메뉴 건너뛰기




Volumn 10, Issue 7, 2014, Pages 1137-1145

Can bevacizumab prolong survival for glioblastoma patients through multiple lines of therapy?

Author keywords

bevacizumab; clinical trial; glioblastoma; multiple lines; newly diagnosed; Phase IIIb; progression; recurrent; trials in progress; vascular endothelial growth factor; VEGF

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; ETOPOSIDE; FOTEMUSTINE; IRINOTECAN; LOMUSTINE; PLACEBO; TEMOZOLOMIDE; ANGIOGENESIS INHIBITOR; MONOCLONAL ANTIBODY;

EID: 84903194653     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.14.75     Document Type: Article
Times cited : (16)

References (55)
  • 1
    • 84871720057 scopus 로고    scopus 로고
    • Continuation of bevacizumab after frst progression in metastatic colorectal cancer (ML18147): A randomised Phase 3 trial
    • Bennouna J, Sastre J, Arnold D et al. Continuation of bevacizumab after frst progression in metastatic colorectal cancer (ML18147): a randomised Phase 3 trial. Lancet Oncol. 14, 29-37 (2013).
    • (2013) Lancet Oncol. , vol.14 , pp. 29-37
    • Bennouna, J.1    Sastre, J.2    Arnold, D.3
  • 2
    • 4944255253 scopus 로고    scopus 로고
    • Genetic pathways to glioblastoma: A population-based study
    • Ohgaki H, Dessen P, Jourde B et al. Genetic pathways to glioblastoma: a population-based study. Cancer Res. 64, 6892-6899 (2004)
    • (2004) Cancer Res. , vol.64 , pp. 6892-6899
    • Ohgaki, H.1    Dessen, P.2    Jourde, B.3
  • 3
    • 84903219428 scopus 로고    scopus 로고
    • Central Brain Tumor Registry of the United States (CBRTUS)
    • Central Brain Tumor Registry of the United States (CBRTUS). www.cbtrus.org
  • 4
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised Phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised Phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 10, 459-466 (2009).
    • (2009) Lancet Oncol. , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 5
    • 77954331628 scopus 로고    scopus 로고
    • High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Stupp R, Tonn JC, Brada M et al. High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 21(Suppl. 5), v190-v193 (2010).
    • (2010) Ann. Oncol. , vol.21 , Issue.SUPPL. 5
    • Stupp, R.1    Tonn, J.C.2    Brada, M.3
  • 6
    • 75649092598 scopus 로고    scopus 로고
    • Bevacizumab in brain tumors: Ready for primetime?
    • Franceschi E, Tosoni A, Girardi F et al. Bevacizumab in brain tumors: ready for primetime? Future Oncol. 5, 1183-1184 (2009).
    • (2009) Future Oncol. , vol.5 , pp. 1183-1184
    • Franceschi, E.1    Tosoni, A.2    Girardi, F.3
  • 7
    • 84903156992 scopus 로고    scopus 로고
    • NCCN Guidelines Central Nervous System Cancers. Version 1.2012
    • NCCN Guidelines Central Nervous System Cancers. Version 1.2012. www.nccn.org/professionals/physician-gls/pdf/cns.pdf
  • 8
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987-996 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 9
    • 68149169111 scopus 로고    scopus 로고
    • Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: A Phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
    • Brandes AA, Tosoni A, Franceschi E et al. Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a Phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). Cancer Chemother. Pharmacol. 64, 769-775 (2009).
    • (2009) Cancer Chemother. Pharmacol. , vol.64 , pp. 769-775
    • Brandes, A.A.1    Tosoni, A.2    Franceschi, E.3
  • 10
    • 0015291143 scopus 로고
    • Tumor angiogenesis-quantitative method for histologic grading
    • Brem S, Folkman J, Cotran R. Tumor angiogenesis-quantitative method for histologic grading. J. Natl Cancer Inst. 48, 347-356 (1972).
    • (1972) J. Natl Cancer Inst. , vol.48 , pp. 347-356
    • Brem, S.1    Folkman, J.2    Cotran, R.3
  • 11
    • 0034757675 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas
    • Chaudhry IH, O'Donovan DG, Brenchley PEC et al. Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas. Histopathology 39, 409-415 (2001).
