메뉴 건너뛰기




Volumn 68, Issue , 2014, Pages 48-59

The polyketide synthase gene pks4 is essential for sexual development and regulates fruiting body morphology in Sordaria macrospora

Author keywords

Fruiting body; Perithecium; Pks4; Polyketide synthase; Sordaria macrospora

Indexed keywords

METHYLTRANSFERASE; POLYKETIDE SYNTHASE; POLYKETIDE SYNTHASE 4; UNCLASSIFIED DRUG; FUNGAL PROTEIN;

EID: 84903635147     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2014.04.008     Document Type: Article
Times cited : (37)

References (62)
  • 3
    • 58149287683 scopus 로고    scopus 로고
    • In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites
    • Ansari M.Z., Sharma J., Gokhale R.S., Mohanty D. In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites. BMC Bioinf. 2008, 9:454.
    • (2008) BMC Bioinf. , vol.9 , pp. 454
    • Ansari, M.Z.1    Sharma, J.2    Gokhale, R.S.3    Mohanty, D.4
  • 7
    • 84871292787 scopus 로고    scopus 로고
    • Regulation of fungal secondary metabolism
    • Brakhage A.A. Regulation of fungal secondary metabolism. Nat. Rev. Microbiol. 2013, 11:21-32.
    • (2013) Nat. Rev. Microbiol. , vol.11 , pp. 21-32
    • Brakhage, A.A.1
  • 8
    • 78650198931 scopus 로고    scopus 로고
    • Fungal secondary metabolites - strategies to activate silent gene clusters
    • Brakhage A.A., Schroeckh V. Fungal secondary metabolites - strategies to activate silent gene clusters. Fungal Genet. Biol. 2011, 48:15-22.
    • (2011) Fungal Genet. Biol. , vol.48 , pp. 15-22
    • Brakhage, A.A.1    Schroeckh, V.2
  • 9
    • 0028330390 scopus 로고
    • Isolation and characterization of sexual spore pigments from Aspergillus nidulans
    • Brown D.W., Salvo J.J. Isolation and characterization of sexual spore pigments from Aspergillus nidulans. Appl. Environ. Microbiol. 1994, 60:979-983.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 979-983
    • Brown, D.W.1    Salvo, J.J.2
  • 10
    • 84863393769 scopus 로고    scopus 로고
    • Phylogenomic and functional domain analysis of polyketide synthases in Fusarium
    • Brown D.W., Butchko R.A.E., Baker S.E., Proctor R.H. Phylogenomic and functional domain analysis of polyketide synthases in Fusarium. Fungal Biol. 2012, 116:318-331.
    • (2012) Fungal Biol. , vol.116 , pp. 318-331
    • Brown, D.W.1    Butchko, R.A.E.2    Baker, S.E.3    Proctor, R.H.4
  • 13
    • 34250790717 scopus 로고    scopus 로고
    • Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets
    • Cox R.J. Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets. Org. Biomol. Chem. 2007, 5:2010-2026.
    • (2007) Org. Biomol. Chem. , vol.5 , pp. 2010-2026
    • Cox, R.J.1
  • 14
    • 3142615272 scopus 로고    scopus 로고
    • Validation of housekeeping genes for normalizing RNA expression in real-time PCR
    • Dheda K., Huggett J.F., Bustin S.A., Johnson M.A., Rook G., Zumla A. Validation of housekeeping genes for normalizing RNA expression in real-time PCR. Biotechniques 2004, 37:112-119.
    • (2004) Biotechniques , vol.37 , pp. 112-119
    • Dheda, K.1    Huggett, J.F.2    Bustin, S.A.3    Johnson, M.A.4    Rook, G.5    Zumla, A.6
  • 15
    • 34548570036 scopus 로고    scopus 로고
    • Regulation of melanin biosynthesis via the dihydroxynaphtalene pathway is dependent on sexual development in the ascomycete Sordaria macrospora
    • Engh I., Nowrousian M., Kück U. Regulation of melanin biosynthesis via the dihydroxynaphtalene pathway is dependent on sexual development in the ascomycete Sordaria macrospora. FEMS Microbiol. Lett. 2007, 275:62-70.
    • (2007) FEMS Microbiol. Lett. , vol.275 , pp. 62-70
    • Engh, I.1    Nowrousian, M.2    Kück, U.3
  • 17
    • 78149408002 scopus 로고    scopus 로고
    • Sordaria macrospora, a model organism to study fungal cellular development
    • Engh I., Nowrousian M., Kück U. Sordaria macrospora, a model organism to study fungal cellular development. Eur. J. Cell Biol. 2010, 89.
