The effects of rebaudioside a on microbial diversity in mouse intestine

Food Science and Technology Research

Volumn 20, Issue 2, 2014, Pages 459-467

  Li, Shengjie ^a   Chen, Tingtao ^a   Dong, Suqin ^a   Xiong, Yonghua ^a   Wei, Hua ^a   Xu, Feng ^a  

^a NANCHANG UNIVERSITY   (China)

Author keywords

Growth effects; Intestinal microbiota; PCR DGGE; Rebaudioside A

Indexed keywords

ELECTROPHORESIS; ESCHERICHIA COLI; PLANTS (BOTANY); POLYMERASE CHAIN REACTION;

DENATURING GRADIENT GEL ELECTROPHORESES (DGGE); GROWTH EFFECTS; HIGH-POTENCY SWEETENERS; MICROBIAL DIVERSITY; MICROBIOTAS; PCR-DGGE; REBAUDIOSIDE-A; STEVIA REBAUDIANA;

BACTERIA;

EID: 84903604677     PISSN: 13446606     EISSN: None     Source Type: Journal    
DOI: 10.3136/fstr.20.459     Document Type: Article

References (39)

1. Boonkaewwan, C., Toskulkao, C., and Vongsakul, M. (2006). Anti-inflammatory and immunomodulatory activities of stevioside and its metabolite steviol on THP-1 cells. J. Agr Food Chem., 54, 785-789.
2. Candela, M., Perna, F., Carnevali, P., Vitali, B., Ciati, R., Gionchetti, P., Rizzello, F., Campieri, M., and Brigidi, P. (2008). Interaction of probiotic Lactobacillus and Bifidobacterium strains with human intestinal epithelial cells: Adhesion properties, competition against enteropathogens and modulation of IL-8 production. Int. J. Food Microbiol., 125, 286-292.
3. Carakostas, M., Curry, L., Boileau, A., and Brusick, D. (2008). Overview: the history, technical function and safety of rebaudioside A, a naturally occurring steviol glycoside, for use in food and beverages. Food Chem. Toxicol., 46, S1-S10.
4. Chan, P., Tomlinson, B., Chen, Y.J., Liu, J.C., Hsieh, M.H., and Cheng, J.T. (2000). A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Brit J. Clin Pharmacol., 50, 215-220.
5. Chen, T., Jiang, S., Xiong, S., Wang, M., Zhu, D., and Wei, H. (2012). Application of denaturing gradient gel electrophoresis to microbial diversity analysis in Chinese Douchi. J. Sci Food Agr., 92, 2171-2176.
6. Chen, T., Wang, M., Jiang, S., Xiong, S., Zhu, D., and Wei, H. (2011a). Investigation of the microbial changes during koji-making process of Douchi by culture dependent techniques and PCR-DGGE. Int. J. Food Sci. Tech., 46, 1878-1883.
7. Chen, T., Yuan, J., Feng, X., Wei, H., and Hua, W. (2011b). Effects of enrofloxacin on the human intestinal microbiota in vitro. Int. J. Antimicrob. Ag., 37, 567-571.
8. Curry, L.L. and Roberts, A. (2008). Subchronic toxicity of rebaudioside A. Food Chem. Toxicol., 46, S11-S20.
9. Curry, L.L. Roberts, A., and Brown, N. (2008). Rebaudioside A: Two-generation reproductive toxicity study in rats. Food Chem. Toxicol., 46, S21-S30.
10. Debnath, M. (2008). Clonal propagation and antimicrobial activity of an endemic medicinal plant Stevia rebaudiana. J. Med. Plant Res., 2, 45-51.
11. Donskey, C.J., Hujer, A.M., Das, S.M., Pultz, N.J., Bonomo, R.A., and Rice, L.B. (2003). Use of denaturing gradient gel electrophoresis for analysis of the stool microbiota of hospitalized patients. J. Microbiol Meth., 54, 249-256.
12. Dyrskog, S.E.U., Jeppesen, P.B., Chen, J., Christensen, L.P., and Hermansen, K. (2005). The diterpene glycoside, rebaudioside A, does not improve glycemic control or affect blood pressure after eight weeks treatment in the Goto-Kakizaki rat. Rev. Diabetic Studies., 2, 136-145.
13. Eckburg, P.B., Bik, E.M., Bernstein, C.N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S.R., Nelson, K.E., and Relman, D.A. (2005). Diversity of the human intestinal microbial flora. Science., 308, 1635-1638. (Pubitemid 40807514
14. Gardana, C., Simonetti, P., Canzi, E., Zanchi, R., and Pietta, P. (2003). Metabolism of stevioside and rebaudioside A from Stevia rebaudiana extracts by human microflora. J. Agric. Food Chem., 51, 6618-6622.
15. Geuns, J.M.C. (2010). Stevia and steviol glycosides. Euprint, Heverlee.
16. Ghosh, S., Subudhi, E., and Nayak, S. (2008). Antimicrobial assay of Stevia rebaudiana Bertoni leaf extracts against 10 pathogens. Int. J. Integrative Biology, 2, 27-31.
17. Gorbach, S.L. (1990). Lactic acid bacteria and human health. Ann Med., 1, 37-41.
