Nuclear MEK1 sequesters PPARγ and bisects MEK1/ERK signaling: A non-canonical pathway of retinoic acid inhibition of adipocyte differentiation

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Dave, Sandeep ^a   Nanduri, Ravikanth ^a   Dkhar, Hedwin Kitdorlang ^a   Bhagyaraj, Ella ^a   Rao, Alka ^a   Gupta, Pawan ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EXPORTIN 1; HISTONE DEACETYLASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; N ETHYLMALEIMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOIC ACID; S NITROSOGLUTATHIONE; VIMENTIN; CELL RECEPTOR; EXPORTIN 1 PROTEIN; KARYOPHERIN; MAP2K1 PROTEIN, MOUSE;

ACYLATION; ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; INHIBITION KINETICS; METABOLIC REGULATION; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; NUCLEOTIDE SEQUENCE; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN RETINOYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION; 3T3 CELL LINE; ANIMAL; CYTOLOGY; GENETICS; METABOLISM; PHYSIOLOGY;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CELL DIFFERENTIATION; KARYOPHERINS; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MICE; PPAR GAMMA; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRETINOIN;

EID: 84903525561     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100862     Document Type: Article

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