    • (2010) Eur. J. Cell Biol. , vol.89
    • Engh, I.1    Nowrousian, M.2    Kück, U.3
  • 18
    • 56949083532 scopus 로고    scopus 로고
    • Secondary metabolism: regulation and role in fungal biology
    • Fox E.M., Howlett B.J. Secondary metabolism: regulation and role in fungal biology. Curr. Opin. Microbiol. 2008, 11:481-487.
    • (2008) Curr. Opin. Microbiol. , vol.11 , pp. 481-487
    • Fox, E.M.1    Howlett, B.J.2
  • 19
    • 33644945871 scopus 로고    scopus 로고
    • Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae
    • Gaffoor I., Trail F. Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae. Appl. Environ. Microbiol. 2006, 72:1793-1799.
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 1793-1799
    • Gaffoor, I.1    Trail, F.2
  • 20
    • 27744459121 scopus 로고    scopus 로고
    • Functional analysis of the polyketide synthase genes in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum)
    • Gaffoor I., Brown D.W., Plattner R., Proctor R.H., Qi W., Trail F. Functional analysis of the polyketide synthase genes in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum). Eukaryot. Cell 2005, 4:1926-1933.
    • (2005) Eukaryot. Cell , vol.4 , pp. 1926-1933
    • Gaffoor, I.1    Brown, D.W.2    Plattner, R.3    Proctor, R.H.4    Qi, W.5    Trail, F.6
  • 22
    • 0002947377 scopus 로고
    • Isolation and characterization of null pigmented mutant in Aspergillus
    • Han Y.J., Han D.M. Isolation and characterization of null pigmented mutant in Aspergillus. Korean J. Genet. 1993, 15:1-10.
    • (1993) Korean J. Genet. , vol.15 , pp. 1-10
    • Han, Y.J.1    Han, D.M.2
  • 24
    • 77955346444 scopus 로고    scopus 로고
    • Two components of a velvet-like complex control hyphal morphogenesis, conidiophore development, and penicillin biosynthesis in Penicillium chrysogenum
    • Hoff B., Kamerewerd J., Sigl C., Mitterbauer R., Zadra I., Kürnsteiner H., Kück U. Two components of a velvet-like complex control hyphal morphogenesis, conidiophore development, and penicillin biosynthesis in Penicillium chrysogenum. Eukaryot. Cell 2010, 9:1236-1250.
    • (2010) Eukaryot. Cell , vol.9 , pp. 1236-1250
    • Hoff, B.1    Kamerewerd, J.2    Sigl, C.3    Mitterbauer, R.4    Zadra, I.5    Kürnsteiner, H.6    Kück, U.7
  • 25
    • 33947694781 scopus 로고    scopus 로고
    • Natural products of filamentous fungi: enzymes, genes, and their regulation
    • Hoffmeister D., Keller N.P. Natural products of filamentous fungi: enzymes, genes, and their regulation. Nat. Prod. Rep. 2007, 24:393-416.
    • (2007) Nat. Prod. Rep. , vol.24 , pp. 393-416
    • Hoffmeister, D.1    Keller, N.P.2
  • 27
    • 70349231218 scopus 로고    scopus 로고
    • Bioinformatic perspectives on NRPS/PKS megasynthases: advances and challenges
    • Jenke-Kodama H., Dittmann E. Bioinformatic perspectives on NRPS/PKS megasynthases: advances and challenges. Nat. Prod. Rep. 2009, 26:874-883.
    • (2009) Nat. Prod. Rep. , vol.26 , pp. 874-883
    • Jenke-Kodama, H.1    Dittmann, E.2
  • 29
    • 56049085382 scopus 로고    scopus 로고
    • Three alpha subunits of heterotrimeric G proteins and an adenylyl cyclase have distinct roles in fruiting body development in the homothallic fungus Sordaria macrospora
    • Kamerewerd J., Jansson M., Nowrousian M., Pöggeler S., Kück U. Three alpha subunits of heterotrimeric G proteins and an adenylyl cyclase have distinct roles in fruiting body development in the homothallic fungus Sordaria macrospora. Genetics 2008, 180:191-206.
