Toward onset prevention of cognitive decline in adults with Down syndrome (the TOP-COG study): Study protocol for a randomized controlled trial

Trials

Volumn 15, Issue 1, 2014, Pages

  Cooper, Sally Ann ^a   Caslake, Muriel ^a   Evans, Jonathan ^a   Hassiotis, Angela ^b   Jahoda, Andrew ^a   McConnachie, Alex ^a   Morrison, Jill ^a   Ring, Howard ^c   Starr, John ^d   Stiles, Ciara ^a   Sullivan, Frank ^e  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

Alzheimer disease; Dementia; Down syndrome; Neuropsychology; Primary prevention; Simvastatin; Statin

Indexed keywords

CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN; ANTILIPEMIC AGENT;

ADAPTIVE BEHAVIOR; ADULT; ALZHEIMER DISEASE; ARTICLE; CAREGIVER; CAREGIVER BURDEN; COGNITION; CONTROLLED STUDY; DOWN SYNDROME; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DETERIORATION; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PERCEPTION; POPULATION; PRIMARY PREVENTION; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; COGNITION DISORDERS; COMPLICATION; FEASIBILITY STUDY; METHODOLOGY; NEUROPSYCHOLOGICAL TEST; ONSET AGE; PILOT STUDY; PROCEDURES; QUALITATIVE RESEARCH;

AGE OF ONSET; ALZHEIMER DISEASE; COGNITION DISORDERS; DOWN SYNDROME; FEASIBILITY STUDIES; HUMANS; HYPOLIPIDEMIC AGENTS; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PILOT PROJECTS; PRIMARY PREVENTION; QUALITATIVE RESEARCH; RESEARCH DESIGN; SIMVASTATIN;

EID: 84902649164     PISSN: None     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/1745-6215-15-202     Document Type: Article

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