An artificial primitive mimic of the Gramicidin-A channel

Nature Communications

Volumn 5, Issue , 2014, Pages

  Barboiu, Mihail ^a   Le Duc, Yann ^a   Gilles, Arnaud ^a   Cazade, Pierre André ^b   Michau, Mathieu ^a   Marie Legrand, Yves ^a   Van Der Lee, Arie ^a   Coasne, Benoît ^b   Parvizi, Paria ^c   Post, Joshua ^c   Fyles, Thomas ^c  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c UNIVERSITY OF VICTORIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; CARBONYL DERIVATIVE; CATION; GRAMICIDIN A; MEMBRANE PROTEIN; NATURAL GAS; PROTON; TRIAZOLE; WATER; CARRIER PROTEIN; GRAMICIDIN; ION; LIPID BILAYER; TRIAZOLE DERIVATIVE;

CARBONYL COMPOUND; NATURAL GAS; OPTICAL PROPERTY; TRANSPORT PROCESS;

ARTICLE; CHEMICAL STRUCTURE; CHIRALITY; CRYSTAL STRUCTURE; HYDROPHILICITY; SIMULATION; LIPID BILAYER; MEMBRANE POTENTIAL; METABOLISM; PATCH CLAMP TECHNIQUE;

GRAMICIDIN; IONS; LIPID BILAYERS; MEMBRANE POTENTIALS; MEMBRANE TRANSPORT PROTEINS; PATCH-CLAMP TECHNIQUES; TRIAZOLES; WATER;

EID: 84903594180     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5142     Document Type: Article

References (37)

