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Volumn 78, Issue 3, 2014, Pages 168-175

In-vitro immunosuppression of canine T-lymphocyte-specific proliferation with dexamethasone, cyclosporine, and the active metabolites of azathioprine and leflunomide in a flow-cytometric assay

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CD5 ANTIGEN; CONCANAVALIN A; CYCLOSPORIN; DEXAMETHASONE; LEFLUNOMIDE; PROPIDIUM IODIDE; ANILINE DERIVATIVE; HYDROXYBUTYRIC ACID; IMMUNOSUPPRESSIVE AGENT; ISOXAZOLE DERIVATIVE; MERCAPTOPURINE; TERIFLUNOMIDE;

EID: 84903530920     PISSN: 08309000     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (34)
  • 1
    • 0346873938 scopus 로고    scopus 로고
    • Immune-mediated hemolytic anemia: Understanding the nemesis
    • McCullough S. Immune-mediated hemolytic anemia: Understanding the nemesis. Vet Clin North Am Small Anim Pract 2003;33:1295-1315.
    • (2003) Vet Clin North Am Small Anim Pract , vol.33 , pp. 1295-1315
    • McCullough, S.1
  • 2
    • 70349670886 scopus 로고    scopus 로고
    • Prospective, randomized, double-blinded, placebo-controlled study of human intravenous immunoglobulin for the acute management of presumptive primary immune-mediated thrombocytopenia in dogs
    • Bianco D, Armstrong PJ, Washabau RJ. Prospective, randomized, double-blinded, placebo-controlled study of human intravenous immunoglobulin for the acute management of presumptive primary immune-mediated thrombocytopenia in dogs. J Vet Intern Med 2009;23:1071-1078.
    • (2009) J Vet Intern Med , vol.23 , pp. 1071-1078
    • Bianco, D.1    Armstrong, P.J.2    Washabau, R.J.3
  • 3
    • 84873166951 scopus 로고    scopus 로고
    • Prothrombotic mechanisms and anticoagulant therapy in dogs with immune-mediated hemolytic anemia
    • Kidd L, Mackman N. Prothrombotic mechanisms and anticoagulant therapy in dogs with immune-mediated hemolytic anemia. J Vet Emerg Crit Care 2013;23:3-13.
    • (2013) J Vet Emerg Crit Care , vol.23 , pp. 3-13
    • Kidd, L.1    McKman, N.2
  • 4
    • 0035864857 scopus 로고    scopus 로고
    • Influence of drug treatment on survival of dogs with immune-mediated hemolytic anemia: 88 cases (1989-1999)
    • Grundy SA, Barton C. Influence of drug treatment on survival of dogs with immune-mediated hemolytic anemia: 88 cases (1989-1999). J Am Vet Med Assoc 2001;218:543-546.
    • (2001) J Am Vet Med Assoc , vol.218 , pp. 543-546
    • Grundy, S.A.1    Barton, C.2
  • 5
    • 42449093775 scopus 로고    scopus 로고
    • Idiopathic immune-mediated hemolytic anemia: Treatment outcome and prognostic factors in 149 dogs
    • Piek CJ, Junius G, Dekker A, Schrauwen E, Slappendel RJ, Teske E. Idiopathic immune-mediated hemolytic anemia: Treatment outcome and prognostic factors in 149 dogs. J Vet Intern Med 2008;22:366-373.
    • (2008) J Vet Intern Med , vol.22 , pp. 366-373
    • Piek, C.J.1    Junius, G.2    Dekker, A.3    Schrauwen, E.4    Slappendel, R.J.5    Teske, E.6
  • 6
    • 0032858366 scopus 로고    scopus 로고
    • Immune-mediated hemolytic anemia: 70 cases (1988-1996)
    • Reimer ME, Troy GC, Warnick LD. Immune-mediated hemolytic anemia: 70 cases (1988-1996). J Am Anim Hosp Assoc 1999; 35:384-391.
    • (1999) J Am Anim Hosp Assoc , vol.35 , pp. 384-391
    • Reimer, M.E.1    Troy, G.C.2    Warnick, L.D.3
  • 7
    • 58149137195 scopus 로고    scopus 로고
    • Primary immune-mediated thrombocytopenia in 30 dogs (1997-2003)
    • Putsche JC, Kohn B. Primary immune-mediated thrombocytopenia in 30 dogs (1997-2003). J Am Anim Hosp Assoc 2008;44: 250-257.