    • (2001) Histopathology , vol.39 , pp. 409-415
    • Chaudhry, I.H.1    O'Donovan, D.G.2    Pec, B.3
  • 12
    • 0038737156 scopus 로고    scopus 로고
    • Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma
    • Salmaggi A, Eoli M, Frigerio S et al. Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma. J. Neurooncol. 62, 297-303 (2003).
    • (2003) J. Neurooncol. , vol.62 , pp. 297-303
    • Salmaggi, A.1    Eoli, M.2    Frigerio, S.3
  • 13
    • 74049083639 scopus 로고    scopus 로고
    • Treatment of recurrent high-grade gliomas
    • Wen PY, Brandes AA. Treatment of recurrent high-grade gliomas. Curr. Opin. Neurol. 22, 657-664 (2009).
    • (2009) Curr. Opin. Neurol. , vol.22 , pp. 657-664
    • Wen, P.Y.1    Brandes, A.A.2
  • 14
    • 75449088610 scopus 로고    scopus 로고
    • FDA drug approval summary: Bevacizumab (Avastin®) as treatment of recurrent glioblastoma multiforme
    • Cohen MH, Shen YL, Keegan P et al. FDA drug approval summary: bevacizumab (Avastin®) as treatment of recurrent glioblastoma multiforme. Oncologist 14, 1131-1138 (2009).
    • (2009) Oncologist , vol.14 , pp. 1131-1138
    • Cohen, M.H.1    Shen, Y.L.2    Keegan, P.3
  • 15
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • Friedman HS, Prados MD, Wen PY et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J. Clin. Oncol. 27, 4733-4740 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 4733-4740
    • Friedman, H.S.1    Prados, M.D.2    Wen, P.Y.3
  • 16
    • 59949083263 scopus 로고    scopus 로고
    • Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
    • Kreisl TN, Kim L, Moore K et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J. Clin. Oncol. 27, 740-745 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 740-745
    • Kreisl, T.N.1    Kim, L.2    Moore, K.3
  • 17
    • 36049037819 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
    • Vredenburgh JJ, Desjardins A, Herndon JE et al. Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J. Clin. Oncol. 25, 4722-4729 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4722-4729
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon, J.E.3
  • 18
    • 84897447269 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab with fotemustine in recurrent glioblastoma: Fnal results of a multicenter study of AINO (Italian Association of Neuro-Oncology)
    • Soffetti R, Trevisan E, Ruda R et al. Phase II trial of bevacizumab with fotemustine in recurrent glioblastoma: fnal results of a multicenter study of AINO (Italian Association of Neuro-Oncology). Neuro Oncol. 29(15), 56-57 (2011).
    • (2011) Neuro Oncol. , vol.29 , Issue.15 , pp. 56-57
    • Soffetti, R.1    Trevisan, E.2    Ruda, R.3
  • 19
    • 84857373272 scopus 로고    scopus 로고
    • Bevacizumab and daily temozolomide for recurrent glioblastoma
    • Desjardins A, Reardon DA, Coan A et al. Bevacizumab and daily temozolomide for recurrent glioblastoma. Cancer 118, 1302-1312 (2012).
    • (2012) Cancer , vol.118 , pp. 1302-1312
    • Desjardins, A.1    Reardon, D.A.2    Coan, A.3
  • 20
    • 71649094684 scopus 로고    scopus 로고
    • Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: A Phase II study
    • Reardon DA, Desjardins A, Vredenburgh JJ et al. Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a Phase II study. Br. J. Cancer 101, 1986-1994 (2009).
    • (2009) Br. J. Cancer , vol.101 , pp. 1986-1994
    • Reardon, D.A.1    Desjardins, A.2    Vredenburgh, J.J.3
  • 22
    • 84903145427 scopus 로고    scopus 로고
    • A randomised Phase II study of carboplatin and bevacizumab in recurrent glioblastoma multiforme (CABARET)
    • Chicago, IL, USA, 31 May-4 June 2013
    • Maree K, Simes J, Wheeler H et al. A randomised Phase II study of carboplatin and bevacizumab in recurrent glioblastoma multiforme (CABARET). Presented at: 2013 American Society of Clinical Oncology Annual Meeting. Chicago, IL, USA, 31 May-4 June 2013.
