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Volumn 31, Issue 3, 2014, Pages 185-192

Impact of anticholinergic discontinuation on cognitive outcomes in older people: A systematic review

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT;

EID: 84903363295     PISSN: 1170229X     EISSN: 11791969     Source Type: Journal    
DOI: 10.1007/s40266-014-0158-4     Document Type: Review
Times cited : (40)

References (47)
  • 1
    • 48449102484 scopus 로고    scopus 로고
    • Anticholinergic activity of 107 medications commonly used by older adults
    • Chew ML, Mulsant BH, Pollock BG, et al. Anticholinergic activity of 107 medications commonly used by older adults. J Am Geriatr Soc. 2008;56:1333-41.
    • (2008) J Am Geriatr Soc , vol.56 , pp. 1333-1341
    • Chew, M.L.1    Mulsant, B.H.2    Pollock, B.G.3
  • 2
    • 0036252287 scopus 로고    scopus 로고
    • Use of anticholinergic medications by older adults with dementia
    • DOI 10.1046/j.1532-5415.2002.50208.x
    • Roe CM, Anderson MJ, Spivack B. Use of anticholinergic medications by older adults with dementia. J Am Geriatr Soc. 2002;50:836-42. (Pubitemid 34496679)
    • (2002) Journal of the American Geriatrics Society , vol.50 , Issue.5 , pp. 836-842
    • Roe, C.M.1    Anderson, M.J.2    Spivack, B.3
  • 4
    • 0037315114 scopus 로고    scopus 로고
    • Serum anticholinergic activity in a community-based sample of older adults: Relationship with cognitive performance
    • DOI 10.1001/archpsyc.60.2.198
    • Mulsant BH, Pollock BG, Kirshner M, et al. Serum anticholinergic activity in a community-based sample of older adults: relationship with cognitive performance. Arch Gen Psychiatry. 2003;60:198-203. (Pubitemid 36173127)
    • (2003) Archives of General Psychiatry , vol.60 , Issue.2 , pp. 198-203
    • Mulsant, B.H.1    Pollock, B.G.2    Kirshner, M.3    Shen, C.4    Dodge, H.5    Ganguli, M.6
  • 5
    • 78649361540 scopus 로고    scopus 로고
    • Prevalence and predictors of anticholinergic medication use in elderly nursing home residents with dementia
    • Chatterjee S, Mehta S, Sherer J, et al. Prevalence and predictors of anticholinergic medication use in elderly nursing home residents with dementia. Drugs Aging. 2010;27:987-97.
    • (2010) Drugs Aging , vol.27 , pp. 987-997
    • Chatterjee, S.1    Mehta, S.2    Sherer, J.3
  • 6
    • 0026668120 scopus 로고
    • Anticholinergic effects of drugs commonly prescribed for the elderly: Potential means for assessing risk of delirium
    • Tune L, Carr S, Hoag E, et al. Anticholinergic effects of drugs commonly prescribed for the elderly: potential means for assessing risk of delirium. Am J Psychiatry. 1992;149:1393-4.
    • (1992) Am J Psychiatry , vol.149 , pp. 1393-1394
    • Tune, L.1    Carr, S.2    Hoag, E.3
  • 7
    • 16644402640 scopus 로고    scopus 로고
    • The concurrent use of anticholinergics and cholinesterase inhibitors: Rare event or common practice?
    • DOI 10.1111/j.1532-5415.2004.52563.x
    • Carnahan RM, Lund BC, Perry PJ, et al. The concurrent use of anticholinergics and cholinesterase inhibitors: rare event or common practice? J Am Geriatr Soc. 2004;52:2082-7. (Pubitemid 41725028)
    • (2004) Journal of the American Geriatrics Society , vol.52 , Issue.12 , pp. 2082-2087
    • Carnahan, R.M.1    Lund, B.C.2    Perry, P.J.3    Chrischilles, E.A.4
  • 8
    • 84886498695 scopus 로고    scopus 로고
    • Anticholinergic component of the Drug Burden Index and the Anticholinergic Drug Scale as measures of anticholinergic exposure in older people in New Zealand: A population-level study
    • Narayan SW, Hilmer SN, Horsburgh S, et al. Anticholinergic component of the Drug Burden Index and the Anticholinergic Drug Scale as measures of anticholinergic exposure in older people in New Zealand: a population-level study. Drugs Aging. 2013;30:927-34.
