β-catenin is a valuable marker for differential diagnosis of osteoblastoma and osteosarcoma

Human Pathology

Volumn 45, Issue 7, 2014, Pages 1459-1465

  Wan, Yang ^a   Zhao, Wendi ^a   Jiang, Yan ^a   Liu, Debao ^a   Meng, Gang ^a   Cai, Yongping ^a  

^a ANHUI UNIVERSITY   (China)

Author keywords

Immunohistochemistry; Osteoblastoma; Osteosarcoma; Wnt; catenin

Indexed keywords

BETA CATENIN;

ADOLESCENT; ADULT; ARTICLE; BONE TUMOR; CELLULAR DISTRIBUTION; CHILD; CLINICAL ARTICLE; CYTOPLASM; DIFFERENTIAL DIAGNOSIS; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; OSTEOBLAST; OSTEOBLASTOMA; OSTEOSARCOMA; SCHOOL CHILD; TUMOR RECURRENCE; YOUNG ADULT;

IMMUNOHISTOCHEMISTRY; OSTEOBLASTOMA; OSTEOSARCOMA; WNT; Β-CATENIN;

ADOLESCENT; ADULT; BETA CATENIN; BONE NEOPLASMS; CELL NUCLEUS; CYTOPLASM; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MALE; OSTEOBLASTOMA; OSTEOSARCOMA; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84903168635     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2014.02.022     Document Type: Article

References (23)

1. K.I. Atesok, B.A. Alman, and E.H. Schemitsch et al. Osteoid osteoma and osteoblastoma J Am Acad Orthop Surg 19 2011 678 689
2. R. Gorlick, K. Janeway, and S. Lessnick et al. Children's Oncology Group's 2013 blueprint for research: bone tumors Pediatr Blood Cancer 60 2013 1009 1015
3. D.R. Lucas, K.K. Unni, and R.A. McLeod et al. Osteoblastoma: clinicopathologic study of 306 cases Hum Pathol 25 1994 117 134 (Pubitemid 24079631)
4. F. Bertoni, K.K. Unni, and R.A. McLeod et al. Osteosarcoma resembling osteoblastoma Cancer 55 1985 416 426 (Pubitemid 15152816)
5. F. Bertoni, P. Bacchini, and D. Donati et al. Osteoblastoma-like osteosarcoma. The Rizzoli Institute experience Mod Pathol 6 1993 707 716 (Pubitemid 2014239)
6. Z.H. El-Badawi, E.M. Muhammad, and H.H. Noaman Role of immunohistochemical cyclo-oxygenase-2 (COX-2) and osteocalcin in differentiating between osteoblastomas and osteosarcomas Malays J Pathol 34 2012 15 23
7. A. Hosono, U. Yamaguchi, and A. Makimoto et al. Utility of immunohistochemical analysis for cyclo-oxygenase 2 in the differential diagnosis of osteoblastoma and osteosarcoma J Clin Pathol 60 2007 410 414 (Pubitemid 46596561)
8. R. Baron, and M. Kneissel WNT signaling in bone homeostasis and disease: from human mutations to treatments Nat Med 19 2013 179 192
9. C. Niehrs The complex world of WNT receptor signalling Nat Rev Mol Cell Biol 13 2012 767 779
10. J.B. Regard, Z. Zhong, and B.O. Williams et al. Wnt signaling in bone development and disease: making stronger bone with Wnts Cold Spring Harb Perspect Biol 2012 a007997
11. Y. Cai, A.B. Mohseny, and M. Karperien et al. Inactive Wnt/beta-catenin pathway in conventional high-grade osteosarcoma J Pathol 220 2010 24 33
12. T.L. Ng, A.M. Gown, and T.S. Barry et al. Nuclear beta-catenin in mesenchymal tumors Mod Pathol 18 2005 68 74 (Pubitemid 40128097)
13. K. Chen, S. Fallen, and H.O. Abaan et al. Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival Pediatr Blood Cancer 51 2008 349 355
14. B.H. Hoang, T. Kubo, and J.H. Healey et al. Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma Int J Cancer 109 2004 106 111 (Pubitemid 38160669)
15. R.C. Haydon, A. Deyrup, and A. Ishikawa et al. Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma Int J Cancer 102 2002 338 342 (Pubitemid 35265873)
16. K. Iwaya, H. Ogawa, and M. Kuroda et al. Cytoplasmic and/or nuclear staining of beta-catenin is associated with lung metastasis Clin Exp Metastasis 20 2003 525 529 (Pubitemid 37297180)
17. A.M. Cleton-Jansen, J.K. Anninga, and I.H. Briaire-de Bruijn Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways Br J Cancer 101 2009 2064
18. S. Piperdi, L. Austin-Page, and D. Geller et al. Beta-catenin does not confer tumorigenicity when introduced into partially transformed human mesenchymal stem cells Sarcoma 2012 2012 164803
19. A. Jeanes, C.J. Gottardi, and A.S. Yap Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene 27 2008 6920 6929
20. J.W. Carlson, and C.D. Fletcher Immunohistochemistry for beta-catenin in the differential diagnosis of spindle cell lesions: analysis of a series and review of the literature Histopathology 51 2007 509 514 (Pubitemid 47437826)
21. S.C. Huang, K.F. Ng, and T.S. Yeh et al. Clinicopathological analysis of beta-catenin and Axin-1 in solid pseudopapillary neoplasms of the pancreas Ann Surg Oncol 19 Suppl 3 2012 S438 S446
22. K.K. Mak, M.H. Chen, and T.F. Day et al. Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation Development 133 2006 3695 3707 (Pubitemid 44614291)
23. D.Y. Dao, J.H. Jonason, and Y. Zhang et al. Cartilage-specific beta-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development J Bone Miner Res 27 2012 1680 1694