메뉴 건너뛰기




Volumn 9, Issue 6, 2014, Pages

Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; CD103 ANTIGEN; MUCIN 2; ALPHA E INTEGRINS; ALPHA INTEGRIN; CD14 ANTIGEN; LEUKOCYTE ANTIGEN;

EID: 84903397380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100217     Document Type: Article
Times cited : (89)

References (43)
  • 1
    • 54449083567 scopus 로고    scopus 로고
    • The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
    • Johansson MEV, Phillipson M, Petersson J, Velcich A, Holm L, et al. (2008) The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci USA. 105: 15064-15069.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15064-15069
    • Johansson, M.E.V.1    Phillipson, M.2    Petersson, J.3    Velcich, A.4    Holm, L.5
  • 2
    • 79952748335 scopus 로고    scopus 로고
    • Colloquium Paper: The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions
    • Johansson MEV, Larsson JMH, Hansson GC (2011) Colloquium Paper: The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc Natl Acad Sci USA. 108: 4659-4665.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4659-4665
    • Johansson, M.E.V.1    Larsson, J.M.H.2    Hansson, G.C.3
  • 3
    • 80054122238 scopus 로고    scopus 로고
    • The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine
    • Vaishnava S, Yamamoto M, Severson KM, Ruhn KA, Yu X, et al. (2011) The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science. 334: 255-258.
    • (2011) Science , vol.334 , pp. 255-258
    • Vaishnava, S.1    Yamamoto, M.2    Severson, K.M.3    Ruhn, K.A.4    Yu, X.5
  • 4
    • 84872094450 scopus 로고    scopus 로고
    • The goblet cell: A key player in ischaemia-reperfusion injury
    • Johansson MEV, Hansson GC (2013) The goblet cell: a key player in ischaemia-reperfusion injury. Gut. 62: 188-189.
    • (2013) Gut , vol.62 , pp. 188-189
    • Johansson, M.E.V.1    Hansson, G.C.2
  • 5
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Abraham C, Cho JH (2009) Inflammatory bowel disease. N Engl J Med. 361: 2066-2078.
    • (2009) N Engl J Med , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 7
    • 79959216005 scopus 로고    scopus 로고
    • Genetics and pathogenesis of inflammatory bowel disease
    • Khor B, Gardet A, Xavier RJ (2011) Genetics and pathogenesis of inflammatory bowel disease. Nature. 474: 307-317.
    • (2011) Nature , vol.474 , pp. 307-317
    • Khor, B.1    Gardet, A.2    Xavier, R.J.3
  • 8
    • 84891736162 scopus 로고    scopus 로고
    • Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
    • Johansson MEV, Gustafsson JK, Holmén-Larsson J, Jabbar KS, Xia L, et al. (2014) Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis. Gut. 63: 281-291.
    • (2014) Gut , vol.63 , pp. 281-291
    • Johansson, M.E.V.1    Gustafsson, J.K.2    Holmén-Larsson, J.3    Jabbar, K.S.4    Xia, L.5
  • 9
    • 70649103789 scopus 로고    scopus 로고
    • Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
    • UK IBD Genetics Consortium
    • UK IBD Genetics Consortium, Barrett JC, Lee JC, Lees CW, Prescott NJ, et al. (2009) Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet. 41: 1330-1334.
    • (2009) Nat Genet , vol.41 , pp. 1330-1334
    • Barrett, J.C.1    Lee, J.C.2    Lees, C.W.3    Prescott, N.J.4
  • 11
    • 84880653498 scopus 로고    scopus 로고
    • IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells
    • Hasnain SZ, Tauro S, Das I, Tong H, Chen AC-H, et al. (2013) IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells. Gastroenterology. 144: 357-368.e359.
    • (2013) Gastroenterology , vol.144
    • Hasnain, S.Z.1    Tauro, S.2    Das, I.3    Tong, H.4    Chen, A.C.-H.5
  • 12
  • 13
    • 10944253153 scopus 로고    scopus 로고
    • Oxazolone-induced colitis in BALB/C mice: A new method to evaluate the efficacy of therapeutic agents for ulcerative colitis
    • DOI 10.1254/jphs.FP0040214
    • Kojima R, Kuroda S, Ohkishi T, Nakamaru K, Hatakeyama S (2004) Oxazolone-induced colitis in BALB/C mice: a new method to evaluate the efficacy of therapeutic agents for ulcerative colitis. J Pharmacol Sci. 96: 307-313. (Pubitemid 40013340)
    • (2004) Journal of Pharmacological Sciences , vol.96 , Issue.3 , pp. 307-313
    • Kojima, R.1    Kuroda, S.2    Ohkishi, T.3    Nakamaru, K.4    Hatakeyama, S.5
  • 15
    • 67650314612 scopus 로고    scopus 로고
    • Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages
    • Rupp J, Pfleiderer L, Jugert C, Moeller S, Klinger M, et al. (2009) Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages. PLoS ONE. 4: e6020.