    • (2013) Drugs Aging , vol.30 , pp. 927-934
    • Narayan, S.W.1    Hilmer, S.N.2    Horsburgh, S.3
  • 9
    • 0024440577 scopus 로고
    • Snipping the thread of life. Antimuscarinic side effects of medications in the elderly
    • DOI 10.1001/archinte.149.11.2414
    • Peters NL. Snipping the thread of life: antimuscarinic side effects of medications in the elderly. Arch Intern Med. 1989;149:2414-20. (Pubitemid 19283196)
    • (1989) Archives of Internal Medicine , vol.149 , Issue.11 , pp. 2414-2420
    • Peters, N.L.1
  • 10
    • 0034795320 scopus 로고    scopus 로고
    • Anticholinergic effects of medication in elderly patients
    • Tune LE. Anticholinergic effects of medication in elderly patients. J Clin Psychiatry. 2001;62(Suppl 21):11-4. (Pubitemid 32937572)
    • (2001) Journal of Clinical Psychiatry , vol.62 , Issue.SUPPL. 22 , pp. 11-14
    • Tune, L.E.1
  • 11
    • 0027636902 scopus 로고
    • The problems of anticholinergic adverse effects in older patients
    • Feinberg M. The problems of anticholinergic adverse effects in older patients. Drugs Aging. 1993;3:335-48.
    • (1993) Drugs Aging , vol.3 , pp. 335-348
    • Feinberg, M.1
  • 12
    • 79961065476 scopus 로고    scopus 로고
    • Paying attention to pharmacokinetic and pharmacodynamic mechanisms to progress in the area of anticholinergic use in geriatric patients
    • de Leon J. Paying attention to pharmacokinetic and pharmacodynamic mechanisms to progress in the area of anticholinergic use in geriatric patients. Curr Drug Metab. 2011;12:635-46.
    • (2011) Curr Drug Metab , vol.12 , pp. 635-646
    • De Leon, J.1
  • 13
    • 79961084008 scopus 로고    scopus 로고
    • Age-related changes in pharmacokinetics
    • Shi S, Klotz U. Age-related changes in pharmacokinetics. Curr Drug Metab. 2011;12:601-10.
    • (2011) Curr Drug Metab , vol.12 , pp. 601-610
    • Shi, S.1    Klotz, U.2
  • 14
    • 0029904315 scopus 로고    scopus 로고
    • A pharmacoepidemiological evaluation of anticholinergic prescribing patterns in the elderly
    • DOI 10.1002/(SICI)1099-1557(199605)5:3<155::AID-PD
    • Remillard AJ. A pharmacoepidemiological evaluation of anticholinergic prescribing patterns in the elderly. Pharmacoepidemiol Drug Saf. 1996;5:155-64. (Pubitemid 26227816)
    • (1996) Pharmacoepidemiology and Drug Safety , vol.5 , Issue.3 , pp. 155-164
    • Remillard, A.J.1
  • 16
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: Ageing and microvascular disease-systematic review and meta-analysis
    • Farrall AJ, Wardlaw JM. Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis. Neurobiol Aging. 2009;30:337-52.
    • (2009) Neurobiol Aging , vol.30 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 17
    • 67349220310 scopus 로고    scopus 로고
    • Blood-brain barrier alterations in ageing and dementia
    • Popescu BO, Toescu EC, Popescu LM, et al. Blood-brain barrier alterations in ageing and dementia. J Neurol Sci. 2009;283:99-106.
