-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
84878737559
-
Report of incidence and mortality in China cancer registries, 2009
-
Chen W, Zheng R, Zhang S, Zhao P, Li G, Wu L, et al. Report of incidence and mortality in China cancer registries, 2009. Chin J Cancer Res. 2013;25:10-21.
-
(2013)
Chin J Cancer Res
, vol.25
, pp. 10-21
-
-
Chen, W.1
Zheng, R.2
Zhang, S.3
Zhao, P.4
Li, G.5
Wu, L.6
-
3
-
-
0030730907
-
Associations of sedentary lifestyle, obesity, smoking, alcohol use, and diabetes with the risk of colorectal cancer
-
Le Marchand L, Wilkens LR, Kolonel LN, Hankin JH, Lyu LC. Associations of sedentary lifestyle, obesity, smoking, alcohol use, and diabetes with the risk of colorectal cancer. Cancer Res. 1997;57:4787-94. (Pubitemid 27468985)
-
(1997)
Cancer Research
, vol.57
, Issue.21
, pp. 4787-4794
-
-
Le, M.L.1
Wilkens, L.R.2
Kolonel, L.N.3
Hankin, J.H.4
Lyu, L.-C.5
-
4
-
-
48549083915
-
Cigarette smoking and colorectal cancer risk: A burning issue
-
Limsui D, Limburg PJ. Cigarette smoking and colorectal cancer risk: a burning issue. Gastroenterology. 2008;135:704-5.
-
(2008)
Gastroenterology
, vol.135
, pp. 704-705
-
-
Limsui, D.1
Limburg, P.J.2
-
5
-
-
84876739380
-
Nqo1 609C>T polymorphism interaction with tobacco smoking and alcohol drinking increases colorectal cancer risk in a Chinese population
-
Peng XE, Jiang YY, Shi XS, Hu ZJ. Nqo1 609C>T polymorphism interaction with tobacco smoking and alcohol drinking increases colorectal cancer risk in a Chinese population. Gene. 2013;521:105-10.
-
(2013)
Gene
, vol.521
, pp. 105-110
-
-
Peng, X.E.1
Jiang, Y.Y.2
Shi, X.S.3
Hu, Z.J.4
-
6
-
-
84875944427
-
Genetic variations in the tgfbeta signaling pathway, smoking and risk of colorectal cancer in a chinese population
-
Zhong R, Liu L, Zou L, Sheng W, Zhu B, Xiang H, et al. Genetic variations in the tgfbeta signaling pathway, smoking and risk of colorectal cancer in a chinese population. Carcinogenesis. 2013;34:936-42.
-
(2013)
Carcinogenesis
, vol.34
, pp. 936-942
-
-
Zhong, R.1
Liu, L.2
Zou, L.3
Sheng, W.4
Zhu, B.5
Xiang, H.6
-
7
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer: Analyses of cohorts of twins from Sweden, Denmark, and Finland
-
DOI 10.1056/NEJM200007133430201
-
Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M, et al. Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland. New Engl J Med. 2000;343:78-85. (Pubitemid 30451850)
-
(2000)
New England Journal of Medicine
, vol.343
, Issue.2
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
Iliadou, A.4
Kaprio, J.5
Koskenvuo, M.6
Pukkala, E.7
Skytthe, A.8
Hemminki, K.9
-
8
-
-
67349245787
-
New insights into the aetiology of colorectal cancer from genome-wide association studies
-
Tenesa A, Dunlop MG. New insights into the aetiology of colorectal cancer from genome-wide association studies. Nature Rev Genet. 2009;10:353-8.
-
(2009)
Nature Rev Genet
, vol.10
, pp. 353-358
-
-
Tenesa, A.1
Dunlop, M.G.2
-
9
-
-
84860992315
-
Cyclin d1 g870a polymorphism contributes to colorectal cancer susceptibility: Evidence from a systematic review of 22 case-control studies
-
Yang Y, Wang F, Shi C, Zou Y, Qin H, Ma Y. Cyclin d1 g870a polymorphism contributes to colorectal cancer susceptibility: evidence from a systematic review of 22 case-control studies. PloS One. 2012;7:e36813.
