A multicenter case-control study on screening of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in han chinese

Gynecologic and Obstetric Investigation

Volumn 77, Issue 4, 2014, Pages 224-230

  Shen, Yang ^a   Ren, Mu Lan ^a   Xu, Jie ^a   Xu, Qian ^b   Ding, Yi Qian ^c   Wu, Zhi Cong ^d   Zhang, Hai Bao ^e   Huang, Xian Xia ^f   Cai, Yun Lang ^a  

^a SOUTHEAST UNIVERSITY   (Bangladesh)

^b SOUTHEAST UNIVERSITY   (China)

^c Department of Obstetrics and Gynecology   (China)

^d First Hospital of Putian   (China)

^e Department of Ophthalmology   (China)

^f Laiwu People's Hospital   (China)

Author keywords

Case control study; Estrogen metabolizing enzymes; Single nucleotide polymorphisms; Uterine leiomyoma

Indexed keywords

CATECHOL METHYLTRANSFERASE; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; GENOMIC DNA; COMT PROTEIN, HUMAN; CYP1A1 PROTEIN, HUMAN; CYP1B1 PROTEIN, HUMAN; GENETIC MARKER; TUMOR MARKER; ALANINE; ASPARTIC ACID; ENZYME; ESTROGEN METABOLIZING ENZYME; GLYCINE; ISOLEUCINE; METHIONINE; SERINE; UNCLASSIFIED DRUG; VALINE;

ADULT; ARTICLE; CARCINOGENESIS; CASE CONTROL STUDY; CONTROLLED STUDY; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA SEQUENCE; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC RISK; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENOTYPE; HAN CHINESE; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; UTERUS MYOMA; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CLINICAL TRIAL; ETHNOLOGY; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; LEIOMYOMA; MIDDLE AGED; MULTIVARIATE ANALYSIS; RISK FACTOR; STATISTICAL MODEL; UTERUS CANCER; COMT GENE; CYP1A1 GENE; CYP1B1 GENE; GENE;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CATECHOL O-METHYLTRANSFERASE; CHINA; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1B1; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LEIOMYOMA; LOGISTIC MODELS; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SEQUENCE ANALYSIS, DNA; TUMOR MARKERS, BIOLOGICAL; UTERINE NEOPLASMS;

EID: 84903715239     PISSN: 03787346     EISSN: 1423002X     Source Type: Journal    
DOI: 10.1159/000360083     Document Type: Article

References (26)

