-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008 GLOBOCAN 2008
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127(12), 2893-2917 (2010
-
(2010)
Int. J. Cancer
, vol.127
, Issue.12
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
84893663818
-
Targeted therapy in renal cell carcinoma: Moving from molecular agents to specific immunotherapy
-
Bedke J, Gouttefangeas C, Singh-Jasuja H, Stevanovic S, Behnes CL, Stenzl A. Targeted therapy in renal cell carcinoma: Moving from molecular agents to specific immunotherapy. World J. Urol. 32(1), 31-38 (2014
-
(2014)
World J. Urol
, vol.32
, Issue.1
, pp. 31-38
-
-
Bedke, J.1
Gouttefangeas, C.2
Singh-Jasuja, H.3
Stevanovic, S.4
Behnes, C.L.5
Stenzl, A.6
-
3
-
-
34547720636
-
Unexpected abundance of HLA class II presented peptides in primary renal cell carcinomas
-
Dengjel J, Nastke MD, Gouttefangeas C et al. Unexpected abundance of HLA class II presented peptides in primary renal cell carcinomas. Clin. Cancer Res. 12(14 Pt 1), 4163-4170 (2006
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.14 PART 1
, pp. 4163-4170
-
-
Dengjel, J.1
Nastke, M.D.2
Gouttefangeas, C.3
-
4
-
-
0024539002
-
Unexplained spontaneous regression and alpha-interferon as treatment for metastatic renal carcinoma
-
Oliver RT, Nethersell AB, Bottomley JM. Unexplained spontaneous regression and alpha-interferon as treatment for metastatic renal carcinoma. Br. J. Urol. 63(2), 128-131 (1989
-
(1989)
Br. J. Urol
, vol.63
, Issue.2
, pp. 128-131
-
-
Oliver, R.T.1
Nethersell, A.B.2
Bottomley, J.M.3
-
5
-
-
77955493600
-
EAU guidelines on renal cell carcinoma: The 2010 update
-
Ljungberg B, Cowan NC, Hanbury DC et al. EAU guidelines on renal cell carcinoma: The 2010 update. Eur. Urol. 58(3), 398-406 (2010
-
(2010)
Eur. Urol
, vol.58
, Issue.3
, pp. 398-406
-
-
Ljungberg, B.1
Cowan, N.C.2
Hanbury, D.C.3
-
6
-
-
23044514578
-
Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis
-
Donnenberg VS, Donnenberg AD. Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis. J. Clin. Pharmacol. 45(8), 872-877 (2005
-
(2005)
J. Clin. Pharmacol
, vol.45
, Issue.8
, pp. 872-877
-
-
Donnenberg, V.S.1
Donnenberg, A.D.2
-
7
-
-
33947420385
-
Prognostic significance of multidrug-resistance protein (MDR-1) in renal clear cell carcinomas: A five year follow-up analysis
-
Mignogna C, Staibano S, Altieri V et al. Prognostic significance of multidrug-resistance protein (MDR-1) in renal clear cell carcinomas: A five year follow-up analysis. BMC Cancer 6, 293 (2006
-
(2006)
BMC Cancer
, vol.6
, pp. 293
-
-
Mignogna, C.1
Staibano, S.2
Altieri, V.3
-
8
-
-
84862874665
-
Second-line systemic therapy for the treatment of metastatic renal cell cancer
-
Kruck S, Bedke J, Kuczyk MA, Merseburger AS. Second-line systemic therapy for the treatment of metastatic renal cell cancer. Expert Rev. Anticancer Ther. 12(6), 777-785 (2012
-
(2012)
Expert Rev. Anticancer Ther
, vol.12
, Issue.6
, pp. 777-785
-
-
Kruck, S.1
Bedke, J.2
Kuczyk, M.A.3
Merseburger, A.S.4
-
9
-
-
0033514050
-
Interferon-Alpha and survival in metastatic renal carcinoma: Early results of a randomised controlled trial
-
Medical Research Council Renal Cancer Collaborators
-
Interferon-Alpha and survival in metastatic renal carcinoma: Early results of a randomised controlled trial. Medical Research Council Renal Cancer Collaborators. Lancet 353(9146), 14-17 (1999
-
(1999)
Lancet
, vol.353
