-
1
-
-
36148961543
-
Road to precision: Recombinase-based targeting technologies for genome engineering
-
Wirth, D., Gama-Norton, L., Riemer, P., Sandhu, U., Schucht, R., & Hauser, H. (2007). Road to precision: recombinase-based targeting technologies for genome engineering. Current Opinion in Biotechnology, 18, 411-419.
-
(2007)
Current Opinion in Biotechnology
, vol.18
, pp. 411-419
-
-
Wirth, D.1
Gama-Norton, L.2
Riemer, P.3
Sandhu, U.4
Schucht, R.5
Hauser, H.6
-
2
-
-
0035667397
-
The ons and offs of inducible transgenic technology: A review
-
Yamamoto, A., Hen, R., & Dauer, W. T. (2001). The ons and offs of inducible transgenic technology: a review. Neurobiology of Disease, 8, 923-932.
-
(2001)
Neurobiology of Disease
, vol.8
, pp. 923-932
-
-
Yamamoto, A.1
Hen, R.2
Dauer, W.T.3
-
3
-
-
32344453096
-
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells
-
Beard, C., Hochedlinger, K., Plath, K., Wutz, A., & Jaenisch, R. (2006). Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis, 44, 23-28.
-
(2006)
Genesis
, vol.44
, pp. 23-28
-
-
Beard, C.1
Hochedlinger, K.2
Plath, K.3
Wutz, A.4
Jaenisch, R.5
-
4
-
-
75049083784
-
Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones
-
Maes, C., Goossens, S., Bartunkova, S., et al. (2010). Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO Journal, 29, 424-441.
-
(2010)
EMBO Journal
, vol.29
, pp. 424-441
-
-
Maes, C.1
Goossens, S.2
Bartunkova, S.3
-
5
-
-
26444545103
-
Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction
-
Belteki, G., Haigh, J., Kabacs, N., et al. (2005). Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Research, 33, e51.
-
(2005)
Nucleic Acids Research
, vol.33
-
-
Belteki, G.1
Haigh, J.2
Kabacs, N.3
-
6
-
-
28544434189
-
An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo
-
Mao, J., Barrow, J., McMahon, J., Vaughan, J., & McMahon, A. P. (2005). An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo. Nucleic Acids Research, 33, e155.
-
(2005)
Nucleic Acids Research
, vol.33
-
-
Mao, J.1
Barrow, J.2
McMahon, J.3
Vaughan, J.4
McMahon, A.P.5
-
7
-
-
20844455934
-
Development of a unique system for spatiotemporal and lineagespecific gene expression in mice
-
Yu, H. M., Liu, B., Chiu, S. Y., Costantini, F., & Hsu, W. (2005). Development of a unique system for spatiotemporal and lineagespecific gene expression in mice. Proceedings of the National Academy of Sciences of the United States of America, 102, 8615-8620.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 8615-8620
-
-
Yu, H.M.1
Liu, B.2
Chiu, S.Y.3
Costantini, F.4
Hsu, W.5
-
8
-
-
65549111799
-
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells
-
Nyabi, O., Naessens, M., Haigh, K., et al. (2009). Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells. Nucleic Acids Research, 37, e55.
-
(2009)
Nucleic Acids Research
, vol.37
-
-
Nyabi, O.1
Naessens, M.2
Haigh, K.3
-
9
-
-
34547629188
-
Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference
-
Hitz, C., Wurst, W., & Kuhn, R. (2007). Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference. Nucleic Acids Research, 35, e90.
-
(2007)
Nucleic Acids Research
, vol.35
-
-
Hitz, C.1
Wurst, W.2
Kuhn, R.3
-
10
-
-
77956339881
-
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
-
Medina, P. P., Nolde, M., & Slack, F. J. (2010). OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature, 467, 86-90.
-
(2010)
Nature
, vol.467
, pp. 86-90
-
-
Medina, P.P.1
Nolde, M.2
Slack, F.J.3
-
11
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano, P. (1999). Generalized lacZ expression with the ROSA26 Cre reporter strain. Nature Genetics, 21, 70-71.
-
(1999)
Nature Genetics
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
12
-
-
34447536153
-
Gateway(R) recombinational cloning: A biological operating system
-
Katzen, F. (2007). Gateway(R) recombinational cloning: a biological operating system. Expert Opinion Drug Discovery, 2, 571-589.
