-
1
-
-
0008451644
-
Acceptor substrates of UDP glucuronosyltransferase and their assay
-
Dutton, G. J. (ed), Boca Raton, CRC Press
-
Dutton, G. J.: Acceptor substrates of UDP glucuronosyltransferase and their assay. In Dutton, G. J. (ed): Glucuronidation of Drugs and Other Compounds, Boca Raton, CRC Press, 1980, pp. 69-78.
-
(1980)
Glucuronidation of Drugs and Other Compounds
, pp. 69-78
-
-
Dutton, G.J.1
-
2
-
-
25144500468
-
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily
-
Mackenzie, P. I., Bock, K. W., Burchell, B., Guillemette, C., Ikushiro, S., Iyanagi, T., Miners, J. O., Owens, I. S. and Nebert, D. W.: Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. Pharmacogenet. Genomics, 15: 677-685 (2005).
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 677-685
-
-
Mackenzie, P.I.1
Bock, K.W.2
Burchell, B.3
Guillemette, C.4
Ikushiro, S.5
Iyanagi, T.6
Miners, J.O.7
Owens, I.S.8
Nebert, D.W.9
-
3
-
-
0026701911
-
A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini
-
Ritter, J. K., Chen, F., Sheen, Y. Y., Tran, H. M., Kimura, S., Yeatman, M. T. and Owens, I. S.: A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. J. Biol. Chem., 267: 3257-3261 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3257-3261
-
-
Ritter, J.K.1
Chen, F.2
Sheen, Y.Y.3
Tran, H.M.4
Kimura, S.5
Yeatman, M.T.6
Owens, I.S.7
-
4
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression and disease
-
Tukey, R. H. and Strassburg, C. P.: Human UDP-glucuronosyltransferases: metabolism, expression and disease. Annu. Rev. Pharmacol. Toxicol., 40: 581-616 (2000).
-
(2000)
Annu. Rev. Pharmacol. Toxicol.
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
5
-
-
6944221357
-
Drug-drug interactions for UDP-glucuronosyltransferase substrates: A pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios
-
Williams, J. A., Hyland, R., Jones, B. C., Smith, D. A., Hurst, S., Goosen, T. C., Peterkin, V., Koup, J. R. and Ball, S. E.: Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios. Drug Metab. Dispos., 32: 1201-1208 (2004).
-
(2004)
Drug Metab. Dispos.
, vol.32
, pp. 1201-1208
-
-
Williams, J.A.1
Hyland, R.2
Jones, B.C.3
Smith, D.A.4
Hurst, S.5
Goosen, T.C.6
Peterkin, V.7
Koup, J.R.8
Ball, S.E.9
-
6
-
-
0036266825
-
Imipramine N-glucuronidation in human liver microsomes: Biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms
-
Nakajima, M., Tanaka, E., Kobayashi, T., Ohashi, N., Kume, T. and Yokoi, T.: Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms. Drug Metab. Dispos., 30: 636-642 (2002).
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 636-642
-
-
Nakajima, M.1
Tanaka, E.2
Kobayashi, T.3
Ohashi, N.4
Kume, T.5
Yokoi, T.6
-
7
-
-
33344473930
-
Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline androsterone canrenoic acid hecogenin phenylbutazone quinidine quinine and sulfinpyrazone) "probes" for human udp-glucuronosyltransferases
-
Uchaipichat, V., Mackenzie, P. I., Elliot, D. J. and Miners, J. O.: Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) "probes" for human udp-glucuronosyltransferases. Drug Metab. Dispos., 34: 449-456 (2006).
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 449-456
-
-
Uchaipichat, V.1
Mackenzie, P.I.2
Elliot, D.J.3
Miners, J.O.4
-
8
-
-
0024566868
-
An investigation of the transverse topology of bilirubin UDP-glucuronosyltransferase in rat hepatic endoplasmic reticulum
-
Shepherd, S. R., Baird, S. J., Hallinan, T. and Burchell, B.: An investigation of the transverse topology of bilirubin UDP- glucuronosyltransferase in rat hepatic endoplasmic reticulum. Biochem. J., 259: 617-620 (1989).
-
(1989)
Biochem. J.
