-
1
-
-
74849094402
-
Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: Results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry
-
10.1002/art.27227 [doi]
-
Hetland ML, Christensen IJ, Tarp U, Dreyer L, Hansen A, et al. (2010) Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry. Arthritis Rheum 62: 22-32. 10.1002/art.27227 [doi].
-
(2010)
Arthritis Rheum
, vol.62
, pp. 22-32
-
-
Hetland, M.L.1
Christensen, I.J.2
Tarp, U.3
Dreyer, L.4
Hansen, A.5
-
2
-
-
79957927386
-
Anti-TNF therapy: Safety aspects of taking the risk
-
10.1016/j.autrev.2011.04.010 [doi]
-
Rosenblum H, Amital H (2011) Anti-TNF therapy: safety aspects of taking the risk. Autoimmun Rev 10: 563-568. 10.1016/j.autrev.2011.04.010 [doi].
-
(2011)
Autoimmun Rev
, vol.10
, pp. 563-568
-
-
Rosenblum, H.1
Amital, H.2
-
3
-
-
82755184099
-
Optimising treatment in rheumatoid arthritis: A review of potential biological markers of response
-
10.1136/ard.2010.148015 [doi]
-
Emery P, Dorner T (2011) Optimising treatment in rheumatoid arthritis: a review of potential biological markers of response. Ann Rheum Dis 70: 2063-2070. 10.1136/ard.2010.148015 [doi].
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 2063-2070
-
-
Emery, P.1
Dorner, T.2
-
4
-
-
84858650504
-
Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis
-
10.1371/journal.pone.0033199 [doi];PONE-D-11-21951 [pii]
-
Toonen EJ, Gilissen C, Franke B, Kievit W, Eijsbouts AM, et al. (2012) Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis. PLoS One 7: e33199. 10.1371/journal.pone. 0033199 [doi];PONE-D-11-21951 [pii].
-
(2012)
PLoS One
, vol.7
-
-
Toonen, E.J.1
Gilissen, C.2
Franke, B.3
Kievit, W.4
Eijsbouts, A.M.5
-
5
-
-
77954241353
-
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy
-
10.1002/art.27457 [doi]
-
Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil AH, et al. (2010) Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy. Arthritis Rheum 62: 1849-1861. 10.1002/art.27457 [doi].
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1849-1861
-
-
Cui, J.1
Saevarsdottir, S.2
Thomson, B.3
Padyukov, L.4
Van Der Helm-Van Mil, A.H.5
-
6
-
-
84857721973
-
Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort
-
10.1002/art.33381 [doi]
-
Plant D, Prajapati R, Hyrich KL, Morgan AW, Wilson AG, et al. (2012) Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort. Arthritis Rheum 64: 665-670. 10.1002/art.33381 [doi].
-
(2012)
Arthritis Rheum
, vol.64
, pp. 665-670
-
-
Plant, D.1
Prajapati, R.2
Hyrich, K.L.3
Morgan, A.W.4
Wilson, A.G.5
-
7
-
-
84863817855
-
Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFalpha inhibitors in patients with rheumatoid arthritis
-
10.1097/FPC.0b013e3283544043 [doi]
-
Krintel SB, Palermo G, Johansen JS, Germer S, Essioux L, et al. (2012) Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFalpha inhibitors in patients with rheumatoid arthritis. Pharmacogenet Genomics 22: 577-589. 10.1097/FPC.0b013e3283544043 [doi].
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 577-589
-
-
Krintel, S.B.1
Palermo, G.2
Johansen, J.S.3
Germer, S.4
Essioux, L.5
-
8
-
-
84880133098
-
Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis
-
0: annrheumdis-2012-202405 [pii];10.1136/annrheumdis-2012-202405 [doi]
-
Umicevic MM, Cui J, Vermeulen SH, Stahl EA, Toonen EJ, et al. (2012) Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis. Ann Rheum Dis 0: 1-7. annrheumdis-2012-202405 [pii];10.1136/annrheumdis-2012-202405 [doi].
-
(2012)
Ann Rheum Dis
, pp. 1-7
-
-
Umicevic, M.M.1
Cui, J.2
Vermeulen, S.H.3
Stahl, E.A.4
Toonen, E.J.5
-
9
-
-
84899910966
-
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment
-
0: annrheumdis-2013-203276 [pii];10.1136/annrheumdis-2013-203276 [doi]
-
Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC, et al. (2013) Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment. Ann Rheum Dis 0: 1-9. annrheumdis-2013-203276 [pii];10.1136/annrheumdis-2013-203276 [doi].
