Aberrant DNA methylation of the PDGF gene in homocysteine-mediated VSMC proliferation and its underlying mechanism

Molecular Medicine Reports

Volumn 10, Issue 2, 2014, Pages 947-954

  Han, Xue Bo ^a   Zhang, Hui Ping ^a   Cao, Cheng Jian ^a   Wang, Yan Hua ^a   Tian, Jue ^a   Yang, Xiao Ling ^a   Yang, An Ning ^a   Wang, Jie ^a   Jiang, Yi Deng ^a   Xu, Hua ^a  

^a NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Atherosclerosis; Homocysteine; Methionine cycle; Methylation; Platelet derived growth factor; Vascular smooth muscle cell proliferation

Indexed keywords

FOLIC ACID; HOMOCYSTEINE; PLATELET DERIVED GROWTH FACTOR; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; MESSENGER RNA;

ARTICLE; ATHEROSCLEROSIS; CELL ACTIVITY; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONCENTRATION RESPONSE; DEMETHYLATION; DNA METHYLATION; EPIGENETICS; GENE SILENCING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; PROMOTER REGION; PROTEIN EXPRESSION; UPREGULATION; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; G1 PHASE CELL CYCLE CHECKPOINT; GENETICS; METABOLISM; UMBILICAL CORD;

CELL PROLIFERATION; CELLS, CULTURED; DNA METHYLATION; FOLIC ACID; G1 PHASE CELL CYCLE CHECKPOINTS; HOMOCYSTEINE; HUMANS; MUSCLE, SMOOTH, VASCULAR; PLATELET-DERIVED GROWTH FACTOR; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; UMBILICAL CORD;

EID: 84903267217     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2249     Document Type: Article

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