-
(2007)
Expert Opinion Drug Discovery
, vol.2
, pp. 571-589
-
-
Katzen, F.1
-
13
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K., & Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
14
-
-
84874230562
-
The ROSA26-iPSC mouse: A conditional, inducible, and exchangeable resource for studying cellular (De)Differentiation
-
Haenebalcke, L., Goossens, S., Dierickx, P., et al. (2013). The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)Differentiation. Cell Rep, 3, 335-341.
-
(2013)
Cell Rep
, vol.3
, pp. 335-341
-
-
Haenebalcke, L.1
Goossens, S.2
Dierickx, P.3
-
15
-
-
78651322759
-
Strict control of transgene expression in a mouse model for sensitive biological applications based on RMCE compatible ES cells
-
Sandhu, U., Cebula, M., Behme, S., et al. (2011). Strict control of transgene expression in a mouse model for sensitive biological applications based on RMCE compatible ES cells. Nucleic Acids Research, 39, e1.
-
(2011)
Nucleic Acids Research
, vol.39
-
-
Sandhu, U.1
Cebula, M.2
Behme, S.3
-
16
-
-
34249850644
-
Reversible gene knockdown in mice using a tight, inducible shRNA expression system
-
Seibler, J., Kleinridders, A., Kuter-Luks, B., Niehaves, S., Bruning, J. C., & Schwenk, F. (2007). Reversible gene knockdown in mice using a tight, inducible shRNA expression system. Nucleic Acids Research, 35, e54.
-
(2007)
Nucleic Acids Research
, vol.35
-
-
Seibler, J.1
Kleinridders, A.2
Kuter-Luks, B.3
Niehaves, S.4
Bruning, J.C.5
Schwenk, F.6
-
17
-
-
77954009587
-
Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps
-
Schebelle, L., Wolf, C., Stribl, C., et al. (2010). Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps. Nucleic Acids Research, 38, e106.
-
(2010)
Nucleic Acids Research
, vol.38
-
-
Schebelle, L.1
Wolf, C.2
Stribl, C.3
-
18
-
-
35548970476
-
Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent
-
Strathdee, D., Ibbotson, H., & Grant, S. G. (2006). Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent. PLoS One, 1, e4.
-
(2006)
PLoS One
, vol.1
-
-
Strathdee, D.1
Ibbotson, H.2
Grant, S.G.3
-
19
-
-
62849100430
-
Aberrant epigenetic silencing is triggered by a transient reduction in gene expression
-
Oyer, J. A., Chu, A., Brar, S., & Turker, M. S. (2009). Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. PLoS One, 4, e4832.
-
(2009)
PLoS One
, vol.4
-
-
Oyer, J.A.1
Chu, A.2
Brar, S.3
Turker, M.S.4
-
20
-
-
80051613693
-
A comparison of exogenous promoter activity at the ROSA26 locus using a PhiC31 integrase mediated cassette exchange approach in mouse ES cells
-
Chen, C. M., Krohn, J., Bhattacharya, S., & Davies, B. (2011). A comparison of exogenous promoter activity at the ROSA26 locus using a PhiC31 integrase mediated cassette exchange approach in mouse ES cells. PLoS One, 6, e23376.
-
(2011)
PLoS One
, vol.6
-
-
Chen, C.M.1
Krohn, J.2
Bhattacharya, S.3
Davies, B.4
-
21
-
-
0036216990
-
Analysis of different promoter systems for efficient transgene expression in mouse embryonic stem cell lines
-
Dayton, Ohio
-
Chung, S., Andersson, T., Sonntag, K. C., Bjorklund, L., Isacson, O., & Kim, K. S. (2002). Analysis of different promoter systems for efficient transgene expression in mouse embryonic stem cell lines. Stem Cells, 20, 139-145. Dayton, Ohio.
-
(2002)
Stem Cells
, vol.20
, pp. 139-145
-
-
Chung, S.1
Andersson, T.2
Sonntag, K.C.3
Bjorklund, L.4
Isacson, O.5
Kim, K.S.6
-
22
-
-
33744780724
-
CMV promotor activity during ES cell differentiation: Potential insight into embryonic stem cell differentiation
-
Bagchi, B., Kumar, M., & Mani, S. (2006). CMV promotor activity during ES cell differentiation: potential insight into embryonic stem cell differentiation. Cell Biology International, 30, 505-513.
-
(2006)
Cell Biology International
, vol.30
, pp. 505-513
-
-
Bagchi, B.1
Kumar, M.2
Mani, S.3
-
23
-
-
43049087055
-
Promoter-dependent EGFP expression during embryonic stem cell propagation and differentiation
-
Wang, R., Liang, J., Jiang, H., Qin, L. J., & Yang, H. T. (2008). Promoter-dependent EGFP expression during embryonic stem cell propagation and differentiation. Stem Cells and Development, 17, 279-289.
