Towards non-invasive imaging of vulnerable atherosclerotic plaques by targeting co-stimulatory molecules

International Journal of Cardiology

Volumn 174, Issue 3, 2014, Pages 503-515

  Müller, Adrienne ^a   Mu, Linjing ^a   Meletta, Romana ^a   Beck, Katharina ^a   Rancic, Zoran ^b   Drandarov, Konstantin ^a   Kaufmann, Philipp A ^b   Ametamey, Simon M ^a   Schibli, Roger ^a   Borel, Nicole ^c   Krämer, Stefanie D ^a  

^a ETH Zurich   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Atherosclerosis; Co stimulatory molecules; Immune system; Positron emission tomography; Vulnerable plaque

Indexed keywords

B7 ANTIGEN; CARBON CD80 ANTIGEN INHIBITOR C 11; CD83 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; MESSENGER RNA; TOLL LIKE RECEPTOR 1; TRACER; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BIOACCUMULATION; CARDIAC IMAGING; CAROTID ATHEROSCLEROSIS; CD28 GENE; CD80 GENE; CD86 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; CTLA4 GENE; FEMALE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; MALE; MOLECULAR STABILITY; MOUSE; NON INVASIVE MEASUREMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMA CLEARANCE; PLASMA CONCENTRATION-TIME CURVE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RADIOISOTOPE DISTRIBUTION; ANIMAL; C57BL MOUSE; CAROTID ENDARTERECTOMY; DIAGNOSTIC USE; NUDE MOUSE; PLAQUE, ATHEROSCLEROTIC; RADIOGRAPHY; SCINTISCANNING; SINGLE BLIND PROCEDURE; TRENDS;

AGED; ANIMALS; ANTIGENS, CD80; ANTIGENS, CD86; AUTORADIOGRAPHY; ENDARTERECTOMY, CAROTID; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, NUDE; PLAQUE, ATHEROSCLEROTIC; POSITRON-EMISSION TOMOGRAPHY; SINGLE-BLIND METHOD;

EID: 84903305166     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.04.071     Document Type: Article

References (35)