    • (2008) J Am Anim Hosp Assoc , vol.44 , pp. 250-257
    • Putsche, J.C.1    Kohn, B.2
  • 8
    • 0034218731 scopus 로고    scopus 로고
    • Treatment of immunemediated hemolytic anemia in dogs with cyclophosphamide
    • Burgess K, Moore A, Rand W, Cotter SM. Treatment of immunemediated hemolytic anemia in dogs with cyclophosphamide. J Vet Intern Med 2000;14:456-462.
    • (2000) J Vet Intern Med , vol.14 , pp. 456-462
    • Burgess, K.1    Moore, A.2    Rand, W.3    Cotter, S.M.4
  • 9
    • 19744376787 scopus 로고    scopus 로고
    • Evaluation of prognostic factors, survival rates, and treatment protocols for immune-mediated hemolytic anemia in dogs: 151 cases (1993-2002)
    • Weinkle TK, Center SA, Randolph JF, Warner KL, Barr SC, Erb HN. Evaluation of prognostic factors, survival rates, and treatment protocols for immune-mediated hemolytic anemia in dogs: 151 cases (1993-2002). J Am Vet Med Assoc 2005;226: 1869-1880.
    • (2005) J Am Vet Med Assoc , vol.226 , pp. 1869-1880
    • Weinkle, T.K.1    Center, S.A.2    Randolph, J.F.3    Warner, K.L.4    Barr, S.C.5    Erb, H.N.6
  • 10
    • 0033811781 scopus 로고    scopus 로고
    • Pharmacodynamics of immunosuppressive drugs
    • Dambin C, Klupp J, Morris R. Pharmacodynamics of immunosuppressive drugs. Curr Opin Immunol 2000;12:557-562.
    • (2000) Curr Opin Immunol , vol.12 , pp. 557-562
    • Dambin, C.1    Klupp, J.2    Morris, R.3
  • 11
    • 81355138258 scopus 로고    scopus 로고
    • Pharmacodynamic monitoring of canine T-cell cytokine responses to oral cyclosporine
    • Archer TM, Fellman CL, Stokes JV, et al. Pharmacodynamic monitoring of canine T-cell cytokine responses to oral cyclosporine. J Vet Intern Med 2011;25:1391-1397.
    • (2011) J Vet Intern Med , vol.25 , pp. 1391-1397
    • Archer, T.M.1    Fellman, C.L.2    Stokes, J.V.3
  • 12
    • 79952184882 scopus 로고    scopus 로고
    • Cyclosporine A affects the in vitro expression of T cell activation-related molecules and cytokines in dogs
    • Epub 2010 Dec 4
    • Fellman CL, Stokes JV, Archer TM, Pinchuk LM, Lunsford KV, Mackin AJ. Cyclosporine A affects the in vitro expression of T cell activation-related molecules and cytokines in dogs. Vet Immunol Immunopathol 2011;140:175-180. Epub 2010 Dec 4.
    • (2011) Vet Immunol Immunopathol , vol.140 , pp. 175-180
    • Fellman, C.L.1    Stokes, J.V.2    Archer, T.M.3    Pinchuk, L.M.4    Lunsford, K.V.5    McKin, A.J.6
  • 13
    • 0032821587 scopus 로고    scopus 로고
    • Antigen specificity in canine autoimmune haemolytic anaemia
    • Day MJ. Antigen specificity in canine autoimmune haemolytic anaemia. Vet Immunol Immunopathol 1999;69:215-224.
    • (1999) Vet Immunol Immunopathol , vol.69 , pp. 215-224
    • Day, M.J.1
  • 15
    • 0029955541 scopus 로고    scopus 로고
    • Studies of platelet-bound and serum platelet-bindable immunoglobulins in dogs with idiopathic thrombocytopenic purpura
    • Lewis DC, Meyers KM. Studies of platelet-bound and serum platelet-bindable immunoglobulins in dogs with idiopathic thrombocytopenic purpura. Exp Hematol 1996;24:696-701.
    • (1996) Exp Hematol , vol.24 , pp. 696-701
    • Lewis, D.C.1    Meyers, K.M.2
  • 16
    • 34249299785 scopus 로고    scopus 로고
    • Canine immune-mediated hemolytic anemia: Treatment and prognosis
    • Balch A, Mackin A. Canine immune-mediated hemolytic anemia: Treatment and prognosis. Compend Contin Educ Vet 2007;29: 230-238.
    • (2007) Compend Contin Educ Vet , vol.29 , pp. 230-238
    • Balch, A.1    McKin, A.2
  • 17
    • 79953164263 scopus 로고    scopus 로고
    • The kaleidoscope of glucocorticoid effects on immune system
    • Zen M, Canova M, Campana C, et al. The kaleidoscope of glucocorticoid effects on immune system. Autoimmun Rev 2011;10:305-310.
