SCOPUS 정보 검색 플랫폼

Biochemical and Biophysical Research Communications

Volumn 449, Issue 4, 2014, Pages 373-376

Molecular control of mitochondrial calcium uptake

(2) De Stefani, Diego a Rizzuto, Rosario a

a UNIVERSITY OF PADOVA (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CARRIER PROTEIN; MITOCHONDRIAL CALCIUM UNIPORTER; MULTIPROTEIN COMPLEX; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; CALCIUM BINDING; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONFORMATIONAL TRANSITION; HEART MITOCHONDRION; HUMAN; MITOCHONDRION; MUSCLE MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; REVIEW; SKELETAL MUSCLE; STRUCTURE ACTIVITY RELATION;

CALCIUM CHANNELS; CALCIUM SIGNALING; HUMANS; LIPID BILAYERS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES;

EID: 84902840349 PISSN: 0006291X EISSN: 10902104 Source Type: Journal
DOI: 10.1016/j.bbrc.2014.04.142 Document Type: Note

Times cited : (24)

References (29)

1
- 80051936634
- A forty-Kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- D. De Stefani, A. Raffaello, E. Teardo, I. Szabo, R. Rizzuto, A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter, Nature 476 (2011) 336-340.
- (2011) Nature , vol.476 , pp. 336-340
- De Stefani, D.¹ Raffaello, A.² Teardo, E.³ Szabo, I.⁴ Rizzuto, R.⁵

2
- 80051946060
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- J.M. Baughman, F. Perocchi, H.S. Girgis, M. Plovanich, C.A. Belcher-Timme, Y. Sancak, X.R. Bao, L. Strittmatter, O. Goldberger, R.L. Bogorad, V. Koteliansky, V.K. Mootha, Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter, Nature 476 (2011) 341-345.
- (2011) Nature , vol.476 , pp. 341-345
- Baughman, J.M.¹ Perocchi, F.² Girgis, H.S.³ Plovanich, M.⁴ Belcher-Timme, C.A.⁵ Sancak, Y.⁶ Bao, X.R.⁷ Strittmatter, L.⁸ Goldberger, O.⁹ Bogorad, R.L.¹⁰ Koteliansky, V.¹¹ Mootha, V.K.¹²

3
- 84865427488
- Mitochondria as sensors and regulators of calcium signalling
- R. Rizzuto, D. De Stefani, A. Raffaello, C. Mammucari, Mitochondria as sensors and regulators of calcium signalling, Nat. Rev. Mol. Cell. Biol. 13 (2012) 566-578.
- (2012) Nat. Rev. Mol. Cell. Biol. , vol.13 , pp. 566-578
- Rizzuto, R.¹ De Stefani, D.² Raffaello, A.³ Mammucari, C.⁴

4
- 84883286784
- The mitochondrial calcium uniporter is a multimer that can include a dominant-Negative pore-Forming subunit
- A. Raffaello, D. De Stefani, D. Sabbadin, E. Teardo, G. Merli, A. Picard, V. Checchetto, S. Moro, I. Szabo, R. Rizzuto, The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit, EMBO J. 32 (2013) 2362-2376.
- (2013) EMBO J , vol.32 , pp. 2362-2376
- Raffaello, A.¹ De Stefani, D.² Sabbadin, D.³ Teardo, E.⁴ Merli, G.⁵ Picard, A.⁶ Checchetto, V.⁷ Moro, S.⁸ Szabo, I.⁹ Rizzuto, R.¹⁰

5
- 77956928316
- MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake
- F. Perocchi, V.M. Gohil, H.S. Girgis, X.R. Bao, J.E. McCombs, A.E. Palmer, V.K. Mootha, MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake, Nature 467 (2010) 291-296.
- (2010) Nature , vol.467 , pp. 291-296
- Perocchi, F.¹ Gohil, V.M.² Girgis, H.S.³ Bao, X.R.⁴ McCombs, J.E.⁵ Palmer, A.E.⁶ Mootha, V.K.⁷

