Development of an NADPH-dependent Homophenylalanine dehydrogenase by protein engineering

ACS Synthetic Biology

Volumn 3, Issue 1, 2014, Pages 13-20

  Li, Han ^a,b   Liao, James C ^a,b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Glutamate dehydrogenase; L homophenylalanine; Protein engineering; Reductive amination; Synthetic biology

Indexed keywords

2 OXOGLUTARIC ACID; AMINOTRANSFERASE; GLUTAMATE DEHYDROGENASE; OXIDOREDUCTASE; PHENYLPYRUVIC ACID; SULFITE REDUCTASE (NADPH); 2-AMINO-4-PHENYLBUTYRIC ACID; 2-OXO-4-PHENYL-3-BUTYNOATE; ALKYNE; ALPHA-KETOGLUTARIC ACID; AMINOBUTYRIC ACID DERIVATIVE; BUTYRIC ACID DERIVATIVE; GLUTAMATE DEHYDROGENASE (NADP); NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PHENYLALANINE DEHYDROGENASE (NAD);

ARTICLE; CATALYSIS; ESCHERICHIA COLI; IN VITRO STUDY; IN VIVO STUDY; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; WILD TYPE; AMINO ACID SEQUENCE; BIOCATALYSIS; CHEMISTRY; GENETICS; KINETICS; METABOLIC ENGINEERING; METABOLISM;

ALKYNES; AMINO ACID OXIDOREDUCTASES; AMINO ACID SEQUENCE; AMINOBUTYRATES; BIOCATALYSIS; BUTYRATES; ESCHERICHIA COLI; GLUTAMATE DEHYDROGENASE (NADP+); KETOGLUTARIC ACIDS; KINETICS; METABOLIC ENGINEERING; NADP; PHENYLPYRUVIC ACIDS; PROTEIN ENGINEERING;

EID: 84902657433     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/sb400093x     Document Type: Article

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