    • Presented At: 2013 American Society of Clinical Oncology Annual Meeting
    • Maree, K.1    Simes, J.2    Wheeler, H.3
  • 23
    • 84903130313 scopus 로고    scopus 로고
    • A randomized Phase II study on bevacizumab versus bevacizumab plus lomustine versus lomustine single agent in recurrent glioblastoma: The Dutch BELOB study
    • Chicago, IL, USA, 31 May-4 June 2013
    • Taal W, Oosterkamp HM, WalenKamp L et al. A randomized Phase II study on bevacizumab versus bevacizumab plus lomustine versus lomustine single agent in recurrent glioblastoma: the Dutch BELOB study. Presented at: 2013 American Society of Clinical Oncology Annual Meeting. Chicago, IL, USA, 31 May-4 June 2013.
    • Presented At: 2013 American Society of Clinical Oncology Annual Meeting
    • Taal, W.1    Oosterkamp, H.M.2    Walenkamp, L.3
  • 25
    • 79951984402 scopus 로고    scopus 로고
    • Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
    • Lai A, Tran A, Nghiemphu PL et al. Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J. Clin. Oncol. 29, 142-148 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 142-148
    • Lai, A.1    Tran, A.2    Nghiemphu, P.L.3
  • 26
    • 84856806386 scopus 로고    scopus 로고
    • A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma
    • Narayana A, Gruber D, Kunnakkat S et al. A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma. J. Neurosurg. 116, 341-345 (2012).
    • (2012) J. Neurosurg. , vol.116 , pp. 341-345
    • Narayana, A.1    Gruber, D.2    Kunnakkat, S.3
  • 27
    • 84894114159 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab for newly diagnosed glioblastoma
    • Gilbert MR, Dignam JJ, Armstrong TC et al. A randomized trial of bevacizumab for newly diagnosed glioblastoma. N. Engl. J. Med. 370, 699-708 (2014).
    • (2014) N. Engl. J. Med. , vol.370 , pp. 699-708
    • Gilbert, M.R.1    Dignam, J.J.2    Armstrong, T.C.3
  • 28
    • 84894194756 scopus 로고    scopus 로고
    • Bevacizumab plus radiotherapy/temozolomide for newly diagnosed glioblastoma
    • Chinot OL, Wick W, Mason W et al. Bevacizumab plus radiotherapy/ temozolomide for newly diagnosed glioblastoma. N. Engl. J. Med. 370, 709-722 (2014).
    • (2014) N. Engl. J. Med. , vol.370 , pp. 709-722
    • Chinot, O.L.1    Wick, W.2    Mason, W.3
  • 29
    • 33749441325 scopus 로고    scopus 로고
    • Rapid vascular regrowth in tumors after reversal of VEGF inhibition
    • Mancuso MR, Davis R, Norberg SM et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J. Clin. Invest. 116, 2610-2621 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 2610-2621
    • Mancuso, M.R.1    Davis, R.2    Norberg, S.M.3
  • 30
    • 77956061453 scopus 로고    scopus 로고
    • Rebound tumour progression after the cessation of bevacizumab therapy in patients with recurrent high-grade glioma
    • Zuniga RM, Torcuator R, Jain R et al. Rebound tumour progression after the cessation of bevacizumab therapy in patients with recurrent high-grade glioma. J. Neuro-Oncol. 99, 237-242 (2010).
    • (2010) J. Neuro-Oncol. , vol.99 , pp. 237-242
    • Zuniga, R.M.1    Torcuator, R.2    Jain, R.3
  • 31
    • 79951983770 scopus 로고    scopus 로고
    • Disease course patterns after discontinuation of bevacizumab: Pooled analysis of randomized Phase III trials
    • Miles D, Harbeck N, Escudier B et al. Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized Phase III trials. J. Clin. Oncol. 29, 83-88 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 83-88
    • Miles, D.1    Harbeck, N.2    Escudier, B.3
  • 32
    • 0242468884 scopus 로고    scopus 로고
    • A Phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer
    • Cobleigh MA, Langmuir VK, Sledge GW et al. A Phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer. Semin. Oncol. 30, 117-124 (2003).
    • (2003) Semin. Oncol. , vol.30 , pp. 117-124
    • Cobleigh, M.A.1    Langmuir, V.K.2    Sledge, G.W.3
  • 33
    • 43449133278 scopus 로고    scopus 로고
    • Resistance to chemotherapy in cancer: A complex and integrated cellular response
    • Mellor HR, Callaghan R. Resistance to chemotherapy in cancer: a complex and integrated cellular response. Pharmacol. 81, 275-300 (2008).