-
(2013)
Ann Rheum Dis
, pp. 1-9
-
-
Mathews, R.J.1
Robinson, J.I.2
Battellino, M.3
Wong, C.4
Taylor, J.C.5
-
10
-
-
77955022748
-
Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways
-
ard.2009.117309 [pii]; 10.1136/ard.2009.117309 [doi]
-
Potter C, Cordell HJ, Barton A, Daly AK, Hyrich KL, et al. (2010) Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways. Ann Rheum Dis 69: 1315-1320. ard.2009.117309 [pii];10.1136/ard.2009.117309 [doi].
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1315-1320
-
-
Potter, C.1
Cordell, H.J.2
Barton, A.3
Daly, A.K.4
Hyrich, K.L.5
-
11
-
-
84855989829
-
Inflammasomes in health and disease
-
10.1038/nature10759 [doi]
-
Strowig T, Henao-Mejia J, Elinav E, Flavell R (2012) Inflammasomes in health and disease. Nature 481: 278-286. 10.1038/nature10759 [doi].
-
(2012)
Nature
, vol.481
, pp. 278-286
-
-
Strowig, T.1
Henao-Mejia, J.2
Elinav, E.3
Flavell, R.4
-
12
-
-
82455162312
-
Negative regulation of NF-kappaB and its involvement in rheumatoid arthritis
-
ar3324 [pii];10.1186/ar3324 [doi]
-
van LG, Beyaert R (2011) Negative regulation of NF-kappaB and its involvement in rheumatoid arthritis. Arthritis Res Ther 13: 221. ar3324 [pii];10.1186/ar3324 [doi].
-
(2011)
Arthritis Res Ther
, vol.13
, pp. 221
-
-
Van, L.G.1
Beyaert, R.2
-
13
-
-
84855163540
-
Intrinsic danger: Activation of Toll-like receptors in rheumatoid arthritis
-
ker257 [pii];10.1093/rheumatology/ker257 [doi]
-
Goh FG, Midwood KS (2012) Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis. Rheumatology (Oxford) 51: 7-23. ker257 [pii];10.1093/rheumatology/ker257 [doi].
-
(2012)
Rheumatology (Oxford)
, vol.51
, pp. 7-23
-
-
Goh, F.G.1
Midwood, K.S.2
-
14
-
-
17644375193
-
Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium
-
ard.2004.025577 [pii];10.1136/ard.2004.025577 [doi]
-
Rosengren S, Hoffman HM, Bugbee W, Boyle DL (2005) Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium. Ann Rheum Dis 64: 708-714. ard.2004.025577 [pii];10.1136/ard.2004.025577 [doi].
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 708-714
-
-
Rosengren, S.1
Hoffman, H.M.2
Bugbee, W.3
Boyle, D.L.4
-
15
-
-
60249090304
-
Rheumatoid arthritis
-
S0140-6736(09)60008-8 [pii];10.1016/S0140-6736(09)60008-8 [doi]
-
Klareskog L, Catrina AI, Paget S (2009) Rheumatoid arthritis. Lancet 373: 659-672. S0140-6736(09)60008-8 [pii];10.1016/S0140-6736(09)60008-8 [doi].
-
(2009)
Lancet
, vol.373
, pp. 659-672
-
-
Klareskog, L.1
Catrina, A.I.2
Paget, S.3
-
16
-
-
79951697490
-
DANBIO-powerful research database and electronic patient record
-
keq309 [pii];10.1093/rheumatology/keq309 [doi]
-
Hetland ML (2011) DANBIO-powerful research database and electronic patient record. Rheumatology (Oxford) 50: 69-77. keq309 [pii];10.1093/ rheumatology/keq309 [doi].
-
(2011)
Rheumatology (Oxford)
, vol.50
, pp. 69-77
-
-
Hetland, M.L.1
-
17
-
-
84927177410
-
Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease
-
tpj201419 [pii];10.1038/tpj.2014.19 [doi]
-
Bank S, Andersen PS, Burisch J, Pedersen N, Roug S, et al. (2014) Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease. Pharmacogenomics J. tpj201419 [pii];10.1038/tpj.2014.19 [doi].
-
(2014)
Pharmacogenomics J
-
-
Bank, S.1
Andersen, P.S.2
Burisch, J.3
Pedersen, N.4
Roug, S.5
-
18
-
-
84903397357
-
Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort
-
Accepted for publication
-
Bank S, Andersen PS, Nexo BA, Sode J, Vogel U, et al. (2014) Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort. PLoS ONE (Accepted for publication).
-
(2014)
PLoS ONE
-
-
Bank, S.1
Andersen, P.S.2
Nexo, B.A.3
Sode, J.4
Vogel, U.5
-
19
-
-
57249114505
-
SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap
-
btn564 [pii];10.1093/bioinformatics/btn564 [doi]
-
Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O'Donnell CJ, et al. (2008) SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 24: 2938-2939. btn564 [pii];10.1093/bioinformatics/ btn564 [doi].
