Limbic activity in antipsychotic naïve first-episode psychotic subjects during facial emotion discrimination

European Archives of Psychiatry and Clinical Neuroscience

Volumn 264, Issue 4, 2014, Pages 271-283

  Bergé, Daniel ^a,b,c   Carmona, Susanna ^b,c   Salgado, Purificación ^a   Rovira, Mariana ^b,d   Bulbena, Antoni ^a,b,c   Vilarroya, Oscar ^b,c  

^a HOSPITAL DEL MAR   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^d CRC Health Corporation Corporació Sanitària CRC Tavern   (Spain)

Author keywords

Amygdala; fMRI; Psychosis; Schizophrenia

Indexed keywords

NEUROLEPTIC AGENT; OXYGEN;

ADULT; AMYGDALOID NUCLEUS; ARTICLE; CALCARINE SULCUS; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; EMOTION; FACIAL EMOTION DISCRIMINATION; FACIAL EXPRESSION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; LIMBIC SYSTEM; LINGUAL GYRUS; MALE; OCCIPITAL GYRUS; PERCEPTION; PERCEPTIVE DISCRIMINATION; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; PSYCHOSIS; TASK PERFORMANCE; VOXEL BASED MORPHOMETRY; ADOLESCENT; BLOOD; IMAGE PROCESSING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATTERN RECOGNITION; PHOTOSTIMULATION; PHYSIOLOGY; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; VASCULARIZATION; YOUNG ADULT;

ADOLESCENT; ADULT; DISCRIMINATION (PSYCHOLOGY); EMOTIONS; FACIAL EXPRESSION; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; YOUNG ADULT;

EID: 84903625570     PISSN: 09401334     EISSN: 14338491     Source Type: Journal    
DOI: 10.1007/s00406-013-0465-5     Document Type: Article

References (51)