, vol.259
, pp. 617-620
-
-
Shepherd, S.R.1
Baird, S.J.2
Hallinan, T.3
Burchell, B.4
-
9
-
-
4444357453
-
Evidence for multiple glucuronide transporters in rat liver microsomes
-
Csala, M., Staines, A. G., Bánhegyi, G., Mandl, J., Coughtrie, M. W. and Burchell, B.: Evidence for multiple glucuronide transporters in rat liver microsomes. Biochem. Pharmacol., 68: 1353-1362 (2004).
-
(2004)
Biochem. Pharmacol.
, vol.68
, pp. 1353-1362
-
-
Csala, M.1
Staines, A.G.2
Bánhegyi, G.3
Mandl, J.4
Coughtrie, M.W.5
Burchell, B.6
-
10
-
-
0035917894
-
Molecular characterization of human UDP-glucuronic acid/UDP-N- acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity
-
Muraoka, M., Kawakita, M. and Ishida, N.: Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity. FEBS Lett., 495: 87-93 (2001).
-
(2001)
FEBS Lett.
, vol.495
, pp. 87-93
-
-
Muraoka, M.1
Kawakita, M.2
Ishida, N.3
-
11
-
-
34748865637
-
Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation
-
Zheng, Y., Sun, D., Sharma, A. K., Chen, G., Amin, S. and Lazarus, P.: Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metab. Dispos., 35: 1942-1948 (2007).
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 1942-1948
-
-
Zheng, Y.1
Sun, D.2
Sharma, A.K.3
Chen, G.4
Amin, S.5
Lazarus, P.6
-
12
-
-
31344445949
-
Interindividual variability in nicotine metabolism: C-oxidation and glucuronidation
-
Nakajima, M. and Yokoi, T.: Interindividual variability in nicotine metabolism: C-oxidation and glucuronidation. Drug Metab. Pharmacokinet., 20: 227-235 (2005).
-
(2005)
Drug Metab. Pharmacokinet.
, vol.20
, pp. 227-235
-
-
Nakajima, M.1
Yokoi, T.2
-
13
-
-
38449093974
-
Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDPglucuronosyltransferases (UGTs): Evidence for the functionally active UGT in P450-UGT complex
-
Ishii, Y., Iwanaga, M., Nishimura, Y., Takeda, S., Ikushiro, S., Nagata, K., Yamazoe, Y., Mackenzie, P. I. and Yamada, H.: Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDPglucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex. Drug Metab. Pharmacokinet., 22: 367-376 (2007).
-
(2007)
Drug Metab. Pharmacokinet.
, vol.22
, pp. 367-376
-
-
Ishii, Y.1
Iwanaga, M.2
Nishimura, Y.3
Takeda, S.4
Ikushiro, S.5
Nagata, K.6
Yamazoe, Y.7
Mackenzie, P.I.8
Yamada, H.9
-
14
-
-
0034647835
-
Interaction between cytochrome P450 and other drug-metabolizing enzymes: Evidence for an association of CYP1A1 with microsomal epoxide hydrolase and UDP-glucuronosyltransferase
-
Taura, K. I., Yamada, H., Hagino, Y., Ishii, Y., Mori, M. A. and Oguri, K.: Interaction between cytochrome P450 and other drug-metabolizing enzymes: evidence for an association of CYP1A1 with microsomal epoxide hydrolase and UDP-glucuronosyltransferase. Biochem. Biophys. Res. Commun., 273: 1048-1052 (2000).
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 1048-1052
-
-
Taura, K.I.1
Yamada, H.2
Hagino, Y.3
Ishii, Y.4
Mori, M.A.5
Oguri, K.6
-
15
-
-
1942446288
-
Functional co-expression of xenobiotic metabolizing enzymes, rat cytochrome P450 1A1 and UDP-glucuronosyltransferase 1A6, in yeast microsomes
-
Ikushiro, S., Sahara, M., Emi, Y., Yabusaki, Y. and Iyanagi, T.: Functional co-expression of xenobiotic metabolizing enzymes, rat cytochrome P450 1A1 and UDP-glucuronosyltransferase 1A6, in yeast microsomes. Biochim. Biophys. Acta, 1672: 86-92 (2004).
