tRNA synthetase counteracts c-Myc to develop functional vasculature

eLife

Volumn 2014, Issue 3, 2014, Pages

  Shi, Yi ^a,b   Xu, Xiaoling ^a   Zhang, Qian ^a   Fu, Guangsen ^a   Mo, Zhongying ^a   Wang, George S ^a   Kishi, Shuji ^a   Yang, Xiang Lei ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; HISTONE DEACETYLASE; MAX PROTEIN; SERINE TRANSFER RNA LIGASE; SIRTUIN 2; VASCULOTROPIN A;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; ONCOGENE C MYC; PROTEIN BINDING; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PROTEIN FOOTPRINTING; PROTEIN PURIFICATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURFACE PLASMON RESONANCE; VASCULARIZATION; WESTERN BLOTTING; ZEBRA FISH;

EID: 84902659423     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.02349.001     Document Type: Article

References (42)

1. Amati B, Frank SR, Donjerkovic D, Taubert S. 2001. Function of the c-Myc oncoprotein in chromatin remodeling and transcription. Biochimica et Biophysica Acta 1471: M135-M145. doi: 10. 1016/S0304-419X(01)00020-8.
2. Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, Hopkins N. 2004. Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America 101: 12792-12797. doi: 10. 1073/pnas. 0403929101.
3. Atchley WR, Fitch WM. 1995. Myc and Max: molecular evolution of a family of proto-oncogene products and their dimerization partner. Proceedings of the National Academy of Sciences of the United States of America 92: 10217-10221. doi: 10. 1073/pnas. 92. 22. 10217.
4. Baudino TA, McKay C, Pendeville-Samain H, Nilsson JA, Maclean KH, White EL, Davis AC, Ihle JN, Cleveland JL. 2002. c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression. Genes & Development 16: 2530-2543. doi: 10. 1101/gad. 1024602.
5. Blackwell TK, Huang J, Ma A, Kretzner L, Alt FW, Eisenman RN, Weintraub H. 1993. Binding of myc proteins to canonical and noncanonical DNA sequences. Molecular and Cellular Biology 13: 5216-5224. doi: 10. 1128/MCB. 13. 9. 5216.
6. Blackwood EM, Eisenman RN. 1991. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 251: 1211-1217. doi: 10. 1126/science. 2006410.
7. Caramazza D, Hussein K, Siragusa S, Pardanani A, Knudson RA, Ketterling RP, Tefferi A. 2009. Chromosome 1 abnormalities in myeloid malignancies: a literature survey and karyotype-phenotype associations. European Journal of Haematology 84: 191-200. doi: 10. 1111/j. 1600-0609. 2009. 01392. x.
8. Drake CJ, Little CD. 1995. Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Proceedings of the National Academy of Sciences of the United States of America 92: 7657-7661. doi: 10. 1073/pnas. 92. 17. 7657.
9. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D. 2007. Large-scale mapping of human protein-protein interactions by mass spectrometry. Molecular Systems Biology 3: 89. doi: 10. 1038/msb4100134.
10. Finkel T, Deng CX, Mostoslavsky R. 2009. Recent progress in the biology and physiology of sirtuins. Nature 460: 587-591. doi: 10. 1038/nature08197.
11. Finnin MS, Donigian JR, Pavletich NP. 2001. Structure of the histone deacetylase SIRT2. Nature Structural Biology 8: 621-625. doi: 10. 1038/89668.
12. Foley KP, McArthur GA, Queva C, Hurlin PJ, Soriano P, Eisenman RN. 1998. Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation. The EMBO Journal 17: 774-785. doi: 10. 1093/emboj/17. 3. 774.
13. Fukui H, Hanaoka R, Kawahara A. 2009. Noncanonical activity of seryl-tRNA synthetase is involved in vascular development. Circulation Research 104: 1253-1259. doi: 10. 1161/CIRCRESAHA. 108. 191189.
14. Grandori C, Cowley SM, James LP, Eisenman RN. 2000. The Myc/Max/Mad network and the transcriptional control of cell behavior. Annual Review of Cell and Developmental Biology 16: 653-699. doi: 10. 1146/annurev. cellbio. 16. 1. 653.
15. Guarani V, Deflorian G, Franco CA, Kruger M, Phng LK, Bentley K, Toussaint L, Dequiedt F, Mostoslavsky R, Schmidt MH, Zimmermann B, Brandes RP, Mione M, Westphal CH, Braun T, Zeiher AM, Gerhardt H, Dimmeler S, Potente M. 2011. Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase. Nature 473: 234-238. doi: 10. 1038/nature09917.
16. Guo M, Schimmel P. 2013. Essential nontranslational functions of tRNA synthetases. Nature Chemical Biology 9: 145-153. doi: 10. 1038/nchembio. 1158.
17. Guo M, Yang XL, Schimmel P. 2010. New functions of aminoacyl-tRNA synthetases beyond translation. Nature Reviews Molecular Cell Biology 11: 668-674. doi: 10. 1038/nrm2956.
18. Herzog W, Muller K, Huisken J, Stainier DY. 2009. Genetic evidence for a noncanonical function of seryl-tRNA synthetase in vascular development. Circulation Research 104: 1260-1266. doi: 10. 1161/CIRCRESAHA. 108. 191718.
19. Hiratsuka M, Inoue T, Toda T, Kimura N, Shirayoshi Y, Kamitani H, Ohama E, Tahimic CG, Kurimasa A, Oshimura M. 2003. Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochemical and Biophysical Research Communications 309: 558-566. doi: 10. 1016/j. bbrc. 2003. 08. 029.
