Ectopic over-expression of miR-429 induces mesenchymal-to-epithelial transition (MET) and increased drug sensitivity in metastasizing ovarian cancer cells

Gynecologic Oncology

Volumn 134, Issue 1, 2014, Pages 96-103

  Wang, Lijuan ^a   Mezencev, Roman ^a   Švajdler, Marián ^b,c   Benigno, Benedict B ^d   McDonald, John F ^a,d  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b BIOPTICAL LABORATORY   (Czech Republic)

^c L PASTEUR UNIVERSITY HOSPITAL   (Slovakia)

^d Ovarian Cancer Institute   (United States)

Author keywords

EMT; MET; Metastasis; MicroRNAs; Ovarian cancer

Indexed keywords

CA 125 ANTIGEN; CARBOPLATIN; MICRORNA; MICRORNA 429; PACLITAXEL; UNCLASSIFIED DRUG;

AGED; ARTICLE; ASCITES; CANCER CHEMOTHERAPY; CANCER STAGING; CASE REPORT; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MESENCHYMAL TO EPITHELIAL TRANSITION; MULTIPLE CYCLE TREATMENT; OVARIAN CANCER CELL LINE; OVARY CANCER; PRIMARY CELL LINE; PRIORITY JOURNAL;

EMT; MET; METASTASIS; MICRORNAS; OVARIAN CANCER;

AGED; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CISPLATIN; DRUG SCREENING ASSAYS, ANTITUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; MICE; MICE, NUDE; MICRORNAS; OVARIAN NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84903158882     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2014.04.055     Document Type: Article

References (30)

1. A. Jemal, F. Bray, M.M. Center, J. Ferlay, E. Ward, and D. Forman Global cancer statistics CA Cancer J Clin 61 2011 69 90
2. B.A. Goff, L. Mandel, H.G. Muntz, and C.H. Melancon Ovarian carcinoma diagnosis Cancer 89 2000 2068 2075
3. R.F. Ozols Treatment goals in ovarian cancer Int J Gynecol Cancer 15 Suppl. 1 2005 3 11 (Pubitemid 40696471)
4. S. Zhang, C. Balch, M.W. Chan, H.C. Lai, D. Matei, and J.M. Schilder et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors Cancer Res 68 2008 4311 4320
5. A.B. Alvero, R. Chen, H.H. Fu, M. Montagna, P.E. Schwartz, and T. Rutherford et al. Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance Cell Cycle 8 2009 158 166
6. L. Wang, R. Mezencev, N.J. Bowen, L.V. Matyunina, and J.F. McDonald Isolation and characterization of stem-like cells from a human ovarian cancer cell line Mol Cell Biochem 363 2012 257 268
7. P.B. Gupta, T.T. Onder, G. Jiang, K. Tao, C. Kuperwasser, and R.A. Weinberg et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening Cell 138 2009 645 659
8. R. Mezencev, L. Wang, and J.F. McDonald Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening J Ovarian Res 5 2012 30
9. S.P. McDermott, and M.S. Wicha Targeting breast cancer stem cells Mol Oncol 4 2010 404 419
10. S. Clayton, and S.A. Mousa Therapeutics formulated to target cancer stem cells: is it in our future? Cancer Cell Int 11 2011 7
11. J. Monteiro, and R. Fodde Cancer stemness and metastasis: therapeutic consequences and perspectives Eur J Cancer 46 2010 1198 1203
12. K.H. Yew, J. Crow, J. Hirst, Z. Pressetto, and A.K. Godwin Epimorphin-induced MET sensitizes ovarian cancer cells to platinum PLoS ONE 8 2013 e72637
13. S. Lamouille, D. Subramanyam, R. Blelloch, and R. Derynck Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs Curr Opin Cell Biol 25 2013 200 207
14. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
15. M.R. Fabian, N. Sonenberg, and W. Filipowicz Regulation of mRNA translation and stability by microRNAs Annu Rev Biochem 79 2010 351 379
16. J. Chen, L. Wang, L.V. Matyunina, C.G. Hill, and J.F. McDonald Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells Gynecol Oncol 121 2011 200 205
17. N. Jabbari, A.N. Reavis, and J.F. McDonald Sequence variation among members of the miR-200 microRNA family is correlated with variation in the ability to induce hallmarks of mesenchymal-epithelial transition in ovarian cancer cells J Ovarian Res 7 2014 12
18. S.K. Singh, C. Hawkins, I.D. Clarke, J.A. Squire, J. Bayani, and T. Hide et al. Identification of human brain tumour initiating cells Nature 432 2004 396 401 (Pubitemid 39551674)
19. M. Al-Hajj, M.S. Wicha, A. Benito-Hernandez, S.J. Morrison, and M.F. Clarke Prospective identification of tumorigenic breast cancer cells Proc Natl Acad Sci U S A 100 2003 3983 3988 (Pubitemid 36418143)
20. R. Mezencev, and J.F. McDonald Subcutenous xenografts of human T-lineage acute lymphoblastic leukemia Jurkat cells in nude mice In Vivo 25 2011 603 607
21. R.N. Buick, R. Pullano, and J.M. Trent Comparative properties of five human ovarian adenocarcinoma cell lines Cancer Res 45 1985 3668 3676 (Pubitemid 15226443)
22. T.C. Hamilton, R.C. Young, W.M. McKoy, K.R. Grotzinger, J.A. Green, and E.W. Chu et al. Characterization of a human ovarian carcinoma cell line (NIH:OVCAR-3) with androgen and estrogen receptors Cancer Res 43 1983 5379 5389 (Pubitemid 14230154)
23. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics, 2013 CA Cancer J Clin 63 2013 11 30
24. M. Dean, T. Fojo, and S. Bates Tumour stem cells and drug resistance Nat Rev Cancer 5 2005 275 284 (Pubitemid 40488633)
25. M. Diehn, and M.F. Clarke Cancer stem cells and radiotherapy: new insights into tumor radioresistance J Natl Cancer Inst 98 2006 1755 1757 (Pubitemid 46017927)
26. X. Li, M.T. Lewis, J. Huang, C. Gutierrez, C.K. Osborne, and M.F. Wu et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy J Natl Cancer Inst 100 2008 672 679
27. D. Chen, Y. Zhang, J. Wang, J. Chen, C. Yang, and K. Cai et al. MicroRNA-200c overexpression inhibits tumorigenicity and metastasis of CD117 + CD44 + ovarian cancer stem cells by regulating epithelial-mesenchymal transition J Ovarian Res 6 2013 50
28. P.A. Gregory, A.G. Bert, E.L. Paterson, S.C. Barry, A. Tsykin, and G. Farshid et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 Nat Cell Biol 10 2008 593 601 (Pubitemid 351627379)
29. M. Korpal, and Y. Kang The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis RNA Biol 5 2008 115 119
30. E.L. Paterson, N. Kolesnikoff, P.A. Gregory, A.G. Bert, Y. Khew-Goodall, and G.J. Goodall The microRNA-200 family regulates epithelial to mesenchymal transition Sci World J 8 2008 901 904