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Volumn 379, Issue 9815, 2012, Pages 528-536

Memantine for dementia in adults older than 40 years with Down's syndrome (MEADOWS): A randomised, double-blind, placebo-controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

MEMANTINE; PLACEBO;

EID: 84857055024     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(11)61676-0     Document Type: Article
Times cited : (122)

References (26)
  • 1
    • 32544458799 scopus 로고    scopus 로고
    • Improved national prevalence estimates for 18 selected major birth defects - United States, 1999-2001
    • Centers for Disease Control and Prevention (CDC)
    • Centers for Disease Control and Prevention (CDC) Improved national prevalence estimates for 18 selected major birth defects - United States, 1999-2001 MMWR Morb Mortal Wkly Rep 54 2006 1301 1305
    • (2006) MMWR Morb Mortal Wkly Rep , vol.54 , pp. 1301-1305
  • 4
    • 0034125007 scopus 로고    scopus 로고
    • Incidence and course of dementia in people with Down's syndrome: Findings from a population-based study
    • DOI 10.1046/j.1365-2788.2000.00263.x
    • AJ Holland, J Hon, FA Huppert, F Stevens Incidence and course of dementia in people with Down's syndrome: findings from a population-based study J Intellect Disabil Res 44 2000 138 146 (Pubitemid 30386552)
    • (2000) Journal of Intellectual Disability Research , vol.44 , Issue.2 , pp. 138-146
    • Holland, A.J.1    Hon, J.2    Huppert, F.A.3    Stevens, F.4
  • 5
    • 71249104673 scopus 로고    scopus 로고
    • Trends in Down's syndrome live births and antenatal diagnoses in England and Wales from 1989 to 2008: Analysis of data from the National Down Syndrome Cytogenetic Register
    • JK Morris, E Alberman Trends in Down's syndrome live births and antenatal diagnoses in England and Wales from 1989 to 2008: analysis of data from the National Down Syndrome Cytogenetic Register BMJ 339 2009 b3794
    • (2009) BMJ , vol.339 , pp. 3794
    • Morris, J.K.1    Alberman, E.2
  • 6
    • 33745227251 scopus 로고    scopus 로고
    • Down's syndrome: Critical genes in a critical region
    • DOI 10.1038/441582a, PII 441582
    • CJ Epstein Down's syndrome: critical genes in a critical region Nature 441 2006 582 583 (Pubitemid 43927280)
    • (2006) Nature , vol.441 , Issue.7093 , pp. 582-583
    • Epstein, C.J.1
  • 7
    • 34548669115 scopus 로고    scopus 로고
    • Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome
    • DOI 10.1016/j.mcn.2007.07.007, PII S1044743107001698
    • J Park, EJ Yang, JH Yoon, KC Chung Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome Mol Cell Neurosci 36 2007 270 279 (Pubitemid 47418617)
    • (2007) Molecular and Cellular Neuroscience , vol.36 , Issue.2 , pp. 270-279
    • Park, J.1    Yang, E.J.2    Yoon, J.H.3    Chung, K.C.4
  • 8
    • 78349266860 scopus 로고    scopus 로고
    • Change in plasma Aβ peptides and onset of dementia in adults with Down syndrome
    • N Schupf, WB Zigman, MX Tang et al. Change in plasma Aβ peptides and onset of dementia in adults with Down syndrome Neurology 75 2010 1639 1644
    • (2010) Neurology , vol.75 , pp. 1639-1644
    • Schupf, N.1    Zigman, W.B.2    Tang, M.X.3
  • 9
    • 51849158177 scopus 로고    scopus 로고
    • The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome
    • J Wegiel, K Dowjat, W Kaczmarski et al. The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome Acta Neuropathol 116 2008 391 407
    • (2008) Acta Neuropathol , vol.116 , pp. 391-407
    • Wegiel, J.1    Dowjat, K.2    Kaczmarski, W.3
  • 11
    • 74049098309 scopus 로고    scopus 로고
    • Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains
    • DE Kuhn, GJ Nuovo, AV Terry Jr et al. Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains J Biol Chem 285 2010 1529 1543