6
- 84870621600
- MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism
- K. Mallilankaraman, C. Cardenas, P.J. Doonan, H.C. Chandramoorthy, K.M. Irrinki, T. Golenar, G. Csordas, P. Madireddi, J. Yang, M. Muller, R. Miller, J.E. Kolesar, J. Molgo, B. Kaufman, G. Hajnoczky, J.K. Foskett, M. Madesh, MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism, Nat. Cell Biol. 14 (2012) 1336-1343.
- (2012) Nat. Cell Biol. , vol.14 , pp. 1336-1343
- Mallilankaraman, K.¹ Cardenas, C.² Doonan, P.J.³ Chandramoorthy, H.C.⁴ Irrinki, K.M.⁵ Golenar, T.⁶ Csordas, G.⁷ Madireddi, P.⁸ Yang, J.⁹ Muller, M.¹⁰ Miller, R.¹¹ Kolesar, J.E.¹² Molgo, J.¹³ Kaufman, B.¹⁴ Hajnoczky, G.¹⁵ Foskett, J.K.¹⁶ Madesh, M.¹⁷

7
- 84873572862
- MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling
- M. Plovanich, R.L. Bogorad, Y. Sancak, K.J. Kamer, L. Strittmatter, A.A. Li, H.S. Girgis, S. Kuchimanchi, J. De Groot, L. Speciner, N. Taneja, J. Oshea, V. Koteliansky, V.K. Mootha, MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling, PLoS One 8 (2013) e55785.
- (2013) PLoS One , vol.8
- Plovanich, M.¹ Bogorad, R.L.² Sancak, Y.³ Kamer, K.J.⁴ Strittmatter, L.⁵ Li, A.A.⁶ Girgis, H.S.⁷ Kuchimanchi, S.⁸ De Groot, J.⁹ Speciner, L.¹⁰ Taneja, N.¹¹ Oshea, J.¹² Koteliansky, V.¹³ Mootha, V.K.¹⁴

8
- 84890116192
- EMRE is an essential component of the mitochondrial calcium uniporter complex
- Y. Sancak, A.L. Markhard, T. Kitami, E. Kovacs-Bogdan, K.J. Kamer, N.D. Udeshi, S.A. Carr, D. Chaudhuri, D.E. Clapham, A.A. Li, S.E. Calvo, O. Goldberger, V.K. Mootha, EMRE is an essential component of the mitochondrial calcium uniporter complex, Science 342 (2013) 1379-1382.
- (2013) Science , vol.342 , pp. 1379-1382
- Sancak, Y.¹ Markhard, A.L.² Kitami, T.³ Kovacs-Bogdan, E.⁴ Kamer, K.J.⁵ Udeshi, N.D.⁶ Carr, S.A.⁷ Chaudhuri, D.⁸ Clapham, D.E.⁹ Li, A.A.¹⁰ Calvo, S.E.¹¹ Goldberger, O.¹² Mootha, V.K.¹³

9
- 84896262743
- 2+ uptake, interacts with MCU, and induces oxidative stress-Mediated cell death
- 2+ uptake, interacts with MCU, and induces oxidative stress-mediated cell death, Mol. Biol. Cell 25 (2014) 936-947.
- (2014) Mol. Biol. Cell , vol.25 , pp. 936-947
- Hoffman, N.E.¹ Chandramoorthy, H.C.² Shanmughapriya, S.³ Zhang, X.Q.⁴ Vallem, S.⁵ Doonan, P.J.⁶ Malliankaraman, K.⁷ Guo, S.⁸ Rajan, S.⁹ Elrod, J.W.¹⁰ Koch, W.J.¹¹ Cheung, J.Y.¹² Madesh, M.¹³

10
- 84864645903
- 2+ peaks in cardiomyocytes
- 2+ peaks in cardiomyocytes, Proc. Natl. Acad. Sci. U.S.A. 109 (2012) 12986-12991.
- (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 12986-12991
- Drago, I.¹ De Stefani, D.² Rizzuto, R.³ Pozzan, T.⁴

11
- 84868629814
- CaMKII determines mitochondrial stress responses in heart
- M.L. Joiner, O.M. Koval, J. Li, B.J. He, C. Allamargot, Z. Gao, E.D. Luczak, D.D. Hall, B.D. Fink, B. Chen, J. Yang, S.A. Moore, T.D. Scholz, S. Strack, P.J. Mohler, W.I. Sivitz, L.S. Song, M.E. Anderson, CaMKII determines mitochondrial stress responses in heart, Nature 491 (2012) 269-273.
- (2012) Nature , vol.491 , pp. 269-273
- Joiner, M.L.¹ Koval, O.M.² Li, J.³ He, B.J.⁴ Allamargot, C.⁵ Gao, Z.⁶ Luczak, E.D.⁷ Hall, D.D.⁸ Fink, B.D.⁹ Chen, B.¹⁰ Yang, J.¹¹ Moore, S.A.¹² Scholz, T.D.¹³ Strack, S.¹⁴ Mohler, P.J.¹⁵ Sivitz, W.I.¹⁶ Song, L.S.¹⁷ Anderson, M.E.¹⁸