-
(2008)
Bioinformatics
, vol.24
, pp. 2938-2939
-
-
Johnson, A.D.1
Handsaker, R.E.2
Pulit, S.L.3
Nizzari, M.M.4
O'Donnell, C.J.5
-
20
-
-
84878599946
-
High-Quality and -Quantity DNA Extraction from Frozen Archival Blood Clots for Genotyping of Single-Nucleotide Polymorphisms
-
10.1089/gtmb.2012.0429 [doi]
-
Bank S, Nexo BA, Andersen V, Vogel U, Andersen PS (2013) High-Quality and -Quantity DNA Extraction from Frozen Archival Blood Clots for Genotyping of Single-Nucleotide Polymorphisms. Genet Test Mol Biomarkers 17: 501-503. 10.1089/gtmb.2012.0429 [doi].
-
(2013)
Genet Test Mol Biomarkers
, vol.17
, pp. 501-503
-
-
Bank, S.1
Nexo, B.A.2
Andersen, V.3
Vogel, U.4
Andersen, P.S.5
-
22
-
-
12244264435
-
Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits
-
DOI 10.1093/bioinformatics/19.1.149
-
Purcell S, Cherny SS, Sham PC (2003) Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19: 149-150. (Pubitemid 36150192)
-
(2003)
Bioinformatics
, vol.19
, Issue.1
, pp. 149-150
-
-
Purcell, S.1
Cherny, S.S.2
Sham, P.C.3
-
23
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B 57: 289-300.
-
(1995)
J R Stat Soc Series B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
24
-
-
84857743749
-
Common genetic variations in the NALP3 inflammasome are associated with delayed apoptosis of human neutrophils
-
10.1371/journal.pone.0031326 [doi];PONE-D-10-02541 [pii]
-
Blomgran R, Patcha BV, Verma D, Bergstrom I, Soderkvist P, et al. (2012) Common genetic variations in the NALP3 inflammasome are associated with delayed apoptosis of human neutrophils. PLoS One 7: e31326. 10.1371/journal.pone.0031326 [doi];PONE-D-10-02541 [pii].
-
(2012)
PLoS One
, vol.7
-
-
Blomgran, R.1
Patcha, B.V.2
Verma, D.3
Bergstrom, I.4
Soderkvist, P.5
-
25
-
-
70449724715
-
Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma
-
Hitomi Y, Ebisawa M, Tomikawa M, Imai T, Komata T, et al. (2009) Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. J Allergy Clin Immunol 124: 779-785.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 779-785
-
-
Hitomi, Y.1
Ebisawa, M.2
Tomikawa, M.3
Imai, T.4
Komata, T.5
-
26
-
-
61449083796
-
Tobacco smoke: Involvement of reactive oxygen species and stable free radicals in mechanisms of oxidative damage, carcinogenesis and synergistic effects with other respirable particles
-
10.3390/ijerph6020445 [doi]
-
Valavanidis A, Vlachogianni T, Fiotakis K (2009) Tobacco smoke: involvement of reactive oxygen species and stable free radicals in mechanisms of oxidative damage, carcinogenesis and synergistic effects with other respirable particles. Int J Environ Res Public Health 6: 445-462. 10.3390/ijerph6020445 [doi].
-
(2009)
Int J Environ Res Public Health
, vol.6
, pp. 445-462
-
-
Valavanidis, A.1
Vlachogianni, T.2
Fiotakis, K.3
-
27
-
-
84893822649
-
S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-kB
-
doi:10.1371/journal.pone.0072138
-
Simard JC, Cesaro A, Chapeton-Montes J, Tardif M, Antoine F, et al. (2013) S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-kB. PLoS ONE 8: e72138. doi:10.1371/journal.pone.0072138.
-
(2013)
PLoS ONE
, vol.8
-
-
Simard, J.C.1
Cesaro, A.2
Chapeton-Montes, J.3
Tardif, M.4
Antoine, F.5
-
28
-
-
0032542897
-
What's wrong with Bonferroni adjustments
-
Perneger TV (1998) What's wrong with Bonferroni adjustments. BMJ 316: 1236-1238.
-
(1998)
BMJ
, vol.316
, pp. 1236-1238
-
-
Perneger, T.V.1
-
29
-
-
80053526818
-
Recommendations for publication of genetic association studies in Arthritis & Rheumatism
-
Plenge RM, Bridges SL, Huizinga TWJ, Criswell LA, Gregersen PK (2011) Recommendations for publication of genetic association studies in Arthritis & Rheumatism. Arthritis & Rheumatism 63: 2839-2847.
