TC1(C8orf4) regulates hematopoietic stem/progenitor cells and hematopoiesis

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Jung, Yusun ^a   Kim, Minsung ^a   Soh, Hyunsu ^a   Lee, Soyoung ^a   Kim, Jungtae ^a   Park, Surim ^a   Song, Kyuyoung ^a   Lee, Inchul ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; TC1 PROTEIN; UNCLASSIFIED DRUG; 1810011O10RIK PROTEIN, MOUSE; MESSENGER RNA; TUMOR PROTEIN;

ADULT; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL LINEAGE; CELL POPULATION; COLONY FORMING UNIT; CONTROLLED STUDY; ERYTHROCYTE COUNT; ERYTHROCYTE VOLUME; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LYMPHOID CELL; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEM CELL EXPANSION; WILD TYPE; YOUNG ADULT; ANIMAL; BONE MARROW; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; ENZYME IMMUNOASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETICS; HL 60 CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BONE MARROW; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HL-60 CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; NEOPLASM PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84903175724     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100311     Document Type: Article

References (36)

1. Clements WK, Traver D (2013) Signalling pathways that control vertebrate haematopoietic stem cell specification. Nat Rev Immunol 13(5): 336-348.
2. Doulatov S, Notta F, Laurenti E, Dick JE (2012) Hematopoiesis: a human perspective. Cell Stem Cell 10(2): 120-136.
3. Seita J, Weissman IL (2010) Hematopoietic stem cell: self-renewal versus differentiation. Wiley Interdiscip Rev Syst Biol Med 2(6): 640-653.
4. Mercer EM, Lin YC, Murre C (2011) Factors and networks that underpin early hematopoiesis. Semin Immunol 23(5): 317-325.
5. Luc S, Buza-Vidas N, Jacobsen SE (2008) Delineating the cellular pathways of hematopoietic lineage commitment. Semin Immunol 20(4): 213-220.
6. Wilson NK, Foster SD, Wang X, Knezevic K, Schütte J, et al. (2010) Combinatorial transcriptional control in blood stem/progenitor cells: genomewide analysis of ten major transcriptional regulators. Cell Stem Cell 7(4): 532-544.
7. Metcalf D (2008) Hematopoietic cytokines. Blood 111(2): 485-491.
8. Rossi L, Lin KK, Boles NC, Yang L, King KY, et al. (2012) Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell 11(3): 302-317.
9. Chua EL, Young L, Wu WM, Turtle JR, Dong Q (2000) Cloning of TC-1 (C8orf4), a novel gene found to be overexpressed in thyroid cancer. Genomics 69(3): 342-347.
10. Sunde M, McGrath KC, Young L, Matthews JM, Chua EL, et al. (2004) TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer. Cancer Res 64(8): 2766-2773. (Pubitemid 38500614)
11. Friedman JB, Brunschwig EB, Platzer P, Wilson K, Markowitz SD (2004) C8orf4 is a transforming growth factor B induced transcript downregulated in metastatic colon cancer. Int J Cancer 111(1): 72-75. (Pubitemid 38859285)
12. Kim B, Koo H, Yang S, Bang S, Jung Y, et al. (2006) TC1(C8orf4) correlates with Wnt/beta-catenin target genes and aggressive biological behavior in gastric cancer. Clin Cancer Res 12(11): 3541-3548.
13. Yang ZQ, Streicher KL, Ray ME, Abrams J, Ethier SP (2006) Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer. Cancer Res 66(24): 11632-11643. (Pubitemid 46094174)
14. Walter MJ, Payton JE, Ries RE, Deshmukh H, Zhao Y, et al. (2009) Acquired copy number alterations in adult acute myeloid leukemia genomes. Proc Natl Acad Sci U SA 106(31): 12950-12955.
15. Zhang J, Gao Y, Zhao X, Guan M, Zhang W, et al. (2011) Investigation of copy-number variations of C8orf4 in hematological malignancies. Med Oncol 28: S647-S652.