-
(2008)
Stem Cells and Development
, vol.17
, pp. 279-289
-
-
Wang, R.1
Liang, J.2
Jiang, H.3
Qin, L.J.4
Yang, H.T.5
-
24
-
-
84855855098
-
A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters
-
Tchorz, J. S., Suply, T., Ksiazek, I., et al. (2012). A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters. PLoS One, 7, e30011.
-
(2012)
PLoS One
, vol.7
-
-
Tchorz, J.S.1
Suply, T.2
Ksiazek, I.3
-
25
-
-
34447132528
-
Silencing and unsilencing of tetracycline-controlled genes in neurons
-
Zhu, P., Aller, M. I., Baron, U., et al. (2007). Silencing and unsilencing of tetracycline-controlled genes in neurons. PLoS One, 2, e533.
-
(2007)
PLoS One
, vol.2
-
-
Zhu, P.1
Aller, M.I.2
Baron, U.3
-
26
-
-
56949090665
-
Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice
-
Mehta, A. K., Majumdar, S. S., Alam, P., Gulati, N., & Brahmachari, V. (2009). Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice. Gene, 428, 20-24.
-
(2009)
Gene
, vol.428
, pp. 20-24
-
-
Mehta, A.K.1
Majumdar, S.S.2
Alam, P.3
Gulati, N.4
Brahmachari, V.5
-
27
-
-
0032530174
-
Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
-
Pikaart, M. J., Recillas-Targa, F., & Felsenfeld, G. (1998). Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators. Genes & Development, 12, 2852-2862.
-
(1998)
Genes & Development
, vol.12
, pp. 2852-2862
-
-
Pikaart, M.J.1
Recillas-Targa, F.2
Felsenfeld, G.3
-
28
-
-
0030965628
-
Ligand-inducible and liver-specific target gene expression in transgenic mice
-
Wang, Y., DeMayo, F. J., Tsai, S. Y., & O'Malley, B. W. (1997). Ligand-inducible and liver-specific target gene expression in transgenic mice. Nature Biotechnology, 15, 239-243.
-
(1997)
Nature Biotechnology
, vol.15
, pp. 239-243
-
-
Wang, Y.1
DeMayo, F.J.2
Tsai, S.Y.3
O'Malley, B.W.4
-
29
-
-
33745622131
-
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
-
Ciavatta, D., Kalantry, S., Magnuson, T., & Smithies, O. (2006). A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation. Proceedings of the National Academy of Sciences of the United States of America, 103, 9958-9963.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 9958-9963
-
-
Ciavatta, D.1
Kalantry, S.2
Magnuson, T.3
Smithies, O.4
-
30
-
-
0037024370
-
Insulators prevent transcriptional interference between two promoters in a double gene construct for transgenesis
-
Hasegawa, K., & Nakatsuji, N. (2002). Insulators prevent transcriptional interference between two promoters in a double gene construct for transgenesis. FEBS Letters, 520, 47-52.
-
(2002)
FEBS Letters
, vol.520
, pp. 47-52
-
-
Hasegawa, K.1
Nakatsuji, N.2
-
31
-
-
34248366984
-
Developmental and adult phenotyping directly from mutant embryonic stem cells
-
George, S. H., Gertsenstein, M., Vintersten, K., et al. (2007). Developmental and adult phenotyping directly from mutant embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America, 104, 4455-4460.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 4455-4460
-
-
George, S.H.1
Gertsenstein, M.2
Vintersten, K.3
-
32
-
-
0034488835
-
Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision
-
Novak, A., Guo, C., Yang, W., Nagy, A., & Lobe, C. G. (2000). Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis, 28, 147-155.
-
(2000)
Genesis
, vol.28
, pp. 147-155
-
-
Novak, A.1
Guo, C.2
Yang, W.3
Nagy, A.4
Lobe, C.G.5
-
33
-
-
0028109636
-
Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci
-
Schlake, T., & Bode, J. (1994). Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci. Biochemistry, 33, 12746-12751.
-
(1994)
Biochemistry
, vol.33
, pp. 12746-12751
-
-
Schlake, T.1
Bode, J.2
-
34
-
-
46749110736
-
Chicken beta-globin insulator overcomes variegation of transgenes in Xenopus embryos
-
Sekkali, B., Tran, H. T., Crabbe, E., De Beule, C., Van Roy, F., & Vleminckx, K. (2008). Chicken beta-globin insulator overcomes variegation of transgenes in Xenopus embryos. The FASEB Journal, 22, 2534-2540.
