Optimizing Metabolite Production Using Periodic Oscillations

PLoS Computational Biology

Volumn 10, Issue 6, 2014, Pages

  Sowa, Steven W ^a   Baldea, Michael ^b   Contreras, Lydia M ^b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b The University of Texas at Austin   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; ENZYMES; ESCHERICHIA COLI; METABOLISM; PHYSIOLOGY;

CENTRAL CARBON METABOLISMS; DYNAMIC OPTIMIZATION; KINETIC MODELS; METABOLITE PRODUCTION; MICROBIAL STRAIN; OVEREXPRESSIONS; PATHWAY GENES; PERIODIC OSCILLATION; PHOSPHOENOLPYRUVATES; TIME OSCILLATION;

METABOLITES;

CARBON; FRUCTOSE BISPHOSPHATASE; PHOSPHOENOLPYRUVATE; PYRUVATE SYNTHASE; PYRUVATE WATER DIKINASE; UNCLASSIFIED DRUG; ENZYME;

AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; AMPLITUDE MODULATION; ARTICLE; CARBON METABOLISM; CONTROLLED STUDY; ESCHERICHIA COLI; FEASIBILITY STUDY; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; NONHUMAN; OSCILLATION; OUTCOME ASSESSMENT; PHASE TRANSITION; PREDICTION; PROCESS OPTIMIZATION; SENSITIVITY ANALYSIS; VALIDATION PROCESS; BIOLOGICAL MODEL; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; PROCEDURES; SYSTEMS BIOLOGY;

ENZYMES; ESCHERICHIA COLI; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; PHOSPHOENOLPYRUVATE; SYSTEMS BIOLOGY;

EID: 84903388935     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003658     Document Type: Article

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