    • (2008) Genetics , vol.180 , pp. 191-206
    • Kamerewerd, J.1    Jansson, M.2    Nowrousian, M.3    Pöggeler, S.4    Kück, U.5
  • 30
    • 0031079973 scopus 로고    scopus 로고
    • Metabolic pathway gene clusters in filamentous fungi
    • Keller N.P., Hohn T.M. Metabolic pathway gene clusters in filamentous fungi. Fungal Genet. Biol. 1997, 21:17-29.
    • (1997) Fungal Genet. Biol. , vol.21 , pp. 17-29
    • Keller, N.P.1    Hohn, T.M.2
  • 31
    • 30544434099 scopus 로고    scopus 로고
    • Fungal secondary metabolism - from biochemistry to genomics
    • Keller N.P., Turner G., Bennett J.W. Fungal secondary metabolism - from biochemistry to genomics. Nat. Rev. Microbiol. 2005, 3:937-947.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 937-947
    • Keller, N.P.1    Turner, G.2    Bennett, J.W.3
  • 32
    • 0038112130 scopus 로고    scopus 로고
    • The npgA/cfwA gene encodes a putative 4'-phosphopantetheinyl transferase which is essential for penicillin biosynthesis in Aspergillus nidulans
    • Keszenman-Pereyra D., Lawrence S., Twfieg M.E., Price J., Turner G. The npgA/cfwA gene encodes a putative 4'-phosphopantetheinyl transferase which is essential for penicillin biosynthesis in Aspergillus nidulans. Curr. Genet. 2003, 43:186-190.
    • (2003) Curr. Genet. , vol.43 , pp. 186-190
    • Keszenman-Pereyra, D.1    Lawrence, S.2    Twfieg, M.E.3    Price, J.4    Turner, G.5
  • 33
    • 77953758862 scopus 로고    scopus 로고
    • Functional characterization of MAT1-1-specific mating-type genes in the homothallic ascomycete Sordaria macrospora provides new insights into essential and non-essential sexual regulators
    • Klix V., Nowrousian M., Ringelberg C., Loros J.J., Dunlap J.C., Pöggeler S. Functional characterization of MAT1-1-specific mating-type genes in the homothallic ascomycete Sordaria macrospora provides new insights into essential and non-essential sexual regulators. Eukaryot. Cell 2010, 9:894-905.
    • (2010) Eukaryot. Cell , vol.9 , pp. 894-905
    • Klix, V.1    Nowrousian, M.2    Ringelberg, C.3    Loros, J.J.4    Dunlap, J.C.5    Pöggeler, S.6
  • 34
    • 0347994901 scopus 로고    scopus 로고
    • Phylogenomic analyis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes
    • Kroken S., Glass N.L., Taylor J.W., Yoder O.C., Turgeon B.G. Phylogenomic analyis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes. Proc. Natl. Acad. Sci. USA 2003, 100:15670-15675.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15670-15675
    • Kroken, S.1    Glass, N.L.2    Taylor, J.W.3    Yoder, O.C.4    Turgeon, B.G.5
  • 36
    • 0344348872 scopus 로고    scopus 로고
    • 6 zinc finger transcription factor required for fruiting body development
    • 6 zinc finger transcription factor required for fruiting body development. Genetics 1999, 152:191-199.
    • (1999) Genetics , vol.152 , pp. 191-199
    • Masloff, S.1    Pöggeler, S.2    Kück, U.3
  • 37
    • 33645221485 scopus 로고    scopus 로고
    • Pheromones and pheromone receptors are required for proper sexual development in the homothallic ascomycete Sordaria macrospora
    • Mayrhofer S., Weber J.M., Pöggeler S. Pheromones and pheromone receptors are required for proper sexual development in the homothallic ascomycete Sordaria macrospora. Genetics 2006, 172:1521-1533.
    • (2006) Genetics , vol.172 , pp. 1521-1533
    • Mayrhofer, S.1    Weber, J.M.2    Pöggeler, S.3
  • 38
    • 0037118621 scopus 로고    scopus 로고
    • Functional characterization of 4'-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5
    • Mootz H.D., Schörgendorfer K., Marahiel M.A. Functional characterization of 4'-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5. FEMS Microbiol. Lett. 2002, 213:51-57.