1. Mandal MK, Pandey R, Prasad AB (1998) Facial expressions of emotions and schizophrenia: a review. Schizophr Bull 24:399-412 (Pubitemid 28378225)
2. Chan RCK, Li H, Cheung EFC, Gong Q-Y (2010) Impaired facial emotion perception in schizophrenia: a meta-analysis. Psychiatry Res 178:381-390. doi:10.1016/j.psychres.2009.03.035
3. Adolphs R, Tranel D, Damasio AR (1998) The human amygdala in social judgment. Nature 393:417-418
4. Ochsner KevinN (2008) The social-emotional processing stream: five core constructs and their translational potential for schizophrenia and beyond. Biol Psychiatry 64:48-61
5. Marwick K, Hall J (2008) Social cognition in schizophrenia: a review of face processing. Br Med Bull 88:43-58
6. Addington Jean, Saeedi Huma, Addington Donald (2006) Facial affect recognition: a mediator between cognitive and social functioning in psychosis? Schizophr Res 85:142-150
7. Edwards J, Pattison PE, Jackson HJ, Wales RJ (2001) Facial affect and affective prosody recognition in first-episode schizophrenia. Schizophr Res 48:235-253 (Pubitemid 32274319)
8. Bediou B, Asri F, Brunelin J et al (2007) Emotion recognition and genetic vulnerability to schizophrenia. Br J Psychiatry 191:126-130 (Pubitemid 47204532)
9. Addington J, Penn D, Woods SW et al (2008) Facial affect recognition in individuals at clinical high risk for psychosis. Br J Psychiatry 192:67-68 (Pubitemid 351183164)
10. Brekke JS, Hoe M, Long J, Green MF (2007) How neurocognition and social cognition influence functional change during community-based psychosocial rehabilitation for individuals with schizophrenia. Schizophr Bull 33:1247-1256. doi:10.1093/schbul/sbl072 (Pubitemid 47347914)
11. Haxby JamesV, Hoffman ElizabethA, Ida Gobbini M (2002) Human neural systems for face recognition and social communication. Biol Psychiatry 51:59-67
12. Vuilleumier P, Pourtois G (2007) Distributed and interactive brain mechanisms during emotion face perception: evidence from functional neuroimaging. Neuropsychologia 45:174-194 (Pubitemid 44821236)
13. Kosaka H, Omori M, Murata T et al (2002) Differential amygdala response during facial recognition in patients with schizophrenia: an fMRI study. Schizophr Res 57:87-95. doi:10.1016/S0920-9964(01)00324-3
14. Fernandez-Egea E, Parellada E, Lomeña F et al (2009) (18)FDG PET study of amygdalar activity during facial emotion recognition in schizophrenia. Eur Arch Psychiatry Clin Neurosci. doi:10.1007/s00406-009-0020-6
15. Hall J, Whalley HC, McKirdy JW et al (2008) Overactivation of fear systems to neutral faces in schizophrenia. Biol Psychiatry 64:70-73. doi:10.1016/j.biopsych.2007.12.014
16. Kohler CG, Loughead J, Ruparel K et al (2008) Brain activation during eye gaze discrimination in stable schizophrenia. Schizophr Res 99:286-293. doi:10.1016/j.schres.2007.09.038
17. Holt DJ, Kunkel L, Weiss AP et al (2006) Increased medial temporal lobe activation during the passive viewing of emotional and neutral facial expressions in schizophrenia. Schizophr Res 82:153-162. doi:10.1016/j.schres. 2005.09.021 (Pubitemid 43290679)
18. Gur RE, McGrath C, Chan RM et al (2002) An fMRI study of facial emotion processing in patients with schizophrenia. Am J Psychiatry 159:1992-1999 (Pubitemid 35423857)
19. Johnston PJ, Stojanov W, Devir H, Schall U (2005) Functional MRI of facial emotion recognition deficits in schizophrenia and their electrophysiological correlates. Eur J Neurosci 22:1221-1232 (Pubitemid 41395387)
20. Hempel A, Hempel E, Schönknecht P et al (2003) Impairment in basal limbic function in schizophrenia during affect recognition. Psychiatry Res: Neuroimag 122:115-124. doi:10.1016/S0925-4927(02)00126-9 (Pubitemid 36506477)
21. Gur RE, Loughead J, Kohler CG et al (2007) Limbic activation associated with misidentification of fearful faces and flat affect in schizophrenia. Arch Gen Psychiatry 64:1356-1366 (Pubitemid 350223553)
22. Fakra E, Salgado-Pineda P, Delaveau P et al (2008) Neural bases of different cognitive strategies for facial affect processing in schizophrenia. Schizophr Res 100:191-205. doi:10.1016/j.schres.2007.11.040
23. Das P, Kemp AH, Flynn G et al (2007) Functional disconnections in the direct and indirect amygdala pathways for fear processing in schizophrenia. Schizophr Res 90:284-294. doi:10.1016/j.schres.2006.11.023 (Pubitemid 46188523)
24. Salgado-Pineda P, Fakra E, Delaveau P et al (2010) Differential patterns of initial and sustained responses in amygdala and cortical regions to emotional stimuli in schizophrenia patients and healthy participants. J Psychiatry Neurosci 35:41-48
25. Anticevic A, Van Snellenberg JX, Cohen RE et al (2012) Amygdala recruitment in schizophrenia in response to aversive emotional material: a meta-analysis of neuroimaging studies. Schizophr Bull 38:608-621. doi:10.1093/schbul/sbq131
