Trends in potentially inappropriate prescribing amongst older UK primary care patients

Pharmacoepidemiology and Drug Safety

Volumn 16, Issue 6, 2007, Pages 658-667

  De Wilde, Stephen ^a   Carey, Ian M ^a   Harris, Tess ^a   Richards, Nicky ^b   Victor, Christina ^c   Hilton, Sean R ^a   Cook, Derek G ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b CompuFile Ltd ^*  (United Kingdom)

^c UNIVERSITY OF READING   (United Kingdom)

Author keywords

Benzodiazepines; Co proxamol; Elderly; Pharmaco vigilance; Primary care

Indexed keywords

ALPRAZOLAM; AMIODARONE; AMITRIPTYLINE; AMPHETAMINE; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; BISACODYL; CASCARA; CHLORPHENIRAMINE; CIMETIDINE; CLOBAZAM; CLONIDINE; CYCLANDELATE; DEXTROPROPOXYPHENE PLUS PARACETAMOL; DIAZEPAM; DICYCLOVERINE; DIGOXIN; DIPYRIDAMOLE; DOXAZOSIN; ETACRYNIC ACID; FERROUS SULFATE; FLUOXETINE; ISOXSUPRINE; NITRAZEPAM; NONSTEROID ANTIINFLAMMATORY AGENT; RESERPINE; TEMAZEPAM; THIORIDAZINE; UNINDEXED DRUG; ZOLPIDEM;

AGED; ARTICLE; CONTROLLED STUDY; DRUG MEGADOSE; DRUG SURVEILLANCE PROGRAM; GENERAL PRACTICE; GERIATRIC CARE; HIGH RISK PATIENT; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MEDICAL RECORD; PHARMACEUTICAL CARE; PRESCRIPTION; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; RISK REDUCTION; UNITED KINGDOM;

AGED; DRUG UTILIZATION; GREAT BRITAIN; HUMANS; PRIMARY HEALTH CARE; TIME FACTORS;

EID: 34447261210     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.1306     Document Type: Article

References (19)

1. Hanlon JT, Schmader KE, Koronkowski MJ, et al. Adverse drug events in high risk older outpatients. J Am Geriatr Soc 1997; 45(8): 945-948.
2. Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. Arch Intern Med 1997; 157(14): 1531-1536.
3. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003; 163(22): 2716-2724.
4. McLeod PJ, Huang AR, Tamblyn RM, Gayton DC. Defining inappropriate practices in prescribing for elderly people: a national consensus panel. CMAJ 1997; 156(3): 385-391.
5. Zhan C, Sangl J, Bierman AS, et al. Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey. JAMA 2001; 286(22): 2823-2829.
6. Fialova D, Topinkova E, Gambassi G, et al. Potentially inappropriate medication use among elderly home care patients in Europe. JAMA 2005; 293(11): 1348-1358.
7. van der Hooft CS, Jong GW, Dieleman JP et al. Inappropriate drug prescribing in older adults: the updated 2002 Beers criteria-a population-based cohort study. Br J Clin Pharmacol 2005; 60(2): 137-144.
8. Gosney M, Vellodi C, Tallis R, Edmond E, M-Hamouz S. Inappropriate prescribing in Part III residential homes. Health Trends 1989; 21: 129-131.
9. Carey IM, Cook DG, DeWilde S, et al. Developing a large electronic primary care database (Doctors' Independent Network) for research. Int J Med Inf 2004; 73(5): 443-453.
10. Carey IM, Cook DG, De Wilde S, et al. Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD). BMC Fam Pract 2003; 4(1): 14.
11. DeWilde S, Carey I, Bremner SA, et al. A comparison of the recording of 30 common childhood conditions in the Doctors' Independent Network and General Practice Research Databases. Health Stat Q 2004; 22 21-31.
12. Bryson HM, Wilde MI. Amitriptyline. A review of its pharmacological properties and therapeutic use in chronic pain states. Drugs Aging 1996; 8(6): 459-476.
13. Withdrawal of co-proxamol products and interim updated prescribing information. 2005. http://www.mhra.gov.uk/home/groups/pl-a/documents/ drugsafetymessage/con019461.pdf. Last Accessed:22-5-2006.
14. Thioridazine: Restricted indications and new warnings on cardiotoxicity. 2000. http://www.info.doh.gov.uk/doh/embroadcast. nsf/0/ fc5d1f63a16da86b80256dad00480816/SFILE/cemcmo200018.pdf. Last Accessed:22-5-2006.
15. Neutel CI, Hirdes JP, Maxwell CJ, Patton SB. New evidence on benzodiazepine use and falls: the time factor. Age Ageing 1996; 25(4): 273-278.
16. Panneman MJ, Goettsch WG, Kramarz P, Herings RM. The costs of benzodiazepine-associated hospital-treated fall Injuries in the EU: a Pharmo study. Drugs Aging 2003; 20(11): 833-839.
17. Ensrud KE, Blackwell T, Mangione CM, et al. Central nervous system active medications and risk for fractures in older women. Arch Intern Med 2003; 163(8): 949-957.
18. Roberts MS, Stokes JA. Explicit evidence-based prescribing criteria-an important stop in achieving quality therapeutics in nursing homes. Age Ageing 2003; 32(1): 6-7.
19. Oborne CA, Hooper R, Swift CG, Jackson SH. Explicit, evidence-based criteria to assess the quality of prescribing to elderly nursing home residents. Age Ageing 2003; 32(1): 102-108.