Engineering the MEP pathway enhanced ajmalicine biosynthesis

Biotechnology and Applied Biochemistry

Volumn 61, Issue 3, 2014, Pages 249-255

  Chang, Kai ^a,b   Qiu, Fei ^a   Chen, Min ^a   Zeng, Lingjiang ^a   Liu, Xiaoqiang ^a   Yang, Chunxian ^a   Lan, Xiaozhong ^c   Wang, Qiang ^d   Liao, Zhihua ^a  

^a SOUTHWEST UNIVERSITY   (China)

^b State Administration of Grain   (China)

^c TIBET UNIVERSITY   (China)

^d YANGTZE RIVER SCIENTIFIC RESEARCH INSTITUTE   (China)

Author keywords

alkaloids; Catharanthus roseus; DXR; MECS; pathway engineering; STR

Indexed keywords

ALKALOIDS; BIOCHEMISTRY; GENES;

CATHARANTHUS ROSEUS; DXR; MECS; PATHWAY ENGINEERINGS; STR;

BIOSYNTHESIS;

1 DEOXYXYLULOSE 5 PHOSPHATE REDUCTOISOMERASE; 2 METHYLERYTHRITIOL 2,4 CYCLODIPHOSPHATE SYNTHASE; 2 METHYLERYTHRITOL 4 PHOSPHATE; AJMALICINE; ANTHERAXANTIN; BETA CAROTENE; CHLOROPHYLL A; ESSENTIAL OIL; INDOLE ALKALOID; ISOPRENOID; OXIDOREDUCTASE; PHOSPHATE; SITOSTEROL; SOLANESOL; STRICTOSIDINE SYNTHASE; SYNTHETASE; TRYPTAMINE; UNCLASSIFIED DRUG; XANTHOPHYLL; 2-C-METHYLERYTHRITOL 4-PHOSPHATE; DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE; ERYTHRITOL; LYASE; RAUWOLFIA ALKALOID; STRICTOSIDINE SYNTHETASE; SUGAR PHOSPHATE; TRANSFERASE;

ARTICLE; CATHARANTHUS ROSEUS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SYNTHESIS; GENE EXPRESSION; GENE OVEREXPRESSION; HAIRY ROOT CULTURE; METABOLIC ENGINEERING; METABOLIC FLUX ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; TAXUS; TRANSGENE; ANALOGS AND DERIVATIVES; CATHARANTHUS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN ENGINEERING;

CATHARANTHUS ROSEUS; TAXUS;

CARBON-NITROGEN LYASES; CATHARANTHUS; ERYTHRITOL; MOLECULAR STRUCTURE; PHOSPHORUS-OXYGEN LYASES; PROTEIN ENGINEERING; SECOLOGANIN TRYPTAMINE ALKALOIDS; SUGAR PHOSPHATES; TAXUS; TRANSFERASES;

EID: 84903169384     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1176     Document Type: Article

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