    • (2011) Autoimmun Rev , vol.10 , pp. 305-310
    • Zen, M.1    Canova, M.2    Campana, C.3
  • 18
    • 0033347284 scopus 로고    scopus 로고
    • Wide variation in lymphocyte steroid sensitivity among healthy human volunteers
    • Hearing SD, Norman M, Smyth C, Foy C, Dayan CM. Wide variation in lymphocyte steroid sensitivity among healthy human volunteers. J Clin Endocrinol Metab 1999;84:4149-4154.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4149-4154
    • Hearing, S.D.1    Norman, M.2    Smyth, C.3    Foy, C.4    Dayan, C.M.5
  • 19
    • 84865490712 scopus 로고    scopus 로고
    • Current concepts in glucocorticoid resistance
    • Yang N, Ray DW, Matthews LC. Current concepts in glucocorticoid resistance. Steroids 2012;77:1041-1049.
    • (2012) Steroids , vol.77 , pp. 1041-1049
    • Yang, N.1    Ray, D.W.2    Matthews, L.C.3
  • 20
    • 68149157318 scopus 로고    scopus 로고
    • Treatment of Evans' syndrome with human intravenous immunoglobulin and leflunomide in a diabetic dog
    • Bianco D, Hardy RM. Treatment of Evans' syndrome with human intravenous immunoglobulin and leflunomide in a diabetic dog. J Am Anim Hosp Assoc 2009;45:147-150.
    • (2009) J Am Anim Hosp Assoc , vol.45 , pp. 147-150
    • Bianco, D.1    Hardy, R.M.2
  • 21
    • 76349118744 scopus 로고    scopus 로고
    • Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008)
    • Colopy SA, Baker TA, Muir P. Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008). J Am Vet Med Assoc 2010;236:312-318.
    • (2010) J Am Vet Med Assoc , vol.236 , pp. 312-318
    • Colopy, S.A.1    Baker, T.A.2    Muir, P.3
  • 22
    • 0032428534 scopus 로고    scopus 로고
    • Leflunomide effectively treats naturally occurring immune-mediated and inflammatory diseases of dogs that are unresponsive to conventional therapy
    • Gregory CR, Stewart A, Sturges B, et al. Leflunomide effectively treats naturally occurring immune-mediated and inflammatory diseases of dogs that are unresponsive to conventional therapy. Transplant Proc 1998;30:4143-4148.
    • (1998) Transplant Proc , vol.30 , pp. 4143-4148
    • Gregory, C.R.1    Stewart, A.2    Sturges, B.3
  • 23
    • 79953875979 scopus 로고    scopus 로고
    • Lack of evidence of a beneficial effect of azathioprine in dogs treated with prednisolone for idiopathic immune-mediated hemolytic anemia: A retrospective cohort study
    • Piek CJ, van Spil WE, Junius G, Dekker A. Lack of evidence of a beneficial effect of azathioprine in dogs treated with prednisolone for idiopathic immune-mediated hemolytic anemia: A retrospective cohort study. BMC Vet Res 2011;7:1-9.
    • (2011) BMC Vet Res , vol.7 , pp. 1-9
    • Piek, C.J.1    van Spil, W.E.2    Junius, G.3    Dekker, A.4
  • 24
    • 0034098326 scopus 로고    scopus 로고
    • Immunosuppressive drugs: The first 50 years and a glance forward
    • Allison AC. Immunosuppressive drugs: The first 50 years and a glance forward. Immunopharmacology 2000;47:63-83.
    • (2000) Immunopharmacology , vol.47 , pp. 63-83
    • Allison, A.C.1
  • 25
    • 0033894545 scopus 로고    scopus 로고
    • Comparison of the in vitro antiproliferative effects of five immunosuppressive drugs on lymphocytes in whole blood from cats
    • Kyles AE, Gregory CR, Craigmill AL. Comparison of the in vitro antiproliferative effects of five immunosuppressive drugs on lymphocytes in whole blood from cats. Am J Vet Res 2000;61:906-909.
    • (2000) Am J Vet Res , vol.61 , pp. 906-909
    • Kyles, A.E.1    Gregory, C.R.2    Craigmill, A.L.3
  • 26
    • 65849325334 scopus 로고    scopus 로고
    • Synthesis and immunomodulation of human lymphocyte proliferation and cytokine (interferon-gamma) production of four novel malonitrilamides
    • Hadizadeh F, Moallem SA, Jaafari MR, et al. Synthesis and immunomodulation of human lymphocyte proliferation and cytokine (interferon-gamma) production of four novel malonitrilamides. Chem Biol Drug Des 2009;73:668-673.
