Accumulation of heptaprenyl diphosphate sensitizes Bacillus subtilis to bacitracin: Implications for the mechanism of resistance mediated by the BceAB transporter

Molecular Microbiology

Volumn 93, Issue 1, 2014, Pages 37-49

  Kingston, Anthony W ^a   Zhao, Heng ^a   Cook, Gregory M ^b   Helmann, John D ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDROXY 2 NAPHTHOATE; 2 NAPHTHOIC ACID; ABC TRANSPORTER; BACITRACIN; BCEAB TRANSPORTER; BCRC PHOSPHATASE; HEPTAPRENYL DIPHOSPHATE; ISOPRENOID; PHOSPHATASE; SYNTHETASE; UNCLASSIFIED DRUG; UNDECAPRENYL PYROPHOSPHATE SYNTHETASE 1; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; HEPTAPRENYL DIPHOSPHATE C35; ISOPRENOID PHOSPHATE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; BACTERIUM MUTANT; BIOACCUMULATION; BIOSYNTHESIS; CELL DENSITY; CONTROLLED STUDY; DISK DIFFUSION; DRUG BINDING; DRUG SENSITIZATION; EPISTASIS; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE INACTIVATION; HEPT GENE; MEMBRANE TRANSPORT; MENA GENE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OPERON; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSMEMBRANE RELOCATION; UPPS1 GENE; UPREGULATION; YTPA GENE; YTPB GENE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; MUTATION; PROTEIN TRANSPORT;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACITRACIN; BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; MUTATION; POLYISOPRENYL PHOSPHATES; PROTEIN TRANSPORT;

EID: 84903398330     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12637     Document Type: Article

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