MiR-27a regulates inflammatory response of macrophages by targeting IL-10

Journal of Immunology

Volumn 193, Issue 1, 2014, Pages 327-334

  Xie, Na ^a   Cui, Huachun ^a   Banerjee, Sami ^a   Tan, Zheng ^a   Salomao, Reinaldo ^b   Fu, Mingui ^c   Abraham, Edward ^d   Thannickal, Victor J ^a   Liu, Gang ^a  

^a University of Alabama at Birmingham   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; MICRORNA; MICRORNA 27A; STAT3 PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICRORNAS; STAT3 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84903626316     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400203     Document Type: Article

References (39)

1. Takeuchi, O., and S. Akira. 2010. Pattern recognition receptors and inflammation. Cell 140: 805-820.
2. Kawai, T., and S. Akira. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11: 373-384.
3. Medzhitov, R., and T. Horng. 2009. Transcriptional control of the inflammatory response. Nat. Rev. Immunol. 9: 692-703.
4. Jeannin, P., S. Jaillon, and Y. Delneste. 2008. Pattern recognition receptors in the immune response against dying cells. Curr. Opin. Immunol. 20: 530-537.
5. Salomao, R., M. K. Brunialti, M. M. Rapozo, G. L. Baggio-Zappia, C. Galanos, and M. Freudenberg. 2012. Bacterial sensing, cell signaling, and modulation of the immune response during sepsis. Shock 38: 227-242.
6. Vallabhapurapu, S., and M. Karin. 2009. Regulation and function of NF-kappaB transcription factors in the immune system. Annu. Rev. Immunol. 27: 693-733.
7. Saraiva, M., and A. O'Garra. 2010. The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 10: 170-181.
8. Medzhitov, R., E. M. Shevach, G. Trinchieri, A. L. Mellor, D. H. Munn, S. Gordon, P. Libby, G. K. Hansson, K. Shortman, C. Dong, et al. 2011. Highlights of 10 years of immunology in Nature Reviews Immunology. Nat. Rev. Immunol. 11: 693-702.
9. Murray, P. J., and S. T. Smale. 2012. Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways. Nat. Immunol. 13: 916-924.
10. Couper, K. N., D. G. Blount, and E. M. Riley. 2008. IL-10: the master regulator of immunity to infection. J. Immunol. 180: 5771-5777.
11. Kühn, R., J. Löhler, D. Rennick, K. Rajewsky, and W. Müller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75: 263-274.
12. Bartel, D. P. 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
13. Zeng, Y. 2006. Principles of micro-RNA production and maturation. Oncogene 25: 6156-6162.
14. Engels, B. M., and G. Hutvagner. 2006. Principles and effects of microRNAmediated post-transcriptional gene regulation. Oncogene 25: 6163-6169.
15. Bushati, N., and S. M. Cohen. 2007. microRNA functions. Annu. Rev. Cell Dev. Biol. 23: 175-205.
16. Ambros, V. 2001. microRNAs: tiny regulators with great potential. Cell 107: 823-826.
17. O'Connell, R. M., D. S. Rao, and D. Baltimore. 2012. microRNA regulation of inflammatory responses. Annu. Rev. Immunol. 30: 295-312.
18. Liu, G., and E. Abraham. 2013. MicroRNAs in immune response and macrophage polarization. Arterioscler. Thromb. Vasc. Biol. 33: 170-177.
19. O'Connell, R. M., D. Kahn, W. S. Gibson, J. L. Round, R. L. Scholz, A. A. Chaudhuri, M. E. Kahn, D. S. Rao, and D. Baltimore. 2010. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 33: 607-619.
20. Sheedy, F. J., E. Palsson-McDermott, E. J. Hennessy, C. Martin, J. J. O'Leary, Q. Ruan, D. S. Johnson, Y. Chen, and L. A. O'Neill. 2010. Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat. Immunol. 11: 141-147.