, Issue.9146
, pp. 14-17
-
-
-
10
-
-
18944385751
-
Immunotherapy for advanced renal cell cancer
-
Coppin C, Porzsolt F, Awa A, Kumpf J, Coldman A, Wilt T. Immunotherapy for advanced renal cell cancer. Cochrane Database Syst. Rev. 1, CD001425 (2005
-
(2005)
Cochrane Database Syst. Rev
, vol.1
-
-
Coppin, C.1
Porzsolt, F.2
Awa, A.3
Kumpf, J.4
Coldman, A.5
Wilt, T.6
-
11
-
-
0028929682
-
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
-
Fyfe G, Fisher RI, Rosenberg SA, Sznol M, Parkinson DR, Louie AC. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J. Clin. Oncol. 13(3), 688-696 (1995
-
(1995)
J. Clin. Oncol
, vol.13
, Issue.3
, pp. 688-696
-
-
Fyfe, G.1
Fisher, R.I.2
Rosenberg, S.A.3
Sznol, M.4
Parkinson, D.R.5
Louie, A.C.6
-
12
-
-
0042914703
-
Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
-
Yang JC, Sherry RM, Steinberg SM et al. Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer. J. Clin. Oncol. 21(16), 3127-3132 (2003
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.16
, pp. 3127-3132
-
-
Yang, J.C.1
Sherry, R.M.2
Steinberg, S.M.3
-
13
-
-
21044442672
-
Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer
-
Atkins M, Regan M, McDermott D et al. Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer. Clin. Cancer Res. 11(10), 3714-3721 (2005
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.10
, pp. 3714-3721
-
-
Atkins, M.1
Regan, M.2
McDermott, D.3
-
14
-
-
78650630648
-
The high-dose aldesleukin (hd il-2 SELECT' trial in patients with metastatic renal cell carcinoma (mRCC)
-
Suppl.), Abstract 4514
-
McDermott DF, Ghebremichael MS, Signoretti S et al. The high-dose aldesleukin (HD IL-2) 'SELECT' trial in patients with metastatic renal cell carcinoma (mRCC). J. Clin. Oncol. 28(15 Suppl.), Abstract 4514 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.15
-
-
McDermott, D.F.1
Ghebremichael, M.S.2
Signoretti, S.3
-
15
-
-
33644784733
-
IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients
-
Ahmadzadeh M, Rosenberg SA. IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients. Blood 107(6), 2409-2414 (2006
-
(2006)
Blood
, vol.107
, Issue.6
, pp. 2409-2414
-
-
Ahmadzadeh, M.1
Rosenberg, S.A.2
-
16
-
-
34247524959
-
Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer
-
van der Vliet HJ, Koon HB, Yue SC et al. Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer. Clin. Cancer Res. 13(7), 2100-2108 (2007
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.7
, pp. 2100-2108
-
-
Van Der Vliet, H.J.1
Koon, H.B.2
Yue, S.C.3
-
17
-
-
77952300540
-
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
-
Escudier B, Bellmunt J, Negrier S et al. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival. J. Clin. Oncol. 28(13), 2144-2150 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.13
, pp. 2144-2150
-
-
Escudier, B.1
Bellmunt, J.2
Negrier, S.3
-
18
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363(5), 411-422 (2010
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
19
-
-
79958264390
-
Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma
-
Schuster SJ, Neelapu SS, Gause BL et al. Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma. J. Clin. Oncol. 29(20), 2787-2794 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, Issue.20
, pp. 2787-2794
-
-
Schuster, S.J.1
Neelapu, S.S.2
Gause, B.L.3
-
20
-
-
79957831345
-
GP100 peptide vaccine and interleukin-2 in patients with advanced melanoma