    • (2002) FEMS Microbiol. Lett. , vol.213 , pp. 51-57
    • Mootz, H.D.1    Schörgendorfer, K.2    Marahiel, M.A.3
  • 39
    • 67349142369 scopus 로고    scopus 로고
    • A novel polyketide biosynthesis gene cluster is involved in fruiting body morphogenesis in the filamentous fungi Sordaria macrospora and Neurospora crassa
    • Nowrousian M. A novel polyketide biosynthesis gene cluster is involved in fruiting body morphogenesis in the filamentous fungi Sordaria macrospora and Neurospora crassa. Curr. Genet. 2009, 55:185-198.
    • (2009) Curr. Genet. , vol.55 , pp. 185-198
    • Nowrousian, M.1
  • 40
    • 28644432894 scopus 로고    scopus 로고
    • The gene for a lectin-like protein is transcriptionally activated during sexual development, but is not essential for fruiting body formation in the filamentous fungus Sordaria macrospora
    • Nowrousian M., Cebula P. The gene for a lectin-like protein is transcriptionally activated during sexual development, but is not essential for fruiting body formation in the filamentous fungus Sordaria macrospora. BMC Microbiol. 2005, 5:64.
    • (2005) BMC Microbiol. , vol.5 , pp. 64
    • Nowrousian, M.1    Cebula, P.2
  • 41
    • 0032927876 scopus 로고    scopus 로고
    • Cell differentiation during sexual development of the fungus Sordaria macrospora requires ATP citrate lyase activity
    • Nowrousian M., Masloff S., Pöggeler S., Kück U. Cell differentiation during sexual development of the fungus Sordaria macrospora requires ATP citrate lyase activity. Mol. Cell. Biol. 1999, 19:450-460.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 450-460
    • Nowrousian, M.1    Masloff, S.2    Pöggeler, S.3    Kück, U.4
  • 42
    • 18744366950 scopus 로고    scopus 로고
    • Cross-species microarray hybridization to identify developmentally regulated genes in the filamentous fungus Sordaria macrospora
    • Nowrousian M., Ringelberg C., Dunlap J.C., Loros J.J., Kück U. Cross-species microarray hybridization to identify developmentally regulated genes in the filamentous fungus Sordaria macrospora. Mol. Genet. Genomics 2005, 273:137-149.
    • (2005) Mol. Genet. Genomics , vol.273 , pp. 137-149
    • Nowrousian, M.1    Ringelberg, C.2    Dunlap, J.C.3    Loros, J.J.4    Kück, U.5
  • 44
    • 34249304779 scopus 로고    scopus 로고
    • Multiple layers of temporal and spatial control regulate accumulation of the fruiting body-specific protein APP in Sordaria macrospora and Neurospora crassa
    • Nowrousian M., Piotrowski M., Kück U. Multiple layers of temporal and spatial control regulate accumulation of the fruiting body-specific protein APP in Sordaria macrospora and Neurospora crassa. Fungal Genet. Biol. 2007, 44:602-614.
    • (2007) Fungal Genet. Biol. , vol.44 , pp. 602-614
    • Nowrousian, M.1    Piotrowski, M.2    Kück, U.3
  • 46
    • 84860557378 scopus 로고    scopus 로고
    • Whole-genome sequencing of Sordaria macrospora mutants identifies developmental genes
    • Nowrousian M., Teichert I., Masloff S., Kück U. Whole-genome sequencing of Sordaria macrospora mutants identifies developmental genes. G3 (Bethesda) 2012, 2:261-270.
    • (2012) G3 (Bethesda) , vol.2 , pp. 261-270
    • Nowrousian, M.1    Teichert, I.2    Masloff, S.3    Kück, U.4
  • 47
    • 1242277769 scopus 로고    scopus 로고
    • A WD40 repeat protein regulates fungal cell differentiation and can be replaced functionally by the mammalian homologue striatin
    • Pöggeler S., Kück U. A WD40 repeat protein regulates fungal cell differentiation and can be replaced functionally by the mammalian homologue striatin. Eukaryot. Cell 2004, 3:232-240.
    • (2004) Eukaryot. Cell , vol.3 , pp. 232-240
    • Pöggeler, S.1    Kück, U.2
  • 48
    • 33746271568 scopus 로고    scopus 로고
    • Highly efficient generation of signal transduction knockout mutants using a fungal strain deficient in the mammalian ku70 ortholog
    • Pöggeler S., Kück U. Highly efficient generation of signal transduction knockout mutants using a fungal strain deficient in the mammalian ku70 ortholog. Gene 2006, 378:1-10.