12
- 84864070892
- 2+ uniporter MCU is essential for glucose-Induced ATP increases in pancreatic beta-cells
- 2+ uniporter MCU is essential for glucose-induced ATP increases in pancreatic beta-cells, PLoS One 7 (2012) e39722.
- (2012) PLoS One , vol.7
- Tarasov, A.I.¹ Semplici, F.² Ravier, M.A.³ Bellomo, E.A.⁴ Pullen, T.J.⁵ Gilon, P.⁶ Sekler, I.⁷ Rizzuto, R.⁸ Rutter, G.A.⁹

13
- 84867272349
- 2+ uniporter (MCU) contribute to metabolismsecretion coupling in clonal pancreatic beta-Cells
- 2+ uniporter (MCU) contribute to metabolismsecretion coupling in clonal pancreatic beta-cells, J. Biol. Chem. 287 (2012) 34445-34454.
- (2012) J. Biol. Chem. , vol.287 , pp. 34445-34454
- Alam, M.R.¹ Groschner, L.N.² Parichatikanond, W.³ Kuo, L.⁴ Bondarenko, A.I.⁵ Rost, R.⁶ Waldeck-Weiermair, M.⁷ Malli, R.⁸ Graier, W.F.⁹

14
- 84872117185
- Downregulation of the mitochondrial calcium uniporter by cancer-Related miR-25
- S. Marchi, L. Lupini, S. Patergnani, A. Rimessi, S. Missiroli, M. Bonora, A. Bononi, F. Corra, C. Giorgi, E. De Marchi, F. Poletti, R. Gafa, G. Lanza, M. Negrini, R. Rizzuto, P. Pinton, Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25, Curr. Biol. 23 (2013) 58-63.
- (2013) Curr. Biol. , vol.23 , pp. 58-63
- Marchi, S.¹ Lupini, L.² Patergnani, S.³ Rimessi, A.⁴ Missiroli, S.⁵ Bonora, M.⁶ Bononi, A.⁷ Corra, F.⁸ Giorgi, C.⁹ De Marchi, E.¹⁰ Poletti, F.¹¹ Gafa, R.¹² Lanza, G.¹³ Negrini, M.¹⁴ Rizzuto, R.¹⁵ Pinton, P.¹⁶

15
- 84880471564
- Mitochondrial calcium uniporter silencing potentiates caspase-Independent cell death in MDA-MB-231 breast cancer cells
- M.C. Curry, A.A. Peters, P.A. Kenny, S.J. Roberts-Thomson, G.R. Monteith, Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells, Biochem. Biophys. Res. Commun. 434 (2013) 695-700.
- (2013) Biochem. Biophys. Res. Commun. , vol.434 , pp. 695-700
- Curry, M.C.¹ Peters, A.A.² Kenny, P.A.³ Roberts-Thomson, S.J.⁴ Monteith, G.R.⁵

16
- 84879627185
- Mitochondrial calcium uniporter mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals
- J. Qiu, Y.W. Tan, A.M. Hagenston, M.A. Martel, N. Kneisel, P.A. Skehel, D.J. Wyllie, H. Bading, G.E. Hardingham, Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals, Nat. Commun. 4 (2013) 2034.
- (2013) Nat. Commun. , vol.4 , pp. 2034
- Qiu, J.¹ Tan, Y.W.² Hagenston, A.M.³ Martel, M.A.⁴ Kneisel, N.⁵ Skehel, P.A.⁶ Wyllie, D.J.⁷ Bading, H.⁸ Hardingham, G.E.⁹

17
- 84891393224
- The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
- X. Pan, J. Liu, T. Nguyen, C. Liu, J. Sun, Y. Teng, I.I. Rovira, M. Allen, D.A. Springer, A.M. Aponte, M. Gucek, M.M. Fergusson, R.S. Balaban, E. Murphy, T. Finkel, The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter, Nat. Cell Biol. 15 (2013) 1464-1472.
- (2013) Nat. Cell Biol. , vol.15 , pp. 1464-1472
- Pan, X.¹ Liu, J.² Nguyen, T.³ Liu, C.⁴ Sun, J.⁵ Teng, Y.⁶ Rovira, I.I.⁷ Allen, M.⁸ Springer, D.A.⁹ Aponte, A.M.¹⁰ Gucek, M.¹¹ Fergusson, M.M.¹² Balaban, R.S.¹³ Murphy, E.¹⁴ Finkel, T.¹⁵

