Nitric oxide mediates cell aggregation and mesenchymal to epithelial transition in anoikis-resistant lung cancer cells

Molecular and Cellular Biochemistry

Volumn 393, Issue 1-2, 2014, Pages 237-245

  Powan, Phattrakorn ^a   Chanvorachote, Pithi ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Aggregation; Anoikis resistance; Lung cancer cells; Metastasis; Nitric oxide

Indexed keywords

LIPOCORTIN 5; NERVE CELL ADHESION MOLECULE; NITRIC OXIDE; NITRIC OXIDE DONOR; UVOMORULIN; VIMENTIN; CADHERIN;

ANOIKIS; APOPTOSIS; ARTICLE; CELL AGGREGATION; CELL INTERACTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; LUNG CANCER; LUNG CANCER CELL LINE; METASTASIS; UPREGULATION; WESTERN BLOTTING; GENETICS; LUNG NEOPLASMS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANOIKIS; CADHERINS; CELL AGGREGATION; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; LUNG NEOPLASMS; NEOPLASM METASTASIS; NITRIC OXIDE;

EID: 84903459357     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2066-7     Document Type: Article

References (30)

1. Glinsky VV, Glinsky GV, Glinskii OV, Huxley VH, Turk JR, Mossine VV, Deutscher SL, Pienta KJ, Quinn TP (2003) Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium1.CancerRes 63:3805-3811 (Pubitemid 36793070)
2. Saiki I, Naito S, Yoneda J, Azuma I, Price JE, Fidler IJ (1991) Characterization of the invasive and metastatic phenotype in human renal cell carcinoma. Clin Exp Metastasis 9:551-566
3. Glinsky GV, Glinsky VV (1996) Apoptosis and metastasis: a superior resistance of metastatic cancer cells to programmed cell death. Cancer Lett 101:43-51 (Pubitemid 26060191)
4. Topal B, Roskams T, Fevery J, Penninckx FJ (2003) Aggregated colon cancer cells have a higher metastatic efficiency in the liver compared with nonaggregated cells: an experimental study. Surg Res 112:31-37 (Pubitemid 36836176)
5. Fidler IJ (1975) The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. Eur J Cancer 9:223-227
6. Guadamillas MC, Cerezo A, Del Pozo MA (2011) Overcoming anoikis-pathways to anchorage-independent growth in cancer. J Cell Sci 124(Pt 19):3189-3197. doi:10.1242/jcs.072165
7. Simpson CD, Anyiwe K, Schimmer AD (2008) Anoikis resistance and tumor metastasis. Cancer Lett 272:177-185. doi:10.1016/j.canlet.2008.05.029
8. Chunhacha P, Pongrakhananon V, Rojanasakul Y, Chanvorachote P (2012) Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells. Am J Physiol Cell Physiol 302:1284-1292
9. Ma XK, Wang L, Li Y, Yang XM, Zhao P, Tang H, Zhu P, Li L, Chen ZN (2010) HAb18G/CD147 cell-cell contacts confer resistance of a HEK293 subpopulation to anoikis in an E-cadherin-dependent manner. BMC Cell Biol 11:27
10. Shen X, Kramer RH (2004) Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor. Am J Pathol 165:1315-1329 (Pubitemid 39297736)
11. Halim H, Luanpitpong S, Chanvorachote P (2012) Acquisition of anoikis resistance up-regulates caveolin-1 expression in human non-small cell lung cancer cells. Anticancer Res 32:1649-1658
12. Zhao M, Gao Y, Wang L, Liu S, Han B, Ma L, Ling Y, Mao S, Wang X (2013) Overexpression of integrin-linked kinase promotes lung cancer cell migration and invasion via NF-κB-mediated upregulation of matrix metalloproteinase-9. Int J Med Sci 10:995-1002. doi:10.7150/ijms.5963
13. Thiery JP (2002) Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2:442-454
14. Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139:871-890
15. Jia J, Zhang W, Liu JY, Chen G, Liu H, Zhong HY, Liu B, Cai Y, Zhang JL, Zhao YF (2012) Epithelial mesenchymal transition is required for acquisition of anoikis resistance and metastatic potential in adenoid cystic carcinoma. PLoS One 7:e51549. doi:10.1371/journal.pone.0051549
16. Reddy P, Liu L, Ren C, Lindgren P, Boman K, Shen Y, Lundin E, Ottander U, Rytinki M, Liu K (2005) Formation of E-cadherin-mediated cell-cell adhesion activates AKT and mitogen activated protein kinase via phosphatidylinositol 3 kinase and ligand-independent activation of epidermal growth factor receptor in ovarian cancer cells. Mol Endocrinol 19:2564-2578 (Pubitemid 41362669)
17. Alpaugh ML, Tomlinson JS, Kasraeian S, Barsky SH (2002) Cooperative role of E-cadherin and sialyl-Lewis X/A-deficient MUC1 in the passive dissemination of tumor emboli in inflammatory breast carcinoma. Oncogene 21:3631-3643 (Pubitemid 34587695)
18. Auersperg N, Pan J, Grove BD, Peterson T, Fisher J, Maines-Bandiera S, Somasiri A, Roskelley CD (1999) E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium. Proc Natl Acad Sci USA 96:6249-6254 (Pubitemid 29256651)
19. Manda G, Nechifor MT, Neagu T-M (2009) Reactive oxygen species, cancer and anti-cancer therapies. Curr Chem Biol 3:22-46
20. Keibel A, Vb Singh, Sharma MC (2009) Inflammation, microenvironment, and the immune system in cancer progression. Curr Pharm Des 15:1949-1955
21. Lala PK, Chakraborty C (2001) Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol 3:149-156 (Pubitemid 33585926)
22. Masri FA, Comhair SAA, Koeck T, Xu W, Janocha A, Ghosh S, Dweik RA, Golish J, Kinter M, Stuehr DJ, Erzurum SC, Aulak KS (2005) Abnormalities in nitric oxide and its derivatives in lung cancer. Am J Respir Crit Care Med 172:597-605. doi:10.1164/rccm.200411-1523OC (Pubitemid 41232971)
23. Esme H, Cemek M, Sezer M, Saglam H, Demir A, Melek H, Unlu M (2008) High levels of oxidative stress in patients with advanced lung cancer. Respirology 13:112-116
24. Chanvorachote P, Nimmannit U, Lu Y, Talbott S, Jiang BH, Rojanasakul Y (2009) Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1. J Biol Chem 284:28476-28484
25. Chanvorachote P, Nimmannit U, Stehlik C, Wang L, Jiang BH, Ongpipatanakul B, Rojanasakul Y (2006) Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination. Cancer Res 66:6353-6360
26. Chanvorachote P, Nimmannit U, Wang L, Stehlik C, Lu B, Azad N, Rojanasakul Y (2005) Nitric oxide negatively regulates Fasinduced apoptosis through inhibition of ubiquitin-proteasome-mediated degradation of FLICE inhibitory protein. J Biol Chem 280:42044-42050 (Pubitemid 43023173)
27. Sanuphan A, Chunhacha P, Pongrakhananon V, Chanvorachote P (2013) Long-term nitric oxide exposure enhances lung cancer cell migration. Biomed Res Int 2013:186972. doi: 10.1155/2013/186972
28. Moncada S, Higgs A (1993) The L-arginine-nitric oxide pathway. N Engl J Med 329:2002-2012 (Pubitemid 24015045)
29. Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646-6474. doi:10.1016/j.cell.2011.02.013
30. Chunhacha P, Sriuranpong V, Chanvorachote P (2013) Epithelial-mesenchymal transition mediates anoikis resistance and enhances invasion in pleural effusion-derived human lung cancer cells. Oncol Lett 5:1043-1047