    • (2009) Chem Biol Drug Des , vol.73 , pp. 668-673
    • Hadizadeh, F.1    Moallem, S.A.2    Jaafari, M.R.3
  • 27
    • 0023104716 scopus 로고
    • Response to isoantigens and mitogens in the cat: Effects of cyclosporin A
    • Gregory CR, Taylor NJ, Willits NH, Theilen GH. Response to isoantigens and mitogens in the cat: effects of cyclosporin A. Am J Vet Res 1987;48:126-130.
    • (1987) Am J Vet Res , vol.48 , pp. 126-130
    • Gregory, C.R.1    Taylor, N.J.2    Willits, N.H.3    Theilen, G.H.4
  • 28
    • 0026576791 scopus 로고
    • A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs
    • Takaori K, Nio Y, Inoue K, et al. A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs. Biotherapy 1992;4: 129-137.
    • (1992) Biotherapy , vol.4 , pp. 129-137
    • Takaori, K.1    Nio, Y.2    Inoue, K.3
  • 29
    • 77956283521 scopus 로고    scopus 로고
    • Lack of effects on lymphocyte function from chronic topical ocular cyclosporine medication: A prospective study
    • Williams DL. Lack of effects on lymphocyte function from chronic topical ocular cyclosporine medication: A prospective study. Vet Ophthalmol 2010;13:315-320.
    • (2010) Vet Ophthalmol , vol.13 , pp. 315-320
    • Williams, D.L.1
  • 30
    • 77953779485 scopus 로고    scopus 로고
    • Pharmacokinetics & pharmacodynamics: Rational dosing & the time course of drug action
    • In: Katzung BG, Masters SB, Trevor AJ, eds, New York, New York: McGraw-Hill Companies
    • Holford NHG. Pharmacokinetics & pharmacodynamics: Rational dosing & the time course of drug action. In: Katzung BG, Masters SB, Trevor AJ, eds. Basic and Clinical Pharmacology. New York, New York: McGraw-Hill Companies, 2012:37-51.
    • (2012) Basic and Clinical Pharmacology , pp. 37-51
    • Holford, N.H.G.1
  • 31
    • 0028289245 scopus 로고
    • The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: Comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma
    • Haczku A, Alexander A, Brown P, et al. The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: Comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma. J Allergy Clin Immunol 1994;93:510-519.
    • (1994) J Allergy Clin Immunol , vol.93 , pp. 510-519
    • Haczku, A.1    Alexander, A.2    Brown, P.3
  • 32
    • 0032795775 scopus 로고    scopus 로고
    • Predicting therapeutic outcome in severe ulcerative colitis by measuring in vitro steroid sensitivity of proliferating peripheral blood lymphocytes
    • Hearing SD, Norman M, Probert CS, Haslam N, Dayan CM. Predicting therapeutic outcome in severe ulcerative colitis by measuring in vitro steroid sensitivity of proliferating peripheral blood lymphocytes. Gut 1999;45:382-388.
    • (1999) Gut , vol.45 , pp. 382-388
    • Hearing, S.D.1    Norman, M.2    Probert, C.S.3    Haslam, N.4    Dayan, C.M.5
  • 33
    • 77958613310 scopus 로고    scopus 로고
    • A novel NF-kB inhibitor improves glucocorticoid sensitivity of canine neoplastic lymphoid cells by up-regulating expression of glucocorticoid receptors
    • Matsuda A, Tanaka K, Muto S, et al. A novel NF-kB inhibitor improves glucocorticoid sensitivity of canine neoplastic lymphoid cells by up-regulating expression of glucocorticoid receptors. Res Vet Sci 2010;89:378-382.
    • (2010) Res Vet Sci , vol.89 , pp. 378-382
    • Matsuda, A.1    Tanaka, K.2    Muto, S.3
  • 34
    • 81555204431 scopus 로고    scopus 로고
    • Glucocorticoid sensitivity depends on expression levels of glucocorticoid receptors in canine neoplastic mast cells
    • Epub 2011 Aug 26
    • Matsuda A, Tanaka A, Amagai Y, et al. Glucocorticoid sensitivity depends on expression levels of glucocorticoid receptors in canine neoplastic mast cells. Vet Immunol Immunopathol 2011;144:321-328. Epub 2011 Aug 26.
    • (2011) Vet Immunol Immunopathol , vol.144 , pp. 321-328
    • Matsuda, A.1    Tanaka, A.2    Amagai, Y.3


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