    • (2008) Pharmacol. , vol.81 , pp. 275-300
    • Mellor, H.R.1    Callaghan, R.2
  • 34
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8, 592-603 (2008).
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 35
    • 68549092863 scopus 로고    scopus 로고
    • Goldie-Coldman and bevacizumab beyond disease progression
    • Giantonio BJ. Goldie-Coldman and bevacizumab beyond disease progression. Nat. Rev. Clin. Oncol. 6, 311-312 (2009).
    • (2009) Nat. Rev. Clin. Oncol. , vol.6 , pp. 311-312
    • Giantonio, B.J.1
  • 36
    • 84896739683 scopus 로고    scopus 로고
    • Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma
    • Lu KV, Bergers G. Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma. CNS Oncol. 2, 49-65 (2013).
    • (2013) CNS Oncol. , vol.2 , pp. 49-65
    • Lu, K.V.1    Bergers, G.2
  • 37
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307, 58-62 (2005).
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 38
    • 84878339732 scopus 로고    scopus 로고
    • Anti-angiogenic therapy in high-grade glioma (treatment and toxicity)
    • Taylor J, Gerstner ER. Anti-angiogenic therapy in high-grade glioma (treatment and toxicity). Curr. Treat. Options Neurol. 5(3), 328-337 (2013).
    • (2013) Curr. Treat. Options Neurol. , vol.5 , Issue.3 , pp. 328-337
    • Taylor, J.1    Gerstner, E.R.2
  • 39
    • 61349199518 scopus 로고    scopus 로고
    • An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma
    • Norden AD, Drappatz J, Muzikansky A et al. An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma. J. Neurooncol. 92, 149-155 (2009).
    • (2009) J. Neurooncol. , vol.92 , pp. 149-155
    • Norden, A.D.1    Drappatz, J.2    Muzikansky, A.3
  • 40
    • 45249118107 scopus 로고    scopus 로고
    • Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: Pitfalls in neurooncology
    • Brandes AA, Tosoni A, Spagnolli F et al. Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: pitfalls in neurooncology. Neuro Oncol. 10, 361-367 (2008).
    • (2008) Neuro Oncol. , vol.10 , pp. 361-367
    • Brandes, A.A.1    Tosoni, A.2    Spagnolli, F.3
  • 41
    • 43749094544 scopus 로고    scopus 로고
    • MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients
    • Brandes AA, Franceschi E, Tosoni A et al. MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients. J. Clin. Oncol. 26, 2192-2197 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2192-2197
    • Brandes, A.A.1    Franceschi, E.2    Tosoni, A.3
  • 42
    • 80855145598 scopus 로고    scopus 로고
    • Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy
    • Reardon DA, Desjardins A, Peters KB et al. Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. Cancer 117, 5351-5358 (2011).
    • (2011) Cancer , vol.117 , pp. 5351-5358
    • Reardon, D.A.1    Desjardins, A.2    Peters, K.B.3
  • 43
    • 79959812904 scopus 로고    scopus 로고
    • Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy
    • Reardon DA, Desjardins A, Peters K et al. Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. J. Neurooncol. 103, 371-379 (2011).
    • (2011) J. Neurooncol. , vol.103 , pp. 371-379
    • Reardon, D.A.1    Desjardins, A.2    Peters, K.3
  • 44
    • 67649092660 scopus 로고    scopus 로고
    • Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab
    • Quant EC, Norden AD, Drappatz J et al. Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab. Neuro Oncol. 11, 550-555 (2009).
    • (2009) Neuro Oncol. , vol.11 , pp. 550-555
    • Quant, E.C.1    Norden, A.D.2    Drappatz, J.3
  • 45
    • 70350142397 scopus 로고    scopus 로고
    • Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
    • Iwamoto FM, Abrey LE, Beal K et al. Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma. Neurology 73, 1200-1206 (2009).
    • (2009) Neurology , vol.73 , pp. 1200-1206
    • Iwamoto, F.M.1    Abrey, L.E.2    Beal, K.3
  • 46
    • 41649112610 scopus 로고    scopus 로고
    • Bevacizumab for recurrent malignant gliomas-effcacy, toxicity, and patterns of recurrence
    • Norden AD, Young GS, Setayesh K et al. Bevacizumab for recurrent malignant gliomas-effcacy, toxicity, and patterns of recurrence. Neurology 70, 779-787 (2008).