-
Schwartzentruber DJ, Lawson DH, Richards JM et al. gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N. Engl. J. Med. 364(22), 2119-2127 (2011
-
(2011)
N. Engl. J. Med
, vol.364
, Issue.22
, pp. 2119-2127
-
-
Schwartzentruber, D.J.1
Lawson, D.H.2
Richards, J.M.3
-
22
-
-
0026322151
-
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
-
van der Bruggen P, Traversari C, Chomez P et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 254(5038), 1643-1647 (1991
-
(1991)
Science
, vol.254
, Issue.5038
, pp. 1643-1647
-
-
Van Der Bruggen, P.1
Traversari, C.2
Chomez, P.3
-
23
-
-
77953760053
-
Can vaccination or tyrosine kinase inhibitor therapy play a role in the adjuvant treatment of renal cell carcinoma?. Expert Rev
-
Brookman-May S, May M, Gilfrich C, Wieland WF, Burger M. Can vaccination or tyrosine kinase inhibitor therapy play a role in the adjuvant treatment of renal cell carcinoma?. Expert Rev. Anticancer Ther. 10(6), 813-823 (2010
-
(2010)
Anticancer Ther
, vol.10
, Issue.6
, pp. 813-823
-
-
Brookman-May, S.1
May, M.2
Gilfrich, C.3
Wieland, W.F.4
Burger, M.5
-
24
-
-
33745247366
-
Immunologic and Clin. Responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients
-
Wierecky J, Muller MR, Wirths S et al. Immunologic and Clin. responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients. Cancer Res. 66(11), 5910-5918 (2006
-
(2006)
Cancer Res
, vol.66
, Issue.11
, pp. 5910-5918
-
-
Wierecky, J.1
Muller, M.R.2
Wirths, S.3
-
25
-
-
84871503916
-
Clinical and immunological monitoring of a multi-peptide vaccination trial in patients with stage III renal cell carcinoma
-
e76-ea
-
Bedke J, Laske K, Feyerabend S et al. Clinical and immunological monitoring of a multi-peptide vaccination trial in patients with stage III renal cell carcinoma. Eur. Urol. Supplements 11(1), e76-ea (2012
-
(2012)
Eur. Urol. Supplements
, vol.11
, Issue.1
-
-
Bedke, J.1
Laske, K.2
Feyerabend, S.3
-
26
-
-
84864662070
-
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
-
Walter S, Weinschenk T, Stenzl A et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat. Med. 18(8), 1254-1261 (2012
-
(2012)
Nat. Med
, vol.18
, Issue.8
, pp. 1254-1261
-
-
Walter, S.1
Weinschenk, T.2
Stenzl, A.3
-
28
-
-
78651292217
-
Allele frequency net: A database and online repository for immune gene frequencies in worldwide populations
-
Database issue
-
Gonzalez-Galarza FF, Christmas S, Middleton D, Jones AR. Allele frequency net: A database and online repository for immune gene frequencies in worldwide populations. Nucleic Acids Res. 39(Database issue), D913-D919 (2011
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Gonzalez-Galarza, F.F.1
Christmas, S.2
Middleton, D.3
Jones, A.R.4
-
29
-
-
10744230275
-
Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III, randomised controlled trial
-
Jocham D, Richter A, Hoffmann L et al. Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III, randomised controlled trial. Lancet 363(9409), 594-599 (2004
-
(2004)
Lancet
, vol.363
, Issue.9409
, pp. 594-599
-
-
Jocham, D.1
Richter, A.2
Hoffmann, L.3
-
30
-
-
70350010317
-
Immunotherapeutic strategies in kidney cancer-when TKIs are not enough
-
Biswas S, Eisen T. Immunotherapeutic strategies in kidney cancer-when TKIs are not enough. Nat. Rev. Clin. Oncol. 6(8), 478-487 (2009
-
(2009)
Nat. Rev. Clin. Oncol
, vol.6
, Issue.8
, pp. 478-487
-
-
Biswas, S.1
Eisen, T.2