21. Alam, M. M., and L. A. O'Neill. 2011. MicroRNAs and the resolution phase of inflammation in macrophages. Eur. J. Immunol. 41: 2482-2485.
22. Banerjee, S., N. Xie, H. Cui, Z. Tan, S. Yang, M. Icyuz, E. Abraham, and G. Liu. 2013. MicroRNA let-7c regulates macrophage polarization. J. Immunol. 190: 6542-6549.
23. Banerjee, S., H. Cui, N. Xie, Z. Tan, S. Yang, M. Icyuz, V. J. Thannickal, E. Abraham, and G. Liu. 2013. miR-125a-5p regulates differential activation of macrophages and inflammation. J. Biol. Chem. 288: 35428-35436.
24. Liu, G., A. Friggeri, Y. Yang, Y. J. Park, Y. Tsuruta, and E. Abraham. 2009. miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses. Proc. Natl. Acad. Sci. USA 106: 15819-15824.
25. Rossato, M., G. Curtale, N. Tamassia, M. Castellucci, L. Mori, S. Gasperini, B. Mariotti, M. De Luca, M. Mirolo, M. A. Cassatella, et al. 2012. IL-10-induced microRNA-187 negatively regulates TNF-a, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc. Natl. Acad. Sci. USA 109: E3101-E3110.
26. Cheung, S. T., E. Y. So, D. Chang, A. Ming-Lum, and A. L. Mui. 2013. Interleukin-10 inhibits lipopolysaccharide induced miR-155 precursor stability and maturation. PLoS ONE 8: e71336.
27. Lin, L., J. Hou, F. Ma, P. Wang, X. Liu, N. Li, J. Wang, Q. Wang, and X. Cao. 2013. Type I IFN inhibits innate IL-10 production in macrophages through histone deacetylase 11 by downregulating microRNA-145. J. Immunol. 191: 3896-3904.
28. Curtale, G., M. Mirolo, T. A. Renzi, M. Rossato, F. Bazzoni, and M. Locati. 2013. Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b. Proc. Natl. Acad. Sci. USA 110: 11499-11504.
29. Schaefer, J. S., D. Montufar-Solis, N. Vigneswaran, and J. R. Klein. 2011. Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/-mice precedes expression in the colon. J. Immunol. 187: 5834-5841.
30. McCoy, C. E., F. J. Sheedy, J. E. Qualls, S. L. Doyle, S. R. Quinn, P. J. Murray, and L. A. O'Neill. 2010. IL-10 inhibits miR-155 induction by toll-like receptors. J. Biol. Chem. 285: 20492-20498.
31. Dweep, H., C. Sticht, P. Pandey, and N. Gretz. 2011. miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J. Biomed. Inform. 44: 839-847.
32. Pattison, M. J., K. F. Mackenzie, and J. S. Arthur. 2012. Inhibition of JAKs in macrophages increases lipopolysaccharide-induced cytokine production by blocking IL-10-mediated feedback. J. Immunol. 189: 2784-2792.
33. Murray, P. J. 2007. The JAK-STAT signaling pathway: input and output integration. J. Immunol. 178: 2623-2629.
34. Yang, Q., Z. Jie, S. Ye, Z. Li, Z. Han, J.Wu, C. Yang, and Y. Jiang. 2014. Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility. Oncogene 33: 193-202.
35. Mertens-Talcott, S. U., S. Chintharlapalli, X. Li, and S. Safe. 2007. The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res. 67: 11001-11011.
36. Wang, Q., D. C. Li, Z. F. Li, C. X. Liu, Y. M. Xiao, B. Zhang, X. D. Li, J. Zhao, L. P. Chen, X. M. Xing, et al. 2011. Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen. Oncogene 30: 3875-3886.
37. Jones, K. B., Z. Salah, S. Del Mare, M. Galasso, E. Gaudio, G. J. Nuovo, F. Lovat, K. LeBlanc, J. Palatini, R. L. Randall, et al. 2012. miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res. 72: 1865-1877.
38. Hanahan, D., and R. A. Weinberg. 2011. Hallmarks of cancer: the next generation. Cell 144: 646-674.
39. Kundu, J. K., and Y. J. Surh. 2012. Emerging avenues linking inflammation and cancer. Free Radic. Biol. Med. 52: 2013-2037.