Protective effect of pioglitazone, a PPARγ agonist against acetaminophen-induced hepatotoxicity in rats

Molecular and Cellular Biochemistry

Volumn 393, Issue 1-2, 2014, Pages 223-228

  Gupta, Gaurav ^a   Krishna, Gopala ^b   Chellappan, Dinesh Kumar ^a   Gubbiyappa, Kumar Shiva ^a   Candasamy, Mayuren ^a   Dua, Kamal ^c  

^a INTERNATIONAL MEDICAL UNIVERSITY   (Malaysia)

^b AM Reddy Memorial College of Pharmacy   (India)

^c UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Acetaminophen; Hepatotoxicity; Liver; Pioglitazone; PPAR gamma agonist

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALPHA FETOPROTEIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CATALASE; FREE RADICAL; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; PARACETAMOL; PIOGLITAZONE; PROTEIN; SUPEROXIDE DISMUTASE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ALPHA FETOPROTEIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; SPRAGUE DAWLEY RAT; TREATMENT DURATION; ANIMAL; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; METABOLISM; PATHOLOGY;

ACETAMINOPHEN; ANIMALS; DRUG-INDUCED LIVER INJURY; LIPID PEROXIDATION; PPAR GAMMA; RATS; THIAZOLIDINEDIONES;

EID: 84903436909     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2064-9     Document Type: Article

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