Differential amygdala activation in schizophrenia during sadness

Schizophrenia Research

Volumn 34, Issue 3, 1998, Pages 133-142

  Schneider, F ^a   Weiss, U ^a   Kessler, C ^a   Salloum, J B ^a   Posse, S ^b   Grodd, W ^c   Muller Gartner H W ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Amygdala; Emotion; fMRI; Mood induction

Indexed keywords

CLOZAPINE;

ADULT; AMYGDALOID NUCLEUS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISCRIMINATION LEARNING; DISEASE SEVERITY; GRIEF; HEMISPHERIC DOMINANCE; HUMAN; IMAGE ANALYSIS; MALE; MOOD; NEGATIVE SYNDROME; NEUROBIOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA; TASK PERFORMANCE;

ADULT; AMYGDALA; ANTIPSYCHOTIC AGENTS; BRAIN; EMOTIONS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; SCHIZOPHRENIA;

EID: 0032583141     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(98)00085-1     Document Type: Article

References (33)

1. Andreasen, N.C., 1984a. Scale for the Assessment of Negative Symptoms (SANS). University of Iowa, Iowa City, IA.
2. Andreasen, N.C., 1984b. Scale for the Assessment of Positive Symptoms (SAPS). University of Iowa, Iowa City, IA.
3. Bartko, J.J., Carpenter, W.T., 1976. On the methods and theory of reliability. J. Nerv. Ment. Dis. 163, 307-317.
4. Becker, T., Elmer, K., Schneider, F., Schneider, M., Grodd, W., Bartels, M., Heckers, S., Beckmann, H., 1996. Confirmation of reduced temporal limbic structure volume on magnetic resonance imaging in male patients with schizophrenia. Psychiatry Res.: Neuroimaging 67, 135-143.
5. Bogerts, B., Lieberman, J.A., Ashtari, M., Bilder, R.M., Degreef, G., Lerner, G., Johns, C., Masiar, S., 1993. Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia. Biol. Psychiatry 33, 236-246.
6. Breiter, H.C., Etcoff, N.L., Whalen, P.J., Kennedy, W.A., Rauch, S.L., Buckner, R.L., Strauss, M.M., Hyman, S.E., Rosen, B.R., 1996. Response and habituation of the human amygdala during visual processing of facial expression. Neuron 17, 875-887.
7. Cahill, L., Babinsky, R., Markowitsch, H.J., McGaugh, J.L., 1995. The amygdala and emotional memory. Nature 377, 295-296.
8. Drevets, W.C., Videen, T.O., Price, J.L., Preskorn, S.H., Carmichael, S.T., Raichle, M.E., 1992. A functional anatomical study of unipolar depression. J. Neurosci. 12, 3628-3641.
9. Endicott, J., Spitzer, R.L., Fleiss, J.L., Cohen, J., 1976. The Global Assessment Scale. Arch. Gen. Psychiatry 33, 766-771.
10. Erwin, R.J., Gur, R.C., Gur, R.E., Skolnick, B., Mawhinney-Hee, M., Smailis, J., 1992. Facial emotion discrimination: I. Task construction and behavioral findings in normal subjects. Psychiatry Res. 42, 231-240.
11. Flaum, M., Swayze, V.W. II, O'Leary, D.S., Yuh, W.T., Ehrhardt, J.C., Arndt, S.V., Andreasen, N.C., 1995. Effects of diagnosis, laterality, and gender on brain morphology in schizophrenia. Am. J. Psychiatry 152, 704-714.
12. George, M.S., Ketter, T.A., Parekh, P.I., Horwitz, B., Herscovitch, P., Post, R.M., 1995. Brain activity during transient sadness and happiness in healthy women. Am. J. Psychiatry 152, 341-351.
13. Hamilton, M., 1960. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry 23, 56-62.
14. Heimberg, C., Gur, R.E., Erwin, R.J., Shtasel, D.L., Gur, R.C., 1992. Facial emotion discrimination: III. Behavioral findings in schizophrenia. Psychiatry Res. 42, 231-240.