    • (2009) J Neurol Sci , vol.283 , pp. 99-106
    • Popescu, B.O.1    Toescu, E.C.2    Popescu, L.M.3
  • 18
    • 77954890671 scopus 로고    scopus 로고
    • Association between prescribing of antimuscarinic drugs and antimuscarinic adverse effects in older people
    • Bostock CV, Soiza RL, Mangoni AA. Association between prescribing of antimuscarinic drugs and antimuscarinic adverse effects in older people. Expert Rev Clin Pharmacol. 2010;3:441-52.
    • (2010) Expert Rev Clin Pharmacol , vol.3 , pp. 441-452
    • Bostock, C.V.1    Soiza, R.L.2    Mangoni, A.A.3
  • 24
    • 79960941923 scopus 로고    scopus 로고
    • Anticholinergic medication use and cognitive impairment in the older population: The Medical Research Council Cognitive Function and Ageing Study
    • Fox C, Richardson K, Maidment ID, et al. Anticholinergic medication use and cognitive impairment in the older population: the Medical Research Council Cognitive Function and Ageing Study. J Am Geriatr Soc. 2011;59:1477-83.
    • (2011) J Am Geriatr Soc , vol.59 , pp. 1477-1483
    • Fox, C.1    Richardson, K.2    Maidment, I.D.3
  • 26
    • 41949083073 scopus 로고    scopus 로고
    • The anticholinergic risk scale and anticholinergic adverse effects in older persons
    • DOI 10.1001/archinternmed.2007.106
    • Rudolph JL, Salow MJ, Angelini MC, et al. The Anticholinergic Risk Scale and anticholinergic adverse effects in older persons. Arch Intern Med. 2008;168:508-13. (Pubitemid 351547214)
    • (2008) Archives of Internal Medicine , vol.168 , Issue.5 , pp. 508-513
    • Rudolph, J.L.1    Salow, M.J.2    Angelini, M.C.3    McGlinchey, R.E.4
  • 27
    • 80052006496 scopus 로고    scopus 로고
    • Drugs with anticholinergic properties: A current perspective on use and safety
    • Gerretsen P, Pollock BG. Drugs with anticholinergic properties: a current perspective on use and safety. Expert Opin Drug Saf. 2011;10:751-65.
    • (2011) Expert Opin Drug Saf , vol.10 , pp. 751-765
    • Gerretsen, P.1    Pollock, B.G.2
  • 28
    • 53749091555 scopus 로고    scopus 로고
    • Serum anticholinergic activity and cerebral cholinergic dysfunction: An EEG study in frail elderly with and without delirium
    • Thomas C, Hestermann U, Kopitz J, et al. Serum anticholinergic activity and cerebral cholinergic dysfunction: an EEG study in frail elderly with and without delirium. BMC Neurosci. 2008;9:86.
    • (2008) BMC Neurosci , vol.9 , pp. 86
    • Thomas, C.1    Hestermann, U.2    Kopitz, J.3
  • 29
    • 70349490787 scopus 로고    scopus 로고
    • Anticholinergic activity of commonly prescribed medications and neuropsychiatric adverse events in older people
    • Nishtala PS, Fois RA, McLachlan AJ, et al. Anticholinergic activity of commonly prescribed medications and neuropsychiatric adverse events in older people. J Clin Pharmacol. 2009;49:1176-84.
    • (2009) J Clin Pharmacol , vol.49 , pp. 1176-1184
    • Nishtala, P.S.1    Fois, R.A.2    McLachlan, A.J.3
  • 30
    • 33645128411 scopus 로고    scopus 로고
    • Comorbidity profile of dementia patients in primary care: Are they sicker?
    • Schubert CC, Boustani M, Callahan CM, et al. Comorbidity profile of dementia patients in primary care: are they sicker? J Am Geriatr Soc. 2006;54:104-9.