-
(2004)
Biochim. Biophys. Acta
, vol.1672
, pp. 86-92
-
-
Ikushiro, S.1
Sahara, M.2
Emi, Y.3
Yabusaki, Y.4
Iyanagi, T.5
-
16
-
-
38849197491
-
The UDP-glucuronosyltransferases as oligomeric enzymes
-
Finel, M. and Kurkela, M.: The UDP-glucuronosyltransferases as oligomeric enzymes. Curr. Drug Metab., 9: 70-76 (2008).
-
(2008)
Curr. Drug Metab.
, vol.9
, pp. 70-76
-
-
Finel, M.1
Kurkela, M.2
-
17
-
-
73949088338
-
Interactions between human UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A enzymes
-
Fujiwara, R., Nakajima, M., Oda, S., Yamanaka, H., Ikushiro, S., Sakaki, T. and Yokoi, T.: Interactions between human UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A enzymes. J. Pharm. Sci., 99: 442-454 (2010).
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 442-454
-
-
Fujiwara, R.1
Nakajima, M.2
Oda, S.3
Yamanaka, H.4
Ikushiro, S.5
Sakaki, T.6
Yokoi, T.7
-
18
-
-
34548097015
-
Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activities
-
Fujiwara, R., Nakajima, M., Yamanaka, H., Katoh, M. and Yokoi, T.: Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activities. Drug Metab. Dispos., 35: 1781-1787 (2007).
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 1781-1787
-
-
Fujiwara, R.1
Nakajima, M.2
Yamanaka, H.3
Katoh, M.4
Yokoi, T.5
-
19
-
-
34247379533
-
Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms
-
Fujiwara, R., Nakajima, M., Yamanaka, H., Nakamura, A., Katoh, M., Ikushiro, S., Sakaki, T. and Yokoi, T.: Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms. Drug Metab. Dispos., 35: 747-757 (2007).
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 747-757
-
-
Fujiwara, R.1
Nakajima, M.2
Yamanaka, H.3
Nakamura, A.4
Katoh, M.5
Ikushiro, S.6
Sakaki, T.7
Yokoi, T.8
-
20
-
-
80052638112
-
Transportsomes and channelsomes: Are they functional units for physiological responses?
-
Mori, Y., Kiyonaka, S. and Kanai, Y.: Transportsomes and channelsomes: are they functional units for physiological responses? Channels, 5: 387- 390 (2011).
-
(2011)
Channels
, vol.5
, pp. 387-390
-
-
Mori, Y.1
Kiyonaka, S.2
Kanai, Y.3
-
21
-
-
84886067237
-
Importance of UDP-glucuronosyltransferase 1A1 expression in skin and its induction by UVB in neonatal hyperbilirubinemia
-
Sumida, K., Kawana, M., Kouno, E., Itoh, T., Takano, S., Narawa, T., Tukey, R. H. and Fujiwara, R.: Importance of UDP-glucuronosyltransferase 1A1 expression in skin and its induction by UVB in neonatal hyperbilirubinemia. Mol. Pharmacol., 84: 679-686 (2013).
-
(2013)
Mol. Pharmacol.
, vol.84
, pp. 679-686
-
-
Sumida, K.1
Kawana, M.2
Kouno, E.3
Itoh, T.4
Takano, S.5
Narawa, T.6
Tukey, R.H.7
Fujiwara, R.8
-
22
-
-
77950407754
-
Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus
-
Fujiwara, R., Nguyen, N., Chen, S. and Tukey, R. H.: Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus. Proc. Natl. Acad. Sci. USA, 107: 5024-5029 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 5024-5029
-
-
Fujiwara, R.1
Nguyen, N.2
Chen, S.3
Tukey, R.H.4
-
23
-
-
43149094663
-
High-accuracy prediction of carcinogenicity by global quantitative analysis of post-translational modifications in a 28-day in vivo rat study
-
Yamanaka, H., Yakabe, Y., Saito, K., Sekijima, M., Sato, H. and Shirai, T.: High-accuracy prediction of carcinogenicity by global quantitative analysis of post-translational modifications in a 28-day in vivo rat study. Cancer Genomics Proteomics, 5: 105-116 (2008).