18
- 84890104070
- Essential regulation of cell bioenergetics in trypanosoma brucei by the mitochondrial calcium uniporter
- G. Huang, A.E. Vercesi, R. Docampo, Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter, Nat. Commun. 4 (2013) 2865.
- (2013) Nat. Commun. , vol.4 , pp. 2865
- Huang, G.¹ Vercesi, A.E.² Docampo, R.³

19
- 84892913623
- 2+ uptake in MICU1-knockdown cells
- 2+ uptake in MICU1-knockdown cells, Biochem. J. 458 (2014) 33-40.
- (2014) Biochem. J. , vol.458 , pp. 33-40
- De La Fuente, S.¹ Matesanz-Isabel, J.² Fonteriz, R.I.³ Montero, M.⁴ Alvarez, J.⁵

20
- 84896703008
- MICU1 and MICU2 finely tune the mitochondrial Ca(2+) uniporter by exerting opposite effects on MCU activity
- M. Patron, V. Checchetto, A. Raffaello, E. Teardo, D. Vecellio Reane, M. Mantoan, V. Granatiero, I. Szabo, D. De Stefani, R. Rizzuto, MICU1 and MICU2 finely tune the mitochondrial Ca(2+) uniporter by exerting opposite effects on MCU activity, Mol. Cell 53 (2014) 726-737.
- (2014) Mol. Cell , vol.53 , pp. 726-737
- Patron, M.¹ Checchetto, V.² Raffaello, A.³ Teardo, E.⁴ Vecellio Reane, D.⁵ Mantoan, M.⁶ Granatiero, V.⁷ Szabo, I.⁸ De Stefani, D.⁹ Rizzuto, R.¹⁰

21
- 84878796986
- MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca(2)(+) uniporter
- G. Csordas, T. Golenar, E.L. Seifert, K.J. Kamer, Y. Sancak, F. Perocchi, C. Moffat, D. Weaver, S. de la Fuente Perez, R. Bogorad, V. Koteliansky, J. Adijanto, V.K. Mootha, G. Hajnoczky, MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca(2)(+) uniporter, Cell Metab. 17 (2013) 976- 987.
- (2013) Cell Metab , vol.17 , pp. 976-987
- Csordas, G.¹ Golenar, T.² Seifert, E.L.³ Kamer, K.J.⁴ Sancak, Y.⁵ Perocchi, F.⁶ Moffat, C.⁷ Weaver, D.⁸ De La Fuente, P.S.⁹ Bogorad, R.¹⁰ Koteliansky, V.¹¹ Adijanto, J.¹² Mootha, V.K.¹³ Hajnoczky, G.¹⁴

22
- 84868027665
- MICU1 is an essential gatekeeper for MCU-Mediated mitochondrial Ca(2+) uptake that regulates cell survival
- K. Mallilankaraman, P. Doonan, C. Cardenas, H.C. Chandramoorthy, M. Muller, R. Miller, N.E. Hoffman, R.K. Gandhirajan, J. Molgo, M.J. Birnbaum, B.S. Rothberg, D.O. Mak, J.K. Foskett, M. Madesh, MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival, Cell 151 (2012) 630-644.
- (2012) Cell , vol.151 , pp. 630-644
- Mallilankaraman, K.¹ Doonan, P.² Cardenas, C.³ Chandramoorthy, H.C.⁴ Muller, M.⁵ Miller, R.⁶ Hoffman, N.E.⁷ Gandhirajan, R.K.⁸ Molgo, J.⁹ Birnbaum, M.J.¹⁰ Rothberg, B.S.¹¹ Mak, D.O.¹² Foskett, J.K.¹³ Madesh, M.¹⁴

23
- 1642540210
- The mitochondrial calcium uniporter is a highly selective ion channel
- DOI 10.1038/nature02246
- Y. Kirichok, G. Krapivinsky, D.E. Clapham, The mitochondrial calcium uniporter is a highly selective ion channel, Nature 427 (2004) 360-364. (Pubitemid 38133664)
- (2004) Nature , vol.427 , Issue.6972 , pp. 360-364
- Kirichok, Y.¹ Krapivinsky, G.² Clapham, D.E.³