    • (2006) J Am Geriatr Soc , vol.54 , pp. 104-109
    • Schubert, C.C.1    Boustani, M.2    Callahan, C.M.3
  • 31
    • 84884658777 scopus 로고    scopus 로고
    • Measures of anticholinergic drug exposure, serum anticholinergic activity, and all-cause postdischarge mortality in older hospitalized patients with hip fractures
    • Mangoni AA, van Munster BC, Woodman RJ, et al. Measures of anticholinergic drug exposure, serum anticholinergic activity, and all-cause postdischarge mortality in older hospitalized patients with hip fractures. Am J Geriatr Psychiatry. 2013;21:785-93.
    • (2013) Am J Geriatr Psychiatry , vol.21 , pp. 785-793
    • Mangoni, A.A.1    Van Munster, B.C.2    Woodman, R.J.3
  • 32
    • 79955982494 scopus 로고    scopus 로고
    • Associations between Drug Burden Index and falls in older people in residential aged care
    • Wilson NM, Hilmer SN, March LM, et al. Associations between Drug Burden Index and falls in older people in residential aged care. J Am Geriatr Soc. 2011;59:875-80.
    • (2011) J Am Geriatr Soc , vol.59 , pp. 875-880
    • Wilson, N.M.1    Hilmer, S.N.2    March, L.M.3
  • 33
    • 79551714673 scopus 로고    scopus 로고
    • Anticholinergic drug use and mortality among residents of long-term care facilities: A prospective cohort study
    • Kumpula EK, Bell JS, Soini H, et al. Anticholinergic drug use and mortality among residents of long-term care facilities: a prospective cohort study. J Clin Pharmacol. 2011;51:256-63.
    • (2011) J Clin Pharmacol , vol.51 , pp. 256-263
    • Kumpula, E.K.1    Bell, J.S.2    Soini, H.3
  • 34
    • 70350492552 scopus 로고    scopus 로고
    • Effects of potent anticholinergics, sedatives and antipsychotics on postoperative mortality in elderly patients with hip fracture: A retrospective, population-based study
    • Panula J, Puustinen J, Jaatinen P, et al. Effects of potent anticholinergics, sedatives and antipsychotics on postoperative mortality in elderly patients with hip fracture: a retrospective, population-based study. Drugs Aging. 2009;26:963-71.
    • (2009) Drugs Aging , vol.26 , pp. 963-971
    • Panula, J.1    Puustinen, J.2    Jaatinen, P.3
  • 36
    • 75649139099 scopus 로고    scopus 로고
    • Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia
    • Tomida K, Takahashi N, Saito S, et al. Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia. Psychiatry Clin Neurosci. 2010;64:62-9.
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 62-69
    • Tomida, K.1    Takahashi, N.2    Saito, S.3
  • 37
    • 0036174202 scopus 로고    scopus 로고
    • Effects of anticholinergic drug withdrawal on memory, regional cerebral blood flow and extra-pyramidal side effects in schizophrenic patients
    • DOI 10.1055/s-2002-19831
    • Mori K, Yamashita H, Nagao M, et al. Effects of anticholinergic drug withdrawal on memory, regional cerebral blood flow and extrapyramidal side effects in schizophrenic patients. Pharmacopsychiatry. 2002;35:6-11. (Pubitemid 34135452)
    • (2002) Pharmacopsychiatry , vol.35 , Issue.1 , pp. 6-11
    • Mori, K.1    Yamashita, H.2    Nagao, M.3    Horiguchi, J.4    Yamawaki, S.5
  • 38
    • 78650929603 scopus 로고    scopus 로고
    • Effects of discontinuation of long-term biperiden use on cognitive function and quality of life in schizophrenia
    • Ogino S, Miyamoto S, Tenjin T, et al. Effects of discontinuation of long-term biperiden use on cognitive function and quality of life in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35:78-83.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 78-83
    • Ogino, S.1    Miyamoto, S.2    Tenjin, T.3
  • 39
    • 0021086959 scopus 로고
    • The withdrawal of benztropine mesylate in chronic schizophrenic patients
    • Baker LA, Cheng LY, Amara IB. The withdrawal of benztropine mesylate in chronic schizophrenic patients. Br J Psychiatry. 1983;143:584-90. (Pubitemid 14235597)
    • (1983) British Journal of Psychiatry , vol.143 , Issue.6 , pp. 584-590
    • Baker, L.A.1    Cheng, L.Y.2    Amara, I.B.3
  • 40
    • 84864501165 scopus 로고    scopus 로고
    • Preventive Services Task Force Procedure Manual
    • U.S. Accessed 20 Dec 2013
    • U.S. Preventive Services Task Force Procedure Manual. AHRQ Publication No. 08-05118-EF; 2008. http://www.uspreventiveservicestaskforce.org/uspstf08/ methods/procmanual.htm. Accessed 20 Dec 2013.
