Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 7, 2014, Pages 1446-1458

  Nave, Alexander H ^a,b,d   Mižíková, Ivana ^a,b   Niess, Gero ^a,b   Steenbock, Heiko ^c   Reichenberger, Frank ^a,e   Talavera, María L ^a,f   Veit, Florian ^a   Herold, Susanne ^a   Mayer, Konstantin ^a   Vadász, István ^a   Weissmann, Norbert ^a   Seeger, Werner ^a,b   Brinckmann, Jürgen ^c   Morty, Rory E ^a,b  

^a JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^c UNIVERSITY OF LÜBECK   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e Asklepios Lung Centre   (Germany)

^f HOSPITAL UNIVERSITARIO FUNDACIÓN FAVALORO   (Argentina)

Author keywords

anoxia; extracellular matrix; hypertension; muscle; protein lysine 6 oxidase; pulmonary; smooth

Indexed keywords

3 AMINOPROPIONITRILE; COLLAGEN; DIHYDROXYLYSINONORLEUCIN; HYDROXYLYSINONORLEUCINE; LYSYL OXIDASE L1; LYSYL OXIDASE L2; LYSYL OXIDASE L3; LYSYL OXIDASE L4; PROTEIN LYSINE 6 OXIDASE; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST; HEART RIGHT VENTRICLE HYPERTROPHY; HUMAN; HUMAN TISSUE; HYPOXIA; LUNG; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER; SYSTOLIC BLOOD PRESSURE; VASCULAR LESION;

ANOXIA; EXTRACELLULAR MATRIX; HYPERTENSION; MUSCLE; PROTEIN-LYSINE 6-OXIDASE; PULMONARY; SMOOTH;

ADULT; AGED, 80 AND OVER; ANIMALS; ANOXIA; ANTIHYPERTENSIVE AGENTS; CASE-CONTROL STUDIES; CELL HYPOXIA; CELLS, CULTURED; COLLAGEN; DISEASE MODELS, ANIMAL; ELASTIN; ENZYME INHIBITORS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; ISOENZYMES; MALE; MICE; MIDDLE AGED; MONOCROTALINE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN-LYSINE 6-OXIDASE; PULMONARY ARTERY; RATS; RNA, MESSENGER; VENTRICULAR DYSFUNCTION, RIGHT; YOUNG ADULT;

EID: 84903128936     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303534     Document Type: Article

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