1622384 1:CAS:528:DyaK38XksVGltb4%3D
7. Morre DJ. NADH oxidase: a multifunctional ectoprotein of the eukaryotic cell surface. In: Asard H, Berczi A, Caubergs R, editors. Plasma membrane redox systems and their role in biological stress and disease. The Netherlands: Kluwer, Dordrecht; 1998. p. 121-56.
8. PJ Chueh C Kim NM Cho DM Morré DJ Morré 2002 Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface Biochemistry 41 3732 3741 11888291 10.1021/bi012041t 1:CAS:528: DC%2BD38XhtlOktrk%3D (Pubitemid 34224687)
9. FE Wilkinson C Kim NM Cho, et al. 1996 Isolation and identification of a protein with capsaicin-inhibited NADH oxidase activity from culture media conditioned by growth of HeLa cells Arch Biochem Biophys 336 275 282 8954575 10.1006/abbi.1996.0558 1:CAS:528:DyaK2sXnt1Sr (Pubitemid 26428242)
10. DJ Morre S Caldwell A Mayorga L-Y Wu DM Morré 1997 NADH oxidase activity from sera altered by capsaicin is widely distributed among cancer patients Arch Biochem Biophys 342 224 230 9186482 10.1006/abbi.1997.0110 1:CAS:528:DyaK2sXjvVWit7k%3D (Pubitemid 27251242)
11. DJ Morre T Reust 1997 A circulating form of NADH oxidase activity responsive to the antitumor sulfonylurea N-4-(methylphenylsulfonyl)-N'-(4- chlorophenyl)urea (LYl8l984) specific to sera of cancer patients J Bioenerg Biomemb 29 281 289 10.1023/A:1022466212083 1:CAS:528:DyaK2sXlslyku7o%3D (Pubitemid 27371729)
12. NM Cho PJ Chueh C Kim S Caldwell DM Morré DJ Morré 2002 Monoclonal antibody to a cancer-specific and drug-responsive hydroquinone (NADH) oxidase from sera of cancer patients Cancer Immunol Immunother 51 121 129 11941450 10.1007/s00262-001-0262-2 1:CAS:528:DC%2BD38XksVCqu70%3D (Pubitemid 34298107)
13. X Tang Z Tian PJ Chueh S Chen DM Morré DJ Morré 2007 Alternative splicing as the basis for specific localization of tNOX, a unique hydroquinone (NADH) oxidase, to the cancer cell surface Biochemistry 46 12337 12346 17924659 10.1021/bi700973k 1:CAS:528:DC%2BD2sXhtFaqsLzL (Pubitemid 350022388)
14. JS Huston M Mudgett-Hunter MS Tai J McCartney F Warren E Haber 1991 Protein engineering of single-chain Fv analogs and fusion proteins Methods Enzymol 203 46 88 1762568 10.1016/0076-6879(91)03005-2 1:CAS:528: DyaK38Xkt1Cnt7g%3D
15. GT Davis WD Bedzyk EW Voss TW Jacobs 1991 Single chain antibody (SCA) encoding genes: one-step construction and expression in eukaryotic cells Bio/Technology 9 165 169 1367186 10.1038/nbt0291-165 1:STN:280: DyaK3M3lsVOhtw%3D%3D
16. ME Goldberg N Expert-Bezançon L Vuillard T Rabilloud 1996 Non-detergent sulphobetaines: a new class of molecules that facilitate in vitro protein renaturation Structure 1 21 27 1:CAS:528:DyaK28XktlKisbg%3D
17. G Sardana J Marshall EP Diamandis 2007 Discovery of candidate tumor markers for prostate cancer via proteomic analysis of cell culture-conditioned medium Clin Chem 53 429 437 17259234 10.1373/clinchem.2006.077370 1:CAS:528:DC%2BD2sXis1Wnsrk%3D (Pubitemid 46447939)
18. DJ Morre 1995 NADH oxidase activity of HeLa plasma membranes inhibited by the antitumor sulfonylurea N-(4-methylphenylsulfonyl)-N-(4-chlorophenyl)urea (LY181984) at an external site Biochim Biophys Acta 1240 201 208 8541291 10.1016/0005-2736(95)00199-9 (Pubitemid 26005548)
19. S Wang DM Morre DJ Morré 2003 Sera from cancer patients contain two oscillating ECTO-NOX activities with different period lengths Cancer Lett 190 135 141 12565167 10.1016/S0304-3835(02)00616-X 1:CAS:528: DC%2BD3sXmsV2ntA%3D%3D (Pubitemid 36136011)
20. F Yantiri DJ Morré K Yagiz, et al. 1998 Capsaicin-responsive NADH oxidase activities from urine of cancer patients Arch Biochem Biophys 358 336 342 9784248 10.1006/abbi.1998.0877 1:CAS:528:DyaK1cXmslyksLg%3D (Pubitemid 28480953)