    • (2006) Gene , vol.378 , pp. 1-10
    • Pöggeler, S.1    Kück, U.2
  • 49
    • 33646543355 scopus 로고    scopus 로고
    • Microarray and real time PCR analyses reveal mating type-dependent gene expression in a homothallic fungus
    • Pöggeler S., Nowrousian M., Ringelberg C., Loros J.J., Dunlap J.C., Kück U. Microarray and real time PCR analyses reveal mating type-dependent gene expression in a homothallic fungus. Mol. Genet. Genomics 2006, 275:492-503.
    • (2006) Mol. Genet. Genomics , vol.275 , pp. 492-503
    • Pöggeler, S.1    Nowrousian, M.2    Ringelberg, C.3    Loros, J.J.4    Dunlap, J.C.5    Kück, U.6
  • 50
    • 34748922237 scopus 로고    scopus 로고
    • Functional characterization, sequence comparisons and distribution of a polyketide synthase gene required for perithecial pigmentation in some Fusarium species
    • Proctor R.H., Butchko R.A., Brown D.W., Moretti A. Functional characterization, sequence comparisons and distribution of a polyketide synthase gene required for perithecial pigmentation in some Fusarium species. Food Addit. Contam. 2007, 24:1076-1084.
    • (2007) Food Addit. Contam. , vol.24 , pp. 1076-1084
    • Proctor, R.H.1    Butchko, R.A.2    Brown, D.W.3    Moretti, A.4
  • 52
    • 4644244128 scopus 로고    scopus 로고
    • Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum
    • Song Z., Cox R.J., Lazarus C.M., Simpson T.J. Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum. ChemBioChem 2004, 5:1196-1203.
    • (2004) ChemBioChem , vol.5 , pp. 1196-1203
    • Song, Z.1    Cox, R.J.2    Lazarus, C.M.3    Simpson, T.J.4
  • 54
    • 0034887171 scopus 로고    scopus 로고
    • Polyketide biosynthesis: a millenium review
    • Staunton J., Weissman K.J. Polyketide biosynthesis: a millenium review. Nat. Prod. Rep. 2001, 18:380-416.
    • (2001) Nat. Prod. Rep. , vol.18 , pp. 380-416
    • Staunton, J.1    Weissman, K.J.2
  • 55
  • 56
    • 84874019033 scopus 로고    scopus 로고
    • Evolution of genes for secondary metabolism in fungi
    • Springer-Verlag, Berlin, Heidelberg, S. Pöggeler, J. Wöstemeyer (Eds.)
    • Teichert I., Nowrousian M. Evolution of genes for secondary metabolism in fungi. Evolution of Fungi and Fungal-like Organisms, The Mycota XIV 2011, 231-255. Springer-Verlag, Berlin, Heidelberg. S. Pöggeler, J. Wöstemeyer (Eds.).
    • (2011) Evolution of Fungi and Fungal-like Organisms, The Mycota XIV , pp. 231-255
    • Teichert, I.1    Nowrousian, M.2
  • 57
    • 84866637856 scopus 로고    scopus 로고
    • Combining laser microdissection and RNA-seq to chart the transcriptional landscape of fungal development
    • Teichert I., Wolff G., Kück U., Nowrousian M. Combining laser microdissection and RNA-seq to chart the transcriptional landscape of fungal development. BMC Genomics 2012, 13:511.
    • (2012) BMC Genomics , vol.13 , pp. 511
    • Teichert, I.1    Wolff, G.2    Kück, U.3    Nowrousian, M.4
  • 60
    • 0015633705 scopus 로고
    • Regulation of sexual reproduction in Gibberella zeae (Fusarium roseum 'Graminearum') by F-2 (Zearalenone)
    • Wolf J.C., Mirocha C.J. Regulation of sexual reproduction in Gibberella zeae (Fusarium roseum 'Graminearum') by F-2 (Zearalenone). Can. J. Microbiol. 1973, 19:725-734.
    • (1973) Can. J. Microbiol. , vol.19 , pp. 725-734
    • Wolf, J.C.1    Mirocha, C.J.2
  • 61
    • 0026583041 scopus 로고
    • Cot-1, a gene required for hyphal elongation in Neurospora crassa encodes a protein kinase
    • Yarden O., Plamann M., Ebbole D., Yanofsky C. Cot-1, a gene required for hyphal elongation in Neurospora crassa encodes a protein kinase. EMBO J. 1992, 11:2159-2166.
    • (1992) EMBO J. , vol.11 , pp. 2159-2166
    • Yarden, O.1    Plamann, M.2    Ebbole, D.3    Yanofsky, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.