A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Siggers, Pam ^a   Carré, Gwenn Aël ^a   Bogani, Debora ^a,b   Warr, Nick ^a   Wells, Sara ^b   Hilton, Helen ^a   Esapa, Chris ^a   Hajihosseini, Mohammad K ^c   Greenfield, Andy ^a  

^a MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

^b Medical Research Council Harwell Institute   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 2B; FIBROBLAST GROWTH FACTOR RECEPTOR 2C; MITOGEN ACTIVATED PROTEIN KINASE; TESTIS DETERMINING FACTOR; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; FGFR2 PROTEIN, MOUSE;

ADULT; ALLELE; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; C57BL 6 MOUSE; EMBRYO; FGFR2 GENE; GENETIC CROSS; GONAD DEVELOPMENT; HOBBYHORSE MUTATION; HOMOZYGOSITY; LIMB DEFECT; LUNG HYPOPLASIA; MISSENSE MUTATION; MOUSE; MUTATION; NONHUMAN; PHENOTYPE; POINT MUTATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEX DETERMINATION; SEX TRANSFORMATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; CELL CULTURE; CONGENITAL MALFORMATION; ENZYME IMMUNOASSAY; FEMALE; GENETICS; GONAD; GONADAL DYSGENESIS; HOMOZYGOTE; HUMAN; LIMB; LUNG DISEASE; MALE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHYSIOLOGY; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; EMBRYO, MAMMALIAN; EXTREMITIES; FEMALE; GONADAL DYSGENESIS; GONADS; HOMOZYGOTE; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG DISEASES; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84903548146     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100447     Document Type: Article

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