-
(2008)
The FASEB Journal
, vol.22
, pp. 2534-2540
-
-
Sekkali, B.1
Tran, H.T.2
Crabbe, E.3
De Beule, C.4
Van Roy, F.5
Vleminckx, K.6
-
35
-
-
78650681563
-
Mesp1: A key regulator of cardiovascular lineage commitment
-
Bondue, A., & Blanpain, C. (2010). Mesp1: a key regulator of cardiovascular lineage commitment. Circulation Research, 107, 1414-1427.
-
(2010)
Circulation Research
, vol.107
, pp. 1414-1427
-
-
Bondue, A.1
Blanpain, C.2
-
36
-
-
74749086258
-
Recombinant protein expression by targeting pre-selected chromosomal loci
-
Nehlsen, K., Schucht, R., da Gama-Norton, L., et al. (2009). Recombinant protein expression by targeting pre-selected chromosomal loci. BMC Biotechnology, 9, 100.
-
(2009)
BMC Biotechnology
, vol.9
, pp. 100
-
-
Nehlsen, K.1
Schucht, R.2
da Gama-Norton, L.3
-
37
-
-
33745668475
-
A new generation of retroviral producer cells: Predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors
-
Schucht, R., Coroadinha, A. S., Zanta-Boussif, M. A., et al. (2006). A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors. Molecular Therapy, 14, 285-292.
-
(2006)
Molecular Therapy
, vol.14
, pp. 285-292
-
-
Schucht, R.1
Coroadinha, A.S.2
Zanta-Boussif, M.A.3
-
38
-
-
84865537655
-
Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells
-
Pieters, T., Haenebalcke, L., Hochepied, T., et al. (2012). Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells. Stem Cell Reviews, 8, 768-778.
-
(2012)
Stem Cell Reviews
, vol.8
, pp. 768-778
-
-
Pieters, T.1
Haenebalcke, L.2
Hochepied, T.3
-
39
-
-
0033150591
-
Association of the 5′HS4 sequence of the chicken beta-globin locus control region with human EF1 alpha gene promoter induces ubiquitous and high expression of human CD55 and CD59 cDNAs in transgenic rabbits
-
Taboit-Dameron, F., Malassagne, B., Viglietta, C., et al. (1999). Association of the 5′HS4 sequence of the chicken beta-globin locus control region with human EF1 alpha gene promoter induces ubiquitous and high expression of human CD55 and CD59 cDNAs in transgenic rabbits. Transgenic Research, 8, 223-235.
-
(1999)
Transgenic Research
, vol.8
, pp. 223-235
-
-
Taboit-Dameron, F.1
Malassagne, B.2
Viglietta, C.3
-
40
-
-
79952696452
-
A rapid and scalable system for studying gene function in mice using conditional RNA interference
-
Premsrirut, P. K., Dow, L. E., Kim, S. Y., et al. (2011). A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell, 145, 145-158.
-
(2011)
Cell
, vol.145
, pp. 145-158
-
-
Premsrirut, P.K.1
Dow, L.E.2
Kim, S.Y.3
-
41
-
-
37249003928
-
Oncogene addiction: Setting the stage for molecularly targeted cancer therapy
-
Sharma, S. V., & Settleman, J. (2007). Oncogene addiction: setting the stage for molecularly targeted cancer therapy. Genes & Development, 21, 3214-3231.
-
(2007)
Genes & Development
, vol.21
, pp. 3214-3231
-
-
Sharma, S.V.1
Settleman, J.2
-
42
-
-
44849093562
-
Oncogene addiction
-
discussion 3080
-
Weinstein, I. B., & Joe, A. (2008). Oncogene addiction. Cancer Research, 68, 3077-3080. discussion 3080.
-
(2008)
Cancer Research
, vol.68
, pp. 3077-3080
-
-
Weinstein, I.B.1
Joe, A.2
-
43
-
-
84867331009
-
Bioluminescence based in vivo screening technologies
-
Kelkar, M., & De, A. (2012). Bioluminescence based in vivo screening technologies. Current Opinion in Pharmacology, 12, 592-600.
-
(2012)
Current Opinion in Pharmacology
, vol.12
, pp. 592-600
-
-
Kelkar, M.1
De, A.2
|