    • (2009) PLoS ONE , vol.4
    • Rupp, J.1    Pfleiderer, L.2    Jugert, C.3    Moeller, S.4    Klinger, M.5
  • 16
    • 85077257460 scopus 로고    scopus 로고
    • Relative quantification
    • Dorak, MT, editor. New York: Taylor and Francis
    • Pfaffl MW (2006) Relative quantification. In: Dorak, MT, editor. Real-time PCR. New York: Taylor and Francis. 63-82.
    • (2006) Real-time PCR , pp. 63-82
    • Pfaffl, M.W.1
  • 17
    • 0242490269 scopus 로고    scopus 로고
    • Bacterial colonization leads to the colonic secretion of RELMb/FIZZ2, a novel goblet cell-specific protein
    • HE W, Wang M-L, Jiang H-Q, Steppan CM, Shin ME, et al. (2003) Bacterial colonization leads to the colonic secretion of RELMb/FIZZ2, a novel goblet cell-specific protein. YGAST 125: 1388-1397.
    • (2003) YGAST , vol.125 , pp. 1388-1397
    • He, W.1    Wang, M.-L.2    Jiang, H.-Q.3    Steppan, C.M.4    Shin, M.E.5
  • 18
    • 34247561732 scopus 로고    scopus 로고
    • Monocyte recruitment, activation, and function in the gut-associated lymphoid tissue during oral Salmonella infection
    • Rydström A, Wick MJ (2007) Monocyte recruitment, activation, and function in the gut-associated lymphoid tissue during oral Salmonella infection. J Immunol 178: 5789-5801. (Pubitemid 46674376)
    • (2007) Journal of Immunology , vol.178 , Issue.9 , pp. 5789-5801
    • Rydstrom, A.1    Wick, M.J.2
  • 19
    • 33747050143 scopus 로고    scopus 로고
    • The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients
    • DOI 10.1099/jmm.0.46498-0
    • Bibiloni R, Mangold M, Madsen KL, Fedorak RN, Tannock GW (2006) The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients. J Med Microbiol. 55: 1141-1149. (Pubitemid 44215574)
    • (2006) Journal of Medical Microbiology , vol.55 , Issue.8 , pp. 1141-1149
    • Bibiloni, R.1    Mangold, M.2    Madsen, K.L.3    Fedorak, R.N.4    Tannock, G.W.5
  • 20
    • 79960513242 scopus 로고    scopus 로고
    • Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization
    • Denning TL, Norris BA, Medina-Contreras O, Manicassamy S, Geem D, et al. (2011) Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization. J Immunol. 187: 733-747.
    • (2011) J Immunol , vol.187 , pp. 733-747
    • Denning, T.L.1    Norris, B.A.2    Medina-Contreras, O.3    Manicassamy, S.4    Geem, D.5
  • 21
    • 80053156515 scopus 로고    scopus 로고
    • Dendritic cell and macrophage heterogeneity in vitro & in vivo
    • Hashimoto D, Miller J, Merad M (2011) Dendritic cell and macrophage heterogeneity in vitro & in vivo. Immunity. 35: 323-335.
    • (2011) Immunity , vol.35 , pp. 323-335
    • Hashimoto, D.1    Miller, J.2    Merad, M.3
  • 23
    • 84856815290 scopus 로고    scopus 로고
    • hi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon
    • hi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J Exp Med. 209: 139-155.
    • (2012) J Exp Med , vol.209 , pp. 139-155
    • Rivollier, A.1    He, J.2    Kole, A.3    Valatas, V.4    Kelsall, B.L.5
  • 24
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • DOI 10.1038/nature06005, PII NATURE06005
    • Xavier RJ, Podolsky DK (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature. 448: 427-434. (Pubitemid 47123518)
    • (2007) Nature , vol.448 , Issue.7152 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 25
    • 70349484242 scopus 로고    scopus 로고
    • Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse
    • Gisbert JP, Bermejo F, Pérez-Calle J-L, Taxonera C, Vera I, et al. (2009) Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse. Inflamm Bowel Dis. 15: 1190-1198.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1190-1198
    • Gisbert, J.P.1    Bermejo, F.2    Pérez-Calle, J.-L.3    Taxonera, C.4    Vera, I.5
  • 27
    • 79955106916 scopus 로고    scopus 로고
    • An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity
    • Eri RD, Adams RJ, Tran TV, Tong H, Das I, et al. (2010) An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity. Mucosal Immunol. 4: 354-364.
    • (2010) Mucosal Immunol , vol.4 , pp. 354-364
    • Eri, R.D.1    Adams, R.J.2    Tran, T.V.3    Tong, H.4    Das, I.5
  • 28
    • 79951790272 scopus 로고    scopus 로고
    • CX3CR1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions
    • Weber B, Saurer L, Schenk M, Dickgreber N, Mueller C (2011) CX3CR1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions. Eur J Immunol. 41: 773-779.
