Hormone therapy in ovarian granulosa cell tumors: A systematic review

Gynecologic Oncology

Volumn 134, Issue 1, 2014, Pages 196-205

  Van Meurs, Hannah S ^a   Van Lonkhuijzen, Luc R C W ^a   Limpens, Jacqueline ^b   Van Der Velden, Jacobus ^a   Buist, Marrije R ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Aromatase inhibitors; Granulosa cell tumor; Hormone therapy; Sex cord stromal tumor; Tamoxifen

Indexed keywords

AROMATASE INHIBITOR; TAMOXIFEN; ANASTROZOLE; DIETHYLSTILBESTROL; ESTRADIOL; ESTROGEN RECEPTOR; FOLLITROPIN RECEPTOR; GANIRELIX; GOSERELIN; HORMONE RECEPTOR; LETROZOLE; LEUPRORELIN; LUTEINIZING HORMONE RECEPTOR; MEDROXYPROGESTERONE ACETATE; MEGESTROL ACETATE; PROGESTERONE RECEPTOR; TESTOSTERONE;

CANCER HORMONE THERAPY; CANCER PATIENT; CANCER SURVIVAL; COCHRANE LIBRARY; EMBASE; GRANULOSA CELL TUMOR; HUMAN; MEDLINE; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROSPECTIVE STUDY; REVIEW; SYSTEMATIC REVIEW; TREATMENT OUTCOME; CANCER RADIOTHERAPY; CANCER RECURRENCE; CLINICAL EFFECTIVENESS; FEMALE; FOLLOW UP; GRANULOSA THECA CELL TUMOR; META ANALYSIS; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL (TOPIC); THECOMA; THERAPY EFFECT; TREATMENT RESPONSE;

AROMATASE INHIBITORS; GRANULOSA CELL TUMOR; HORMONE THERAPY; SEX CORD-STROMAL TUMOR; TAMOXIFEN;

ANTINEOPLASTIC AGENTS, HORMONAL; CLINICAL TRIALS AS TOPIC; FEMALE; GRANULOSA CELL TUMOR; HUMANS; OVARIAN NEOPLASMS;

EID: 84903193330     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2014.03.573     Document Type: Review

References (67)

