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Volumn 42, Issue 7, 2014, Pages 1174-1179

Effects of proton pump inhibitors on metformin pharmacokinetics and pharmacodynamics

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; METFORMIN; PANTOPRAZOLE; RABEPRAZOLE; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; PROTON PUMP INHIBITOR;

EID: 84903141985     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.055616     Document Type: Article
Times cited : (38)

References (29)
  • 2
  • 3
    • 0035955922 scopus 로고    scopus 로고
    • Prevalence of gastrointestinal symptoms associated with diabetes mellitus: A population-based survey of 15,000 adults
    • Bytzer P, Talley NJ, Leemon M, Young LJ, Jones MP, and Horowitz M (2001) Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults. Arch Intern Med 161:1989-1996.
    • (2001) Arch Intern Med , vol.161 , pp. 1989-1996
    • Bytzer, P.1    Talley, N.J.2    Leemon, M.3    Young, L.J.4    Jones, M.P.5    Horowitz, M.6
  • 4
    • 0036127907 scopus 로고    scopus 로고
    • GI symptoms in diabetes mellitus are associated with both poor glycemic control and diabetic complications
    • Bytzer P, Talley NJ, Hammer J, Young LJ, Jones MP, and Horowitz M (2002) GI symptoms in diabetes mellitus are associated with both poor glycemic control and diabetic complications. Am J Gastroenterol 97:604-611.
    • (2002) Am J Gastroenterol , vol.97 , pp. 604-611
    • Bytzer, P.1    Talley, N.J.2    Hammer, J.3    Young, L.J.4    Jones, M.P.5    Horowitz, M.6
  • 6
    • 84855656082 scopus 로고    scopus 로고
    • Proton pump inhibitor therapy associated with lower glycosylated hemoglobin levels in type 2 diabetes
    • Crouch MA, Mefford IN, and Wade EU (2012) Proton pump inhibitor therapy associated with lower glycosylated hemoglobin levels in type 2 diabetes. J Am Board Fam Med 25:50-54.
    • (2012) J Am Board Fam Med , vol.25 , pp. 50-54
    • Crouch, M.A.1    Mefford, I.N.2    Wade, E.U.3
  • 7
    • 84903218319 scopus 로고    scopus 로고
    • Influence of dissolution media pH and USP1 basket speed on erosion and disintegration characteristics of immediate release metformin hydrochloride tablets
    • Epub ahead of print
    • Desai D, Wong B, Huang Y, Tang D, Hemenway J, Paruchuri S, Guo H, Hsieh D, and Timmins P (2014) Influence of dissolution media pH and USP1 basket speed on erosion and disintegration characteristics of immediate release metformin hydrochloride tablets. Pharm Dev Technol 2014:12 Epub ahead of print.
    • (2014) Pharm Dev Technol , vol.2014 , pp. 12
    • Desai, D.1    Wong, B.2    Huang, Y.3    Tang, D.4    Hemenway, J.5    Paruchuri, S.6    Guo, H.7    Hsieh, D.8    Timmins, P.9
  • 11
    • 84865529593 scopus 로고    scopus 로고
    • The relationship between type 2 diabetes mellitus and failure to proton pump inhibitor treatment in gastroesophageal reflux disease
    • Hershcovici T, Jha LK, Gadam R, Cui H, Gerson L, Thomson S, and Fass R (2012) The relationship between type 2 diabetes mellitus and failure to proton pump inhibitor treatment in gastroesophageal reflux disease. J Clin Gastroenterol 46:662-668.
    • (2012) J Clin Gastroenterol , vol.46 , pp. 662-668
    • Hershcovici, T.1    Jha, L.K.2    Gadam, R.3    Cui, H.4    Gerson, L.5    Thomson, S.6    Fass, R.7
  • 12
    • 84862066298 scopus 로고    scopus 로고
    • Ablation of both organic cation transporter (OCT)1 and OCT2 alters metformin pharmacokinetics but has no effect on tissue drug exposure and pharmacodynamics
    • Higgins JW, Bedwell DW, and Zamek-Gliszczynski MJ (2012) Ablation of both organic cation transporter (OCT)1 and OCT2 alters metformin pharmacokinetics but has no effect on tissue drug exposure and pharmacodynamics. Drug Metab Dispos 40:1170-1177.
    • (2012) Drug Metab Dispos , vol.40 , pp. 1170-1177
    • Higgins, J.W.1    Bedwell, D.W.2    Zamek-Gliszczynski, M.J.3
  • 13
    • 84871614569 scopus 로고    scopus 로고
    • Effects of 12 weeks' treatment with a proton pump inhibitor on insulin secretion, glucose metabolism and markers of cardiovascular risk in patients with type 2 diabetes: A randomised double-blind prospective placebo-controlled study
    • Hove KD, Brøns C, Færch K, Lund SS, Petersen JS, Karlsen AE, Rossing P, Rehfeld JF, and Vaag A (2013) Effects of 12 weeks' treatment with a proton pump inhibitor on insulin secretion, glucose metabolism and markers of cardiovascular risk in patients with type 2 diabetes: a randomised double-blind prospective placebo-controlled study. Diabetologia 56: 22-30.