    • (2010) J Biol Chem , vol.285 , pp. 1529-1543
    • Kuhn, D.E.1    Nuovo, G.J.2    Terry, Jr.A.V.3
  • 16
    • 0001788650 scopus 로고    scopus 로고
    • Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease - A unified glutamatergic hypothesis on the mechanism of action
    • W Danysz, CG Parsons, HJ Mobius, A Stoffler, G Quack Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease - a unified glutamatergic hypothesis on the mechanism of action Neurotoxicity Res 2 2000 85 97
    • (2000) Neurotoxicity Res , vol.2 , pp. 85-97
    • Danysz, W.1    Parsons, C.G.2    Mobius, H.J.3    Stoffler, A.4    Quack, G.5
  • 17
    • 0030942897 scopus 로고    scopus 로고
    • Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome
    • DOI 10.1016/S0024-3205(97)00067-2, PII S0024320597000672
    • D Risser, G Lubec, N Cairns, M Herrera-Marschitz Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome Life Sci 60 1997 1231 1237 (Pubitemid 27191762)
    • (1997) Life Sciences , vol.60 , Issue.15 , pp. 1231-1237
    • Risser, D.1    Lubec, G.2    Cairns, N.3    Herrera-Marschitz, M.4
  • 18
    • 0042829429 scopus 로고    scopus 로고
    • Redox regulation of neuronal migration in a down syndrome model
    • DOI 10.1016/S0891-5849(03)00329-0
    • TN Behar, CA Colton Redox regulation of neuronal migration in a Down Syndrome model Free Radic Biol Med 35 2003 566 575 (Pubitemid 37101124)
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.6 , pp. 566-575
    • Behar, T.N.1    Colton, C.A.2
  • 21
    • 43649094588 scopus 로고    scopus 로고
    • Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test
    • DOI 10.1038/sj.npp.1301535, PII 1301535
    • AC Costa, JJ Scott-McKean, MR Stasko Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test Neuropsychopharmacology 33 2008 1624 1632 (Pubitemid 351684704)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.7 , pp. 1624-1632
    • Costa, A.C.S.1    Scott-McKean, J.J.2    Stasko, M.R.3
  • 22
    • 77954972900 scopus 로고    scopus 로고
    • Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome
    • N Rueda, M Llorens-Martín, J Flórez et al. Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome J Alzheimers Dis 21 2010 277 290
    • (2010) J Alzheimers Dis , vol.21 , pp. 277-290
    • Rueda, N.1    Llorens-Martín, M.2    Flórez, J.3
  • 23
    • 79955723158 scopus 로고    scopus 로고
    • Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome
    • J Lockrow, H Boger, H Bimonte-Nelson, AC Granholm Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome Behav Brain Res 221 2011 610 622
    • (2011) Behav Brain Res , vol.221 , pp. 610-622
    • Lockrow, J.1    Boger, H.2    Bimonte-Nelson, H.3    Granholm, A.C.4
  • 24
    • 0038369866 scopus 로고    scopus 로고
    • Plasma amyloid β protein 1-42 levels are increased in old Down Syndrome but not in young Down Syndrome
    • DOI 10.1016/S0304-3940(03)00275-1
    • PD Mehta, SP Mehta, B Fedor, BA Patrick, M Emmerling, AJ Dalton Plasma amyloid β protein 1-42 levels are increased in old Down syndrome but not in young Down syndrome Neurosci Lett 342 2003 155 158 (Pubitemid 36570341)
    • (2003) Neuroscience Letters , vol.342 , Issue.3 , pp. 155-158
    • Mehta, P.D.1    Mehta, S.P.2    Fedor, B.3    Patrick, B.A.4    Emmerling, M.5    Dalton, A.J.6
  • 26
    • 77952752313 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms elucidating neurocognitive basis of functional impairments associated with intellectual disability in Down syndrome
    • M Rachidi, C Lopes Molecular and cellular mechanisms elucidating neurocognitive basis of functional impairments associated with intellectual disability in Down syndrome Am J Intellect Dev Disabil 115 2010 83 112
    • (2010) Am J Intellect Dev Disabil , vol.115 , pp. 83-112
    • Rachidi, M.1    Lopes, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.