1. H.S. van Meurs, M.C. Bleeker, J. van der Velden, L.I. Overbeek, G.G. Kenter, and M.R. Buist The incidence of endometrial hyperplasia and cancer in 1031 patients with a granulosa cell tumor of the ovary: long-term follow-up in a population-based cohort study Int J Gynecol Cancer 23 8 Oct 2013 1417 1422
2. S.T. Schumer, and S.A. Cannistra Granulosa cell tumor of the ovary J Clin Oncol 21 6 Mar 15 2003 1180 1189 (Pubitemid 46594151)
3. H.S. van Meurs, M.R. Buist, A.M. Westermann, G.S. Sonke, G.G. Kenter, and J. van der Velden Effectiveness of chemotherapy in measurable granulosa cell tumors: a retrospective study and review of literature Int J Gynecol Cancer 24 3 2014 496 505
4. E. Choan, R. Samant, M.F. Fung, T. Le, L. Hopkins, and M. Senterman Palliative radiotherapy for recurrent granulosa cell tumor of the ovary: a report of 3 cases with radiological evidence of response Gynecol Oncol 102 2 Aug 2006 406 410 (Pubitemid 44056264)
5. A.T. Evans III, T.A. Gaffey, G.D. Malkasian Jr., and J.F. Annegers Clinicopathologic review of 118 granulosa and 82 theca cell tumors Obstet Gynecol 55 2 Feb 1980 231 238 (Pubitemid 10174305)
6. G. Ohel, H. Kaneti, and J.G. Schenker Granulosa cell tumors in Israel: a study of 172 cases Gynecol Oncol 15 2 Apr 1983 278 286 (Pubitemid 13116674)
7. J.K. Wolf, J. Mullen, P.J. Eifel, T.W. Burke, C. Levenback, and D.M. Gershenson Radiation treatment of advanced or recurrent granulosa cell tumor of the ovary Gynecol Oncol 73 1 Apr 1999 35 41 (Pubitemid 29177596)
8. M.M. Alhilli, H.J. Long, K.C. Podratz, and J.N. Bakkum-Gamez Aromatase inhibitors in the treatment of recurrent ovarian granulosa cell tumors: brief report and review of the literature J Obstet Gynaecol Res 38 1 Jan 2012 340 344
9. L. Ameryckx, H.M. Fatemi, S.P. De, and J.J. Amy GnRH antagonist in the adjuvant treatment of a recurrent ovarian granulosa cell tumor: a case report Gynecol Oncol 99 3 Dec 2005 764 766 (Pubitemid 41693337)
10. A. Fishman, A.P. Kudelka, D. Tresukosol, C.L. Edwards, R.S. Freedman, and A.L. Kaplan et al. Leuprolide acetate for treating refractory or persistent ovarian granulosa cell tumor J Reprod Med 41 6 Jun 1996 393 396 (Pubitemid 26192479)
11. R.D. Hardy, J.G. Bell, C.J. Nicely, and G.C. Reid Hormonal treatment of a recurrent granulosa cell tumor of the ovary: case report and review of the literature Gynecol Oncol 96 3 Mar 2005 865 869 (Pubitemid 40255516)
12. M.A. Farinola, A.M. Gown, K. Judson, B.M. Ronnett, T.S. Barry, and S. Movahedi-Lankarani et al. Estrogen receptor alpha and progesterone receptor expression in ovarian adult granulosa cell tumors and Sertoli-Leydig cell tumors Int J Gynecol Pathol 26 4 Oct 2007 375 382 (Pubitemid 47476321)
13. K.M. Sjoquist, J. Martyn, R.J. Edmondson, and M.L. Friedlander The role of hormonal therapy in gynecological cancers-current status and future directions Int J Gynecol Cancer 21 7 Oct 2011 1328 1333
14. D. Moher, A. Liberati, J. Tetzlaff, and D.G. Altman Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement BMJ 339 2009 b2535
15. E.A. Eisenhauer, P. Therasse, J. Bogaerts, L.H. Schwartz, D. Sargent, and R. Ford et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1) Eur J Cancer 45 2 Jan 2009 228 247
16. D.M. Gershenson Treatment of ovarian cancer in young women Clin Obstet Gynecol 55 1 Mar 2012 65 74
17. R. Kepp Fundamentals of hormonal treatment in gynecology Ther Ggw 99 Apr 1960 182 186
18. C. Lauritzen Oestrogen substitution for a patient with a granulosa cell tumour Gynakol Prax 31 2007 480 (Pubitemid 47162673)
19. C.A. Brewer, and D. Shevlin Encouraging response of an advanced steroid-cell tumor to GnRH agonist therapy Obstet Gynecol 92 4 Pt 2 1998 Oct 661 663 (Pubitemid 28440783)
20. J.L. Powell, D.P. Dulaney, and B.C. Shiro Androgen-secreting steroid cell tumor of the ovary South Med J 93 12 Dec 2000 1201 1204
21. G. Cecchetto, A. Ferrari, G. Bernini, R. Alaggio, P. Collini, and C. Virgone et al. Sex cord stromal tumors of the ovary in children: a clinicopathological report from the Italian TREP project Pediatr Blood Cancer 56 7 Jul 1 2011 1062 1067
22. K.W. Schultze, and F.J. Krause Treatment by clomiphene and granulosa-cell tumor Geburtsh Frauenheilkd 25 1965 918 923
23. A.A. Kasperlik-Zaluska, L. Sikorowa, E. Ploch, P. Soszynski, W. Jeske, and B. Migdalska et al. Ectopic ACTH syndrome due to bilateral ovarian androblastoma with double, gynandroblastic differentiation in one ovary Eur J Obstet Gynecol Reprod Biol 52 3 Dec 30 1993 223 228 (Pubitemid 24028518)