-
(2011)
Arthritis & Rheumatism
, vol.63
, pp. 2839-2847
-
-
Plenge, R.M.1
Bridges, S.L.2
Huizinga, T.W.J.3
Criswell, L.A.4
Gregersen, P.K.5
-
30
-
-
46849110633
-
Do changes in prescription practice in patients with rheumatoid arthritis treated with biological agents affect treatment response and adherence to therapy? Results from the nationwide Danish DANBIO Registry
-
ard.2007.087262 [pii];10.1136/ard.2007.087262 [doi]
-
Hetland ML, Lindegaard HM, Hansen A, Podenphant J, Unkerskov J, et al. (2008) Do changes in prescription practice in patients with rheumatoid arthritis treated with biological agents affect treatment response and adherence to therapy? Results from the nationwide Danish DANBIO Registry. Ann Rheum Dis 67: 1023-1026. ard.2007.087262 [pii];10.1136/ard.2007.087262 [doi].
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1023-1026
-
-
Hetland, M.L.1
Lindegaard, H.M.2
Hansen, A.3
Podenphant, J.4
Unkerskov, J.5
-
31
-
-
78650748817
-
Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome
-
10.1371/journal.pone.0014326 [doi]
-
Coenen MJ, Enevold C, Barrera P, Schijvenaars MM, Toonen EJ, et al. (2010) Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome. PLoS One 5: e14326. 10.1371/journal.pone.0014326 [doi].
-
(2010)
PLoS One
, vol.5
-
-
Coenen, M.J.1
Enevold, C.2
Barrera, P.3
Schijvenaars, M.M.4
Toonen, E.J.5
-
32
-
-
79954626120
-
A regulatory polymorphism in promoter region of TNFR1 gene is associated with Kawasaki disease in Chinese individuals
-
S0198-8859(11)00032-2 [pii];10.1016/j.humimm.2011.02.004 [doi]
-
Wang GB, Li CR, Yang J, Wen PQ, Jia SL (2011) A regulatory polymorphism in promoter region of TNFR1 gene is associated with Kawasaki disease in Chinese individuals. Hum Immunol 72: 451-457. S0198-8859(11)00032-2 [pii];10.1016/j. humimm.2011.02.004 [doi].
-
(2011)
Hum Immunol
, vol.72
, pp. 451-457
-
-
Wang, G.B.1
Li, C.R.2
Yang, J.3
Wen, P.Q.4
Jia, S.L.5
-
33
-
-
80054788315
-
A genetic variant in the IL-17 promoter is functionally associated with acute graft-versus-host disease after unrelated bone marrow transplantation
-
10.1371/journal.pone.0026229 [doi];PONE-D-11-15752 [pii]
-
Espinoza JL, Takami A, Nakata K, Onizuka M, Kawase T, et al. (2011) A genetic variant in the IL-17 promoter is functionally associated with acute graft-versus-host disease after unrelated bone marrow transplantation. PLoS One 6: e26229. 10.1371/journal.pone.0026229 [doi];PONE-D-11-15752 [pii].
-
(2011)
PLoS One
, vol.6
-
-
Espinoza, J.L.1
Takami, A.2
Nakata, K.3
Onizuka, M.4
Kawase, T.5
-
34
-
-
32144455365
-
Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context
-
ddi469 [pii];10.1093/hmg/ddi469 [doi]
-
Chen H, Wilkins LM, Aziz N, Cannings C, Wyllie DH, et al. (2006) Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context. Hum Mol Genet 15: 519-529. ddi469 [pii];10.1093/hmg/ddi469 [doi].
-
(2006)
Hum Mol Genet
, vol.15
, pp. 519-529
-
-
Chen, H.1
Wilkins, L.M.2
Aziz, N.3
Cannings, C.4
Wyllie, D.H.5
-
35
-
-
34347342837
-
Functional significance of gene polymorphisms in the promoter of myeloid differentiation-2
-
10.1097/01.sla.0000262788.67171.3f [doi];00000658-200707000-00023 [pii]
-
Gu W, Shan YA, Zhou J, Jiang DP, Zhang L, et al. (2007) Functional significance of gene polymorphisms in the promoter of myeloid differentiation-2. Ann Surg 246: 151-158. 10.1097/01.sla.0000262788.67171.3f [doi];00000658- 200707000-00023 [pii].
-
(2007)
Ann Surg
, vol.246
, pp. 151-158
-
-
Gu, W.1
Shan, Y.A.2
Zhou, J.3
Jiang, D.P.4
Zhang, L.5
-
36
-
-
0033787711
-
A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: Absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production
-
10.1016/S0198-8859(00)00167-1 [doi]
-
Pravica V, Perrey C, Stevens A, Lee JH, Hutchinson IV (2000) A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: Absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production. Human Immunology 61: 863-866. 10.1016/S0198-8859(00)00167- 1 [doi].
-
(2000)
Human Immunology
, vol.61
, pp. 863-866
-
-
Pravica, V.1
Perrey, C.2
Stevens, A.3
Lee, J.H.4
Hutchinson, I.V.5
|