The metabolic enhancer piracetam attenuates mitochondrion-specific endonuclease G translocation and oxidative DNA fragmentation

Free Radical Biology and Medicine

Volumn 73, Issue , 2014, Pages 278-290

  Gupta, Sonam ^a   Verma, Dinesh Kumar ^a   Biswas, Joyshree ^a   Siva Rama Raju, K ^a   Joshi, Neeraj ^b   Wahajuddin, ^a   Singh, Sarika ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

Astrocytes; DNA damage; Endonuclease G; Free radicals; Lipopolysaccharide; Piracetam

Indexed keywords

BETA ACTIN; CASPASE 3; ENDONUCLEASE G; LIPOPOLYSACCHARIDE; MESSENGER RNA; OXIDOREDUCTASE; PIRACETAM; DEOXYRIBONUCLEASE; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; ASTROCYTE; ATTENUATION; CELL ACTIVITY; CELL STRUCTURE; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; CULTURE MEDIUM; DNA DAMAGE; DNA FRAGMENTATION; DRUG ABSORPTION; DRUG CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVITY; GLIA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM;

ANIMALS; APOPTOSIS; ASTROCYTES; CASPASE 3; CELL LINE; CELL SURVIVAL; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA FRAGMENTATION; ENDODEOXYRIBONUCLEASES; LIPOPOLYSACCHARIDES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; OXIDOREDUCTASES; PIRACETAM; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 84903128515     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.05.014     Document Type: Article

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