-
1
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden, K. H. & Prives, C. Blinded by the Light: The Growing Complexity of p53. Cell 137, 413-31 (2009).
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
2
-
-
77249176666
-
P53 and stem cells: New developments and new concerns
-
Zhao, T. & Xu, Y. p53 and stem cells: new developments and new concerns. Trends Cell Biol 20, 170-5 (2010).
-
(2010)
Trends Cell Biol
, vol.20
, pp. 170-175
-
-
Zhao, T.1
Xu, Y.2
-
3
-
-
65549120715
-
Modes of p53 regulation
-
Kruse, J. P. & Gu, W. Modes of p53 regulation. Cell 137, 609-22 (2009).
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
4
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans, M. J. & Kaufman, M. H. Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-6 (1981).
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
5
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin, G. R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 78, 7634-8 (1981).
-
(1981)
Proc Natl Acad Sci U S A
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
6
-
-
0024245022
-
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
-
Smith, A. G. et al. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336, 688-90 (1988).
-
(1988)
Nature
, vol.336
, pp. 688-690
-
-
Smith, A.G.1
-
7
-
-
0021358883
-
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
-
Bradley, A., Evans, M., Kaufman, M. H. & Robertson, E. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309, 255-6 (1984).
-
(1984)
Nature
, vol.309
, pp. 255-256
-
-
Bradley, A.1
Evans, M.2
Kaufman, M.H.3
Robertson, E.4
-
8
-
-
67650261871
-
Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage
-
Solozobova, V., Rolletschek, A. & Blattner, C. Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage. BMC Cell Biol 10, 46 (2009).
-
(2009)
BMC Cell Biol
, vol.10
, pp. 46
-
-
Solozobova, V.1
Rolletschek, A.2
Blattner, C.3
-
9
-
-
77955052580
-
Regulation of p53 in embryonic stem cells
-
Solozobova, V. & Blattner, C. Regulation of p53 in embryonic stem cells. Exp Cell Res 316, 2434-46 (2010).
-
(2010)
Exp Cell Res
, vol.316
, pp. 2434-2446
-
-
Solozobova, V.1
Blattner, C.2
-
10
-
-
13944273471
-
P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
-
Lin, T. et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 7, 165-71 (2005).
-
(2005)
Nat Cell Biol
, vol.7
, pp. 165-171
-
-
Lin, T.1
-
11
-
-
39749087530
-
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
-
Han, M. K. et al. SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2, 241-51 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, pp. 241-251
-
-
Han, M.K.1
-
12
-
-
78049423721
-
Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs
-
Ungewitter, E. & Scrable, H. Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs. Genes Dev 24, 2408-19 (2010).
-
(2010)
Genes Dev
, vol.24
, pp. 2408-2419
-
-
Ungewitter, E.1
Scrable, H.2
-
13
-
-
84864631288
-
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling
-
Lee, D. F. et al. Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell 11, 179-94 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 179-194
-
-
Lee, D.F.1
-
14
-
-
0032576768
-
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
-
Aladjem, M. I. et al. ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage. Curr Biol 8, 145-55 (1998).
-
(1998)
Curr Biol
, vol.8
, pp. 145-155
-
-
Aladjem, M.I.1
-
15
-
-
0028157458
-
Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts
-
Savatier, P., Huang, S., Szekely, L., Wiman, K. G. & Samarut, J. Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts. Oncogene 9, 809-18 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 809-818
-
-
Savatier, P.1
Huang, S.2
Szekely, L.3
Wiman, K.G.4
Samarut, J.5
-
16
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower, L. A. et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356, 215-21 (1992).
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
-
17
-
-
0032127977
-
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
-
Niwa, H., Burdon, T., Chambers, I. & Smith, A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 12, 2048-60 (1998).
-
(1998)
Genes Dev
, vol.12
, pp. 2048-2060
-
-
Niwa, H.1
Burdon, T.2
Chambers, I.3
Smith, A.4
-
18
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda, K. et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci U S A 94, 3801-4 (1997).
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
-
19
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Ying, Q. L. et al. The ground state of embryonic stem cell self-renewal. Nature 453, 519-23 (2008).
