Vigilin interacts with CCCTC-binding factor (CTCF) and is involved in CTCF-dependent regulation of the imprinted genes Igf2 and H19

FEBS Journal

Volumn 281, Issue 12, 2014, Pages 2713-2725

  Liu, Qiuying ^a   Yang, Bo ^a,b   Xie, Xiaoyan ^a   Wei, Ling ^a   Liu, Wenquan ^a   Yang, Wenli ^a   Ge, Yajun ^a   Zhu, Qiang ^a   Zhang, Junzhe ^a   Jiang, Lei ^a   Yu, Xiaoqin ^a   Shen, Wenyan ^a   Li, Ran ^a   Shi, Xuejiao ^a   Li, Bo ^a   Qin, Yang ^a  

^a SICHUAN UNIVERSITY   (China)

^b ZHENGZHOU UNIVERSITY   (China)

Author keywords

CCCTC binding factor; gene regulation; H19; Igf2; Vigilin

Indexed keywords

BINDING PROTEIN; HEMOGLOBIN BETA CHAIN; RNA H19; SOMATOMEDIN B; TRANSCRIPTION FACTOR CTCF; UNCLASSIFIED DRUG; VIGILIN;

ARTICLE; BETA GLOBIN GENE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE LOCUS; GENOME IMPRINTING; HELA CELL LINE; HEPG2 CELL LINE; INSULIN LIKE GROWTH FACTOR 2 GENE; ONCOGENE C MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA H19 GENE; TUMOR SUPPRESSOR GENE;

CCCTC-BINDING FACTOR; GENE REGULATION; H19; IGF2; VIGILIN;

BASE SEQUENCE; CELL LINE, TUMOR; DNA PRIMERS; GENE EXPRESSION REGULATION; GENOMIC IMPRINTING; HUMANS; INSULIN-LIKE GROWTH FACTOR II; PROTEIN BINDING; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, LONG NONCODING; RNA-BINDING PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 84902668613     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12816     Document Type: Article

References (33)