-
(2008)
Cancer Genomics Proteomics
, vol.5
, pp. 105-116
-
-
Yamanaka, H.1
Yakabe, Y.2
Saito, K.3
Sekijima, M.4
Sato, H.5
Shirai, T.6
-
24
-
-
63849272821
-
Interaction of cytochrome P450 3A4 and UDP-glucuronosyltransferase 2B7: Evidence for protein- protein association and possible involvement of CYP3A4 J-helix in the interaction
-
Takeda, S., Ishii, Y., Iwanaga, M., Nurrochmad, A., Ito, Y., Mackenzie, P. I., Nagata, K., Yamazoe, Y., Oguri, K., et al.: Interaction of cytochrome P450 3A4 and UDP-glucuronosyltransferase 2B7: evidence for protein- protein association and possible involvement of CYP3A4 J-helix in the interaction. Mol. Pharmacol., 75: 956-964 (2009).
-
(2009)
Mol. Pharmacol.
, vol.75
, pp. 956-964
-
-
Takeda, S.1
Ishii, Y.2
Iwanaga, M.3
Nurrochmad, A.4
Ito, Y.5
Mackenzie, P.I.6
Nagata, K.7
Yamazoe, Y.8
Oguri, K.9
-
25
-
-
11244283497
-
Coimmunoprecipitation of UDP-glucuronosyltransferase isoforms and cytochrome P450 3A4
-
Fremont, J. J., Wang, R. W. and King, C. D.: Coimmunoprecipitation of UDP-glucuronosyltransferase isoforms and cytochrome P450 3A4. Mol. Pharmacol., 67: 260-262 (2005).
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 260-262
-
-
Fremont, J.J.1
Wang, R.W.2
King, C.D.3
-
26
-
-
0037098410
-
Activation of microsomal epoxide hydrolase by interaction with cytochromes P450: Kinetic analysis of the association and substratespecific activation of epoxide hydrolase function
-
Taura, K., Yamada, H., Naito, E., Ariyoshi, N., Mori, M. and Oguri, K.: Activation of microsomal epoxide hydrolase by interaction with cytochromes P450: kinetic analysis of the association and substratespecific activation of epoxide hydrolase function. Arch. Biochem. Biophys., 402: 275-280 (2002).
-
(2002)
Arch. Biochem. Biophys.
, vol.402
, pp. 275-280
-
-
Taura, K.1
Yamada, H.2
Naito, E.3
Ariyoshi, N.4
Mori, M.5
Oguri, K.6
-
27
-
-
84877076702
-
Evaluation of UGT protein interactions in human hepatocytes: Effect of siRNA down regulation of UGT1A9 and UGT2B7 on propofol glucuronidation in human hepatocytes
-
Konopnicki, C. M., Dickmann, L. J., Tracy, J. M., Tukey, R. H., Wienkers, L. C. and Foti, R. S.: Evaluation of UGT protein interactions in human hepatocytes: effect of siRNA down regulation of UGT1A9 and UGT2B7 on propofol glucuronidation in human hepatocytes. Arch. Biochem. Biophys., 535: 143-149 (2013).
-
(2013)
Arch. Biochem. Biophys.
, vol.535
, pp. 143-149
-
-
Konopnicki, C.M.1
Dickmann, L.J.2
Tracy, J.M.3
Tukey, R.H.4
Wienkers, L.C.5
Foti, R.S.6
-
28
-
-
33644839193
-
Regulation of drug transporters by PDZ adaptor proteins and nuclear receptors
-
Kato, Y., Watanabe, C. and Tsuji, A.: Regulation of drug transporters by PDZ adaptor proteins and nuclear receptors. Eur. J. Pharm. Sci., 27: 487-500 (2006).
-
(2006)
Eur. J. Pharm. Sci.
, vol.27
, pp. 487-500
-
-
Kato, Y.1
Watanabe, C.2
Tsuji, A.3
-
29
-
-
79961180436
-
Triton X-114 phase separation in the isolation and purification of mouse liver microsomal membrane proteins
-
Mathias, R. A., Chen, Y. S., Kapp, E. A., Greening, D. W., Mathivanan, S. and Simpson, R. J.: Triton X-114 phase separation in the isolation and purification of mouse liver microsomal membrane proteins. Methods, 54: 396-406 (2011).
-
(2011)
Methods
, vol.54
, pp. 396-406
-
-
Mathias, R.A.1
Chen, Y.S.2
Kapp, E.A.3
Greening, D.W.4
Mathivanan, S.5
Simpson, R.J.6
|