-
31
-
-
46749085802
-
An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: A multicentre, open-label, randomised Phase III trial
-
Wood C, Srivastava P, Bukowski R et al. An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: A multicentre, open-label, randomised Phase III trial. Lancet 372(9633), 145-154 (2008
-
(2008)
Lancet
, vol.372
, Issue.9633
, pp. 145-154
-
-
Wood, C.1
Srivastava, P.2
Bukowski, R.3
-
32
-
-
0036214288
-
Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses
-
Srivastava P. Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. 20, 395-425 (2002
-
(2002)
Annu. Rev. Immunol
, vol.20
, pp. 395-425
-
-
Srivastava, P.1
-
33
-
-
0034608387
-
Cross-presentation of glycoprotein 96-Associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis
-
Singh-Jasuja H, Toes RE, Spee P et al. Cross-presentation of glycoprotein 96-Associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis. J. Exp. Med. 191(11), 1965-1974 (2000
-
(2000)
J. Exp. Med
, vol.191
, Issue.11
, pp. 1965-1974
-
-
Singh-Jasuja, H.1
Toes, R.E.2
Spee, P.3
-
34
-
-
46749131796
-
Vitespen: A vaccine for renal cancer?
-
Yang JC. Vitespen: A vaccine for renal cancer?. Lancet 372(9633), 92-93 (2008
-
(2008)
Lancet
, vol.372
, Issue.9633
, pp. 92-93
-
-
Yang, J.C.1
-
35
-
-
78349284842
-
Vaccination of metastatic renal cancer patients with MVA-5T4: A randomized, double-blind, placebo-controlled Phase III study
-
Amato RJ, Hawkins RE, Kaufman HL et al. Vaccination of metastatic renal cancer patients with MVA-5T4: A randomized, double-blind, placebo-controlled Phase III study. Clin. Cancer Res. 16(22), 5539-5547 (2010
-
(2010)
Clin. Cancer Res
, vol.16
, Issue.22
, pp. 5539-5547
-
-
Amato, R.J.1
Hawkins, R.E.2
Kaufman, H.L.3
-
36
-
-
0029903794
-
Metastasis-Associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells
-
Carsberg CJ, Myers KA, Stern PL. Metastasis-Associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells. Int. J. Cancer 68(1), 84-92 (1996
-
(1996)
Int. J. Cancer
, vol.68
, Issue.1
, pp. 84-92
-
-
Carsberg, C.J.1
Myers, K.A.2
Stern, P.L.3
-
37
-
-
0025109257
-
Immunohistological distribution of 5T4 antigen in normal and malignant tissues
-
Southall PJ, Boxer GM, Bagshawe KD, Hole N, Bromley M, Stern PL. Immunohistological distribution of 5T4 antigen in normal and malignant tissues. Br. J. Cancer 61(1), 89-95 (1990
-
(1990)
Br. J. Cancer
, vol.61
, Issue.1
, pp. 89-95
-
-
Southall, P.J.1
Boxer, G.M.2
Bagshawe, K.D.3
Hole, N.4
Bromley, M.5
Stern, P.L.6
-
38
-
-
79960359817
-
A Phase II study testing the safety and activity of AGS-003 as an immunotherapeutic in subjects with newly diagnosed advanced stage renal cell carcinoma (RCC in combination with sunitinib
-
Suppl.), Abstract 4514
-
Amin A, Dudek A, Logan T et al. A Phase II study testing the safety and activity of AGS-003 as an immunotherapeutic in subjects with newly diagnosed advanced stage renal cell carcinoma (RCC) in combination with sunitinib. J. Clin. Oncol. 28(15 Suppl.), Abstract 4514 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.15
-
-
Amin, A.1
Dudek, A.2
Logan, T.3
-
39
-
-
84880944039
-
Prolonged survival with personalized immunotherapy (AGS-003 in combination with sunitinib in unfavorable risk metastatic RCC (mRCC)
-
Abstract 357
-
Amin A, Dudek A, Logan T et al. Prolonged survival with personalized immunotherapy (AGS-003) in combination with sunitinib in unfavorable risk metastatic RCC (mRCC). J. Clin. Oncol. 31(Suppl. 6), Abstract 357 (2013