-
(2012)
PloS One
, vol.7
-
-
Yang, Y.1
Wang, F.2
Shi, C.3
Zou, Y.4
Qin, H.5
Ma, Y.6
-
10
-
-
84860473474
-
An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients
-
Crea F, Fornaro L, Paolicchi E, Masi G, Frumento P, Loupakis F, et al. An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients. Annals Oncol. 2012;23:1207-13.
-
(2012)
Annals Oncol
, vol.23
, pp. 1207-1213
-
-
Crea, F.1
Fornaro, L.2
Paolicchi, E.3
Masi, G.4
Frumento, P.5
Loupakis, F.6
-
11
-
-
79955531832
-
Tlr-3 polymorphism is an independent prognostic marker for stage II colorectal cancer
-
Castro FA, Forsti A, Buch S, Kalthoff H, Krauss C, Bauer M, et al. Tlr-3 polymorphism is an independent prognostic marker for stage II colorectal cancer. Eur J Cancer. 2011;47:1203-10.
-
(2011)
Eur J Cancer
, vol.47
, pp. 1203-1210
-
-
Castro, F.A.1
Forsti, A.2
Buch, S.3
Kalthoff, H.4
Krauss, C.5
Bauer, M.6
-
12
-
-
56749176944
-
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
-
Houlston RS, Webb E, Broderick P, Pittman AM, Di Bernardo MC, Lubbe S, et al. Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nature Genet. 2008;40:1426-35.
-
(2008)
Nature Genet
, vol.40
, pp. 1426-1435
-
-
Houlston, R.S.1
Webb, E.2
Broderick, P.3
Pittman, A.M.4
Di Bernardo, M.C.5
Lubbe, S.6
-
13
-
-
3543037590
-
TGFbeta signaling in health and disease
-
DOI 10.1038/ng0804-790
-
Akhurst RJ. TGF beta signaling in health and disease. Nature Genet. 2004;36:790-2. (Pubitemid 39014092)
-
(2004)
Nature Genetics
, vol.36
, Issue.8
, pp. 790-792
-
-
Akhurst, R.J.1
-
14
-
-
15744372725
-
Role of transforming growth factor beta in human cancer
-
DOI 10.1200/JCO.2005.02.047
-
Elliott RL, Blobe GC. Role of transforming growth factor beta in human cancer. J Clin Oncol. 2005;23:2078-93. (Pubitemid 46211385)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.9
, pp. 2078-2093
-
-
Elliott, R.L.1
Blobe, G.C.2
-
16
-
-
33745515023
-
Tumour microenvironment - TGFbeta: The molecular Jekyll and Hyde of cancer
-
DOI 10.1038/nrc1926, PII N1926
-
Bierie B, Moses HL. Tumour microenvironment: TGF beta: the molecular Jekyll and Hyde of cancer. Nature Rev Cancer. 2006;6:506-20. (Pubitemid 43980540)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.7
, pp. 506-520
-
-
Bierie, B.1
Moses, H.L.2
-
17
-
-
33846894808
-
Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: A novel mutation in SMAD3 associated with the inactivation of TGF-beta-induced transcriptional activation
-
Ku JL, Park SH, Yoon KA, Shin YK, Kim KH, Choi JS, et al.Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: a novel mutation in SMAD3 associated with the inactivation of TGF-beta-induced transcriptional activation. Cancer Lett. 2007;247:283-92.