16. Kim J, Kim Y, Kim HT, Kim DW, Ha Y, et al. (2009) TC1(C8orf4) is a novel endothelial inflammatory regulator enhancing NF-kappaB activity. J Immunol 183(6): 3996-4002.
17. Jung Y, Bang S, Choi K, Kim E, Kim Y, et al. (2006) TC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby. Cancer Res 66(2): 723-728. (Pubitemid 43165934)
18. Kim Y, Kim J, Park J, Bang S, Jung Y, et al. (2006) TC1(C8orf4) is upregulated by IL-1beta/TNF-alpha and enhances proliferation of human follicular dendritic cells. FEBS Lett 580(14): 3519-3524. (Pubitemid 43795901)
19. Park J, Jung Y, Kim J, Kim KY, Ahn SG, et al. (2007) TC1(C8orf4) is upregulated by cellular stress and mediates heat shock response. Biochem Biophys Res Commun 360(2): 447-452. (Pubitemid 47030363)
20. Chung SJ, Armasu SM, Biernacka JM, Anderson KJ, Lesnick TG, et al. (2012) Genomic determinants of motor and cognitive outcomes in Parkinson's disease. Parkinsonism Relat Disord 18(7): 881-886.
21. Bouchon A, Facchetti F, Weigand MA, Colonna M (2001) TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 410(6832): 1103-1107. (Pubitemid 32391042)
22. Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121(7): 1109-1121. (Pubitemid 40884400)
23. Oguro H, Ding L, Morrison SJ (2013) SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors. Cell Stem Cell 13(1): 102-116.
24. Biermann H, Pietz B, Dreier R, Schmid KW, Sorg C, et al. (1999) Murine leukocytes with ring-shaped nuclei include granulocytes, monocytes, and their precursors. J Leukoc Biol 65(2): 217-231. (Pubitemid 29077015)
25. Rosenbauer F, Tenen DG (2007) Transcription factors in myeloid development: balancing differentiation with transformation. Nat Rev Immunol 7(2): 105-117. (Pubitemid 46174858)
26. Rieger MA, Hoppe PS, Smejkal BM, Eitelhuber AC, Schroeder T (2009) Hematopoietic cytokines can instruct lineage choice. Science 325(5937): 217-218.
27. Mossadegh-Keller N, Sarrazin S, Kandalla PK, Espinosa L, Stanley ER, et al. (2013) M-CSF instructs myeloid lineage fate in single haematopoietic stem cells. Nature 497(7448): 239-243.
28. Lento W, Congdon K, Voermans C, Kritzik M, Reya T (2013) Wnt signaling in normal and malignant hematopoiesis. Cold Spring Harb Perspect Biol 5(2).
29. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4): 663-676. (Pubitemid 44233629)
30. Ruiz G, Rosenmann M, Cortes A (2004) Thermal acclimation and seasonal variations of erythrocyte size in the Andean mouse Phyllotis xanthopygus rupestris. Comp Biochem Physiol A Mol Integr Physiol 139(4): 405-409. (Pubitemid 39642897)
31. Beutler E, West C (2005) Hematologic differences between African-Americans and whites: the roles of iron deficiency and alpha-thalassemia on hemoglobin levels and mean corpuscular volume. Blood 106(2): 740-745. (Pubitemid 40981275)
32. Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, et al. (2009) A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet 41(11): 1182-1190.
33. Ganesh SK, Zakai NA, van Rooij FJ, Soranzo N, Smith AV, et al. (2009) Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet 41(11): 1191-1198.
34. Patel KV, Semba RD, Ferrucci L, Newman AB, Fried LP, et al. (2010) Red cell distribution width and mortality in older adults: ameta-analysis. J Gerontol A Biol Sci Med Sci 65(3): 258-265.
35. Montagnana M, Cervellin G, Meschi T, Lippi G (2012) The role of red blood cell distribution width in cardiovascular and thrombotic disorders. Clin Chem Lab Med 50(4): 635-641.
36. Delano MJ, Scumpia PO, Weinstein JS, Coco D, Nagaraj S, et al. (2007) MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med 204(6): 1463-1474. (Pubitemid 46919883)