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Volumn 41, Issue 38, 2002, Pages 11390-11397
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Single amino acid substitution in Bacillus sphaericus phenylalanine dehydrogenase dramatically increases its discrimination between phenylalanine and tyrosine substrates
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Author keywords
[No Author keywords available]
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Indexed keywords
MUTANT ENZYMES;
AMINO ACIDS;
BACTERIA;
ENZYMES;
HYDROPHOBICITY;
MUTAGENESIS;
BIOCHEMISTRY;
ALANINE;
AMINO ACID;
ASPARAGINE;
BACTERIAL ENZYME;
GLUTAMATE DEHYDROGENASE;
ISOLEUCINE;
LEUCINE;
MUTANT PROTEIN;
OXOACID;
PHENYLALANINE;
PHENYLALANINE DEHYDROGENASE;
TYROSINE;
UNCLASSIFIED DRUG;
VALINE;
AMINO ACID SUBSTITUTION;
ARTICLE;
BACILLUS;
BACILLUS BADIUS;
BACILLUS SPHAERICUS;
CLOSTRIDIUM;
CLOSTRIDIUM SYMBIOSUM;
FAST PROTEIN LIQUID CHROMATOGRAPHY;
NONHUMAN;
PRIORITY JOURNAL;
SEQUENCE HOMOLOGY;
SITE DIRECTED MUTAGENESIS;
WILD TYPE;
ALANINE;
AMINO ACID OXIDOREDUCTASES;
AMINO ACID SEQUENCE;
AMINO ACID SUBSTITUTION;
BACILLUS;
BASE SEQUENCE;
BINDING SITES;
DNA PRIMERS;
KINETICS;
MODELS, MOLECULAR;
MOLECULAR SEQUENCE DATA;
MUTAGENESIS, SITE-DIRECTED;
OLIGODEOXYRIBONUCLEOTIDES;
PHENYLALANINE;
PROTEIN CONFORMATION;
RECOMBINANT PROTEINS;
RESTRICTION MAPPING;
SEQUENCE ALIGNMENT;
SUBSTRATE SPECIFICITY;
TYROSINE;
BACILLUS BADIUS;
BACILLUS SPHAERICUS;
BACTERIA (MICROORGANISMS);
CLOSTRIDIUM;
CLOSTRIDIUM SYMBIOSUM;
POSIBACTERIA;
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EID: 0037167635
PISSN: 00062960
EISSN: None
Source Type: Journal
DOI: 10.1021/bi020196a Document Type: Article |
Times cited : (34)
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References (39)
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