1. Duhan N, Sirohiwal D: Uterine myomas revisited. Eur J Obstet Gynecol Reprod Biol 2010; 152:119-125.
2. Shen Y, Xu Q, Xu J, Ren ML, Cai YL: Environmental exposure and risk of uterine leiomyo-ma: an epidemiologic survey. Euro Rev Med Pharmacol Sci 2013; 17:3249-3256.
3. Grings AO, Lora V, Ferreira GD, Brum IS, Corleta HV, Capp E: Protein expression of estrogen receptors α and β and aromatase in myometrium and uterine leiomyoma. Gyne-col Obstet Invest 2012; 73:113-117.
4. Walker CL, Stewart EA: Uterine fibroids: the elephant in the room. Science 2005; 308:1589-1592. (Pubitemid 40807499)
5. Shen Y, Xu Q, Ren M, Feng X, Cai Y, Gao Y: Measurement of phenolic environmental estrogens in women with uterine leiomyoma. PLoS One 2013; 8:e79838.
6. Maruo T, Ohara N, Wang J, Matsuo H: Sex steroidal regulation of uterine leiomyoma growth and apoptosis. Hum Reprod Update 2004; 10:207-220. (Pubitemid 38750141)
7. Othman EE, Al-Hendy A: Molecular genetics and racial disparities of uterine leiomyomas. Best Pract Res Clin Obstet Gynaecol 2008; 22: 589-601. (Pubitemid 351804123)
8. Tsuchiya Y, Nakajima M, Yokoi T: Cyto-chrome P450-mediated metabolism of estrogens and its regulation in human. Cancer Lett 2005; 227:115-124. (Pubitemid 41174580)
9. Gajjar K, Martin-Hirsch PL, Martin FL: CYP1B1 and hormone-induced cancer. Cancer Lett 2012; 324:13-30.
10. Duhan N, Sirohiwal D: Uterine myomas revisited. Eur J Obstet Gynecol Reprod Biol 2010; 152:119-125.
11. Mitrunen K, Hirvonen A: Molecular epidemiology of sporadic breast cancer: the role of polymorphic genes involved in oestrogen biosynthesis and metabolism. Mutat Res 2003; 544:9-41. (Pubitemid 36903202)
12. Yager JD, Liehr JG: Molecular mechanisms of estrogen carcinogenesis. Annu Rev Pharmacol Toxicol 1996; 36:203-232. (Pubitemid 26168699)
13. Tunbridge EM: The catechol-O-methyltrans-ferase gene: its regulation and polymorphisms. Int Rev Neurobiol 2010; 95:7-27.
14. Illi A, Setälä-Soikkeli E, Kampman O, et al: Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder. Psychiatry Res 2010; 176:85-87.
15. De Oliveira E, de Aquino Castro R, Gomes MT, et al: The catechol-O-methyltransferase (COMT) gene polymorphism and prevalence of uterine fibroids. Maturitas 2008; 60:235-238.
16. Gooden KM, Schroeder JC, North KE, et al: Val153Met polymorphism of catechol-O-methyltransferase and prevalence of uterine leiomyomata. Reprod Sci 2007; 14:117-120. (Pubitemid 351168836)
17. Mao C, Wang XW, Qiu LX: Lack of association between catechol-O- methyltransferase Val108/158Met polymorphism and breast cancer risk: a meta-analysis of 25, 627 cases and 34, 222 controls. Breast Cancer Res Treat 2010; 121:719-725.
18. EI-Shennawy GA, Elbialy AA, Isamil AE, EI Behery MM: Is genetic polymorphism of ER-α, CYP1A1, and CYP1B1 a risk factor for uterine leiomyoma? Arch Gynecol Obstet 2011; 283:1313-1318.
19. Barão MA, Oliveira E, Gomes MT, et al: The role of MSP I CYP1A1 gene polymorphism in the development of uterine fibroids. Fertil Steril 2010; 94:2783-2785.
20. Sowers MR, Wilson AL, Kardia SR, Chu J, McConnell DS: CYP1A1 and CYP1B1 polymorphisms and their association with estra-diol and estrogen metabolites in women who are premenopausal and perimenopausal. Am J Med 2006; 119(suppl 1):S44-S51. (Pubitemid 44292102)
21. Ye Y, Cheng X, Luo HB, Liu L, Li YB, Hou YP: CYP1A1 and CYP1B1 genetic polymorphisms and uterine leiomyoma risk in Chinese women. J Assist Reprod Genet 2008; 25: 389-394.
22. Bruno RD, Njar VC: Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development. Bioorg Med Chem 2007; 15:5047-5060. (Pubitemid 46880385)
23. Helmig S, Seelinger JU, Philipp-Gehlhaar M, Döhrel J, Schneider J: Cyp1B1 mRNA expression in correlation to cotinine levels with respect to the Cyp1B1 L432V gene polymorphism. Eur J Epidemiol 2010; 25:867-873.
24. Cui L, Dillehay K, Chen W, Shen D, Dong Z, Li W: Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: a meta-analysis. Mol Biol Rep 2012; 39: 7465-7471.
25. Xu W, Zhou Y, Hang X, Shen D: Current evidence on the relationship between CYP1B1 polymorphisms and lung cancer risk: a meta-analysis. Mol Biol Rep 2012; 39:2821-2829.
26. Chen B, Qiu LX, Li Y, Xu W, Wang XL, Zhao WH, Wu JQ: The CYP1B1 Leu432Val polymorphism contributes to lung cancer risk: evidence from 6, 501 subjects. Lung Cancer 2010; 70:247-252.