1. Roux, B. Computational studies of the gramicidin channel. Acc. Chem. Res. 35, 366-375 (2002
2. Burkhart, B. M., Li, N., Langs, D. A., Pangborn, W. A. & Duax, W. L. The conducting form of gramicidin A is a right-handed double-stranded double helix. Proc. Natl Acad. Sci. USA 95, 12950-12955 (1998 (Pubitemid 28509504)
3. Allen, O., Andersen, S. & Roux, B. Energetics of ion conduction through the gramicidin channel. Proc. Natl Acad. Sci. USA 101, 117-122 (2007
4. Agre, P. Aquaporin water channels. Angew. Chem. Int. Ed. 43, 4278-4290 (2004
5. Mackinnon, R. Potassium channels and the atomic basis of selective ion conduction (Nobel lecture). Angew. Chem. Int. Ed. 43, 4265-4277 (2004
6. Pinto, L. H. et al. A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity. Proc. Natl Acad. Sci. USA 94, 11301-11306 (1997
7. Hu, F., Luo, W. & Hong, M. Mechanisms of proton conduction and gating in Influenza M2 proton channels from solid-state NMR. Science 330, 505-508 (2010
8. Sharma, M. et al. Insight into the mechanism of the influenza A proton channel from a structure in a lipid bilayer. Science 330, 509-511 (2010
9. Smart, O. S., Breed, J., Smith, G. R. & Sansom, M. S. A novel method for structure-based prediction of ion channel conductance properties. Biophys. J. 72, 1109-1126 (1997 (Pubitemid 27113636)
10. Le Duc, Y. et al. Imidazole-quartet water and proton dipolar channels. Angew. Chem. Int. Ed. 50, 11366-11372 (2011
11. Hu, X. B., Chen, Z., Tang, G., Hou, J. L. & Li, Z. T. Single-molecular artificial transmembrane water channels. J. Am. Chem. Soc. 134, 8384-8385 (2012
12. Kaucher, M. S. et al. Selective transport of water mediated by porous dendritic dipeptides. J. Am. Chem. Soc. 129, 11698-11699 (2007 (Pubitemid 47479916)
13. Barboiu, M. Artificial water channels. Angew. Chem. Int. Ed. 51, 11674-11676 (2012
14. Rudick, J. G. & Percec, V. Induced helical backbone conformations of self organizable dendronized polymers. Acc. Chem. Res. 41, 1641-1652 (2008
15. Cazacu, A., Tong, C., van der Lee, A., Fyles, T. M. & Barboiu, M. Columnar self-assembled ureidocrown-ethers-an example of ion-channel organization in lipid bilayers. J. Am. Chem. Soc. 128, 9541-9548 (2006 (Pubitemid 44117111)
16. Ghadiri, M. R., Granja, J. R. & Buehler, L. K. Artificial transmembrane ion channels from self-assembling peptide nanotubes. Nature 369, 301-304 (1994
17. Matile, S. & Sakai, N. In Analytical Methods in Supramolecular Chemistry. (ed. Schalley, C. A.) 381-418 (Wiley-VCH, Weinheim, 2007
18. Fyles, T. M., Loock, D. & Zhou, X. A voltage-gated ion channel based on a bismacrocyclic bolaamphiphile. J. Am. Chem. Soc. 120, 2997-3003 (1998 (Pubitemid 28204512)
19. Davis, J. T. & Spada, G. P. Supramolecular architectures generated by selfassembly of guanosine derivatives. Chem. Soc. Rev. 36, 296-313 (2007
20. Ball, P. Water as an active constituent in cell biology. Chem. Rev. 108, 74-108 (2008 (Pubitemid 351187472)
21. Borgnia, M. J., Kozano, D., Calamita, G., Maloney, P. C. & Agre, P. Functional reconstitution and characterization of AqpZ, the E. coli water channel protein. J. Mol. Biol. 291, 1169-1179 (1999 (Pubitemid 29423779)
22. Pencer, J., White, G. F. & Hallett, F. R. Osmotically induced shape changes of large unilamellar vesicles measured by dynamic light scattering. Biophys. J. 81, 2716-2728 (2001 (Pubitemid 33020058)
23. White, G., Pencer, J. B., Nickel, G., Wood, J. M. & Hallett, F. R. osmotically induced shape changes of large unilamellar vesicles measured by dynamic light scattering. Biophys. J. 71, 2701-2715 (1996
24. de Groot, B. L. & Grubmueller, H. Water permeation across biological membranes: mechanism and dynamics of aquaporin-1 and GlpF. Science 294, 2353-2357 (2001 (Pubitemid 33140559)
25. Cao, Z. et al. Mechanism of fast proton transport along one-dimensional water chains confined in carbon nanotubes. J. Am. Chem. Soc. 132, 11395-11397 (2010
26. Davis, J. T. et al. Ion channel formation from a calix[4]arene amide that binds HCl. J. Am. Chem. Soc. 124, 2267-2278 (2002 (Pubitemid 34267113)
27. Wenzel, M., Hiscock, J. & Gale, P. Anion receptor chemistry: highlights from 2010. Chem. Soc. Rev. 41, 480-520 (2012
28. Chui, J. K. W. & Fyles, T. M. Ionic conductance of synthetic channels: analysis, lessons, and recommendations. Chem. Soc. Rev. 41, 148-175 (2012
29. Eisenmann, G. & Horn, R. Ionic selectivity revisited: the role of kinetic and equilibrium processes in ion permeation through channels. J. Membrane Biol. 76, 197-225 (1983 (Pubitemid 14201481)
30. Pfeifer, J. R., Reiss, P. & Koert, U. Crown-ether gramicidin hybrid ion channels: dehydration-assisted ion selectivity. Angew. Chem. Int. Ed. 45, 501-504 (2006 (Pubitemid 43075851)
31. Oiki, S., Koeppe, R. E. & Andersen, O. S. A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels. Biophys. J. 62, 28-30 (1992
32. Andersen, O. S. & Koeppe, 2nd R. E. Molecular determinants of channel function. Phys. Rev. 72, S89-S158 (1992
33. Lundbaek, J., Collingwood, S., Ingolfsson, H., Kapoor, R. & Andersen, O. S. Lipid bilayer regulation of membrane protein function: Gramicidin channels as molecular force probes. J. R. Soc. Interface 7, 373-395 (2010
34. Sakai, N. et al. Dendritic folate rosettes as ion channels in lipid bilayers. J. Am. Chem. Soc. 128, 2218-2219 (2006
35. Henning, A. & Matile, S. Detection of the activity of ion channels and pores with circular dichroism spectroscopy: G-quartets as functional CD probes within chirogenic vesicles. Chirality 20, 932-937 (2008
36. Ma, L., Melegari, M., Colombini, M. & Davis, J. T. Large and stable transmembrane pores from guanosine-bile acid conjugates. J. Am. Chem. Soc. 130, 2938-2939 (2008 (Pubitemid 351455956)
37. Meier, P. C. Two-parameter Debye-Hückel approximation for the evaluation of mean activity coefficients of 109 electrolytes. Anal. Chim. Acta 136, 363-368 (1982).