-
(2007)
Cancer Lett
, vol.247
, pp. 283-292
-
-
Ku, J.L.1
Park, S.H.2
Yoon, K.A.3
Shin, Y.K.4
Kim, K.H.5
Choi, J.S.6
-
18
-
-
34547789841
-
TGF-beta signaling alterations and susceptibility to colorectal cancer
-
DOI 10.1093/hmg/ddl486, Cancer Genetics
-
Xu Y, Pasche B. Tgf-beta signaling alterations and susceptibility to colorectal cancer. Human molecular genetics 2007;16 Spec No 1:R14-20 (Pubitemid 47241839)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.R1
-
-
Xu, Y.1
Pasche, B.2
-
19
-
-
0037700139
-
Mutational analysis of TGF-beta type II receptor, Smad2, Smad3, Smad4, Smad6 and Smad7 genes in colorectal cancer
-
Fukushima T, Mashiko M, Takita K, Otake T, Endo Y, Sekikawa K, et al. Mutational analysis of tgf-beta type ii receptor, smad2, smad3, smad4, smad6 and smad7 genes in colorectal cancer. J Exp Clin Cancer Res. 2003;22:315-20. (Pubitemid 36734191)
-
(2003)
Journal of Experimental and Clinical Cancer Research
, vol.22
, Issue.2
, pp. 315-320
-
-
Fukushima, T.1
Mashiko, M.2
Takita, K.3
Otake, T.4
Endo, Y.5
Sekikawa, K.6
Takenoshita, S.7
-
20
-
-
0347444723
-
MicrorNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicrorNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-97.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
21
-
-
58249088751
-
MicrorNAs: Target recognition and regulatory functions
-
Bartel DP. MicrorNAs: target recognition and regulatory functions. Cell. 2009;136:215-33.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
22
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120:15-20. (Pubitemid 40094598)
-
(2005)
Cell
, vol.120
, Issue.1
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
23
-
-
40749145370
-
Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein
-
Wang G, van der Walt JM, Mayhew G, Li YJ, Zuchner S, Scott WK, et al. Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. Am J Human Genet. 2008;82:283-9.
-
(2008)
Am J Human Genet
, vol.82
, pp. 283-289
-
-
Wang, G.1
Van Der Walt, J.M.2
Mayhew, G.3
Li, Y.J.4
Zuchner, S.5
Scott, W.K.6
-
24
-
-
84055212034
-
A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer
-
Smits KM, Paranjape T, Nallur S, Wouters KA, Weijenberg MP, Schouten LJ, et al. A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer. Clinical Cancer Res. 2011;17:7723-31.
-
(2011)
Clinical Cancer Res
, vol.17
, pp. 7723-7731
-
-
Smits, K.M.1
Paranjape, T.2
Nallur, S.3
Wouters, K.A.4
Weijenberg, M.P.5
Schouten, L.J.6
-
25
-
-
34547727263
-
Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: A mechanism for functional single-nucleotide polymorphisms related to phenotypes
-
DOI 10.1086/519979
-
Sethupathy P, Borel C, Gagnebin M, Grant GR, Deutsch S, Elton TS, et al. Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes. Am J Human Genet. 2007;81:405-13. (Pubitemid 47236088)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.2
, pp. 405-413
-
-
Sethupathy, P.1
Borel, C.2
Gagnebin, M.3
Grant, G.R.4
Deutsch, S.5
Elton, T.S.6
Hatzigeorgiou, A.G.7
Antonarakis, S.E.8
-
26
-
-
84857691987
-
Genomewide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis
-
Gong J, Tong Y, Zhang HM, Wang K, Hu T, Shan G, et al. Genomewide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis. Hum Mutat. 2012;33:254-63.
-
(2012)
Hum Mutat
, vol.33
, pp. 254-263
-
-
Gong, J.1
Tong, Y.2
Zhang, H.M.3
Wang, K.4
Hu, T.5
Shan, G.6
-
27
-
-
35848948207
-
Activin receptor-like kinase-2 inhibits activin signaling by blocking the binding of activin to its type II receptor
-
DOI 10.1677/JOE-07-0281
-
Renlund N, O'Neill FH, Zhang L, Sidis Y, Teixeira J. Activin receptor-like kinase-2 inhibits activin signaling by blocking the binding of activin to its type II receptor. J Endocrinol. 2007;195:95-103. (Pubitemid 350056003)
-
(2007)
Journal of Endocrinology
, vol.195
, Issue.1
, pp. 95-103
-
-
Renlund, N.1
O'Neill, F.H.2
Zhang, L.H.3
Sidis, Y.4
Teixeira, J.5
-
28
-
-
0028260297
-
Expression of activin receptor II and IIB mRNA isoforms in mouse reproductive organs and oocytes
-
Wu TC, Jih MH, Wang L, Wan YJ. Expression of activin receptor II and IIB mRNA isoforms in mouse reproductive organs and oocytes. Mol Reprod Dev. 1994;38:9-15. (Pubitemid 24139851)
-
(1994)
Molecular Reproduction and Development
, vol.38
, Issue.1
, pp. 9-15
-
-
Wu, T.-C.J.1
Jih, M.H.2
Wang, L.3
Wan, Y.Y.4
-
29
-
-
0026634783
-
Molecular cloning and binding properties of the human type II activin receptor
-
Donaldson CJ, Mathews LS, Vale WW. Molecular cloning and binding properties of the human type II activin receptor. Biochem Biophys Res Comm. 1992;184:310-6.