26. Taylor SF, Kang J, Brege IS et al (2012) Meta-analysis of functional neuroimaging studies of emotion perception and experience in schizophrenia. Biol Psychiatry 71:136-145. doi:10.1016/j.biopsych.2011.09.007
27. Li H, Chan RCK, McAlonan GM, Gong Q (2010) Facial emotion processing in schizophrenia: a meta-analysis of functional neuroimaging data. Schizophr Bull 36(5):1029-1039. doi:10.1093/schbul/sbn190
28. Blasi G, Popolizio T, Taurisano P et al (2009) Changes in prefrontal and amygdala activity during olanzapine treatment in schizophrenia. Psychiatry Res 173:31-38. doi:10.1016/j.pscychresns.2008.09.001
29. Fahim C, Stip E, Mancini-Marïe A et al (2005) Differential hemodynamic brain activity in schizophrenia patients with blunted affect during quetiapine treatment. J Clin Psychopharmacol 25:367-371 (Pubitemid 41060258)
30. Stip E, Fahim C, Mancini-Marïe A et al (2005) Restoration of frontal activation during a treatment with quetiapine: an fMRI study of blunted affect in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 29:21-26. doi:10.1016/j.pnpbp.2004.08.015 (Pubitemid 40018202)
31. Ngan ETC, Lane CJ, Ruth TJ, Liddle PF (2002) Immediate and delayed effects of risperidone on cerebral metabolism in neuroleptic naïve schizophrenic patients: correlations with symptom change. J Neurol Neurosurg Psychiatry 72:106-110 (Pubitemid 34073105)
32. First M (1997) User's guide for the structured clinical interview for DSM-IV axis I disorders SCID-I: clinician version. American Psychiatric Press, Washington
33. Kay SR, Fiszbein A, Vital-Herne M, Fuentes LS (1990) The Positive and Negative Syndrome Scale-Spanish adaptation. J Nerv Ment Dis 178:510-517 (Pubitemid 20256607)
34. Osatuke K, Ciesla J, Kasckow JW et al (2007) Insight in schizophrenia: a review of etiological models and supporting research. Compr Psychiatry 49:70-77. doi:10.1016/j.comppsych.2007.08.001
35. Bora E, Sehitoglu G, Aslier M et al (2007) Theory of mind and unawareness of illness in schizophrenia: is poor insight a mentalizing deficit? Eur Arch Psychiatry Clin Neurosci 257:104-111. doi:10.1007/s00406-006-0681-3 (Pubitemid 46399212)
36. Vaskinn A, Sundet K, Ueland T et al (2013) Social cognition and clinical insight in schizophrenia and bipolar disorder. J Nerv Ment Dis 201:445-451. doi:10.1097/NMD.0b013e31829480c8
37. Amador XF, Flaum M, Andreasen NC et al (1994) Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry 51:826-836 (Pubitemid 24313308)
38. Suzuki T, Remington G, Mulsant BH et al (2012) Defining treatment-resistant schizophrenia and response to antipsychotics: a review and recommendation. Psychiatry Res 197:1-6. doi:10.1016/j.psychres.2012.02.013
39. Ekman P, Friesen WV, O'Sullivan M et al (1987) Universals and cultural differences in the judgments of facial expressions of emotion. J Pers Soc Psychol 53:712-717. doi:10.1037/0022-3514.53.4.712
40. Douglas Ward B (2000) Simultaneous inference for FMRI data. Bophysics Research Institute, Medical College of Wisconsin
41. Cox RW (1996) AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 29:162-173
42. Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH (2003) An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19:1233-1239 (Pubitemid 36918259)
43. Tzourio-Mazoyer N, Landeau B, Papathanassiou D et al (2002) Automated anatomical labelling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 15:273-289. doi:10.1006/nimg 2001.0978
44. Phan KL, Wager T, Taylor SF, Liberzon I (2002) Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. NeuroImage 16:331-348. doi:10.1006/nimg 2002.1087
45. Habel U, Klein M, Shah NJ et al (2004) Genetic load on amygdala hypofunction during sadness in non-affected brothers of schizophrenia patients. Am J Psychiatry 161:1806-1813. doi:10.1176/appi.ajp.161.10.1806 (Pubitemid 39314674)
46. Schneider F, Weiss U, Kessler C et al (1998) Differential amygdala activation in schizophrenia during sadness. SchizophrRes 34:133-142 (Pubitemid 28535473)
47. Taylor SF, Liberzon I, Decker LR, Koeppe RA (2002) A functional anatomic study of emotion in schizophrenia. Schizophr Res 58:159-172 (Pubitemid 35284507)
48. Lee K-H, Brown WH, Egleston PN et al (2006) A functional magnetic resonance imaging study of social cognition in schizophrenia during an acute episode and after recovery. Am J Psychiatry 163:1926-1933. doi:10.1176/appi.ajp. 163.11.1926 (Pubitemid 44807784)
49. Liddle PF, Lane CJ, Ngan ET (2000) Immediate effects of risperidone on cortico-striato-thalamic loops and the hippocampus. BrJPsychiatry 177:402-407
50. Phillips ML, Drevets WC, Rauch SL, Lane R (2003) Neurobiology of emotion perception II: implications for major psychiatric disorders. Biol Psychiatry 54:515-528 (Pubitemid 37289438)
51. Phillips LK, Seidman LJ (2008) Emotion processing in persons at risk for schizophrenia. Schizophr Bull 34:888-903. doi:10.1093/schbul/sbn085