-
(2013)
J. Clin. Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Amin, A.1
Dudek, A.2
Logan, T.3
-
41
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson JH, Heimberger AB, Archer GE et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J. Clin. Oncol. 28(31), 4722-4729 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.31
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
-
42
-
-
24944546501
-
Immunomonitoring tumor-specific T cells in delayed-Type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome
-
de Vries IJ, Bernsen MR, Lesterhuis WJ et al. Immunomonitoring tumor-specific T cells in delayed-Type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome. J. Clin. Oncol. 23(24), 5779-5787 (2005
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.24
, pp. 5779-5787
-
-
De Vries, I.J.1
Bernsen, M.R.2
Lesterhuis, W.J.3
-
43
-
-
58149179532
-
Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients
-
Finke JH, Rini B, Ireland J et al. Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients. Clin. Cancer Res. 14(20), 6674-6682 (2008
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.20
, pp. 6674-6682
-
-
Finke, J.H.1
Rini, B.2
Ireland, J.3
-
44
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N. Engl. J. Med. 356(2), 115-124 (2007
-
(2007)
N. Engl. J. Med
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
45
-
-
34248194231
-
Tregs and rethinking cancer immunotherapy
-
Curiel TJ. Tregs and rethinking cancer immunotherapy. J. Clin. Invest. 117(5), 1167-1174 (2007
-
(2007)
J. Clin. Invest
, vol.117
, Issue.5
, pp. 1167-1174
-
-
Curiel, T.J.1
-
46
-
-
58149332680
-
Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma
-
Kusmartsev S, Su Z, Heiser A et al. Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin. Cancer Res. 14(24), 8270-8278 (2008
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.24
, pp. 8270-8278
-
-
Kusmartsev, S.1
Su, Z.2
Heiser, A.3
-
47
-
-
14944360112
-
Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4
-
Probst HC, McCoy K, Okazaki T, Honjo T, van den Broek M. Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. Nat. Immunol. 6(3), 280-286 (2005
-
(2005)
Nat. Immunol
, vol.6
, Issue.3
, pp. 280-286
-
-
Probst, H.C.1
McCoy, K.2
Okazaki, T.3
Honjo, T.4
Van Den Broek, M.5
-
48
-
-
84877940678
-
Trial watch: Peptide vaccines in cancer therapy
-
Vacchelli E, Martins I, Eggermont A et al. Trial watch: Peptide vaccines in cancer therapy. Oncoimmunology 1(9), 1557-1576 (2012
-
(2012)
Oncoimmunology
, vol.1
, Issue.9
, pp. 1557-1576
-
-
Vacchelli, E.1
Martins, I.2
Eggermont, A.3
-
50
-
-
67049156789
-
Novel multi-peptide vaccination in Hla-A2+ hormone sensitive patients with biochemical relapse of prostate cancer
-
Feyerabend S, Stevanovic S, Gouttefangeas C et al. Novel multi-peptide vaccination in Hla-A2+ hormone sensitive patients with biochemical relapse of prostate cancer. Prostate 69(9), 917-927 (2009
-
(2009)
Prostate
, vol.69
, Issue.9
, pp. 917-927
-
-
Feyerabend, S.1
Stevanovic, S.2
Gouttefangeas, C.3
-
51
-
-
1642578298
-
Dr william coley and tumour regression: A place in history or in the future
-
Hoption Cann SA, van Netten JP, van Netten C. Dr William Coley and tumour regression: A place in history or in the future. Postgrad. Med. J. 79(938), 672-680 (2003
-
(2003)
Postgrad. Med. J.