24. I.A. Al-Badawi, P.M. Brasher, P. Ghatage, J.G. Nation, A. Schepansky, and G.C. Stuart Postoperative chemotherapy in advanced ovarian granulosa cell tumors Int J Gynecol Cancer 12 1 Jan 2002 119 123 (Pubitemid 34202960)
25. P. Pautier, M. Gutierrez-Bonnaire, A. Rey, I. Sillet-Bach, C. Chevreau, and P. Kerbrat et al. Combination of bleomycin, etoposide, and cisplatin for the treatment of advanced ovarian granulosa cell tumors Int J Gynecol Cancer 18 3 May 2008 446 452 (Pubitemid 351668317)
26. M.F. Mostafa, N. El-etreby, and N. Awad Retrospective analysis evaluating ovarian cancer cases presented at the clinical oncology department, Alexandria University Alex J Med 48 2012 353 360
27. M.R. Soules, G.E. Abraham, and E.H. Bossen The steroid profile of a virilizing ovarian tumor Obstet Gynecol 52 1 Jul 1978 73 78 (Pubitemid 8354036)
28. J. Jarabak, and A. Talerman Virilization due to a metastasizing granulosa cell tumor Int J Gynecol Pathol 2 3 1983 316 324 (Pubitemid 14176993)
29. B.R. Witt, G.C. Wolf, C.J. Wainwright, and I.H. Thorneycroft Endocrine function of granulosa cell tumors in vivo Gynecol Obstet Invest 33 1 1992 59 64
30. D. Pectasides, N. Alevizakos, and A.E. Athanassiou Cisplatin-containing regimen in advanced or recurrent granulosa cell tumours of the ovary Ann Oncol 3 4 Apr 1992 316 318
31. M.J. Donate-Moreno, H. Pastor-Navarro, P. Carrion-Lopez, A. Pascual-Martin, A.S. Salinas-Sanchez, and J.G. Lorenzo-Romero et al. Late recurrence of ovarian granulosa cell tumor at the retroperitoneal and renal hilum level in a single-kidney patient - case report Eur J Gynaecol Oncol 28 6 2007 487 490
32. C.A. Verhagen, Q.G. van Hoesel, C.P. Schijf, and P.H. DeMulder The management of granulosa cell tumor of the ovary - a case history Ann Oncol 7 5 Jul 1996 521 524 (Pubitemid 26232960)
33. A. Auranen, J. Sundstrom, J. Ijas, and S. Grenman Prognostic factors of ovarian granulosa cell tumor: a study of 35 patients and review of the literature Int J Gynecol Cancer 17 5 Sep 2007 1011 1018 (Pubitemid 47414826)
34. J. Bringer, J. Marchal, N. Bressot, G. Barneon, J. Saussol, and C. Jaffiol et al. The inhibiting effect of danazol on plasma estradiol in a castrated woman with a metastatic granulosa-theca cell tumor Acta Endocrinol (Copenh) 97 1981
35. J. Dubuc-Lissoir, M.J. Berthiaume, G. Boubez, N.T. Van, and G. Allaire Bone metastasis from a granulosa cell tumor of the ovary Gynecol Oncol 83 2 Nov 2001 400 404 (Pubitemid 33033086)
36. M.M. Pascale, M. Pugeat, M. Roberts, H. Rousset, H. Dechaud, and N. Dutrieux-Berger et al. Androgen suppressive effect of GnRH agonist in ovarian hyperthecosis and virilizing tumours Clin Endocrinol (Oxf) 41 5 Nov 1994 571 576 (Pubitemid 24336857)
37. P. Savage, D. Constenla, C. Fisher, J.H. Shepherd, D.P. Barton, and P. Blake et al. Granulosa cell tumours of the ovary: demographics, survival and the management of advanced disease Clin Oncol (R Coll Radiol) 10 4 1998 242 245 (Pubitemid 28454544)
38. R. Tamura, Y. Yokoyama, T. Yanagita, Y. Matsumura, K. Abe, and R. Taniguchi et al. Presentation of two patients with malignant granulosa cell tumors, with a review of the literature World J Surg Oncol 10 2012 185
39. S.J. Wilson, B.K. Young, M. Katz, S. Kammerman, J. Epstein, and B. Bigelow A gonadotropin-responsive virilizing granulosa tumor Diagn Gynecol Obstet 2 4 1980 275 281
40. R. Rosario, M. Wilson, W.T. Cheng, K. Payne, P.A. Cohen, and P. Fong et al. Adult granulosa cell tumours (GCT): clinicopathological outcomes including FOXL2 mutational status and expression Gynecol Oncol 131 2 Nov 2013 325 329
41. L.E. Rebstock, L. Leufflen, A. Leroux, V. Harter, J.L. Verhaeghe, and F. Marchal Granulosa cell tumor of the ovary: retrospective study of 17 cases Gynecol Obstet Fertil 2014 [Epub ahead of print]
42. A. Abdul Munem, B. Al-Bahrani, I. Mehdi, A. Kamona, and A.M. Nadas Aromatase inhibitors - a viable option for recurrent granulosa cell tumour of ovary: overview and case report J Pak Med Assoc 62 5 May 2012 505 507
43. E. Briasoulis, V. Karavasilis, and N. Pavlidis Megestrol activity in recurrent adult type granulosa cell tumour of the ovary Ann Oncol 8 8 Aug 1997 811 812 (Pubitemid 27397910)
44. K.D. Crew, M.H. Cohen, D.H. Smith, A.D. Tiersten, N.M. Feirt, and D.L. Hershman Long natural history of recurrent granulosa cell tumor of the ovary 23 years after initial diagnosis: a case report and review of the literature Gynecol Oncol 96 1 Jan 2005 235 240 (Pubitemid 39614236)