    • (2008) Neurology , vol.70 , pp. 779-787
    • Norden, A.D.1    Young, G.S.2    Setayesh, K.3
  • 47
    • 77953292729 scopus 로고    scopus 로고
    • The role of salvage reirradiation for malignant gliomas that progress on bevacizumab
    • Torcuator RG, Thind R, Patel M et al. The role of salvage reirradiation for malignant gliomas that progress on bevacizumab. J. Neurooncol. 97, 401-407.
    • J. Neurooncol. , vol.97 , pp. 401-407
    • Torcuator, R.G.1    Thind, R.2    Patel, M.3
  • 48
    • 84867900118 scopus 로고    scopus 로고
    • Bevacizumab continuation beyond initial bevacizumab progression among recurrent glioblastoma patients
    • Reardon DA, Herndon JE, Peters KB et al. Bevacizumab continuation beyond initial bevacizumab progression among recurrent glioblastoma patients. Br. J. Cancer 107, 1481-1487 (2012).
    • (2012) Br. J. Cancer , vol.107 , pp. 1481-1487
    • Reardon, D.A.1    Herndon, J.E.2    Peters, K.B.3
  • 49
    • 79952749187 scopus 로고    scopus 로고
    • New agents and new end points for recurrent gliomas
    • Brandes AA, Franceschi E. New agents and new end points for recurrent gliomas. J. Clin. Oncol. 29, e245-e246 (2011).
    • (2011) J. Clin. Oncol. , vol.29
    • Brandes, A.A.1    Franceschi, E.2
  • 50
    • 84859107015 scopus 로고    scopus 로고
    • Appropriate end-points for right results in the age of antiangiogenic agents: Future options for Phase II trials in patients with recurrent glioblastoma
    • Brandes AA, Franceschi E, Gorlia T et al. Appropriate end-points for right results in the age of antiangiogenic agents: future options for Phase II trials in patients with recurrent glioblastoma. Eur. J. Cancer 48, 896-903 (2012).
    • (2012) Eur. J. Cancer , vol.48 , pp. 896-903
    • Brandes, A.A.1    Franceschi, E.2    Gorlia, T.3
  • 51
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor T T, Sorensen AG, di Tomaso E et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11, 83-95 (2007).
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    Di Tomaso, E.3
  • 52
    • 36048955738 scopus 로고    scopus 로고
    • Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [F-18] fuorothymidine positron emission tomography: A pilot study
    • Chen W, Delaloye S, Silverman DHS et al. Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [F-18] fuorothymidine positron emission tomography: a pilot study. J. Clin. Oncol. 25, 4714-4721 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4714-4721
    • Chen, W.1    Delaloye, S.2    Dhs, S.3
  • 53
    • 77951625266 scopus 로고    scopus 로고
    • Updated response assessment criteria for high-grade gliomas: Response assessment in Neuro-Oncology Working Group
    • Wen PY, Macdonald DR, Reardon DA et al. Updated response assessment criteria for high-grade gliomas: response assessment in Neuro-Oncology Working Group. J. Clin. Oncol. 28, 1963-1972 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , pp. 1963-1972
    • Wen, P.Y.1    Macdonald, D.R.2    Reardon, D.A.3
  • 54
    • 53449086706 scopus 로고    scopus 로고
    • Frequently asked questions in the medical management of high-grade glioma: A short guide with practical answers
    • Stupp R, Hottinger AF, van den Bent MJ et al. Frequently asked questions in the medical management of high-grade glioma: a short guide with practical answers. Ann. Oncol. 19(Suppl. 7), vii209-vii216 (2008).
    • (2008) Ann. Oncol. , vol.19 , Issue.SUPPL. 7
    • Stupp, R.1    Hottinger, A.F.2    Van Den Bent, M.J.3
  • 55
    • 77956123282 scopus 로고    scopus 로고
    • Cardiovascular safety of VEGF-targeting therapies: Current evidence and handling strategies
    • Girardi F, Franceschi E, Brandes AA. Cardiovascular safety of VEGF-targeting therapies: current evidence and handling strategies. Oncologist 15, 683-694 (2010).
    • (2010) Oncologist , vol.15 , pp. 683-694
    • Girardi, F.1    Franceschi, E.2    Brandes, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.