, vol.79
, Issue.938
, pp. 672-680
-
-
Hoption Cann, S.A.1
Van Netten, J.P.2
Van Netten, C.3
-
52
-
-
84855172987
-
Toll-like receptor 4 activation in cancer progression and therapy
-
Oblak A, Jerala R. Toll-like receptor 4 activation in cancer progression and therapy. Clin. Dev. Immunol. 2011, 609579 (2011
-
(2011)
Clin. Dev. Immunol
, vol.2011
, pp. 609579
-
-
Oblak, A.1
Jerala, R.2
-
53
-
-
33646234040
-
Granulocyte-macrophage-colony-stimulating factor and other cytokines: As adjuncts to cancer immunotherapy, stem cell transplantation, and vaccines
-
Arellano M, EK Waller. Granulocyte-macrophage-colony-stimulating factor and other cytokines: As adjuncts to cancer immunotherapy, stem cell transplantation, and vaccines. Curr. Hematol. Rep. 3(6), 424-431 (2004
-
(2004)
Curr. Hematol. Rep
, vol.3
, Issue.6
, pp. 424-431
-
-
Arellano, M.1
Waller, E.K.2
-
54
-
-
33847258205
-
Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
-
Parmiani G, Castelli C, Pilla L, Santinami M, Colombo MP, Rivoltini L. Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann. Oncol. 18(2), 226-232 (2007
-
(2007)
Ann. Oncol
, vol.18
, Issue.2
, pp. 226-232
-
-
Parmiani, G.1
Castelli, C.2
Pilla, L.3
Santinami, M.4
Colombo, M.P.5
Rivoltini, L.6
-
55
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting antitumor immunity
-
Dranoff G, Jaffee E, Lazenby A et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting antitumor immunity. Proc. Natl Acad. Sci. USA 90(8), 3539-3543 (1993
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, Issue.8
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
-
56
-
-
0034047619
-
Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand
-
Mach N, Gillessen S, Wilson SB, Sheehan C, Mihm M, Dranoff G. Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand. Cancer Res. 60(12), 3239-3246 (2000
-
(2000)
Cancer Res
, vol.60
, Issue.12
, pp. 3239-3246
-
-
Mach, N.1
Gillessen, S.2
Wilson, S.B.3
Sheehan, C.4
Mihm, M.5
Dranoff, G.6
-
57
-
-
0031570843
-
Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells
-
Qin Z, Noffz G, Mohaupt M, Blankenstein T. Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells. J. Immunol. 159(2), 770-776 (1997
-
(1997)
J. Immunol
, vol.159
, Issue.2
, pp. 770-776
-
-
Qin, Z.1
Noffz, G.2
Mohaupt, M.3
Blankenstein, T.4
-
58
-
-
4344590947
-
High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells
-
Serafini P, Carbley R, Noonan KA, Tan G, Bronte V, Borrello I. High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells. Cancer Res. 64(17), 6337-6343 (2004
-
(2004)
Cancer Res
, vol.64
, Issue.17
, pp. 6337-6343
-
-
Serafini, P.1
Carbley, R.2
Noonan, K.A.3
Tan, G.4
Bronte, V.5
Borrello, I.6
-
59
-
-
84880936480
-
Single-dose cyclophosphamide synergizes with immune responses to the renal cell cancer vaccine IMA901
-
Walter S, Weinschenk T, Reinhardt C, Singh-Jasuja H. Single-dose cyclophosphamide synergizes with immune responses to the renal cell cancer vaccine IMA901. Oncoimmunology 2(1), e22246 (2013
-
(2013)
Oncoimmunology
, vol.2
, Issue.1
-
-
Walter, S.1
Weinschenk, T.2
Reinhardt, C.3
Singh-Jasuja, H.4
-
60
-
-
84881233953
-
Cyclophosphamide induces a type I interferon-Associated sterile inflammatory response signature in cancer patients' blood cells: Implications for cancer chemoimmunotherapy
-
Moschella F, Torelli GF, Valentini M et al. Cyclophosphamide induces a type I interferon-Associated sterile inflammatory response signature in cancer patients' blood cells: Implications for cancer chemoimmunotherapy. Clin. Cancer Res. 19(15), 4249-4261 (2013