1. Phillips JE, &, Corces VG, (2009) CTCF: master weaver of the genome. Cell 137, 1194-1211.
2. Recillas-Targa F, de la Rosa-Velázquez IA, &, Soto-Reyes E, (2011) Insulation of tumor suppressor genes by the nuclear factor CTCF. Biochem Cell Biol 89, 479-488.
3. Mukhopadhyay R, (2004) Chromatin insulators and CTCF: architects of epigenetic states during development. PhD Thesis, Uppsala University.
4. Mukhopadhyay R, Yu WQ, Whitehead J, Xu JW, Lezcano M, Pack S, Kanduri C, Kanduri M, Ginjala V, Vostrov A, et al,. (2004) The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide. Genome Res 14, 1594-1602.
5. Splinter E, Heath H, Kooren J, Palstra RJ, Klous P, Grosveld F, Galjart N, &, de Laat W, (2006) CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus. Genes Dev 20, 2349-2354.
6. Szabõ PE, Tang SHE, Rentsendorj A, Pfeifer GP, &, Mann JR, (2000) Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Curr Biol 10, 607-610.
7. Filippova GN, Thienes CP, Penn BH, Cho DH, Hu YJ, Moore JM, Klesert TR, Lobanenkov VV, &, Tapscott SJ, (2001) CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus. Nat Genet 28, 335-343.
8. Filippova GN, Fagerlie S, Klenova EM, Myers C, Dehner Y, Goodwin G, Neiman PE, Collins SJ, &, Lobanenkov VV, (1996) An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol Cell Biol 16, 2802-2813.
9. Butcher DT, Mancini-DiNardo DN, Archer TK, &, Rodenhiser DI, (2004) DNA binding sites for putative methylation boundaries in the unmethylated region of the BRCA1 promoter. Int J Cancer 111, 669-678.
10. Chernukhin IV, Shamsuddin S, Robinson AF, Carne AF, Paul A, El-Kady AI, Lobanenkov VV, &, Klenova EM, (2000) Physical and functional interaction between two pluripotent proteins, the Y-box DNA/RNA-binding factor, YB-1, and the multivalent zinc finger factor, CTCF. J Biol Chem 275, 29915-29921.
11. Defossez PA, Kelly KF, Filion GJP, Pérez-Torrado R, Magdinier F, Menoni H, Nordgaard CL, Daniel JM, &, Gilson E, (2005) The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso. J Biol Chem 280, 43017-43023.
12. Lutz M, Burke LJ, Barreto G, Goeman F, Greb H, Arnold R, Schultheiß H, Brehm A, Kouzarides T, Lobanenkov V, et al,. (2000) Transcriptional repression by the insulator protein CTCF involves histone deacetylases. Nucleic Acids Res 28, 1707-1713.
13. Ishihara K, Oshimura M, &, Nakao M, (2006) CTCF-dependent chromatin insulator is linked to epigenetic remodeling. Mol Cell 23, 733-742.
14. Yao H, Brick K, Evrard Y, Xiao T, Camerini-Otero RD, &, Felsenfeld G, (2010) Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA. Genes Dev 24, 2543-2555.
15. Nativio R, Sparago A, Ito Y, Weksberg R, Riccio A, &, Murrell A, (2011) Disruption of genomic neighbourhood at the imprinted IGF2-H19 locus in Beckwith-Wiedemann syndrome and Silver-Russell syndrome. Hum Mol Genet 20, 1363-1374.
16. Wendt KS, Yoshida K, Itoh T, Bando M, Koch B, Schirghuber E, Tsutsumi S, Nagae G, Ishihara K, &, Mishiro T, (2008) Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature 451, 796-801.
17. Rubio ED, Reiss DJ, Welcsh PL, Disteche CM, Filippova GN, Baliga NS, Aebersold R, Ranish JA, &, Krumm A, (2008) CTCF physically links cohesin to chromatin. Proc Natl Acad Sci USA 105, 8309-8314.
18. Parelho V, Hadjur S, Spivakov M, Leleu M, Sauer S, Gregson HC, Jarmuz A, Canzonetta C, Webster Z, &, Nesterova T, (2008) Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell 132, 422-433.
19. Ratajczak MZ, (2012) Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a 'passkey'to cancerogenesis. Folia Histochem Cytobiol 50, 171-179.
20. Nativio R, Wendt KS, Ito Y, Huddleston JE, Uribe-Lewis S, Woodfine K, Krueger C, Reik W, Peters JM, &, Murrell A, (2009) Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet 5, e1000739.
21. Wu J, Qin Y, Li B, He W, &, Sun Z, (2008) Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma. Genomics 91, 443-450.
22. Li XR, Nong Z, Ekstrom C, Larsson E, Nordlinder H, Hofmann WJ, Trautwein C, Odenthal M, Dienes HP, Ekstrom TJ, et al,. (1997) Disrupted IGF2 promoter control by silencing of promoter P1 in human hepatocellular carcinoma. Cancer Res 57, 2048-2054.
23. Kruse C, Willkomm D, Grünweller A, Vollbrandt T, Sommer S, Busch S, Pfeiffer T, Brinkmann J, Hartmann RK, &, Müller PK, (2000) Export and transport of tRNA are coupled to a multi-protein complex. Biochem J 346, 107-115.
24. Woo HH, Yi X, Lamb T, Menzl I, Baker T, Shapiro DJ, &, Chambers SK, (2011) Posttranscriptional suppression of proto-oncogene c-fms expression by vigilin in breast cancer. Mol Cell Biol 31, 215-225.
25. Goolsby KM, &, Shapiro DJ, (2003) RNAi-mediated depletion of the 15 KH domain protein, vigilin, induces death of dividing and non-dividing human cells but does not initially inhibit protein synthesis. Nucleic Acids Res 31, 5644-5653.
26. Cunningham KS, Dodson RE, Nagel MA, Shapiro DJ, &, Schoenberg DR, (2000) Vigilin binding selectively inhibits cleavage of the vitellogenin mRNA 3?-untranslated region by the mRNA endonuclease polysomal ribonuclease 1. Proc Natl Acad Sci USA 97, 12498-12502.
27. Huertas D, Cortés A, Casanova J, &, Azorin F, (2004) Drosophila DDP1, a Multi-KH-domain protein, contributes to centromeric silencing and chromosome segregation. Curr Biol 14, 1611-1620.
28. Cortés A, Huertas D, Fanti L, Pimpinelli S, Marsellach FX, Piña B, &, Azorín F, (1999) DDP1, a single-stranded nucleic acid-binding protein of Drosophila, associates with pericentric heterochromatin and is functionally homologous to the yeast Scp160p, which is involved in the control of cell ploidy. EMBO J 18, 3820-3833.
29. Zhou J, Wang Q, Chen LL, &, Carmichael GG, (2008) On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin. RNA 14, 1773-1781.
30. Wang Q, Zhang Z, Blackwell K, &, Carmichael GG, (2005) Vigilins bind to promiscuously A-to-I-edited RNAs and are involved in the formation of heterochromatin. Curr Biol 15, 384-391.
31. Xiao T, Wallace J, &, Felsenfeld G, (2011) Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activity. Mol Cell Biol 31, 2174-2183.
32. Katz DJ, Beer MA, Levorse JM, &, Tilghman SM, (2005) Functional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control region. Mol Cell Biol 25, 3855-3863.
33. Ge YJ, Xie XY, Yang B, Cai XJ, Zhang YC, &, Qin Y, (2009) [VIGILIN involves in regulation of imprinting gene IGF2 and H19 in human hepatocellular carcinoma cell]. J Sichuan Uni(Med Sci Edi) 40, 770-774.