Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 57, Issue 7, 2014, Pages 441-447

  Wagner, Thomas ^a   Zeglis, Brian M ^b   Groveman, Sam ^c   Hille, Claudia ^a   Pöthig, Alexander ^a   Francesconi, Lynn C ^c   Herrmann, Wolfgang A ^a   Kühn, Fritz E ^a   Reiner, Thomas ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

N heterocyclic carbene; radiopharmaceutical application; transmetalation

Indexed keywords

ORGANOMETALLICS; RHENIUM COMPOUNDS; SILVER COMPOUNDS;

AIR STABLE; BIS-CARBENE; HEXAFLUOROPHOSPHATES; N-HETEROCYCLIC; N-HETEROCYCLIC CARBENE COMPLEX; N-HETEROCYCLIC CARBENES; RADIOPHARMACEUTICAL APPLICATION; RHENIUM COMPLEXES; SYNTHESISED; TRANSMETALATION;

SYNTHESIS (CHEMICAL);

1,1' METHYLENE BIS(3,3' DIISOPROPYLIMIDAZOLIUM) DIHEXAFLUOROPHOSPHATE; DIOXOBIS[1,1' METHYLENE BIS (3,3' DIISOPROPYLIMIDAZOLIUM 2 YLIDENE)] RE 188; DI[1,1' METHYLENE BIS(3,3' DIISOPROPYLIMIDAZOLIUM 2 YLIDENE)] DISILVER(I) DIHEXAFLUOROPHOSPHATE; N ISOPROPYLIMIDAZOLE; RADIOPHARMACEUTICAL AGENT; TRANS DIOXOBIS[1,1' METHYLENE BIS (3,3' DIISOPROPYLIMIDAZOLIUM 2 YLIDENE)] RE 188; TRICHLORO OXO BIS (TRIPHENYLPHOSPHINE)RE 188; UNCLASSIFIED DRUG; CARBENE; COORDINATION COMPOUND; IMIDAZOLE DERIVATIVE; METHANE; RADIOISOTOPE; RHENIUM;

ARTICLE; DRUG DECOMPOSITION; DRUG SYNTHESIS; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; ISOTOPE LABELING; MOISTURE; NUCLEOPHILICITY; OXIDATION; RADIOCHEMISTRY; TEMPERATURE STRESS;

COORDINATION COMPLEXES; IMIDAZOLES; METHANE; RADIOISOTOPES; RADIOPHARMACEUTICALS; RHENIUM;

EID: 84903551125     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.3203     Document Type: Article

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