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
-
20
-
-
42149192008
-
Identification and characterization of subpopulations in undifferentiated ES cell culture
-
Toyooka, Y., Shimosato, D., Murakami, K., Takahashi, K. & Niwa, H. Identification and characterization of subpopulations in undifferentiated ES cell culture. Development 135, 909-18 (2008).
-
(2008)
Development
, vol.135
, pp. 909-918
-
-
Toyooka, Y.1
Shimosato, D.2
Murakami, K.3
Takahashi, K.4
Niwa, H.5
-
21
-
-
84874091860
-
Transcription factor network in embryonic stem cells: Heterogeneity under the stringency
-
Nakai-Futatsugi, Y. & Niwa, H. Transcription Factor Network in Embryonic Stem Cells: Heterogeneity under the Stringency. Biol Pharm Bull 36, 166-70 (2013).
-
(2013)
Biol Pharm Bull
, vol.36
, pp. 166-170
-
-
Nakai-Futatsugi, Y.1
Niwa, H.2
-
22
-
-
0025054992
-
Expression pattern of the mouse T gene and its role in mesoderm formation
-
Wilkinson, D. G., Bhatt, S. & Herrmann, B. G. Expression pattern of the mouse T gene and its role in mesoderm formation. Nature 343, 657-9 (1990).
-
(1990)
Nature
, vol.343
, pp. 657-659
-
-
Wilkinson, D.G.1
Bhatt, S.2
Herrmann, B.G.3
-
23
-
-
1542285168
-
PML is a direct p53 target that modulates p53 effector functions
-
de Stanchina, E. et al. PML is a direct p53 target that modulates p53 effector functions. Mol Cell 13, 523-35 (2004).
-
(2004)
Mol Cell
, vol.13
, pp. 523-535
-
-
De Stanchina, E.1
-
24
-
-
0025992469
-
Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
-
Friedrich, G. & Soriano, P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5, 1513-23 (1991).
-
(1991)
Genes Dev
, vol.5
, pp. 1513-1523
-
-
Friedrich, G.1
Soriano, P.2
-
25
-
-
0030034110
-
Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor upregulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells
-
Savatier, P., Lapillonne, H., van Grunsven, L. A., Rudkin, B. B. & Samarut, J. Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor upregulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene 12, 309-22 (1996).
-
(1996)
Oncogene
, vol.12
, pp. 309-322
-
-
Savatier, P.1
Lapillonne, H.2
Van Grunsven, L.A.3
Rudkin, B.B.4
Samarut, J.5
-
26
-
-
38849199681
-
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
-
Sakaue-Sawano, A. et al. Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell 132, 487-98 (2008).
-
(2008)
Cell
, vol.132
, pp. 487-498
-
-
Sakaue-Sawano, A.1
-
27
-
-
0032821417
-
Mml, a mouse Mix-like gene expressed in the primitive streak
-
Pearce, J. J. & Evans, M. J. Mml, a mouse Mix-like gene expressed in the primitive streak. Mech Dev 87, 189-92 (1999).
-
(1999)
Mech Dev
, vol.87
, pp. 189-192
-
-
Pearce, J.J.1
Evans, M.J.2
-
28
-
-
0026649645
-
Gastrulation in the mouse: The role of the homeobox gene goosecoid
-
Blum, M. et al. Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell 26, 1097-106 (1992).
-
(1992)
Cell
, vol.26
, pp. 1097-1106
-
-
Blum, M.1
-
29
-
-
0028103739
-
Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis
-
Barnes, J. D., Crosby, J. L., Jones, C. M., Wright, C. V. & Hogan, B. L. Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis. Dev Biol 161, 168-78 (1994).
-
(1994)
Dev Biol
, vol.161
, pp. 168-178
-
-
Barnes, J.D.1
Crosby, J.L.2
Jones, C.M.3
Wright, C.V.4
Hogan, B.L.5
-
30
-
-
0030578421
-
GATA-6: A zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm
-
Morrisey, E. E., Ip, H. S., Lu, M. M. & Parmacek, M. S. GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm. Dev Biol 177, 309-22 (1996).
-
(1996)
Dev Biol
, vol.177
, pp. 309-322
-
-
Morrisey, E.E.1
Ip, H.S.2
Lu, M.M.3
Parmacek, M.S.4
-
31
-
-
0025843564
-
mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation
-
Hebert, J. M., Boyle, M. & Martin, G. R. mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation. Development 112, 407-15 (1991).