    • (2008) AHRQ Publication No. 08-05118-EF
  • 41
    • 0025878943 scopus 로고
    • The relationship of serum anticholinergic activity to mental status performance in an elderly nursing home population
    • Tollefson GD, Montague-Clouse J, Lancaster SP. The relationship of serum anticholinergic activity to mental status performance in an elderly nursing home population. J Neuropsychiatry Clin Neurosci. 1991;3:314-9.
    • (1991) J Neuropsychiatry Clin Neurosci , vol.3 , pp. 314-319
    • Tollefson, G.D.1    Montague-Clouse, J.2    Lancaster, S.P.3
  • 42
    • 1642452857 scopus 로고    scopus 로고
    • Effects of discontinuation of long-term anticholinergic treatment in elderly schizophrenia patients
    • DOI 10.1097/00004850-200401000-00005
    • Drimer T, Shahal B, Barak Y. Effects of discontinuation of long-term anticholinergic treatment in elderly schizophrenia patients. Int Clin Psychopharmacol. 2004;19:27-9. (Pubitemid 38114621)
    • (2004) International Clinical Psychopharmacology , vol.19 , Issue.1 , pp. 27-29
    • Drimer, T.1    Shahal, B.2    Barak, Y.3
  • 43
    • 84873628373 scopus 로고    scopus 로고
    • Cognitive effects of reducing anticholinergic drug burden in a frail elderly population: A randomized controlled trial
    • Kersten H, Molden E, Tolo IK, et al. Cognitive effects of reducing anticholinergic drug burden in a frail elderly population: a randomized controlled trial. J Gerontol A Biol Sci Med Sci. 2013;68:271-8.
    • (2013) J Gerontol a Biol Sci Med Sci , vol.68 , pp. 271-278
    • Kersten, H.1    Molden, E.2    Tolo, I.K.3
  • 45
    • 67749103704 scopus 로고    scopus 로고
    • Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: The 3-City Study
    • Carriere I, Fourrier-Reglat A, Dartigues JF, et al. Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-City Study. Arch Intern Med. 2009;169:1317-24.
    • (2009) Arch Intern Med , vol.169 , pp. 1317-1324
    • Carriere, I.1    Fourrier-Reglat, A.2    Dartigues, J.F.3
  • 46
    • 57149143738 scopus 로고    scopus 로고
    • Cumulative anticholinergic exposure is associated with poor memory and executive function in older men
    • Han L, Agostini JV, Allore HG. Cumulative anticholinergic exposure is associated with poor memory and executive function in older men. J Am Geriatr Soc. 2008;56:2203-10.
    • (2008) J Am Geriatr Soc , vol.56 , pp. 2203-2210
    • Han, L.1    Agostini, J.V.2    Allore, H.G.3
  • 47
    • 84882449192 scopus 로고    scopus 로고
    • Long-term anticholinergic use and the aging brain
    • Cai X, Campbell N, Khan B, et al. Long-term anticholinergic use and the aging brain. Alzheimers Dement. 2013;9:377-85.
    • (2013) Alzheimers Dement , vol.9 , pp. 377-385
    • Cai, X.1    Campbell, N.2    Khan, B.3


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