Graphene oxide attenuates Th2-type immune responses, but augments airway remodeling and hyperresponsiveness in a murine model of asthma

ACS Nano

Volumn 8, Issue 6, 2014, Pages 5585-5599

  Shurin, Michael R ^a   Yanamala, Naveena ^b   Kisin, Elena R ^b   Tkach, Alexey V ^b   Shurin, Galina V ^a   Murray, Ashley R ^b   Leonard, Howard D ^b   Reynolds, Jeffrey S ^b   Gutkin, Dmirtiy W ^a   Star, Alexander ^c   Fadeel, Bengt ^c   Savolainen, Kai ^d   Kagan, Valerian E ^c   Shvedova, Anna A ^b,e  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^e WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chitinases; IgE independent AHR; macrophage activation; Th2 responses

Indexed keywords

GRAPHENE; IMMUNE SYSTEM; INDUSTRIAL APPLICATIONS; MACROPHAGES; MAMMALS;

AIRWAY REMODELING; CHITINASES; IGE-INDEPENDENT AHR; IMMUNE RESPONSE; MACROPHAGE ACTIVATION; NANOPARTICLE (NPS); PHYSICOCHEMICAL PROPERTY; TH2 RESPONSES;

PULMONARY DISEASES;

CHITINASE; GRAPHITE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; NANOPARTICLE; OXIDE;

AIRWAY REMODELING; ANIMAL; BINDING SITE; BRONCHOALVEOLAR LAVAGE FLUID; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; IMMUNE SYSTEM; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; METABOLISM; MOUSE; NANOTECHNOLOGY; PROCEDURES; TH2 CELL;

AIRWAY REMODELING; ANIMALS; BINDING SITES; BRONCHOALVEOLAR LAVAGE FLUID; CHITINASE; DISEASE MODELS, ANIMAL; GRAPHITE; IMMUNE SYSTEM; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFLAMMATION; INTERLEUKIN-13; INTERLEUKIN-4; INTERLEUKIN-5; MACROPHAGES; MICE; NANOPARTICLES; NANOTECHNOLOGY; OXIDES; TH2 CELLS;

EID: 84903455887     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn406454u     Document Type: Article

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