18. Gregersen, S., Jeppesen, P.B., Holst, J.J., and Hermansen, K. (2004). Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism, 53, 73-76.
19. Hsieh, M.H., Chan, P., Sue, Y.M., Liu, J.C., Liang, T.H., Huang, T.Y., Tomlinson, B., Chow, M.S.S., Kao, P.F., and Chen, Y.J. (2003). Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther., 25, 2797-2808.
20. Jayaraman, S., Manoharan, M.S., and Illanchezian, S. (2008). In-vitro antimicrobial and antitumor activities of Stevia rebaudiana (Asteraceae) leaf extracts. Trop. J. Pharm. Res., 7, 1143-1149.
21. JECFA, J.F.A.O. (2005) . WHO Exper t Commi t tee on Food Additives,(2006). Steviol Glycosides [Addendum to stevioside]. In Safety evaluation of certain food additives: Sixtythird Meeting of the Joint FAO/WHO Expert on Food Additives 2005, pp. 117-144&638.
22. Jeppesen, P.B., Gregersen, S., Alstrup, K., and Hermansen, K. (2002). Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats. Phytomedicine, 9, 9-14.
23. Jeyaram, K., Mohendro Singh, W., Premarani, T., Devi, A.R., Chanu, K.S., Talukdar, N., and Singh, M.R. (2008). Molecular identification of dominant microflora associated with 'Hawaijar' -A traditional fermented soybean (Glycine max (L.)) food of Manipur, India. Int. J. Food microbiol., 122, 259-268.
24. Lee, C.N., Wong, K.L., Liu, J.C., Chen, Y.J., Cheng, J.T., and Chan, P. (2001). Inhibitory effect of stevioside on calcium influx to produce antihypertension. Planta Med., 67, 796-799.
25. Luo, H., Qi, H., and Zhang, H. (2004). Assessment of the bacterial diversity in fenvalerate-treated soil. World J. Microbiol. Biot., 20, 509-515.
26. Nikiforov, A.I. and Eapen, A.K. (2008). A 90-day oral (dietary) toxicity study of rebaudioside A in Sprague-Dawley rats. Int. J. Toxicol., 27, 65-80.
27. Olszak, T., An, D., Zeissig, S., Vera, M.P., Richter, J., Franke, A., Glickman, J.N., Siebert, R., Baron, R.M., and Kasper, D.L. (2012). Microbial exposure during early life has persistent effects on natural killer T cell function. Scienc., 336, 489-493.
28. Paterson, D.L. (2006). Resistance in gram-negative bacteria: Enterobacteriaceae. Am. J. Infect. Control, 119, S20-S28.
29. PRAKASH, I., CLOS, J.F., and PRAKASH CHATURVEDULA, V.S. (2012). Stability of rebaudioside A under acidic conditions and its degradation products. Food Res. Int., 48, 65-75.
30. Steinmetz, W.E. and Lin, A. (2009). NMR studies of the conformation of the natural sweetener rebaudioside A. Carbohyd. Res., 344, 2533-2538.
31. Tadhani, M., Patel, V., and Subhash, R. (2007). In vitro antioxidant activities of Stevia rebaudiana leaves and callus. J. Food Compos. Anal., 20, 323-329.
32. Tidona, F., Sekse, C., Criscione, A., Jacobsen, M., Bordonaro, S., Marletta, D., and Vegarud, G.E. (2011). Antimicrobial effect of donkeys' milk digested in vitro with human gastrointestinal enzymes. Int. Dairy J., 21, 158-165.
33. Toyoda, K., Matsui, H., Shoda, T., Uneyama, C., Takada, K., and Takahashi, M. (1997). Assessment of the carcinogenicity of stevioside in F344 rats. Food Chem. Toxicol., 35, 597-603.
34. Upreti, M., Smit, J.P., Hagen, E.J., Smolenskaya, V.N., and Prakash, I. (2012). Single Crystal Growth and Structure Determination of the Natural "High Potency" Sweetener Rebaudioside A. Cryst. Growth Des., 12, 990-993.
35. Wang, T.-T. and Lee, B.H. (1997). Plasmids in Lactobacillus. Crit. Rev. Biotechnol., 17, 227-272.
36. Wheeler, A., Boileau, A., Winkler, P., Compton, J., Prakash, I., Jiang, X., and Mandarino, D. (2008). Pharmacokinetics of rebaudioside A and stevioside after single oral doses in healthy men. Food Chem. Toxicol., 46, S54-S60.
37. Williams, L.D. and Burdock, G.A. (2009). Genotoxicity studies on a high-purity rebaudioside A preparation. Food Chem. Toxicol., 47, 1831-1836.
38. WÖlwer-Rieck, U., Tomberg, W., and Wawrzun, A. (2010). Investigations on the stability of stevioside and rebaudioside A in soft drinks. J. Agr. Food Chem., 58, 12216-12220.
39. Xili, L., Chengjiany, B., Eryi, X., Reiming, S., Yuengming, W., Haodong, S., and Zhiyian, H. (1992). Chronic oral toxicity and carcinogenicity study of stevioside in rats. Food Chem Toxicol., 30, 957-965.