Serum bacterial toxins are related to the progression of inflammatory bowel disease

Scandinavian Journal of Gastroenterology

Volumn 49, Issue 7, 2014, Pages 826-833

  Qiu, Huajing ^a   Sun, Xiaomin ^a   Sun, Mingming ^a   He, Chong ^a   Li, Zhong ^a   Liu, Zhanju ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

Clostridium difficile; Escherichia coli O157; Inflammatory bowel disease; Salmonella; Staphylococcus aureus; Toxin

Indexed keywords

BACTERIAL TOXIN; IMMUNOMODULATING AGENT; INFLIXIMAB; MESALAZINE; PREDNISONE; BIOLOGICAL MARKER; MONOCLONAL ANTIBODY; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; AGED; ARTICLE; CLOSTRIDIUM DIFFICILE; CROHN DISEASE; DISEASE COURSE; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI O157; FEMALE; HUMAN; INFLAMMATORY BOWEL DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; ULCERATIVE COLITIS; ADOLESCENT; BLOOD; CASE CONTROL STUDY; COLITIS, ULCERATIVE; MICROBIOLOGY; MIDDLE AGED; PEPTOCLOSTRIDIUM DIFFICILE; SALMONELLA; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES, MONOCLONAL; BACTERIAL TOXINS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CLOSTRIDIUM DIFFICILE; COLITIS, ULCERATIVE; CROHN DISEASE; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI O157; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; SALMONELLA; SEVERITY OF ILLNESS INDEX; STAPHYLOCOCCUS AUREUS; YOUNG ADULT;

EID: 84903593077     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2014.919018     Document Type: Article

References (41)