    • (2011) Eur J Immunol , vol.41 , pp. 773-779
    • Weber, B.1    Saurer, L.2    Schenk, M.3    Dickgreber, N.4    Mueller, C.5
  • 29
    • 79953307656 scopus 로고    scopus 로고
    • Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice
    • Fu J, Wei B, Wen T, Johansson MEV, Liu X, et al. (2011) Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. J Clin Invest 121: 1657-1666.
    • (2011) J Clin Invest , vol.121 , pp. 1657-1666
    • Fu, J.1    Wei, B.2    Wen, T.3    Johansson, M.E.V.4    Liu, X.5
  • 30
    • 77951934151 scopus 로고    scopus 로고
    • E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis
    • Siddiqui KRR, Laffont S, Powrie F (2010) E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis. Immunity. 32: 557-567.
    • (2010) Immunity , vol.32 , pp. 557-567
    • Siddiqui, K.R.R.1    Laffont, S.2    Powrie, F.3
  • 31
    • 77953644572 scopus 로고    scopus 로고
    • An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation
    • Platt AM, Bain CC, Bordon Y, Sester DP, Mowat AM (2010) An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation. The J. Immunol. 184: 6843-6854.
    • (2010) The J. Immunol. , vol.184 , pp. 6843-6854
    • Platt, A.M.1    Bain, C.C.2    Bordon, Y.3    Sester, D.P.4    Mowat, A.M.5
  • 32
    • 70049099836 scopus 로고    scopus 로고
    • Intestinal lamina propria dendritic cell subsets have different origin and functions
    • Varol C, Vallon-Eberhard A, Elinav E, Aychek T, Shapira Y, et al. (2009) Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity. 31: 502-512.
    • (2009) Immunity , vol.31 , pp. 502-512
    • Varol, C.1    Vallon-Eberhard, A.2    Elinav, E.3    Aychek, T.4    Shapira, Y.5
  • 35
    • 84871307366 scopus 로고    scopus 로고
    • CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis
    • Tamoutounour S, Henri S, Lelouard H, de Bovis B, de Haar C, et al. (2012) CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. Eur J Immunol. 42: 3150-3166.
    • (2012) Eur J Immunol , vol.42 , pp. 3150-3166
    • Tamoutounour, S.1    Henri, S.2    Lelouard, H.3    De Bovis, B.4    De Haar, C.5
  • 37
    • 84880842575 scopus 로고    scopus 로고
    • Lesional accumulation of CD163-expressing cells in the gut of patients with inflammatory bowel disease
    • Franzè E, Caruso R, Stolfi C, Sarra M, Cupi ML, et al. (2013) Lesional accumulation of CD163-expressing cells in the gut of patients with inflammatory bowel disease. PLoS ONE. 8: e69839.
    • (2013) PLoS ONE , vol.8
    • Franzè, E.1    Caruso, R.2    Stolfi, C.3    Sarra, M.4    Cupi, M.L.5
  • 38
    • 77951737056 scopus 로고    scopus 로고
    • Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction
    • Matteoli G, Mazzini E, Iliev ID, Mileti E, Fallarino F, et al. (2010) Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction. Gut. 59: 595-604.
    • (2010) Gut , vol.59 , pp. 595-604
    • Matteoli, G.1    Mazzini, E.2    Iliev, I.D.3    Mileti, E.4    Fallarino, F.5
  • 39
    • 70049103635 scopus 로고    scopus 로고
    • Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells
    • Iliev ID, Spadoni I, Mileti E, Matteoli G, Sonzogni A, et al. (2009) Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells. Gut. 58: 1481-1489.
    • (2009) Gut , vol.58 , pp. 1481-1489
    • Iliev, I.D.1    Spadoni, I.2    Mileti, E.3    Matteoli, G.4    Sonzogni, A.5
  • 40
    • 51049092467 scopus 로고    scopus 로고
    • + dendritic cells display unique functional properties that are conserved between mice and humans
    • + dendritic cells display unique functional properties that are conserved between mice and humans. J Exp Med. 205: 2139-2149.
    • (2008) J Exp Med , vol.205 , pp. 2139-2149
    • Jaensson, E.1    Uronen-Hansson, H.2    Pabst, O.3    Eksteen, B.4    Tian, J.5
  • 42
    • 77952794397 scopus 로고    scopus 로고
    • Securing the immune tightrope: Mononuclear phagocytes in the intestinal lamina propria
    • Varol C, Zigmond E, Jung S (2010) Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria. Nat Rev Immunol. 10: 415-426.
    • (2010) Nat Rev Immunol , vol.10 , pp. 415-426
    • Varol, C.1    Zigmond, E.2    Jung, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.