20. Hu J, Banerjee A, Goss DJ. 2005. Assembly of b/HLH/z proteins c-Myc, Max, and Mad1 with cognate DNA: importance of protein-protein and protein-DNA interactions. Biochemistry 44: 11855-11863. doi: 10. 1021/bi050206i.
21. Kim J, Lee JH, Iyer VR. 2008. Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo. PLOS ONE 3: e1798. doi: 10. 1371/journal. pone. 0001798.
22. Kim JW, Gao P, Liu YC, Semenza GL, Dang CV. 2007. Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Molecular and Cellular Biology 27: 7381-7393. doi: 10. 1128/MCB. 00440-07.
23. Kokai E, Voss F, Fleischer F, Kempe S, Marinkovic D, Wolburg H, Leithäuser F, Schmidt V, Deutsch U, Wirth T. 2009. Myc regulates embryonic vascular permeability and remodeling. Circulation Research 104: 1151-1159. doi: 10. 1161/CIRCRESAHA. 108. 191460.
24. Lennerz V, Fatho M, Gentilini C, Frye RA, Lifke A, Ferel D, Wölfel C, Huber C, Wölfel T. 2005. The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. Proceedings of the National Academy of Sciences of the United States of America 102: 16013-16018. doi: 10. 1073/pnas. 0500090102.
25. Mathew S, Murty VV, Bosl GJ, Chaganti RS. 1994. Loss of heterozygosity identifies multiple sites of allelic deletions on chromosome 1 in human male germ cell tumors. Cancer Research 54: 6265-6269.
26. McMahon SB, Van Buskirk HA, Dugan KA, Copeland TD, Cole MD. 1998. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94: 363-374. doi: 10. 1016/S0092-8674(00)81479-8.
27. McMahon SB, Wood MA, Cole MD. 2000. The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc. Molecular and Cellular Biology 20: 556-562. doi: 10. 1128/MCB. 20. 2. 556-562. 2000.
28. Mitchell EL, Santibanez-Koref MF. 1990. 1p13 is the most frequently involved band in structural chromosomal rearrangements in human breast cancer. Genes, Chromosomes & Cancer 2: 278-289. doi: 10. 1002/gcc. 2870020405.
29. Morgan R, Stebbins RD, Hecht F, Sandberg AA. 1985. The Philadelphia (Ph) chromosome in leukemia. III. Complex Ph translocation plus inversion in chronic myelocytic leukemia. Cancer Genetics and Cytogenetics 14: 23-30. doi: 10. 1016/0165-4608(85)90211-0.
30. Munn KE, Walker RA, Varley JM. 1995. Frequent alterations of chromosome 1 in ductal carcinoma in situ of the breast. Oncogene 10: 1653-1657.
31. Nagai H, Negrini M, Carter SL, Gillum DR, Rosenberg AL, Schwartz GF, Croce CM. 1995. Detection and cloning of a common region of loss of heterozygosity at chromosome 1p in breast cancer. Cancer Research 55: 1752-1757.
32. Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. 2007. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science 317: 516-519. doi: 10. 1126/science. 1143780.
33. Potente M, Ghaeni L, Baldessari D, Mostoslavsky R, Rossig L, Dequiedt F, Haendeler J, Mione M, Dejana E, Alt FW, Zeiher AM, Dimmeler S. 2007. SIRT1 controls endothelial angiogenic functions during vascular growth. Genes & Development 21: 2644-2658. doi: 10. 1101/gad. 435107.
34. Prendergast GC. 1999. Myc and Myb: are the veils beginning to lift? Oncogene 18: 2914-2915. doi: 10. 1038/sj. onc. 1202784.
35. Queva C, Hurlin PJ, Foley KP, Eisenman RN. 1998. Sequential expression of the MAD family of transcriptional repressors during differentiation and development. Oncogene 16: 967-977.
36. Schreiber-Agus N, Meng Y, Hoang T, Hou H Jnr, Chen K, Greenberg R, Cordon-Cardo C, Lee HW, DePinho RA. 1998. Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth. Nature 393: 483-487. doi: 10. 1038/31008.
37. Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, Huber LJ. 2006. Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Molecular and Cellular Biology 26: 28-38. doi: 10. 1128/MCB. 26. 1. 28-38. 2006.
38. Vaquero A, Scher MB, Lee DH, Sutton A, Cheng HL, Alt FW, Serrano L, Sternglanz R, Reinberg D. 2006. SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes & Development 20: 1256-1261. doi: 10. 1101/gad. 1412706.
39. Xu J, Zheng SL, Chang B, Smith JR, Carpten JD, Stine OC, Isaacs SD, Wiley KE, Henning L, Ewing C, Bujnovszky P, Bleeker ER, Walsh PC, Trent JM, Meyers DA, Isaacs WB. 2001. Linkage of prostate cancer susceptibility loci to chromosome 1. Human Genetics 108: 335-345. doi: 10. 1007/s004390100488.
40. Xu X, Shi Y, Yang XL. 2013. Crystal structure of human Seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes. Structure 21: 2078-2086. doi: 10. 1016/j. str. 2013. 08. 021.
41. Xu X, Shi Y, Zhang HM, Swindell EC, Marshall AG, Guo M, Kishi S, Yang XL. 2012. Unique domain appended to vertebrate tRNA synthetase is essential for vascular development. Nature Communications 3: 681. doi: 10. 1038/ncomms1686.
42. Zhou ZQ, Hurlin PJ. 2001. The interplay between Mad and Myc in proliferation and differentiation. Trends in Cell Biology 11: S10-S14. doi: 10. 1016/S0962-8924(01)02121-3.