-
(1992)
Biochem Biophys Res Comm
, vol.184
, pp. 310-316
-
-
Donaldson, C.J.1
Mathews, L.S.2
Vale, W.W.3
-
30
-
-
84872485722
-
Acvr1 Gene mutations in four Turkish patients diagnosed as fibrodysplasia ossificans progressiva
-
Eresen Yazicioglu C, Karatosun V, Kizildag S, Ozsoylu D, Kavukcu S. Acvr1 Gene mutations in four Turkish patients diagnosed as fibrodysplasia ossificans progressiva. Gene. 2013;515:444-6.
-
(2013)
Gene
, vol.515
, pp. 444-446
-
-
Eresen Yazicioglu, C.1
Karatosun, V.2
Kizildag, S.3
Ozsoylu, D.4
Kavukcu, S.5
-
31
-
-
33646348736
-
A recurrent mutation in the bmp type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
-
Shore EM, Xu M, Feldman GJ, Fenstermacher DA, Cho TJ, Choi IH, et al. A recurrent mutation in the bmp type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nature Genet. 2006;38:525-7.
-
(2006)
Nature Genet
, vol.38
, pp. 525-527
-
-
Shore, E.M.1
Xu, M.2
Feldman, G.J.3
Fenstermacher, D.A.4
Cho, T.J.5
Choi, I.H.6
-
32
-
-
79960462297
-
Recurrent copy number gains of ACVR1 and corresponding transcript overexpression are associated with survival in head and neck squamous cell carcinomas
-
Ambrosio EP, Drigo SA, Bergamo NA, Rosa FE, Bertonha FB, de Abreu FB, et al. Recurrent copy number gains of ACVR1 and corresponding transcript overexpression are associated with survival in head and neck squamous cell carcinomas. Histopathology. 2011;59:81-9.
-
(2011)
Histopathology
, vol.59
, pp. 81-89
-
-
Ambrosio, E.P.1
Drigo, S.A.2
Bergamo, N.A.3
Rosa, F.E.4
Bertonha, F.B.5
De Abreu, F.B.6
-
33
-
-
79959680172
-
The tumor suppressor gene TRP53 protects themouse lens against posterior subcapsular cataracts and the bmp receptor ACVR1 acts as a tumor suppressor in the lens
-
Wiley LA, Rajagopal R, Dattilo LK, Beebe DC. The tumor suppressor gene TRP53 protects themouse lens against posterior subcapsular cataracts and the bmp receptor ACVR1 acts as a tumor suppressor in the lens. Disease Models Mech. 2011;4:484-95.
-
(2011)
Disease Models Mech
, vol.4
, pp. 484-495
-
-
Wiley, L.A.1
Rajagopal, R.2
Dattilo, L.K.3
Beebe, D.C.4
-
34
-
-
77950822671
-
Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility
-
Nicoloso MS, Sun H, Spizzo R, Kim H, Wickramasinghe P, Shimizu M, et al. Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res. 2010;70:2789-98.
-
(2010)
Cancer Res
, vol.70
, pp. 2789-2798
-
-
Nicoloso, M.S.1
Sun, H.2
Spizzo, R.3
Kim, H.4
Wickramasinghe, P.5
Shimizu, M.6
-
35
-
-
84875462661
-
Single-nucleotide polymorphisms inside microrna target sites influence the susceptibility to type 2 diabetes
-
Zhao X, Ye Q, Xu K, Cheng J, Gao Y, Li Q, et al. Single-nucleotide polymorphisms inside microrna target sites influence the susceptibility to type 2 diabetes. J Human Genet. 2013;58:135-41.
-
(2013)
J Human Genet
, vol.58
, pp. 135-141
-
-
Zhao, X.1
Ye, Q.2
Xu, K.3
Cheng, J.4
Gao, Y.5
Li, Q.6
|