-
(2013)
Clin. Cancer Res
, vol.19
, Issue.15
, pp. 4249-4261
-
-
Moschella, F.1
Torelli, G.F.2
Valentini, M.3
-
61
-
-
0022597114
-
Induction of cell-mediated immunity to autologous melanoma cells and regression of metastases after treatment with a melanoma cell vaccine preceded by cyclophosphamide
-
Berd D, Maguire HC Jr, Mastrangelo MJ. Induction of cell-mediated immunity to autologous melanoma cells and regression of metastases after treatment with a melanoma cell vaccine preceded by cyclophosphamide. Cancer Res. 46(5), 2572-2577 (1986
-
(1986)
Cancer Res
, vol.46
, Issue.5
, pp. 2572-2577
-
-
Berd, D.1
Maguire Jr., H.C.2
Mastrangelo, M.J.3
-
62
-
-
33847368549
-
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
-
Ghiringhelli F, Menard C, Puig PE et al. Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol CII 56(5), 641-648 (2007
-
(2007)
Cancer Immunol CII
, vol.56
, Issue.5
, pp. 641-648
-
-
Ghiringhelli, F.1
Menard, C.2
Puig, P.E.3
-
63
-
-
79551514818
-
Cyclophosphamide induces differentiation of Th17 cells in cancer patients
-
Viaud S, Flament C, Zoubir M et al. Cyclophosphamide induces differentiation of Th17 cells in cancer patients. Cancer Res. 71(3), 661-665 (2011
-
(2011)
Cancer Res
, vol.71
, Issue.3
, pp. 661-665
-
-
Viaud, S.1
Flament, C.2
Zoubir, M.3
-
64
-
-
84888059687
-
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide
-
Viaud S, Saccheri F, Mignot G et al. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 342(6161), 971-976 (2013
-
(2013)
Science
, vol.342
, Issue.6161
, pp. 971-976
-
-
Viaud, S.1
Saccheri, F.2
Mignot, G.3
-
65
-
-
84878589185
-
Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma
-
Sevko A, Sade-Feldman M, Kanterman J et al. Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma. J. Invest. Dermatol. 133(6), 1610-1619 (2013
-
(2013)
J. Invest. Dermatol
, vol.133
, Issue.6
, pp. 1610-1619
-
-
Sevko, A.1
Sade-Feldman, M.2
Kanterman, J.3
-
66
-
-
47049127786
-
Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses
-
Hipp MM, Hilf N, Walter S et al. Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. Blood 111(12), 5610-5620 (2008
-
(2008)
Blood
, vol.111
, Issue.12
, pp. 5610-5620
-
-
Hipp, M.M.1
Hilf, N.2
Walter, S.3
-
67
-
-
84878758972
-
Reduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors
-
Stehle F, Schulz K, Fahldieck C et al. Reduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors. J. Biol. Chem. 288(23), 16334-16347 (2013
-
(2013)
J. Biol. Chem
, vol.288
, Issue.23
, pp. 16334-16347
-
-
Stehle, F.1
Schulz, K.2
Fahldieck, C.3
-
68
-
-
63549105681
-
Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
-
Ko JS, Zea AH, Rini BI et al. Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin. Cancer Res. 15(6), 2148-2157 (2009
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.6
, pp. 2148-2157
-
-
Ko, J.S.1
Zea, A.H.2
Rini, B.I.3
-
69
-
-
84860780501
-
Combined vaccine+axitinib therapy yields superior antitumor efficacy in a murine melanoma model
-
Bose A, Lowe DB, Rao A, Storkus WJ. Combined vaccine+axitinib therapy yields superior antitumor efficacy in a murine melanoma model. Melanoma Res. 22(3), 236-243 (2012
-
(2012)
Melanoma Res
, vol.22
, Issue.3
, pp. 236-243
-
-
Bose, A.1
Lowe, D.B.2
Rao, A.3
Storkus, W.J.4
-
70
-
-
82755183572
-
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised Phase 3 trial
-
