Neuroprotective effects of total steroid saponins on cerebral ischemia injuries in an animal model of focal ischemia/reperfusion

Planta Medica

Volumn 80, Issue 8-9, 2014, Pages 637-644

  Zhang, Xinxin ^a   Chen, Lin ^a   Dang, Xuan ^a   Liu, Jianli ^a   Ito, Yoichiro ^b   Sun, Wenji ^a  

^a NORTHWEST UNIVERSITY   (China)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

anti edema; anti oxidative; Dioscorea zingiberensis; Dioscoreaceae; ischemia reperfusion; middle cerebral artery occlusion; steroid saponins

Indexed keywords

AQUAPORIN 4; CATALASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NIMODIPINE; NITRIC OXIDE; SAPONIN DERIVATIVE; STEROID SAPONIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT; PLANT EXTRACT; SAPONIN; STEROID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN WATER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIOSCOREA ZINGIBERENSIS; HIPPOCAMPAL CA1 REGION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGICAL DEFICIT SCORE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SCORING SYSTEM; WESTERN BLOTTING; YAM; ANIMAL; BRAIN; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; EDEMA; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN; DIOSCOREA; DISEASE MODELS, ANIMAL; EDEMA; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SAPONINS; STEROIDS;

EID: 84903307164     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1368584     Document Type: Article

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