    • (2013) Diabetologia , vol.56 , pp. 22-30
    • Hove, K.D.1    Brøns, C.2    Færch, K.3    Lund, S.S.4    Petersen, J.S.5    Karlsen, A.E.6    Rossing, P.7    Rehfeld, J.F.8    Vaag, A.9
  • 16
    • 84855995429 scopus 로고    scopus 로고
    • Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney
    • Ito S, Kusuhara H, Yokochi M, Toyoshima J, Inoue K, Yuasa H, and Sugiyama Y (2012) Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney. J Pharmacol Exp Ther 340:393-403.
    • (2012) J Pharmacol Exp Ther , vol.340 , pp. 393-403
    • Ito, S.1    Kusuhara, H.2    Yokochi, M.3    Toyoshima, J.4    Inoue, K.5    Yuasa, H.6    Sugiyama, Y.7
  • 18
    • 79960295006 scopus 로고    scopus 로고
    • Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)
    • Nies AT, Hofmann U, Resch C, Schaeffeler E, Rius M, and Schwab M (2011) Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs). PLoS ONE 6:e22163.
    • (2011) PLoS ONE , vol.6
    • Nies, A.T.1    Hofmann, U.2    Resch, C.3    Schaeffeler, E.4    Rius, M.5    Schwab, M.6
  • 21
    • 0030443768 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus
    • Sambol NC, Chiang J, O'Conner M, Liu CY, Lin ET, Goodman AM, Benet LZ, and Karam JH (1996) Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus. J Clin Pharmacol 36:1012-1021.
    • (1996) J Clin Pharmacol , vol.36 , pp. 1012-1021
    • Sambol, N.C.1    Chiang, J.2    O'Conner, M.3    Liu, C.Y.4    Lin, E.T.5    Goodman, A.M.6    Benet, L.Z.7    Karam, J.H.8
  • 22
    • 33645819547 scopus 로고    scopus 로고
    • Efficacy, tolerability, and safety of a novel once-daily extended-release metformin in patients with type 2 diabetes
    • Schwartz S, Fonseca V, Berner B, Cramer M, Chiang YK, and Lewin A (2006) Efficacy, tolerability, and safety of a novel once-daily extended-release metformin in patients with type 2 diabetes. Diabetes Care 29:759-764.
    • (2006) Diabetes Care , vol.29 , pp. 759-764
    • Schwartz, S.1    Fonseca, V.2    Berner, B.3    Cramer, M.4    Chiang, Y.K.5    Lewin, A.6
  • 23
    • 40449131812 scopus 로고    scopus 로고
    • Therapy Insight: Gastrointestinal complications of diabetes - Pathophysiology and management
    • Sellin JH and Chang EB (2008) Therapy Insight: gastrointestinal complications of diabetes - pathophysiology and management. Nat Clin Pract Gastroenterol Hepatol 5:162-171.
    • (2008) Nat Clin Pract Gastroenterol Hepatol , vol.5 , pp. 162-171
    • Sellin, J.H.1    Chang, E.B.2
  • 26
    • 0033859564 scopus 로고    scopus 로고
    • Review article: Comparison of the pharmacokinetics, acid suppression and efficacy of proton pump inhibitors
    • Stedman CA and Barclay ML (2000) Review article: comparison of the pharmacokinetics, acid suppression and efficacy of proton pump inhibitors. Aliment Pharmacol Ther 14:963-978.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 963-978
    • Stedman, C.A.1    Barclay, M.L.2
  • 27
    • 84873928187 scopus 로고    scopus 로고
    • Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling
    • Wittwer MB, Zur AA, Khuri N, Kido Y, Kosaka A, Zhang X, Morrissey KM, Sali A, Huang Y, and Giacomini KM (2013) Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. J Med Chem 56:781-795.
    • (2013) J Med Chem , vol.56 , pp. 781-795
    • Wittwer, M.B.1    Zur, A.A.2    Khuri, N.3    Kido, Y.4    Kosaka, A.5    Zhang, X.6    Morrissey, K.M.7    Sali, A.8    Huang, Y.9    Giacomini, K.M.10
  • 28
    • 65349128783 scopus 로고    scopus 로고
    • Pharmacokinetic- pharmacodynamic analysis of the role of CYP2C19 genotypes in short-term rabeprazole-based triple therapy against Helicobacter pylori
    • Yang JC, Yang YF, Uang YS, Lin CJ, and Wang TH (2009) Pharmacokinetic- pharmacodynamic analysis of the role of CYP2C19 genotypes in short-term rabeprazole-based triple therapy against Helicobacter pylori. Br J Clin Pharmacol 67:503-510.
    • (2009) Br J Clin Pharmacol , vol.67 , pp. 503-510
    • Yang, J.C.1    Yang, Y.F.2    Uang, Y.S.3    Lin, C.J.4    Wang, T.H.5
  • 29
    • 34748922537 scopus 로고    scopus 로고
    • Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine
    • Zhou M, Xia L, and Wang J (2007) Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine. Drug Metab Dispos 35:1956-1962.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1956-1962
    • Zhou, M.1    Xia, L.2    Wang, J.3


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