45. S.A. Freeman, and S.C. Modesitt Anastrozole therapy in recurrent ovarian adult granulosa cell tumors: a report of 2 cases Gynecol Oncol 103 2 Nov 2006 755 758 (Pubitemid 44602195)
46. R. Isaacs, G. Forgeson, and S. Allan Progestagens for granulosa cell tumours of the ovary Br J Cancer 65 1 Jan 1992 140
47. A. Kauppila, M. Bangah, H. Burger, and H. Martikainen GnRH agonist analog therapy in advanced/recurrent granulosa cell tumors: further evidence of a role of inhibin in monitoring response to treatment Gynecol Endocrinol 6 4 Dec 1992 271 274 (Pubitemid 23079509)
48. S. Keskin, E. Bengisu, S. Tuzlali, and A. Aydiner Complete response in a patient with granulosa cell tumor treated with a combination of leuprolide and tamoxifen Onkologie 35 7-8 2012 451 453
49. H.J. Kim, S.C. Lee, S.B. Bae, K.W. Kwon, C.K. Kim, and N.S. Lee et al. GnRH agonist therapy in a patient with recurrent ovarian granulosa cell tumors J Korean Med Sci 24 3 Jun 2009 535 538
50. J. Korach, T. Perri, M. Beiner, T. Davidzon, E. Fridman, and G. Ben-Baruch Promising effect of aromatase inhibitors on recurrent granulosa cell tumors Int J Gynecol Cancer 19 5 Jul 2009 830 833
51. S.T. Malik, and M.L. Slevin Medroxyprogesterone acetate (MPA) in advanced granulosa cell tumours of the ovary - a new therapeutic approach? Br J Cancer 63 3 1991 Mar 410 411
52. H. Martikainen, J. Penttinen, I. Huhtaniemi, and A. Kauppila Gonadotropin-releasing hormone agonist analog therapy effective in ovarian granulosa cell malignancy Gynecol Oncol 35 3 1989 Dec 406 408 (Pubitemid 20025912)
53. G.L. Maxwell, A.P. Soisson, and P. Miles Failure of gonadotropin releasing hormone therapy in patients with metastatic ovarian sex cord stromal tumors Oncology 51 4 1994 Jul 356 359 (Pubitemid 24185138)
54. D. Teoh, R. Freedman, and P.T. Soliman Nearly 30 years of treatment for recurrent granulosa cell tumor of the ovary: a case report and review of the literature Case Rep Oncol 3 1 2010 14 18
55. M.A. Livshits, and A.A. Cheremnykh Successful treatment of a recurrence of an ovarian granulosa cell tumor (1 case) Vopr Onkol 16 1 1970 110 111
56. H.R. Kourie, J. Kattan, J. Antoun, and F. Sleilaty Letrozole efficacy in the treatment of granulosa cell tumor of the ovary: a case report Onkologie 36 9 2013 498 500
57. F. Modugno, R. Laskey, A.L. Smith, C.L. Andersen, P. Haluska, and S. Oesterreich Hormone response in ovarian cancer: time to reconsider as a clinical target? Endocr Relat Cancer 19 6 2012 Dec R255 R279
58. D.W. Sommeijer, K.M. Sjoquist, and M. Friedlander Hormonal treatment in recurrent and metastatic gynaecological cancers: a review of the current literature Curr Oncol Rep 15 6 2013 Dec 541 548
59. M. Alexiadis, N. Eriksson, S. Jamieson, M. Davis, A.E. Drummond, and S. Chu et al. Nuclear receptor profiling of ovarian granulosa cell tumors Horm Cancer 2 3 Jun 2011 157 169
60. A. Bowman, H. Gabra, S.P. Langdon, A. Lessells, M. Stewart, and A. Young et al. CA125 response is associated with estrogen receptor expression in a phase II trial of letrozole in ovarian cancer: identification of an endocrine-sensitive subgroup Clin Cancer Res 8 7 2002 Jul 2233 2239 (Pubitemid 34753595)
61. S.P. Shah, M. Kobel, J. Senz, R.D. Morin, B.A. Clarke, and K.C. Wiegand et al. Mutation of FOXL2 in granulosa-cell tumors of the ovary N Engl J Med 360 26 Jun 25 2009 2719 2729
62. M. Park, E. Shin, M. Won, J.H. Kim, H. Go, and H.L. Kim et al. FOXL2 interacts with steroidogenic factor-1 (SF-1) and represses SF-1-induced CYP17 transcription in granulosa cells Mol Endocrinol 24 5 2010 May 1024 1036
63. N.I. Fleming, K.C. Knower, K.A. Lazarus, P.J. Fuller, E.R. Simpson, and C.D. Clyne Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter PLoS One 5 12 2010 e14389
64. L. Gibson, D. Lawrence, C. Dawson, and J. Bliss Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women Cochrane Database Syst Rev 4 2009 [CD003370]
65. A. Garrett, and M.A. Quinn Hormonal therapies and gynaecological cancers Best Pract Res Clin Obstet Gynaecol 22 2 2008 Apr 407 421 (Pubitemid 351292329)
66. Australian New Zealand Clinical Trials Registry https://www.anzctr.org. au/Trial/Registration/TrialReview.aspx?id=335968
67. ClinicalTrials.gov. A service of the U.S. National Institutes of Health http://clinicaltrials.gov/ct2/show/NCT01770301