-
(1991)
Development
, vol.112
, pp. 407-415
-
-
Hebert, J.M.1
Boyle, M.2
Martin, G.R.3
-
32
-
-
0021891053
-
The in vitro development of blastocyst-derived embryonic stem cell lines: Formation of visceral yolk sac, blood islands and myocardium
-
Doetschman, T. C., Eistetter, H., Katz, M., Schmidt, W. & Kemler, R. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol 87, 27-45 (1985).
-
(1985)
J Embryol Exp Morphol
, vol.87
, pp. 27-45
-
-
Doetschman, T.C.1
Eistetter, H.2
Katz, M.3
Schmidt, W.4
Kemler, R.5
-
33
-
-
65549115574
-
Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse
-
Rossant, J. & Tam, P. P. Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse. Development 136, 701-13 (2009).
-
(2009)
Development
, vol.136
, pp. 701-713
-
-
Rossant, J.1
Tam, P.P.2
-
35
-
-
33947308285
-
How is pluripotency determined and maintained?
-
Niwa, H. How is pluripotency determined and maintained? Development 134, 635-46 (2007).
-
(2007)
Development
, vol.134
, pp. 635-646
-
-
Niwa, H.1
-
36
-
-
77950243286
-
Mouse ES cell culture system as a model of development
-
Niwa, H. Mouse ES cell culture system as a model of development. Dev Growth Differ 52, 275-83 (2010).
-
(2010)
Dev Growth Differ
, vol.52
, pp. 275-283
-
-
Niwa, H.1
-
37
-
-
0031833476
-
Progressive lineage analysis by cell sorting and culture identifies FLK1 + VEcadherin + cells at a diverging point of endothelial and hemopoietic lineages
-
Nishikawa, S. I., Nishikawa, S., Hirashima, M., Matsuyoshi, N. & Kodama, H. Progressive lineage analysis by cell sorting and culture identifies FLK1 + VEcadherin + cells at a diverging point of endothelial and hemopoietic lineages. Development 125, 1747-57 (1998).
-
(1998)
Development
, vol.125
, pp. 1747-1757
-
-
Nishikawa, S.I.1
Nishikawa, S.2
Hirashima, M.3
Matsuyoshi, N.4
Kodama, H.5
-
38
-
-
0037313844
-
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
-
Ying, Q. L., Stavridis, M., Griffiths, D., Li, M. & Smith, A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 21, 183-6 (2003).
-
(2003)
Nat Biotechnol
, vol.21
, pp. 183-186
-
-
Ying, Q.L.1
Stavridis, M.2
Griffiths, D.3
Li, M.4
Smith, A.5
-
39
-
-
58149308288
-
Cyclosporin-A potently induces highly cardiogenic progenitors from embryonic stem cells
-
Yan, P. et al. Cyclosporin-A potently induces highly cardiogenic progenitors from embryonic stem cells. Biochem Biophys Res Commun 379, 115-20 (2009).
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 115-120
-
-
Yan, P.1
-
40
-
-
84870979058
-
OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells
-
Navarro, P. et al. OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells. Embo J 31, 4547-62 (2012).
-
(2012)
Embo J
, vol.31
, pp. 4547-4562
-
-
Navarro, P.1
-
41
-
-
34547737480
-
P73 suppresses polyploidy and aneuploidy in the absence of functional p53
-
Talos, F., Nemajerova, A., Flores, E. R., Petrenko, O. & Moll, U. M. p73 suppresses polyploidy and aneuploidy in the absence of functional p53. Mol Cell 27, 647-59 (2007).
-
(2007)
Mol Cell
, vol.27
, pp. 647-659
-
-
Talos, F.1
Nemajerova, A.2
Flores, E.R.3
Petrenko, O.4
Moll, U.M.5
-
42
-
-
84866481217
-
E-cadherin promotes incorporation of mouse epiblast stem cells into normal development
-
Ohtsuka, S., Nishikawa-Torikai, S. & Niwa, H. E-cadherin promotes incorporation of mouse epiblast stem cells into normal development. PLoS One 7, e45220 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e45220
-
-
Ohtsuka, S.1
Nishikawa-Torikai, S.2
Niwa, H.3
|