1. Maloy KJ, Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 2011; 474:298-306
2. Hammer HF. Gut microbiota and inflammatory bowel disease. Dig Dis 2011;29:550-3
3. Xu XR, Liu CQ, Feng BS, Liu ZJ. Dysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease. World J Gastroenterol 2014;20:3255-64
4. Liu ZJ, Yadav PK, Su JL, Wang JS, Fei K. Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease. World J Gastroenterol 2009;15:5784-8
5. Spor A, Koren O, Ley R. Unravelling the effects of the environment and host genotype on the gut microbiome. Nat Rev Microbiol 2011;9:279-90
6. Thorkildsen LT, Nwosu FC, Avershina E, Ricanek P, Perminow G, Brackmann S, et al. Dominant fecal microbiota in newly diagnosed untreated inflammatory bowel disease patients. Gastroenterol Res Pract 2013;2013:636785
7. Leone V, Chang EB, Devkota S. Diet, microbes, and host genetics: The perfect storm in inflammatory bowel diseases. J Gastroenterol 2013;48:315-21
8. Nitzan O, Elias M, Chazan B, Raz R, Saliba W. Clostridium difficile and inflammatory bowel disease: Role in pathogenesis and implications in treatment. World J Gastroenterol 2013; 19:7577-85
9. Issa M, Vijayapal A, Graham MB, Beaulieu DB, Otterson MF, Lundeen S, et al. Impact of Clostridium difficile on inflammatory bowel disease. Clin Gastroenterol Hepatol 2007;5:345-51
10. Berkes J, Viswanathan VK, Savkovic SD, Hecht G. Intestinal epithelial responses to enteric pathogens: Effects on the tight junction barrier, ion transport, and inflammation. Gut 2003; 52:439-51
11. Zhang YG, Wu S, Xia Y, Sun J. Salmonella infection upregulates the leaky protein claudin-2 in intestinal epithelial cells. PLoS One 2013;8:e58606
12. Souza TB, Lozer DM, Kitagawa SM, Spano LC, Silva NP, Scaletsky IC. Real-Time multiplex PCR assay and melting curve analysis for identifying diarrheagenic Escherichia coli. J Clin Microbiol 2013;51:1031-3
13. Page AV, Liles WC. Enterohemorrhagic Escherichia coli Infections and the Hemolytic-Uremic Syndrome. Med Clin North Am 2013;97:681-95
14. Goldwater PN, Bettelheim KA. Role of Non-O157: H7 Escherichia coli in hemolytic uremic syndrome. Clin Infect Dis 2002;35:346-7
15. Small CL, Reid-Yu SA, McPhee JB, Coombes BK. Persistent infection with Crohn's disease-Associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis. Nat Commun 2013;4:1957
16. DeLeo FR, Diep BA, Otto M. Host defense and pathogenesis in Staphylococcus aureus infections. Infect Dis Clin North Am 2009;23:17-34
17. Vesterlund S, Karp M, Salminen S, Ouwehand AC. Staphylococcus aureus adheres to human intestinal mucus but can be displaced by certain lactic acid bacteria. Microbiology 2006;152:1819-26
18. Nikolaus S, Schreiber S. Diagnostics of inflammatory bowel disease. Gastroenterology 2007;133:1670-89
19. Lewis JD, Chuai S, Nessel L, Lichtenstein GR, Aberra FN, Ellenberg JH. Use of the noninvasive components of the Mayo score to assess clinical response in ulcerative colitis. Inflamm Bowel Dis 2008;14:1660-6
20. Satsangi J, Silverberg MS, Vermeire S, Colombel JF. The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications. Gut 2006;55: 749-53
21. Liu C, Xia X, Wu W, Wu R, Tang M, Chen T, et al. Anti-Tumour necrosis factor therapy enhances mucosal healing through down-regulation of interleukin-21 expression and T helper type 17 cell infiltration in Crohn's disease. Clin Exp Immunol 2013;173:102-11
22. Hanauer SB. The expanding role of biologic therapy for IBD. Nat Rev Gastroenterol Hepatol 2010;7:63-4
23. Khor B, Gardet A, Xavier RJ. Genetics and pathogenesis of inflammatory bowel disease. Nature 2011;474:307-17
24. Liu Z, Cao AT, Cong Y. Microbiota regulation of inflammatory bowel disease and colorectal cancer. Semin Cancer Biol 2013;23:543-52
25. Heinlen L, Ballard JD. Clostridium difficile infection. Am J Med Sci 2010;340:247-52
26. Ricciardi R, Ogilvie JW Jr, Roberts PL, Marcello PW, Concannon TW, Baxter NN. Epidemiology of Clostridium difficile colitis in hospitalized patients with inflammatory bowel diseases. Dis Colon Rectum 2009;52:40-5
27. Rodemann JF, Dubberke ER, Reske KA, Seo da H, Stone CD. Incidence of Clostridium difficile infection in inflammatory bowel disease. Clin Gastroenterol Hepatol 2007;5:339-44
28. Ananthakrishnan AN, McGinley EL, Saeian K, Binion DG. Temporal trends in Disease outcomes related to Clostridium difficile infection in patients with inflammatory bowel disease. Inflamm Bowel Dis 2011;17:976-83
29. Binion DG. Clostridium difficile infection in patients with inflammatory bowel disease. Gastroenterol Hepatol 2012;8: 615-17
30. Clayton EM, Rea MC, Shanahan F, Quigley EM, Kiely B, Hill C, et al. The vexed relationship between Clostridium difficile and inflammatory bowel disease: An assessment of carriage in an outpatient setting among patients in remission. Am J Gastroenterol 2009;104:1162-9
31. Nguyen GC, Patel H, Chong RY. Increased prevalence of and associated mortality with methicillin-resistant Staphylococcus aureus among hospitalized IBD patients. Am J Gastroenterol 2010;105:371-7
32. Lu J, Wang A, Ansari S, Hershberg RM, Mckay DM. Colonic bacterial superantigens evoke an inflammatory response and exaggerate disease in mice recovering from colitis. Gastroenterology 2003;125:1785-95
33. Issa M, Ananthakrishnan AN, Binion DG. Clostridium difficile and inflammatory bowel disease. Inflamm Bowel Dis 2008;14:1432-42
34. Mann SD, Pitt J, Springall RG, Thillainayagam AV. Clostridium difficile infection-An unusual cause of refractory pouchitis: Report of a case. Dis Colon Rectum 2003;46: 267-70
35. Ben-Horin S, Margalit M, Bossuyt P, Maul J, Shapira Y, Bojic D, et al. Prevalence and clinical impact of endoscopic pseudomembranes in patients with inflammatory bowel disease and Clostridium difficile infection. J Crohns Colitis 2010;4:194-8
36. Ananthakrishnan AN, McGinley EL, Binion DG. Excess hospitalisation burden associated with Clostridium difficile in patients with inflammatory bowel disease. Gut 2008;57: 205-10
37. Bettenworth D, Nowacki TM, Friedrich A, Becker K, Wessling J, Heidemann J. Crohn's disease complicated by intestinal infection with methicillin- resistant Staphylococcus aureus. World J Gastroenterol 2013;19:4418-21
38. Mylonaki M, Langmead L, Pantes A, Johnson F, Rampton DS. Enteric infection in relapse of inflammatory bowel disease: Importance of microbiological examination of stool. Eur J Gastroenterol Hepatol 2004;16:775-8
39. Rath HC, Wilson KH, Sartor RB. Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. Infect Immun 1999;67:2969-74
40. Dieleman LA, Goerres MS, Arends A, Sprengers D, Torrice C, Hoentjen F, et al. Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment. Gut 2003;52:370-6
41. Wang Y, Atreja A, Wu X, Lashner BA, Brzezinski A, Shen B. Similar outcomes of IBD inpatients with Clostridium difficile infection Detected by ELISA or PCR assay. Dig Dis Sci 2013; 58:2308-13.