15. Irwin, W., Davidson, R.J., Lowe, M.J., Mock, B.J., Sorenson, J.A., Turski, P.A., 1996. Human amygdala activation detected with echo-planar functional magnetic resonance imaging. Neuroreport 7, 1765-1769.
16. Joseph, R., 1992. The limbic system: Emotion, laterality, and unconscious mind. Psychoanal. Rev. 79, 405-456.
17. Ketter, T.A., Andreason, P.J., George, M.S., Chulhee, L., Gill, D.S., Parekh, P.I., Willis, M.W., Herscovitch, P., Post, R.M., 1996. Anterior paralimbic mediation of procaine-induced emotional and psychosensory experiences. Arch. Gen. Psychiatry 53, 59-69.
18. Le Doux, J.E., 1995. Emotion: Clues from the brain. Annu. Rev. Psychol. 46, 209-235.
19. Morris, J.S., Frith, C.D., Perrett, D.I., Rowland, D., Young, A.W., Calder, A.J., Dolan, R.J., 1996. A differential neural response in the human amygdala to fearful and happy facial expressions. Nature 383, 812-815.
20. Overall, J.E., Gorham, D.R., 1962. The Brief Psychiatric Rating Scale. Psychol. Rep. 10, 799-812.
21. Pardo, J.V., Pardo, P.J., Raichle, M.E., 1993. Neural correlates of self-induced dysphoria. Am. J. Psychiatry 150, 713-719.
22. Philipps, M.L., Young, A.W., Senior, C., Brammer, M., Andrew, C., Calder, A.J., Bullmore, E.T., Perrett, D.I., Rowland, D., Williams, S.C.R., Gray, J.A., David, A.S., 1997. A specific neural substrate for perceiving facial expressions of disgust. Nature 389, 495-498.
23. Reynolds, G.P., 1992. The amygdala and the neurochemistry of schizophrenia. In: Aggleton, J.P. (Ed.), The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction. Wiley-Liss, New York, pp. 561-574.
24. Rolls, E.T., 1992. Neurophysiology and functions of the primate amygdala. In: Aggleton J.P. (Ed.), The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction. Wiley-Liss, New York, pp. 143-165.
25. Schneider, F., Gur, R.C., Gur, R.E., Muenz, L.R., 1994a. Standardized mood induction with happy and sad facial expressions. Psychiatry Res. 51, 19-31.
26. 133Xenon clearance study. Psychiatry Res. 52, 215-236.
27. Schneider, F., Gur, R.C., Gur, R.E., Shtasel, D.L., 1995a. Neurobehavioral probes in relation to psychopathology. Schizophr. Res. 17, 67-75.
28. Schneider, F., Gur, R.E., Harper Mozley, L., Smith, R.J., Mozley, P.D., Censits, D.M., Alavi, A., Gur, R.C., 1995b. Mood effects on limbic blood flow correlate with emotional self-rating: A PET study with oxygen-15 labeled water. Psychiatry Res.: Neuroimaging 61, 265-283.
29. Schneider, F., Grodd, W., Weiss, U., Klose, U., Mayer, K.R., Nägele, T., Gur, R.C., 1997. Functional MRI reveals left amygdala activation during emotion. Psychiatry Res.: Neuroimaging 76, 75-82.
30. Shtasel, D.L., Gur, R.E., Mozley, P.D., Richards, J., Taleff, M.M., Heimberg, C., Galacher, F., Gur, R.C., 1991. Volunteers for biomedical research: Recruitment and screening of normal controls. Arch. Gen. Psychiatry 48, 1022-1025.
31. Watson, D., Clark, L.A., Tellegen, A., 1988. Development and validation of brief measures of positive and negative affect: The PANAS scales. J. Pers. Soc. Psychol. 54, 1063-1070.
32. Weinberger, D.R., Berman, K.F., Zec, R.F., 1986. Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia: I. Regional cerebral blood flow (rCBF) evidence. Arch. Gen. Psychiatry 43, 114-125.
33. Wittchen, H.-U., Wunderlich, U., Gruschwitz, S., Zaudig, M., 1997. Strukturiertes Klinisches Interview für DSM-IV, Achse-I (SKID) [Structured Clinical Interview for DSM IV]. Göttingen, Hogrefe.