24
- 66549102938
- 2+ channels
- 2+ channels, Circulation 119 (2009) 2435-2443.
- (2009) Circulation , vol.119 , pp. 2435-2443
- Michels, G.¹ Khan, I.F.² Endres-Becker, J.³ Rottlaender, D.⁴ Herzig, S.⁵ Ruhparwar, A.⁶ Wahlers, T.⁷ Hoppe, U.C.⁸

25
- 84871891066
- Activity of the mitochondrial calcium uniporter varies greatly between tissues
- F. Fieni, S.B. Lee, Y.N. Jan, Y. Kirichok, Activity of the mitochondrial calcium uniporter varies greatly between tissues, Nat. Commun. 3 (2012) 1317.
- (2012) Nat. Commun. , vol.3 , pp. 1317
- Fieni, F.¹ Lee, S.B.² Jan, Y.N.³ Kirichok, Y.⁴

26
- 84869458315
- Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
- J.D. Martell, T.J. Deerinck, Y. Sancak, T.L. Poulos, V.K. Mootha, G.E. Sosinsky, M.H. Ellisman, A.Y. Ting, Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy, Nat. Biotechnol. 30 (2012) 1143-1148.
- (2012) Nat. Biotechnol. , vol.30 , pp. 1143-1148
- Martell, J.D.¹ Deerinck, T.J.² Sancak, Y.³ Poulos, T.L.⁴ Mootha, V.K.⁵ Sosinsky, G.E.⁶ Ellisman, M.H.⁷ Ting, A.Y.⁸

27
- 84891011448
- MICU1 motifs define mitochondrial calcium uniporter binding and activity
- N.E. Hoffman, H.C. Chandramoorthy, S. Shamugapriya, X. Zhang, S. Rajan, K. Mallilankaraman, R.K. Gandhirajan, R.J. Vagnozzi, L.M. Ferrer, K. Sreekrishnanilayam, K. Natarajaseenivasan, S. Vallem, T. Force, E.T. Choi, J.Y. Cheung, M. Madesh, MICU1 motifs define mitochondrial calcium uniporter binding and activity, Cell Rep. 5 (2013) 1576-1588.
- (2013) Cell Rep. , vol.5 , pp. 1576-1588
- Hoffman, N.E.¹ Chandramoorthy, H.C.² Shamugapriya, S.³ Zhang, X.⁴ Rajan, S.⁵ Mallilankaraman, K.⁶ Gandhirajan, R.K.⁷

28
- 84898628109
- Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake
- L. Wang, X. Yang, S. Li, Z. Wang, Y. Liu, J. Feng, Y. Zhu, Y. Shen, Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake, EMBO J. 33 (2014) 594-604.
- (2014) EMBO J , vol.33 , pp. 594-604
- Wang, L.¹ Yang, X.² Li, S.³ Wang, Z.⁴ Liu, Y.⁵ Feng, J.⁶ Zhu, Y.⁷ Shen, Y.⁸

29
- 84895426147
- Loss-Of-Function mutations in micu1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling
- C.V. Logan, G. Szabadkai, J.A. Sharpe, D.A. Parry, S. Torelli, A.M. Childs, M. Kriek, R. Phadke, C.A. Johnson, N.Y. Roberts, D.T. Bonthron, K.A. Pysden, T. Whyte, I. Munteanu, A.R. Foley, G. Wheway, K. Szymanska, S. Natarajan, Z.A. Abdelhamed, J.E. Morgan, H. Roper, G.W. Santen, E.H. Niks, W.L. van der Pol, D. Lindhout, A. Raffaello, D. De Stefani, J.T. den Dunnen, Y. Sun, I. Ginjaar, C.A. Sewry, M. Hurles, R. Rizzuto, U.K. Consortium, M.R. Duchen, F. Muntoni, E. Sheridan, Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling, Nat. Genet. 46 (2014) 188-193
- (2014) Nat. Genet. , vol.46 , pp. 188-193
- Logan, C.V.¹ Szabadkai, G.² Sharpe, J.A.³ Parry, D.A.⁴ Torelli, S.⁵ Childs, A.M.⁶ Kriek, M.⁷ Phadke, R.⁸ Johnson, C.A.⁹ Roberts, N.Y.¹⁰ Bonthron, D.T.¹¹ Pysden, K.A.¹² Whyte, T.¹³ Munteanu, I.¹⁴ Foley, A.R.¹⁵ Wheway, G.¹⁶ Szymanska, K.¹⁷ Natarajan, S.¹⁸ Abdelhamed, Z.A.¹⁹ Morgan, J.E.²⁰ more..

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.