1. G.K. Hansson, and P. Libby The immune response in atherosclerosis: a double-edged sword Nat Rev Immunol 6 2006 508 519
2. B.W. Wong, A. Meredith, D. Lin, and B.M. McManus The biological role of inflammation in atherosclerosis Can J Cardiol 28 2012 631 641
3. Y.V. Bobryshev, and R.S. Lord Ultrastructural recognition of cells with dendritic cell morphology in human aortic intima. Contacting interactions of vascular dendritic cells in athero-resistant and athero-prone areas of the normal aorta Arch Histol Cytol 58 1995 307 322
4. E.A. Van Vre, I. Van Brussel, J.M. Bosmans, C.J. Vrints, and H. Bult Dendritic cells in human atherosclerosis: from circulation to atherosclerotic plaques Mediators Inflamm 2011 2011 941396
5. J. George, A. Afek, and B. Gilburd et al. Induction of early atherosclerosis in LDL-receptor-deficient mice immunized with beta2-glycoprotein I Circulation 98 1998 1108 1115
6. J. George, Y. Shoenfeld, and A. Afek et al. Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65 Arterioscler Thromb Vasc Biol 19 1999 505 510
7. A. Kol, G.K. Sukhova, A.H. Lichtman, and P. Libby Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression Circulation 98 1998 300 307
8. R. Kiessling, A. Gronberg, and J. Ivanyi et al. Role of hsp60 during autoimmune and bacterial inflammation Immunol Rev 121 1991 91 111
9. N. Gerdes, and A. Zirlik Co-stimulatory molecules in and beyond co-stimulation - tipping the balance in atherosclerosis? Thromb Haemost 106 2011 804 813
10. C. Buono, H. Pang, Y. Uchida, P. Libby, A.H. Sharpe, and A.H. Lichtman B7-1/B7-2 costimulation regulates plaque antigen-specific T-cell responses and atherogenesis in low-density lipoprotein receptor-deficient mice Circulation 109 2004 2009 2015
11. J.F. Dopheide, U. Sester, and A. Schlitt et al. Monocyte-derived dendritic cells of patients with coronary artery disease show an increased expression of costimulatory molecules CD40, CD80 and CD86 in vitro Coron Artery Dis 18 2007 523 531
12. O.J. de Boer, F. Hirsch, A.C. van der Wal, C.M. van der Loos, P.K. Das, and A.E. Becker Costimulatory molecules in human atherosclerotic plaques: an indication of antigen specific T lymphocyte activation Atherosclerosis 133 1997 227 234
13. N.A. Jager, N. Teteloshvili, C.J. Zeebregts, J. Westra, and M. Bijl Macrophage folate receptor-beta (FR-beta) expression in auto-immune inflammatory rheumatic diseases: a forthcoming marker for cardiovascular risk? Autoimmun Rev 11 2012 621 626
14. B. Dietel, I. Cicha, C.J. Voskens, E. Verhoeven, S. Achenbach, and C.D. Garlichs Decreased numbers of regulatory T cells are associated with human atherosclerotic lesion vulnerability and inversely correlate with infiltrated mature dendritic cells Atherosclerosis 230 2013 92 99
15. H.J. Medbury, V. James, and J. Ngo et al. Differing association of macrophage subsets with atherosclerotic plaque stability Int Angiol 32 2013 74 84
16. P. Huxley, D.H. Sutton, and P. Debnam et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy Chem Biol 11 2004 1651 1658
17. P.C. Nett, G. Zund, R. Pretre, U. Niederhouser, P.R. Vogt, and M. Turina A 20-year follow-up of internal carotid artery endarterectomy with bifurcation advancement Thorac Cardiovasc Surg 48 2000 279 284
18. M. Pedretti, Z. Rancic, and A. Soltermann et al. Comparative immunohistochemical staining of atherosclerotic plaques using F16, F8 and L19: three clinical-grade fully human antibodies Atherosclerosis 208 2010 382 389
19. - DD C(T) Method Methods 25 2001 402 408
20. C.A. Baumann, L. Mu, and N. Wertli et al. Syntheses and pharmacological characterization of novel thiazole derivatives as potential mGluR5 PET ligands Bioorg Med Chem 18 2010 6044 6054
21. D.M. Wilson, X. Wang, E. Walsh, and R.A. Rourick High throughput log D determination using liquid chromatography-mass spectrometry Comb Chem High Throughput Screen 4 2001 511 519
22. H.C. Stary, A.B. Chandler, and R.E. Dinsmore et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association Circulation 92 1995 1355 1374
23. J.N. Redgrave, P. Gallagher, J.K. Lovett, and P.M. Rothwell Critical cap thickness and rupture in symptomatic carotid plaques: the Oxford plaque study Stroke 39 2008 1722 1729
24. C. Erbel, K. Sato, and F.B. Meyer et al. Functional profile of activated dendritic cells in unstable atherosclerotic plaque Basic Res Cardiol 102 2007 123 132
25. J. Sanz, and Z.A. Fayad Imaging of atherosclerotic cardiovascular disease Nature 451 2008 953 957
26. P.J. Habib, J. Green, and R.C. Butterfield et al. Association of cardiac events with coronary artery disease detected by 64-slice or greater coronary CT angiography: a systematic review and meta-analysis Int J Cardiol 169 2013 112 120
27. G. Turc, C. Oppenheim, and O. Naggara et al. Relationships between recent intraplaque hemorrhage and stroke risk factors in patients with carotid stenosis: the HIRISC study Arterioscler Thromb Vasc Biol 32 2012 492 499
28. D. Staub, A.F. Schinkel, and B. Coll et al. Contrast-enhanced ultrasound imaging of the vasa vasorum: from early atherosclerosis to the identification of unstable plaques JACC Cardiovasc Imaging 3 2010 761 771
29. S.P. de Boer, S. Brugaletta, and H.M. Garcia-Garcia et al. Determinants of high cardiovascular risk in relation to plaque-composition of a non-culprit coronary segment visualized by near-infrared spectroscopy in patients undergoing percutaneous coronary intervention Eur Heart J 35 2014 282 289
30. R. Kubota, K. Kubota, S. Yamada, M. Tada, T. Ido, and N. Tamahashi Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18- fluorodeoxyglucose uptake J Nucl Med 35 1994 104 112
31. J.R. Davies, J.H. Rudd, and T.D. Fryer et al. Identification of culprit lesions after transient ischemic attack by combined 18F fluorodeoxyglucose positron-emission tomography and high-resolution magnetic resonance imaging Stroke 36 2005 2642 2647
32. 18F]-fluorodeoxyglucose positron emission tomography Circulation 105 2002 2708 2711
33. 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients J Am Coll Cardiol 48 2006 1818 1824
34. F. Leuschner, and M. Nahrendorf Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic Circ Res 108 2011 593 606
35. W.A. Ritschel, and G.V. Hammer Prediction of the volume of distribution from in vitro data and use for estimating the absolute extent of absorption Int J Clin Pharmacol Ther Toxicol 18 1980 298 316