Rini BI, Escudier B, Tomczak P et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised Phase 3 trial. Lancet 378(9807), 1931-1939 (2011
-
(2011)
Lancet
, vol.378
, Issue.9807
, pp. 1931-1939
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
-
71
-
-
84903181506
-
Combination of sunitinib with antitumor vaccination inhibits T cell priming and requires careful scheduling to achieve productive immunotherapy
-
Jaini R, Rayman P, Cohen PA, Finke JH, Tuohy VK. Combination of sunitinib with antitumor vaccination inhibits T cell priming and requires careful scheduling to achieve productive immunotherapy. Int. J. Cancer (2013
-
(2013)
Int. J. Cancer
-
-
Jaini, R.1
Rayman, P.2
Cohen, P.A.3
Finke, J.H.4
Tuohy, V.K.5
-
72
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12(4), 252-264 (2012
-
(2012)
Nat. Rev. Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
73
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363(8), 711-723 (2010
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'day, S.J.2
McDermott, D.F.3
-
74
-
-
37349072460
-
Ipilimumab (antiCTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis
-
Yang JC, Hughes M, Kammula U et al. Ipilimumab (antiCTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis. J. Immunother. 30(8), 825-830 (2007
-
(2007)
J. Immunother
, vol.30
, Issue.8
, pp. 825-830
-
-
Yang, J.C.1
Hughes, M.2
Kammula, U.3
-
75
-
-
84903208746
-
CA184-043: A randomized, multicenter, double-blind Phase 3 trial comparing overall survival (OS) in patients (pts) with post-docetaxel castration-resistant prostate cancer (CRPC) and bone metastases treated with ipilimumab (ipi) vs placebo (pbo), each following single-dose radiotherapy (RT
-
Amsterdam, The Netherlands, 27 September-1 October
-
Gerritsen WR,, Kwon ED,, Fizazi K et al. CA184-043: A randomized, multicenter, double-blind Phase 3 trial comparing overall survival (OS) in patients (pts) with post-docetaxel castration-resistant prostate cancer (CRPC) and bone metastases treated with ipilimumab (ipi) vs placebo (pbo), each following single-dose radiotherapy (RT). Presented at: European Cancer Congress. Amsterdam, The Netherlands, 27 September-1 October 2013
-
(2013)
Presented at: European Cancer Congress
-
-
Gerritsen, W.R.1
Kwon, E.D.2
Fizazi, K.3
-
76
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife BT, Pauken KE, Eagar TN et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat. Immunother. 10(11), 1185-1192 (2009
-
(2009)
Nat. Immunother
, vol.10
, Issue.11
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
-
77
-
-
77950283280
-
Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma
-
Hino R, Kabashima K, Kato Y et al. Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer 116(7), 1757-1766 (2010
-
(2010)
Cancer
, vol.116
, Issue.7
, pp. 1757-1766
-
-
Hino, R.1
Kabashima, K.2
Kato, Y.3
-
78
-
-
84862859820
-
Safety, activity, and immune correlates of antiPD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR et al. Safety, activity, and immune correlates of antiPD-1 antibody in cancer. N. Engl. J. Med. 366(26), 2443-2454 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
80
-
-
84873353521
-
Bispecific antibodies and trispecific immunocytokines for targeting the immune system against cancer: Preparing for the future
-
Fournier P, Schirrmacher V. Bispecific antibodies and trispecific immunocytokines for targeting the immune system against cancer: Preparing for the future. BioDrugs 27(1), 35-53 (2013.
-
(2013)
BioDrugs
, vol.27
, Issue.1
, pp. 35-53
-
-
Fournier, P.1
Schirrmacher, V.2
|